Relationship among Health Related Quality of Life, Quality of Sleep, and Oral Health Condition

Japan’s aging rate (ratio of elderly aged 65 and older to total population) has exceeded 20%. The aim of this study was to clarify the relationships between Health Related Quality of Life, Body Mass Index (BMI), and sleep quality. Subjects were 51 adults over 55 years old with chronic disease who living in the community. Instruments and structured interviews were used giving due consideration to privacy. Interviews were conducted within 10 - 20 minutes at the out-patient department. The evaluation instruments included bodymass index, Pittsburgh Sleep Quality Index (PSQI), Health Related Quality of Life (HRQOL), and Oral Health Impact Profile (OHIP-14). A significant positive correlation (ρ = 0.321, p < 0.05) between PSQI and QOL (OHIP-14) scores was confirmed with sleep quality being lower with lower QOL scores. A negative correlation (ρ = ?0.339, p < 0.05) between physical health component summary scores (PCS) and mental health component summary scores (MCS) of HRQOL was confirmed, demonstrating that PCS was low, and the level of MCS was high. Sleep quality was found lower among those with lower oral health-related QOL scores. Moreover, in subjects with lower MCS scores, the PCS scores were found to be higher. Accordingly, it was considered appropriate that dental treatment and care, support the maintenance of activities and sleep, and mental health promotion which are likely requisites critical for elderly persons’ maintenance of independent lifestyles in their familiar community.

The effect of acculturation in the concordance of oral health related quality of life in Latino children and their parents

The Latino population is the fastest growing and the largest minority group in the United States comprising 16% of the population younger than 18 years of age. Yet, little is known about the effect of acculturation in oral health related quality of life in Latino children and their parents. Objective: The objective of this study was to assess the effect of acculturation in parent and child’s perceptions of the child’s oral health status and oral health related quality of life (OHRQoL) as well as the effect in the concordance between children and parents/caregivers. Method: Sixty-three Latino children between the ages of 8 and 15, and their parents were recruited from the waiting room at the University of California, San Francisco Orthodontic and Pediatric Clinics. Parent and children each separately completed the Child Oral Health Impact Profile questionnaire (COHIP) for children and COHIP for parent/caregiver. Results: Of the sixty-three children, fifteen children (23.8%) had a more negative perception of their oral health than their parents whereas twenty-three children (36.5%) had a more positive perception. In terms of agreement between children and parents, questions about oral health showed the lowest level of agreement (34.9%) and self-image questions the highest (55.6%). Conclusion: The study findings indicate that the more acculturated the child, the more negative their perception of their oral health. The level of disagreement between parent and child, underscores the importance of obtaining both the child and parent OHRQoL perceptions.

Oral health-related quality of life between Chinese and American orthodontic patients: A two-center cross-sectional study

Background:Although oral health-related quality of life(OHRQoL)in orthodontic patients has been assessed in the past,to date,no study has compared the OHRQoL between two nations.We aimed to compare the OHRQoL between Chinese and American orthodontic patients.Methods:We conducted a two-center questionnaire-based cross-sectional study among patients who underwent orthodontic treatments at the Chinese PLA General Hospital(PLAGH)in Beijing,China and Massachusetts General Hospital(MGH)in Boston,Massachusetts,United States.Candidate variables included the participating center,patients’age,sex,Angle’s classification of malocclusion,evaluation stage,and appliances used.The primary outcome was patients’OHRQoL assessed with the Oral Health Impact Profile-14(OHIP-14).Descriptive statistics,stratification,and univariate and multivariate analyses were performed.Results:The average age was lower for PLAGH patients than for MGH patients(21.1±7.9 vs.33.1±14.6 years,P<0.001).The most common type of malocclusion was Angle’s Class III malocclusion at PLAGH(39%)and Class I malocclusion at MGH(59.5%).Clear aligners were used in 34.1%and 2.7%of the patients at MGH and PLAGH,respectively.OHIP-14 scores were lower for PLAGH patients than for MGH patients(18.4±4.7 vs.22.3±7.4,P<0.001),particularly in functional limitation,psychological discomfort/disability,and handicap.Univariate regression analysis demonstrated that participating center,age,Class I malocclusion,and the use of clear aligners were significantly associated with overall OHIP-14 scores.Multivariate regression analysis demonstrated that patients at PLAGH were associated with lower OHIP-14 scores(coefficient:-3;95%CI:-5,-1.3;P=0.001),and age was positively associated with OHIP-14 scores(coefficient:0.1;95%CI:0.004,0.13;P=0.038).Conclusion:Chinese orthodontic patients had lower OHIP-14 scores,indicating a higher OHRQoL than American patients.In addition to the younger age,this difference may be attributed to the different ethical,cultural,educational,and socioeconomic background of Chinese and American orthodontic patients.

