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Study on site selection planning of urban electric vehicle charging station
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作者 刘娜 CHENG Jiaxin DUAN Yukai 《High Technology Letters》 EI CAS 2024年第1期75-84,共10页
The large-scale development of electric vehicles(EVs)requires numerous charging stations to serve them,and the charging stations should be reasonably laid out and planned according to the charging demand of electric v... The large-scale development of electric vehicles(EVs)requires numerous charging stations to serve them,and the charging stations should be reasonably laid out and planned according to the charging demand of electric vehicles.Considering the costs of both operators and users,a site selection model for optimal layout planning of charging stations is constructed,and a queuing theory approach is used to determine the charging pile configuration to meet the charging demand in the planning area.To solve the difficulties of particle swarm global optimization search,the improved random drift particle swarm optimization(IRDPSO)and Voronoi diagram are used to jointly solve for the optimal layout of electric vehicles.The final arithmetic analysis verifies the feasibility and practicality of the model and algorithm,and the results show that the total social cost is minimized when the charging station is 9,the location of the charging station is close to the center of gravity and the layout is reasonable. 展开更多
关键词 charging station electric vehicle(EV) improved random drift particle swarm optimization(IRDPSO) optimal planning
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Optimal search path planning of UUV in battlefeld ambush scene
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作者 Wei Feng Yan Ma +3 位作者 Heng Li Haixiao Liu Xiangyao Meng Mo Zhou 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第2期541-552,共12页
Aiming at the practical application of Unmanned Underwater Vehicle(UUV)in underwater combat,this paper proposes a battlefield ambush scene with UUV considering ocean current.Firstly,by establishing these mathematical ... Aiming at the practical application of Unmanned Underwater Vehicle(UUV)in underwater combat,this paper proposes a battlefield ambush scene with UUV considering ocean current.Firstly,by establishing these mathematical models of ocean current environment,target movement,and sonar detection,the probability calculation methods of single UUV searching target and multiple UUV cooperatively searching target are given respectively.Then,based on the Hybrid Quantum-behaved Particle Swarm Optimization(HQPSO)algorithm,the path with the highest target search probability is found.Finally,through simulation calculations,the influence of different UUV parameters and target parameters on the target search probability is analyzed,and the minimum number of UUVs that need to be deployed to complete the ambush task is demonstrated,and the optimal search path scheme is obtained.The method proposed in this paper provides a theoretical basis for the practical application of UUV in the future combat. 展开更多
关键词 Battlefield ambush Optimal search path planning UUV path planning Probability of cooperative search
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Cooperative Path Dynamic Planning Model of UCAV Team Based on Global Optimization Method
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作者 Xiao-Cheng Zhou Jian-Gang Yan Rong Chen 《Journal of Electronic Science and Technology》 CAS 2012年第4期363-367,共5页
Cooperative path dynamic planning of a UCAV (unmanned combat air vehicle) team not only considers the capability of task requirement of single UCAV, but also considers the cooperative dynamic connection among member... Cooperative path dynamic planning of a UCAV (unmanned combat air vehicle) team not only considers the capability of task requirement of single UCAV, but also considers the cooperative dynamic connection among members of the UCAV team. A cooperative path dynamic planning model of the UCAV team by applying a global optimization method is discussed in this paper and the corresponding model is built and analyzed. By the example simulation, the reasonable result acquired indicates that the model could meet dynamic planning demand under the circumstance of membership functions. The model is easy to be realized and has good practicability. 展开更多
关键词 Cooperative path dynamic planning global optimization unmanned combat air vehicle team.
