Bowel preparation protocol for hospitalized patients ages 50 years or older:A randomized controlled trial

BACKGROUND The incidence and mortality rate of colorectal cancer progressively increase with age and become particularly prominent after the age of 50 years.Therefore,the population that is≥50 years in age requires long-term and regular colonoscopies.Uncomfortable bowel preparation is the main reason preventing patients from undergoing regular colonoscopies.The standard bowel preparation regimen of 4-L polyethylene glycol(PEG)is effective but poorly tolerated.AIM To investigate an effective and comfortable bowel preparation regimen for hospitalized patients≥50 years in age.METHODS Patients were randomly assigned to group 1(2-L PEG+30-mL lactulose+a lowresidue diet)or group 2(4-L PEG).Adequate bowel preparation was defined as a Boston bowel preparation scale(BBPS)score of≥6,with a score of≥2 for each segment.Non-inferiority was prespecified with a margin of 10%.Additionally,the degree of comfort was assessed based on the comfort questionnaire.RESULTS The proportion of patients with a BBPS score of≥6 in group 1 was not significantly different from that in group 2,as demonstrated by intention-to-treat(91.2%vs 91.0%,P=0.953)and per-protocol(91.8%vs 91.0%,P=0.802)analyses.Furthermore,in patients≥75 years in age,the proportion of BBPS scores of≥6 in group 1 was not significantly different from that in group 2(90.9%vs 97.0%,P=0.716).Group 1 had higher comfort scores(8.85±1.162 vs 7.59±1.735,P<0.001),longer sleep duration(6.86±1.204 h vs 5.80±1.730 h,P<0.001),and fewer awakenings(1.42±1.183 vs 2.04±1.835,P=0.026)than group 2.CONCLUSION For hospitalized patients≥50 years in age,the bowel preparation regimen comprising 2-L PEG+30-mL lactulose+a low-residue diet produced a cleanse that was as effective as the 4-L PEG regimen and even provided better comfort.

The Prevalence and Risk Factors Associated with Otitis Media in Children under Five Years of Age in Mogadishu, Somalia: A Hospital-Based Cross-Sectional Study

Background: Otitis media (OM) is highly prevalent and is one of the most important causes of preventable hearing loss in developing countries and it may have long-term impacts on the children. Several hospital-based cross-sectional studies have been conducted in East African countries to assess the prevalence of OM;however, no similar studies have been conducted in Somalia. Therefore, we conducted a hospital-based cross-sectional study to identify the prevalence and the underlying risk factors of OM among children under the age of five in Mogadishu, Somalia. Methodology: A hospital-based cross-sectional study was conducted from July 2022 to November 2022 at three main hospitals in Mogadishu, Somalia. A total of 384 children aged less than 5 years were included. Parents of these children were interviewed with a questionnaire and a clinical examination was performed for each child. The Statistical Package for Social Sciences, SPSS (Version 22, IBM, Inc.), was used for the statistical analysis. Result: The prevalence of otitis media among the 384 children recruited was 31.25% (120/384). Otitis media was significantly associated with age less than one year (P = 0.006), malnutrition (P Conclusion: In summary, the present study found that otitis media was highly prevalent (31.25%) in Mogadishu, Somalia. The majority of the affected children were younger than one year. Age of the child, malnutrition, upper respiratory tract infections, feeding in lying position, and dripping something into a child’s ear were found to significantly increase the risk of developing otitis media in children. In contrast, breastfeeding for more than one year has been found to reduce the risk of developing otitis media in children.

Effect of a Nutrition Education Intervention on Food Safety Knowledge, Attitudes and Practices of Mothers of Children under 5 Years in the Peri-Urban Areas of Bobo-Dioulasso: Before and after Study