A Study on Oral Health-Related Quality of Life and Its Influencing Factors in Elderly Diabetic Patients

Objective:To investigate the oral health related quality of life in elderly diabetic patients and analyze its influencing factors.Methods:Convenience sampling was used to select 190 elderly patients with diabetes under the Department of Endocrinology and Department of Integrated Traditional Chinese and Western Medicine in the Affiliated Hospital of Hebei University as the research subjects.The Chinese version of the Oral Health Influence Scale(OHIP-14)was used to conduct a questionnaire survey,and univariate analysis and multiple stepwise regression analysis were used to analyze the influencing factors of oral health related quality of life in elderly diabetic patients.Results:The elderly diabetic patients'oral health related quality of life score was 34.48±3.23,which is in the middle-lower range.The findings of multivariate stepwise regression analysis revealed that the course of disease,regular visits to the dentist,sleep quality,oral health knowledge,and oral health attitude together explained 58.9%of the total variance in elderly diabetic patients in terms of their oral health related quality of life(p<0.05).Conclusion:The oral health related quality of life of elderly diabetic patients is generally low,and is affected by the duration of diabetes,sleep quality,and oral health knowledge,attitude,and behavior(regular visits to the dentist).Improving patientsJ attention to oral health problems by improving sleep as well as their own oral health knowledge,attitude,and behavior is an effective way to enhance oral health related quality of life.

Progress in Research of Oral Health in Patients with Type 2 Diabetes Quality of Life Impact

Multiple studies have demonstrated that oral health quality of life(OHQOL)in patients with type 2 diabetes(T2DM)is affected by multiple factors.Therefore,during this study the related factors of OHQOL for T2DM was reviewed,and analyzed them from the aspects of socio-demographic factors,T2DM related factors and oral health related factors.This was to provide basis for nursing workers to develop personalized nursing measures.

Effect of Malocclusion on Quality of Life among Persons Aged 7 - 25 Years: A Cross-Sectional Study

Background: The theory of Oral Health Related Quality Of Life (OHRQOL) has manifold qualities. It endeavors to address social and/or emotional concerns as well as any symptoms or functional problems related to the teeth and jaws from the patients view point. The difficulty of utilizing any one standard evaluation tool to determine how the patient feels about problems with malocclusions or arising from them, led to the development of this construct/theory. Aim: To evaluate the impact of malocclusion on the socio-functional and psychological wellbeing of persons 7 - 25 years old. Method: 100 patients within the ages of 7 - 25 years who visited the Orthodontics Unit of the Oral Health Directorate of Komfo Anokye Teaching Hospital (KATH), Kumasi, were conveniently sampled and surveyed. Participants were given questionnaires to assess the effects of malocclusion on their Oral Health Related Quality of Life and also to determine if their educational status had any influence on the impact of malocclusion on their oral health related quality of life. Results: The modal age of the participants was 10 - 15 years with 40% as it frequency followed by 7 - 9 years while the age with least frequency was 16 - 25 years which stood at 22.0%. 28 respondents reported negative effects on their functional domain. 71 of the participants reported negative effects on psychological well-being and 49 of them reported negative effects on social well-being. Conclusion: Malocclusion has an overall negative impact on Oral Health Related Quality of Life and its related purviews. It was observed to be highest for the psychological discomfort domain and the lowest in the functional well-being domain.

Impact of dental and orofacial trauma on oral health-related quality of life in adults:A systematic review

Purpose:Dental and orofacial trauma among the adult population constitutes a major public health problem.The impact is not just physical but also psychological.To analyse the impacts of dental and orofacial trauma on oral health-related quality of life(OHRQoL)in adults and determine whether the 2 variables are closely interlinked.Methods:This is a systematic review.The terms“dental trauma”,“orofacial trauma”,“oral health”,“oral health related impact life”,“OHRQoL”,“positive and negative affect scale”,“quality of life”,“facial injuries”,“adults”,and“young adults”were researched in the databases of PubMed,ScienceDirect,Scopus and Google Scholar for associated studies up to December 30,2022.A comprehensive search was designed and the articles were independently screened for eligibility by 2 reviewers.The included studies’author,year of publication,the country where the study was conducted,population demographics(number and age),an instrument used for assessing OHRQoL and the relevant result were recorded and compared.The quality of the evidence was assessed using Joanna Briggs Institute checklist for observational studies.Results:Out of 482 unique records,3 articles were included for data extraction.Observational studies were included.Two studies did not mention confounding factors.Different scales were used for dental and orofacial trauma and OHRQoL.OHRQoL has a directly proportional relationship with orofacial trauma.Adolescents with orofacial trauma have a significant impact on this value with a prevalence of 88.4%.Conclusion:The highest impact on OHRQoL was seen immediately after the diagnosis of an orofacial trauma.The impact increases with the severity of the trauma.Therefore,to promote overall dental and general health,health education initiatives should include information on the causes,prevention,and requirement for prompt responses by the populace in seeking dental intervention.