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Inexact dynamic optimization for groundwater remediation planning and risk assessment under uncertainty
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《Global Geology》 1998年第1期22-23,共2页
关键词 Inexact dynamic optimization for groundwater remediation planning and risk assessment under uncertainty
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Effect of water and fertilizer coupling optimization test on water use efficiency of rice in black soil regions 被引量:4
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作者 LIN Yanyu ZHANG Zhongxue +1 位作者 XU Dan NIE Tangzhe 《排灌机械工程学报》 EI CSCD 北大核心 2016年第2期151-156,共6页
How to improve the water use efficiency of rice in black soil regions was studied. The black soil region in paddy fields was chosen as the research object. The research showed the fertilizer coupling mathematical mode... How to improve the water use efficiency of rice in black soil regions was studied. The black soil region in paddy fields was chosen as the research object. The research showed the fertilizer coupling mathematical model with N,P,K,irrigation water( W) and water use efficiency( WUE),which was set up under the condition of controlled irrigation with quadratic D- 416 optimized saturation design. The results show that the decending order of single factor' s influence on the WUE was N,K,P and W. All the interactions between N&P,N&K,N&W,K&P,P&W and K&W on the WUE were raised initially,and when reached a certain value,they began to decline. The decending order of each interaction on the WUE was K&P,K&W,N&K,N&P,P&W and N&W. When the WUE was targeted within 1. 8- 2. 5 kg / km^3,an optimized proportion plan was obtained in the 95% confidence interval,i. e. N 87. 76- 103. 32 kg / hm^2,K_2 O 52. 37- 66. 53 kg / hm^2 and P_2O_536. 80- 46. 71 kg / hm^2. Furthermore,the late tillering of the soil moisture content was 70. 07%- 72. 57% of the saturated moisture content. 展开更多
关键词 black soil RICE controlled irrigation water and fertilizer optimization plan WUE
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Application of Interval Algorithm in Rural Power Network Planning
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作者 GU Zhuomu ZHAO Yulin 《Journal of Northeast Agricultural University(English Edition)》 CAS 2009年第3期57-60,共4页
Rural power network planning is a complicated nonlinear optimized combination problem which based on load forecasting results, and its actual load is affected by many uncertain factors, which influenced optimization r... Rural power network planning is a complicated nonlinear optimized combination problem which based on load forecasting results, and its actual load is affected by many uncertain factors, which influenced optimization results of rural power network planning. To solve the problems, the interval algorithm was used to modify the initial search method of uncertainty load mathematics model in rural network planning. Meanwhile, the genetic/tabu search combination algorithm was adopted to optimize the initialized network. The sample analysis results showed that compared with the certainty planning, the improved method was suitable for urban medium-voltage distribution network planning with consideration of uncertainty load and the planning results conformed to the reality. 展开更多
关键词 rural power network optimization planning load uncertainty interval algorithm genetic/tabu search combination algorithm
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Data-driven optimization for fine water injection in a mature oil field
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作者 JIA Deli LIU He +4 位作者 ZHANG Jiqun GONG Bin PEI Xiaohan WANG Quanbin YANG Qinghai 《Petroleum Exploration and Development》 2020年第3期674-682,共9页
Based on the traditional numerical simulation and optimization algorithms,in combination with the layered injection and production"hard data"monitored at real time by automatic control technology,a systemati... Based on the traditional numerical simulation and optimization algorithms,in combination with the layered injection and production"hard data"monitored at real time by automatic control technology,a systematic approach for detailed water injection design using data-driven algorithms is proposed.First the data assimilation technology is used to match geological model parameters under the constraint of observed well dynamics;the flow relationships between injectors and producers in the block are calculated based on automatic identification method for layered injection-production flow relationship;multi-layer and multi-direction production splitting technique is used to calculate the liquid and oil production of producers in different layers and directions and obtain quantified indexes of water injection effect.Then,machine learning algorithms are applied to evaluate the effectiveness of water injection in different layers of wells and to perform the water injection direction adjustment.Finally,the particle swarm algorithm is used to optimize the detailed water injection plan and to make production predictions.This method and procedure make full use of the automation and intelligence of data-driven and machine learning algorithms.This method was used to match the data of a complex faulted reservoir in eastern China,achieving a fitting level of 85%.The cumulative oil production in the example block for 12 months after optimization is 8.2%higher than before.This method can help design detailed water injection program for mature oilfields. 展开更多
关键词 zonal water injection fine water injection evaluation index optimization plan big data DATA-DRIVEN artificial intelligence
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Generative Adversarial Network Based Heuristics for Sampling-Based Path Planning 被引量:5