Background: This study assessed the effect of a nutrition education intervention. This intervention aimed to improve the knowledge, attitudes, and practices of mothers on food safety in the peri-urban areas of Bobo-Dioulasso in Burkina Faso. Methods: A total of 243 mothers of children under 5 years in the peri-urban of Bobo-Dioulasso were administered the FAO questionnaire for food safety knowledge, attitudes, and practices assessment during two cross-sectional surveys, before and after the intervention, in January and October 2017. The intervention included two components consisting of a theoretical phase (counselling and discussion) and cooking demonstrations implemented for ten months. To account for the before-and-after design of the study, the McNemar’s test was used to assess the effect of the intervention on food safety KAP of mothers of children under 5 years. Results: The mean age of mothers was 29 ± 6.2 years and 50.6% of them were between 20 and 29 years old. One for knowledge (cooking thoroughly with, p-value = 0.0001) and another for attitudes (perceived benefits of reheating leftovers before eating them, p-value = 0.0001), significantly increased after the intervention. In terms of food safety practices, all the indicators (cleaning of dirty surfaces, plates and utensils and storage of perishable foods) significantly increased (all p = 0.0001 Conclusion: This study provided some evidence of an effective nutrition education intervention for improving maternal KAP on food safety for their child’s feeding.

Colorectal cancer’s burden attributable to a diet high in processed meat in the Belt and Road Initiative countries

BACKGROUND Colorectal cancer(CRC)plays a significant role in morbidity,mortality,and economic cost in the Belt and Road Initiative(“B and R”)countries.In addition,these countries have a substantial consumption of processed meat.However,the burden and trend of CRC in relation to the consumption of a diet high in processed meat(DHPM-CRC)in these“B and R”countries remain unknown.AIM To analyze the burden and trend of DHPM-CRC in the“B and R”countries from 1990 to 2019.METHODS We used the 2019 Global Burden of Disease Study to collate information regarding the burden of DHPM-CRC.Numbers and age-standardized rates(ASRs)of deaths along with the disability-adjusted life years(DALYs)were determined among the“B and R”countries in 1990 and 2019.Using joinpoint regression analysis,the average annual percent change(AAPC)was used to analyze the temporal trends of age-standardized DALYs rate(ASDALR)from 1990 to 2019 and in the final decade(2010–2019).RESULTS We found geographical differences in the burden of DHPM-CRC among“B and R”countries,with the three highest-ranking countries being the Russian Federation,China,and Ukraine in 1990,and China,the Russian Federation,and Poland in 2019.The burden of DHPM-CRC generally increased in most member countries from 1990 to 2019(all P<0.05).The absolute number of deaths and DALYs in DHPM-CRC were 3151.15[95%uncertainty interval(UI)665.74-5696.64]and 83249.31(95%UI 15628.64-151956.31)in China in 2019.However,the number of deaths(2627.57-2528.51)and DALYs(65867.39-55378.65)for DHPM-CRC in the Russian Federation has declined.The fastest increase in ASDALR for DHPM-CRC was observed in Vietnam,Southeast Asia,with an AAPC value of 3.90%[95%confidence interval(CI):3.63%-4.16%],whereas the fastest decline was observed in Kyrgyzstan,Central Asia,with an AAPC value of-2.05%(95%CI:-2.37%to-1.73%).A substantial upward trend in ASR of mortality,years lived with disability,years of life lost,and DALYs from DHPM-CRC changes in 1990-2019 and the final decade(2010-2019)for most Maritime Silk Route members in East Asia,South Asia,Southeast Asia,North Africa,and the Middle East,as well as Central Europe,while those of the most Land Silk Route members in Central Asia and Eastern Europe have decreased markedly(all P<0.05).The ASDALR for DHPM-CRC increased more in males than in females(all P<0.05).For those aged 50-74 years,the ASDALR for DHPM-CRC in 40 members exhibited an increasing trend,except for 20 members,including 7 members in Central Asia,Maldives,and 12 high or high-middle social development index(SDI)members in other regions(all P<0.05).CONCLUSION The burden of DHPM-CRC varies substantially across“B and R”countries and threatens public health.Relevant evidence-based policies and interventions tailored to the different trends of countries in SDIs or Silk Routes should be adopted to reduce the future burden of CRC in“B and R”countries via extensive collaboration.