Patient-centric periodontal research:A pioneering application of patient-reported outcome measures

Conventional dentistry or periodontal research often ignores the human component in favor of clinical outcomes and biological causes.Clinical research is driven by the statistical significance of outcome parameters rather than the satisfaction level of the patient.In this context,patient-centric periodontal research(PCPR)is an approach that considers the patient´s feedback concerning their functional status,experience,clinical outcomes,and accessibility to their treatments.It is argued that data self-reported by the patient might have low reliability owing to the confounding effect of their personal belief,cultural background,and social and economic factors.However,literature has shown that the incorporation of“patient-centric outcome”components considerably enhances the validity and applicability of research findings.Variations in the results of different studies might be due to the use of different and non-standardized assessment tools.To overcome this problem,this editorial enlists various reliable tools available in the literature.In conclusion,we advocate that the focus of researchers should shift from mere periodontal research to PCPR so that the results can be effectively applied in clinical settings and the therapeutic strategy can also change from mere periodontal therapy to patient-centric periodontal therapy.

Evaluation of Oral Health-Related Quality of Life among Institutionalized Orphan Children

Introduction:Children residing in orphanages are a disadvantaged section of the population.Inadequate care can impair the quality of life of orphan children.Aim:The aim of this study was to assess the oral health-related quality of life and dental caries status among institutionalized orphan children.Materials and Methods:Children without parents,aged 6-14 years,were selected from government-run orphanages.Children who were willing to participate were included.Data on oral health-related quality of life were collected by personal interviews by a single investigator.Following,intraoral examination of each child was carried out in an adequate natural light using a sterilized mouth mirror and probe.Dental caries was assessed according to the World Health Organization criteria.The data obtained were subjected to statistical analysis.Results:The Decayed,Missed and Filled teeth(DMFT)score of males was 0.41士0.86 and females was 0.97士1.44,and the difference was statistically significant.The mean of oral symptoms,functional limitation,emotional well-being,and social well-being was 26.49±4.48,37.75士3.63,33.31±4.1&and 47.92士3.37,respectively.Conclusions:The prevalence of dental caries was low among these orphan children.The quality of life of these children was not affected by their dental caries status.

Italian Validation of the Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ)

The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) is a scale which measures aspects of the oral health-related quality of life. However, no Italian version of PIDAQ has been developed. The aim of this study was to translate the original English version of PIDAQ into Italian and to assess the validity and reliability of the Italian version for application among Italian adults. The questionnaire was translated into Italian, back translated, pre-tested, and cross-culturally adapted. Subsequently, the Italian version of PIDAQ and the Oral health impact Profile-14 (OHIP-14) were administered to 264 orthodontic patients aged from 18 to 83 years old, mean age was (38.39 + 16.9) belonging to Southern Italy. Cronbach’s alpha of the translated PIDAQ was 0.82, corrected item-total correlation ranged from 0.48 to 0.67. The 23 items of PIDAQ were divided into four domains. There was a logical relation among the items in the same domain and a highly significant association among scores of PIDAQ and the other scale. The translated Italian version of PIDAQ demonstrated good reliability and validity. Its sufficient discriminative and evaluative psycho-metric properties provide the theoretical evidence for further use in study on orthodontic-specific aspects of quality of life among Italian adults.