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作者 Tianyi Zhang Jiankun Wang Max Q.-H.Meng 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2022年第1期64-74,共11页
Sampling-based path planning is a popular methodology for robot path planning.With a uniform sampling strategy to explore the state space,a feasible path can be found without the complex geometric modeling of the conf... Sampling-based path planning is a popular methodology for robot path planning.With a uniform sampling strategy to explore the state space,a feasible path can be found without the complex geometric modeling of the configuration space.However,the quality of the initial solution is not guaranteed,and the convergence speed to the optimal solution is slow.In this paper,we present a novel image-based path planning algorithm to overcome these limitations.Specifically,a generative adversarial network(GAN)is designed to take the environment map(denoted as RGB image)as the input without other preprocessing works.The output is also an RGB image where the promising region(where a feasible path probably exists)is segmented.This promising region is utilized as a heuristic to achieve non-uniform sampling for the path planner.We conduct a number of simulation experiments to validate the effectiveness of the proposed method,and the results demonstrate that our method performs much better in terms of the quality of the initial solution and the convergence speed to the optimal solution.Furthermore,apart from the environments similar to the training set,our method also works well on the environments which are very different from the training set. 展开更多
关键词 Generative adversarial network(GAN) optimal path planning robot path planning sampling-based path planning
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Evolutionary Trajectory Planning for an Industrial Robot 被引量:6
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作者 R.Saravanan S.Ramabalan +1 位作者 C.Balamurugan A.Subash 《International Journal of Automation and computing》 EI 2010年第2期190-198,共9页
This paper presents a novel general method for computing optimal motions of an industrial robot manipulator (AdeptOne XL robot) in the presence of fixed and oscillating obstacles. The optimization model considers th... This paper presents a novel general method for computing optimal motions of an industrial robot manipulator (AdeptOne XL robot) in the presence of fixed and oscillating obstacles. The optimization model considers the nonlinear manipulator dynamics, actuator constraints, joint limits, and obstacle avoidance. The problem has 6 objective functions, 88 variables, and 21 constraints. Two evolutionary algorithms, namely, elitist non-dominated sorting genetic algorithm (NSGA-II) and multi-objective differential evolution (MODE), have been used for the optimization. Two methods (normalized weighting objective functions and average fitness factor) are used to select the best solution tradeoffs. Two multi-objective performance measures, namely solution spread measure and ratio of non-dominated individuals, are used to evaluate the Pareto optimal fronts. Two multi-objective performance measures, namely, optimizer overhead and algorithm effort, are used to find the computational effort of the optimization algorithm. The trajectories are defined by B-spline functions. The results obtained from NSGA-II and MODE are compared and analyzed. 展开更多
关键词 Multi-objective optimal trajectory planning oscillating obstacles elitist non-dominated sorting genetic algorithm (NSGA-II) multi-objective differential evolution (MODE) multi-objective performance metrics.
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Application of Optimal-Jerk Trajectory Planning in Gait-balance Training Robot 被引量:1
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作者 Fu Yuan Diansheng Chen +3 位作者 Chenghang Pan Jun Du Xiaodong Wei Min Wang 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2022年第1期50-61,共12页
To accommodate the gait and balance disorder of the elderly with age progression and the occurrence of various senile diseases,this paper proposes a novel gait balance training robot(G-Balance)based on a six degree-of... To accommodate the gait and balance disorder of the elderly with age progression and the occurrence of various senile diseases,this paper proposes a novel gait balance training robot(G-Balance)based on a six degree-of-freedom parallel platform.Using the platform movement and IMU wearable sensors,two training modes,i.e.,active and passive,are developed to achieve vestibular stimulation.Virtual reality technology is applied to achieve visual stimulation.In the active training mode,the elderly actively exercises to control the posture change of the platform and the switching of the virtual scene.In the passive training mode,the platform movement is combined with the virtual scene to simulate bumpy environments,such as earthquakes,to enhance the human anti-interference ability.To achieve a smooth switching of the scene,continuous speed and acceleration of the platform motion are required in some scenarios,in which a trajectory planning algorithm is applied.This paper describes the application of the trajectory planning algorithm in the balance training mode and the optimization of jerk(differential of acceleration)based on cubic spline planning,which can reduce impact on the joint and enhance stability. 展开更多
关键词 Gait and balance training robot Balance training mode Optimal trajectory planning
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Fuzzy linear model for production optimization of mining systems with multiple entities 被引量:1
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作者 Slobodan Vujic Tomo Benovic +3 位作者 Igor Miljanovic Marjan Hudej Aleksandar Milutinovic Petar Pavlovic 《International Journal of Minerals,Metallurgy and Materials》 SCIE EI CAS CSCD 2011年第6期633-637,共5页