基于Word2Vec和LDA主题模型的中国省级五年规划“文化政策”文本研究

运用Word2Vec和LDA相结合的主题模型分析技术,对我国31个省份三个时期五年规划文本中文化政策部分进行主题识别,从时间和空间两个维度进行“文化政策”主题挖掘和演化分析。研究发现,“文化政策”主题在发展趋势、重点转移、政策导向、技术应用等方面随时间推移呈现不同演化趋势;四大区域受经济发展水平、文化资源禀赋、政策导向影响,在企业角色强调程度、地区特色旅游发展以及国家级项目和竞争力方面存在地域差异。

Risk Factors for Geo-Helminthiasis in Children Aged 6 - 36 Months in a Rural Health District in Cameroon

Introduction and Objectives: Soil-Transmitted-Helminthiasis (STH) is a public health problem in Cameroon. The control strategies currently in place, particularly chemoprevention, has shortcomings linked to the target population, which are school-age children. The objective was to determine the prevalence and the risk factors associated with geo-helminthiasis in children aged 0 to 3 years in a rural health district. Method: From December 2020 to May 2021, a descriptive and analytical cross-sectional study of 376 children between 6 and 36 months was carried out in the Akonolinga health district. This was a cluster sampling in 4 health areas. Stool samples were collected and analysed using the mini-FLOTAC method. The results expressed as the number of eggs per gram of stool. A questionnaire on socio-demographic and lifestyle data was administered to the parents. The Chi-squared test was used to measure the association between geo-helminth infection and the data collected. A multivariate analysis using logistic regression was performed (p 0.05). Results: The prevalence of STH was 19.4% (Ascaris lumbricoides: 16% and Trichuris trichiura: 8%). Risk factors were: consumption of contaminated water (AOR = 1.93 [1.03 - 3.6];p = 0.040), early contact of the child with the ground (before age of 4 months) (AOR = 4.9 [2.1 - 11.37];p .001), habit of walking barefoot (AOR = 2.91 [1.1 - 7.97];p = 0.038), and living in a habitat with unpaved ground (AOR = 7.4 [1.55 - 35.7];p = 0.012). Conclusion: The prevalence of STHs in infants was high. Preventive chemotherapy should be extended to this age-group, and other measures intensified.

Review of Marxist Political Party Theory Innovation Over the 70 Years Since the Establishment of PRC

since the establishment of the People’s Republic of China,the central leader-groups from generation to generation have been continuously exploring and innovating Marxist political party theory in terms of its value target,ideological construction,working style,and organization developments.This process can be categorized into five stages:the founding stage in Mao Zedong’s era,the development stage in Deng Xiaoping’s ear,the promotion stage in Jiang Zemin’s times,the deepening stage under Hu Jintao’s leadership,and the stage of further innovation by Xi Jinping in the new era,with the characteristics of inheritance,development as well as scientificity and valuation.

Blason as a Means of Self-justification in John Ford’s ’Tis Pity She’s a Whore

The form of blason in John Ford's'Tis Pity She's a Whore provides a venue for its protagonist,Giovanni,not only to voice his socially-prohibited longings for incestuous love but also to normalise his amoral and murderous rhetoric.Changes in its contents and styles reflect the changes in its user's attitude towards social and cultural restrictions.The anachronism of the form of blason in the historical context of the play's performance also corresponds with Giovanni's refusal to comply with contemporary social and moral codes.His insistence on employing this mode of speech can be interpreted as a means of self-justification in his struggle between the external cultural norms and his internal call of nature.

The World's Largest Exhibition of Textile Machinery Goes to Italy in 2015 after 20 Years——MP International appointed to organize the show for the second time

Italy will host the 17th edition of ITMA, the world’s largest exhibition of textile machinery.It will be held at the Fiera Milano Rhoexhibition centre in Milan,from 12 to 19 November 2015.

Evolution of the “Zhejiang Spirit” During the Forty Years of Reform and Opening-up

The "Zhejiang spirit" refers to a theoretical summary of the group consciousness, mental state, value orientation and ideological realm, which is, as a motivating power, owned and recognized by all Zhejiang people, and carries Zhejiang peculiarities. President Xi Jinping, during his term of office in Zhejiang, launched a number of seminars and activities to seek "a Zhejiang spirit that moves with the times." Forty years of reform and opening-up, the "Zhejiang spirit" has experienced an evolution that can be summarized as three improvements: from spontaneous formation to deliberate cultivation, from something limited to eastern Zhejiang to an integrating force that spans the entire Zhejiang Province, and from a mere existence to a role that functions adequately. The "Zhejiang spirit" is extracted from the humanistic spirits shaped in all corners of Zhejiang province. It is "an instrumental ensemble played across the entire province," and represents a certain judgment and interpretation. The "Zhejiang spirit" not only describes and summarizes the past and present, but will also guide and motivate the future, and support people in their enterprising and industrious practices to move with the times.