Artificial intelligence in dentistry:Harnessing big data to predict oral cancer survival

BACKGROUND Oral cancer is the sixth most prevalent cancer worldwide.Public knowledge in oral cancer risk factors and survival is limited.AIM To come up with machine learning(ML)algorithms to predict the length of survival for individuals diagnosed with oral cancer,and to explore the most important factors that were responsible for shortening or lengthening oral cancer survival.METHODS We used the Surveillance,Epidemiology,and End Results database from the years 1975 to 2016 that consisted of a total of 257880 cases and 94 variables.Four ML techniques in the area of artificial intelligence were applied for model training and validation.Model accuracy was evaluated using mean absolute error(MAE),mean squared error(MSE),root mean squared error(RMSE),R2 and adjusted R2.RESULTS The most important factors predictive of oral cancer survival time were age at diagnosis,primary cancer site,tumor size and year of diagnosis.Year of diagnosis referred to the year when the tumor was first diagnosed,implying that individuals with tumors that were diagnosed in the modern era tend to have longer survival than those diagnosed in the past.The extreme gradient boosting ML algorithms showed the best performance,with the MAE equaled to 13.55,MSE 486.55 and RMSE 22.06.CONCLUSION Using artificial intelligence,we developed a tool that can be used for oral cancer survival prediction and for medical-decision making.The finding relating to the year of diagnosis represented an important new discovery in the literature.The results of this study have implications for cancer prevention and education for the public.

Risks Factors of Caries and Periodontal Diseases in the Patients, after 5 Years Use a Partial Removable Denture

Objective: The goal of the removable partial denture is to restore impaired esthetics and masticatory function by replacing missing teeth. The aim of this study was to establish a possible correla-tion between removable partial denture in acrylic resin use after 5 years and dental diseases. Materials and Methods: Partially edentulous patients presenting for removable denture treatment at the Prosthodontics service of the Affiliated Hospital of Kinshasa University, Democratic Republic of Congo were assessed in this study. Patients were randomly assigned into 2 groups: Denture and non-denture group. Caries and periodontal diseases were compared between both groups. Statistical significance was set at p < 0.05. Results: The average age in the denture and non-denture-group was 53.15 (±SD 22.05) and 31.59 (±SD 11.98) years. Out of 160 teeth were decayed, both 110 teeth (68.75%) in the denture-group and 50 teeth (31.25%) in the non-denture group. The DMFT index calculated at start time of the study was 0.2 for both groups, after five years was 7.1 for the denture-group and 2.6 for the non-denture-group. The plaque index in the denture-group had an index of 1 and that of non-denture-group was 0.5. Conclusion: The relationship has been found between patients’ wearers a RPD and dental diseases.

慢性牙髓炎患者血清炎症递质水平与口腔健康相关生活质量的关系

目的 分析慢性牙髓炎患者血清炎症递质水平与口腔健康相关生活质量的关系。方法 将116例慢性牙髓炎患者设为研究组,另选取同期健康体检者116名设为对照组。比较两组被试者血清炎症递质[白介素-1β(IL-1β)、白介素-6(IL-6)、白介素-8(IL-8)、白介素-17(IL-17)、肿瘤坏死因子-α(TNF-α)、C反应蛋白(CRP)、前列腺素E2(PGE2)、P物质(SP)]水平与口腔健康影响程度量表中文版(OHIP-14)评分,采用Pearson相关系数评估慢性牙髓炎患者血清炎症递质水平与OHIP-14评分的相关性。结果 研究组患者血清IL-1β、IL-6、IL-8、IL-17、TNF-α、CRP、PGE2、SP水平,OHIP-14总分及各领域评分均高于对照组(P<0.01)。研究组患者血清IL-1β、IL-6、IL-8、IL-17、TNF-α、CRP、PGE2、SP水平与OHIP-14总分均呈正相关(r=0.659、0.623、0.678、0.611、0.697、0.683、0.725、0.713,P<0.01)。结论 慢性牙髓炎患者血清炎症递质水平较高,明显影响患者生活质量与心身健康,临床实践中要给予适当干预。