Planning and production optimization within multiple mines or several work sites (entities) mining systems by using fuzzy linear programming (LP) was studied. LP is the most commonly used operations research metho... Planning and production optimization within multiple mines or several work sites (entities) mining systems by using fuzzy linear programming (LP) was studied. LP is the most commonly used operations research methods in mining engineering. After the introductory review of properties and limitations of applying LP, short reviews of the general settings of deterministic and fuzzy LP models are presented. With the purpose of comparative analysis, the application of both LP models is presented using the example of the Bauxite Basin Niksic with five mines. After the assessment, LP is an efficient mathematical modeling tool in production planning and solving many other single-criteria optimization problems of mining engineering. After the comparison of advantages and deficiencies of both deterministic and fuzzy LP models, the conclusion presents benefits of the fuzzy LP model but is also stating that seeking the optimal plan of production means to accomplish the overall analysis that will encompass the LP model approaches. 展开更多
关键词 linear programming fuzzy set theory optimization production planning bauxite mines
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Optimal control of stretching process of flexible solar arrays on spacecraft based on a hybrid optimization strategy 被引量:2
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作者 Qijia Yao Xinsheng Ge 《Theoretical & Applied Mechanics Letters》 CAS CSCD 2017年第4期258-263,共6页
The optimal control of multibody spacecraft during the stretching process of solar arrays is investigated,and a hybrid optimization strategy based on Gauss pseudospectral method(GPM) and direct shooting method(DSM... The optimal control of multibody spacecraft during the stretching process of solar arrays is investigated,and a hybrid optimization strategy based on Gauss pseudospectral method(GPM) and direct shooting method(DSM) is presented. First, the elastic deformation of flexible solar arrays was described approximately by the assumed mode method, and a dynamic model was established by the second Lagrangian equation. Then, the nonholonomic motion planning problem is transformed into a nonlinear programming problem by using GPM. By giving fewer LG points, initial values of the state variables and control variables were obtained. A serial optimization framework was adopted to obtain the approximate optimal solution from a feasible solution. Finally, the control variables were discretized at LG points, and the precise optimal control inputs were obtained by DSM. The optimal trajectory of the system can be obtained through numerical integration. Through numerical simulation, the stretching process of solar arrays is stable with no detours, and the control inputs match the various constraints of actual conditions.The results indicate that the method is effective with good robustness. 展开更多
关键词 Motion planning Multibody spacecraft Optimal control Gauss pseudospectral method Direct shooting method
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Optimal Planning of Hybrid AC/DC Low-voltage Distribution Networks Considering DC Conversion of Three-phase Four-wire Low-voltage AC Systems
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作者 Bo Zhang Lu Zhang +2 位作者 Wei Tang Gen Li Chen Wang 《Journal of Modern Power Systems and Clean Energy》 SCIE EI CSCD 2024年第1期141-153,共13页
The increasing integration of distributed household photovoltaics(PVs)and electric vehicles(EVs)may further ag gravate voltage violations and unbalance of low-voltage distribu tion networks(LVDNs).DC distribution netw... The increasing integration of distributed household photovoltaics(PVs)and electric vehicles(EVs)may further ag gravate voltage violations and unbalance of low-voltage distribu tion networks(LVDNs).DC distribution networks can increase the accommodation of PVs and EVs and mitigate mutilple pow er quality problems by the flexible power regulation capability of voltage source converters.This paper proposes schemes to es tablish hybrid AC/DC LVDNs considering the conversion of the existing three-phase four-wire low-voltage AC systems to DC op eration.The characteristics and DC conversion constraints of typical LVDNs are analyzed.In addition,converter configura tions for typical LVDNs are proposed based on the three-phase four-wire characteristics and quantitative analysis of various DC configurations.Moreover,an optimal planning method of hybrid AC/DC LVDNs is proposed,which is modeled as a bi-level programming model considering the annual investments and three-phase unbalance.Simulations are conducted to verify the effectiveness of the proposed optimal planning method.Sim ulation results show that the proposed optimal planning method can increase the integration of PVs while simultaneously reduc ing issues related to voltage violation and unbalance. 展开更多
关键词 Optimal planning low-voltage distribution net work three-phase unbalance DC conversion
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Intelligent Optimization-Based Production Planning and Simulation Analysis for Steelmaking and Continuous Casting Process 被引量:14
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作者 ZHU Dao-fei ZHENG Zhong GAO Xiao-qiang 《Journal of Iron and Steel Research(International)》 SCIE EI CAS CSCD 2010年第9期19-24,30,共7页