Forest change of China in recent 300 years

Based on historical documents, modern survey and statistics, as well as the result of predecessor studies, the trend and main process of forest dynamics are recognized. The forest area and forest coverage rates for each province of China from 1700 to 1949 are estimated backward by every 50 years. Linking the result with modern National Forest Inventory data, the spatial-temporal dynamics of Chinese forest in recent 300 years （AD 1700-1998） is quantitatively analyzed. The study shows that in recent 300 years, the forest area in current territory of China has declined by 0.95×10^8 hm^2 （or 9.2% of the coverage rate） in total, with a trend of decrease and recovery. Before the 1960s, there was a trend of accelerated descending. The forest area was reduced by 1.66×10^8 hm^2 （or 17% of the coverage rate） in 260 years. While after the 1960s, there has been a rapid increase. The forest area increased by 0.7×10^8 hm^2 （or 8% of the coverage rate） in 40 years. The study also shows that there is a significant spatial difference in the dynamics of forest. The amplitudes of increasing and decreasing in western China are both smaller than the ones in eastern China. During the rapid declining period from 1700 to 1949, the most serious decrease appeared in the Northeast, the Southwest and the Southeast, where the coverage rate in most provinces dropped over 20%. In Heilongjiang Province, the coverage rate dropped by 50%. In Jilin Province, it dropped by 36%. In Sichuan Province and Chongqing Municipality, it dropped by 42%. In Yunnan Province, it dropped by 35%. During the recovery period 1949-1998, the western provinces, municipality and autonomous regions, including Ningxia, Gansu, Inner Mongolia, Sichuan-Chongqing, Yunnan, Tibet, Xinjiang and Qinghai, etc, the increase rates are all below 5%, while the eastern provinces, municipality and autonomous regions （except Heilongjiang, Hubei, Jiangsu-Shanghai） have achieved an increase over 5%, among which the Guangdong-Hainan, Guangxi, Anhui, Beijing-Tianjin-Hebei, Shandong, Henan, Zhejiang, and Fujian have an increase over 10%.

China’s “Education for All” Effort Fruitful in 30 Years

Of major events in China over the past three decades, most Chinese would list the resumption of National Examination for the Entrance of University as number one. In December 1977, 5.7 million Chinese participated in the national exams, the first since the catastrophic Cultural Revolution （1966-76）. One year later, the country＇s reform, opening up and modernization drive was launched.

Years of Concentrated Work Leads to Successive Glory——Ye Weimin,Vice President of ZTE,Talks About ZTE's Development Strategy on WCDMA

Editor’s Note:After becoming theleading force in CDMAequipment manufacturingin China, ZTE rolled outits self-developed WCD-MA products that at-tracted much expert at-tention in the MTNETsecond phase single sys- tem testing completed inJune 2003. Thefollowing are the remarks of Ye Weimin,ZTE’s vice president, on ZTE’s strate-gies, advantages and achievements inthe development of WCDMA products.

Cultivate Talent and Seek for Innovation in the past 20 Years——Exclusive Interview with Professor Li Chunling Dean of the School of Economics and Management, Yanshan University

Yanshan University was formerly known as Northeast Heavy Machinery Institute,and was one of the key universities in China at that time.As of1985,the institute moved to Qinhuangdao Island,and as it was located at the foot of Yanshan,it was called as Yanshan University.The School of Economics and Management was established in1979and the Management Engineering Department was established in1984,which was renamed as the School of Economics and Management in1998.This year is the20th anniversary for the establishment of the School.

A Review of Academic Divisions'Work over the Past Two Years

In line with the overall Objectives set out in the"Outline Scheme for the Academic Divisions of theChinese Academy of Sciences (CAS) during theNinth Five-year Plan (1996-2000)," CAS has donea good job of the supplementary election of CASmembers and the development of the virtues ofscience and fine style of research. In addihon, con-sultation and appraisal, academic exchanges, andthe popularization of science have progressivelybeen focuses of the academic divisions, and manyaccomplishments have been achieved in these areas.

Gorgeous Eight Years:SPINEXPO Moving into A New Journey Interview with Ms. Karine Van Tassel,the founder and organizer of SPINEXPO

Since the first International Textile Exhibition created by SPINEXPO in March 2003, Ms. Karine Van Tassel, the founder and organizer of SPINEXPO, dedicates herself to the display of the