Aiming at the limitations of the traditional mathematical model for production planning, a novel optimization model is proposed to improve the efficiency and performance for production planning in steelmaking and cont... Aiming at the limitations of the traditional mathematical model for production planning, a novel optimization model is proposed to improve the efficiency and performance for production planning in steelmaking and continuous casting (SCC) process. The optimization model combined with parallel-backward inferring algorithm and genetic algorithm is described. To analyze and evaluate the production plans, a simulation model based on cellular automata is presented. And then, the integrated system including the production plan optimization model and the simulation model is introduced to evaluate and adjust the production plan on-line. The test with production data in a steel plant shows that the optimization model demonstrates ability to deal with time uncertainty in production planning and to set up a conflict-free production plan, and the integrated system provides a useful tool for dynamically drawing and adjusting a production plan on-line. The average staying time of the production plan is about 5% shorter than that in a practical process. 展开更多
关键词 steelmaking-continuous casting production plan optimization genetic algorithm cellular automata
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Development modes analysis of renewable energy power generation in North Africa 被引量:5
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作者 Liang Zhao Ruoying Yu +3 位作者 Zhe Wang Wei Yang Linan Qu Weidong Chen 《Global Energy Interconnection》 2020年第3期237-246,共10页
North African countries generally have strategic demands for energy transformation and sustainable development.Renewable energy development is important to achieve this goal.Considering three typical types of renewabl... North African countries generally have strategic demands for energy transformation and sustainable development.Renewable energy development is important to achieve this goal.Considering three typical types of renewable energies—wind,photovoltaic(PV),and concentrating solar power(CSP)—an optimal planning model is established to minimize construction costs and power curtailment losses.The levelized cost of electricity is used as an index for assessing economic feasibility.In this study,wind and PV,wind/PV/CSP,and transnational interconnection modes are designed for Morocco,Egypt,and Tunisia.The installed capacities of renewable energy power generation are planned through the time sequence production simulation method for each country.The results show that renewable energy combined with power generation,including the CSP mode,can improve reliability of the power supply and reduce the power curtailment rate.The transnational interconnection mode can help realize mutual benefits of renewable energy power,while the apportionment of electricity prices and trading mechanisms are very important and are related to economic feasibility;thus,this mode is important for the future development of renewable energy in North Africa. 展开更多
关键词 North Africa Renewable energy Wind power generation Solar energy generation Transnational interconnection Optimal planning Levelized cost of electricity
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LINEAR SEARCH FOR A BROWNIAN TARGET MOTION 被引量:3
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作者 A.B.El-Rayes AbdEl-MoneimA.Mohamed Hamdy M.Abou Gabal 《Acta Mathematica Scientia》 SCIE CSCD 2003年第3期321-327,共7页
A target is assumed to move according to a Brownian motion on the real line. The searcher starts from the origin and moves in the two directions from the starting point. The object is to detect the target. The purpose... A target is assumed to move according to a Brownian motion on the real line. The searcher starts from the origin and moves in the two directions from the starting point. The object is to detect the target. The purpose of this paper is to find the conditions under which the expected value of the first meeting time of the searcher and the target is finite, and to show the existence of a search plan which made this expected value minimum. 展开更多
关键词 Brownian process expected value linear search optimal search plan
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Novel Accelerating Life Test Method and Its Application by Combining Constan Stress and Progressive Stress 被引量:1
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作者 Wen-Hua Chen Fan Yang +2 位作者 Ping Qian Jun Pan Qing-Chuan He 《Chinese Journal of Mechanical Engineering》 SCIE EI CAS CSCD 2018年第5期17-24,共8页
Constant stress accelerated life tests(ALTs) can be applied to obtain a high estimation accuracy of reliability measure?ments, but these are time?consuming tests. Progressive stress ALTs can yield failures more quickl... Constant stress accelerated life tests(ALTs) can be applied to obtain a high estimation accuracy of reliability measure?ments, but these are time?consuming tests. Progressive stress ALTs can yield failures more quickly but cannot guaran tee the estimation accuracy of reliability measurements. In this paper, a progressive?constant combination stress ALT is proposed to combine the merits of both tests. The optimal plan, in which the design variables are the initial pro?gressive stress level, the progressive stress ramp rate, the sample allocation proportion of the progressive stress and the constant stress level, is determined using the principle of minimizing the asymptotic variance of the maximum likelihood estimator of the natural log reliable life for the connectors. A comparison between the optimal PCCSALT plan and the CSALT plan with the same sample size and estimation accuracy shows that the test time is reduced by 13.59% by applying the PCCSALT. 展开更多
关键词 Constant stress Progressive stress Accelerated life test Optimal test plan Reliability test
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PLANNED LEAD TIME OPTIMIZATION IN MATERIAL REQUIREMENT PLANNING ENVIRONMENT FOR MULTILEVEL PRODUCTION SYSTEMS 被引量:1
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作者 Faicel HNAIEN Alexandre DOLGUI Mohamed-Aly OULD LOULY 《Journal of Systems Science and Systems Engineering》 SCIE EI CSCD 2008年第2期132-155,共24页
This paper deals with the problem of planned lead time calculation in a Material Requirement Planning (MRP) environment under stochastic lead times. The objective is to minimize the sum of holding and backlogging co... This paper deals with the problem of planned lead time calculation in a Material Requirement Planning (MRP) environment under stochastic lead times. The objective is to minimize the sum of holding and backlogging costs. The proposed approach is based on discrete time inventory control where the decision variables are integer. Two types of systems are considered: multi-level serial-production and assembly systems. For the serial production systems (one type of component at each level), a mathematical model is suggested. Then, it is proven that this model is equivalent to the well known discrete Newsboy Model. This directly provides the optimal values for the planned lead times. For multilevel assembly systems, a dedicated model is proposed and some properties of the decision variables and objective function are proven. These properties are used to calculate lower and upper limits on the decision variables and lower and upper bounds on the objective function. The obtained limits and bounds open the possibility to develop an efficient optimization algorithm using, for example, a Branch and Bound approach. The paper presents the proposed models in detail with corresponding proofs and se'~eral numerical examples. Some advantages of the suggested models and perspectives of this research are discussed. 展开更多
关键词 Multilevel assembly and production control model planned lead time optimization systems MRP random lead times discrete inventory
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Inference and optimal design on step-stress partially accelerated life test for hybrid system with masked data
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作者 SHI Xiaolin LU Pu SHI Yimin 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2018年第5期1089-1100,共12页
Under Type-Ⅱ progressively hybrid censoring, this paper discusses statistical inference and optimal design on stepstress partially accelerated life test for hybrid system in presence of masked data. It is assumed tha... Under Type-Ⅱ progressively hybrid censoring, this paper discusses statistical inference and optimal design on stepstress partially accelerated life test for hybrid system in presence of masked data. It is assumed that the lifetime of the component in hybrid systems follows independent and identical modified Weibull distributions. The maximum likelihood estimations(MLEs)of the unknown parameters, acceleration factor and reliability indexes are derived by using the Newton-Raphson algorithm. The asymptotic variance-covariance matrix and the approximate confidence intervals are obtained based on normal approximation to the asymptotic distribution of MLEs of model parameters. Moreover,two bootstrap confidence intervals are constructed by using the parametric bootstrap method. The optimal time of changing stress levels is determined under D-optimality and A-optimality criteria.Finally, the Monte Carlo simulation study is carried out to illustrate the proposed procedures. 展开更多
关键词 hybrid system step-stress partially accelerated life test Type-Ⅱ progressively hybrid censored and masked data statistical inference optimal test plan
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Metabolic flux simulation of microbial systems based on optimal planning algorithms
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作者 Chen Yang Boyuan Xue +2 位作者 Yiming Zhang Shaojie Wang Haijia Su 《Green Chemical Engineering》 EI CSCD 2023年第2期146-159,共14页
The genomic scale metabolic networks of the microorganisms can be constructed based on their genome se-quences,functional annotations,and biochemical reactions,reflecting almost all of the metabolic functions.Mathemat... The genomic scale metabolic networks of the microorganisms can be constructed based on their genome se-quences,functional annotations,and biochemical reactions,reflecting almost all of the metabolic functions.Mathematical simulations of metabolic fluxes could make these functions be visualized,thereby providing guidance for rational engineering design and experimental operations.This review summarized recently devel-oped flux simulation algorithms of microbial systems.For the single microbial systems,the optimal planning algorithm has low complexity because there is no interaction between microorganisms,and it can quickly simulate the stable metabolic states through the pseudo-steady hypothesis.Besides,the experimental conditions of single microbial systems are easier to reach or close to the optimal states of simulation,compared with pol-ymicrobial systems.The polymicrobial culture systems could outcompete the single microbial systems as they could relieve metabolic pressure through metabolic division,resource exchange,and complex substrate co-utilization.Besides,they provide varieties of intracellular production environments,which render them the po-tential to achieve efficient bioproduct synthesis.However,due to the quasi-steady hypothesis that restricts the simulation of the dynamic processes of microbial interactions and the algorithm complexity,there are few re-searches on simulation algorithms of polymicrobial metabolic fluxes.Therefore,this review also analyzed and combed the microbial interactions based on the commonly used hypothesis of maximizing growth rates,and studied the strategies of coupling interactions with optimal planning simulations for metabolism.Finally,this review provided new insights into the genomic scale metabolic flux simulations of polymicrobial systems. 展开更多
关键词 Optimal planning algorithm Metabolic flux simulation Microbial system INTERACTION
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