牙周内窥镜辅助龈下刮治和根面平整术的临床疗效及对牙周炎患者心理与生活质量的影响

目的探讨牙周内窥镜(periodontal endoscope,PE)辅助龈下刮治和根面平整术(scaling and root plan⁃ning,SRP)的临床疗效及对牙周炎患者心理和生活质量的影响,为临床应用牙周内窥镜提供参考。方法本研究已通过单位伦理委员会审查批准,并获得患者知情同意。收集2018年4月—2022年12月于南京大学医学院附属口腔医院牙周病科就诊的,传统SRP治疗6周后复查仍有残留牙周袋探诊深度(probing depth,PD)≥5 mm的牙周炎患者,进一步行PE辅助SRP(PE+SRP)。在传统SRP治疗后6周,PE+SRP治疗3个月后分别测量牙周临床指标包括菌斑指数(plaque index,PLI)、PD、临床附着丧失(clinical attachment loss,CAL)及探诊出血(bleeding on probing,BOP);同时分别收集传统SRP和PE辅助SRP治疗即刻视觉模拟评分量表(visual analogue scale,VAS);在传统SRP治疗和PE辅助SRP治疗3个月后分别收集牙周组织自我认知表、口腔健康影响程度量表⁃14(oral health impact profile⁃14,OHIP⁃14)以及牙科畏惧调查量表(dental fear scale,DFS)。结果共纳入牙周炎患者23例,患牙486颗,832个位点纳入临床研究。PE+SRP治疗后3个月,各项牙周临床指标:PLI(t=9.254,P<0.001)、PD(t=50.724,P<0.001)、CAL(t=22.407,P<0.001)以及BOP(t=9.217,P<0.001)均显著改善;与传统SRP(VAS:2.48±1.70)相比,PE+SRP(VAS:2.57±1.80)给患者带来的疼痛感无显著差异(t=0.192,P=0.850);两组牙周组织自我认知表得分无显著性差异(t=1.485,P=0.152);同时传统SRP完成后OHIP⁃14的得分为(12.13±7.63)分,PE+SRP完成后OHIP⁃14得分为(10.26±5.25)分,两者无显著差异(t=-1.589,P=0.126);传统SRP完成后DFS量表得分为(40.70±12.63)分,PE+SRP完成后DFS量表得分为(41.57±12.61)分,两者无显著差异(t=0.404,P=0.690)。结论PE辅助SRP治疗牙周炎患者残留牙周袋后各项牙周临床指标均显著改善,且与传统SRP相比,PE辅助SRP对牙周炎患者的生活质量和心理状况没有负面影响,可以临床广泛推广。

比较无托槽隐形和固定矫治对青少年患者生活质量的影响

目的研究行无托槽隐形矫治器与固定矫治器青少年正畸患者的治疗体验和生活质量差异。方法选取2022年1月—6月在南京医科大学附属口腔医院使用无托槽隐形矫治器或固定矫治器的104例青少年作为研究对象,按照矫治器种类分为2个治疗组,各52例。青少年正畸患者在使用无托槽隐形矫治器或固定矫治器6个月内,调查青少年口腔健康影响简表19(COHIP⁃SF 19),以及其他单独项目。采用独立样本t检验比较平均满意度、生活质量和领域得分的差异,采用Wilcoxon秩和检验比较主观响应的差异。结果两组之间的平均生活质量及领域得分基本没有显著性差异,隐形矫治的患者具有更高的满意度。隐形矫治组报告进食困难的影响更大,固定矫治器患者易产生更大的负面情绪。此外,在矫治器适应时间、保持牙齿清洁以及觉得自己很有魅力方面两组间无显著差异。结论两组患者对治疗方式总体满意。接受无托槽隐形矫治器与固定矫治器治疗至少6个月的青少年正畸患者的总体生活质量相似。

多元化健康教育对牙周加速成骨正畸手术患者生活质量及焦虑的影响

目的探究在牙周加速成骨正畸(periodontally accelerated osteogenic orthodontics,PAOO)术后应用多元化健康教育对患者生活质量及焦虑的影响效果,为探索更好的健康教育模式提供临床依据。方法选择2022年4月至2023年12月期间在昆明医科大学附属口腔医院正畸科就诊且需要做PAOO手术的患者作为研究对象,通过随机分配法分为对照组和观察组,各纳入42例。对照组只接受标准的常规健康教育,包括术前口头宣教、术中沟通和术后指导。实验组患者则在常规健康教育的基础上建立多元化健康宣教小组,在围手术期进行一对一指导。在术前及术后对2组患者的焦虑(SAS、MDAS)、疼痛(VAS)、术后临床表现(如出血、恶心程度、睡眠等)、口腔健康自我管理效能(SESS)、口腔内菌斑指数(PLI)进行评估和比较。在PAOO术前术后对两组患者的焦虑、恐惧、疼痛、生活质量以及口腔健康自我管理能力进行评估比较。结果观察组患者在术后3天SAS评分显著低于对照组,MDAS评分显著降低(P<0.001)。术后7 d VAS评分显示,观察组较对照组显著降低(P<0.001)。观察组患者术后出血和恶心程度显著低于对照组(P<0.001)。此外,观察组的口腔健康自我效能在术后1个月显著提升(P<0.001),菌斑指数显著下降(P<0.05),在生活质量方面,观察组在术后1个月的总体生活质量评分显著高于对照组(P<0.001)。结论在PAOO围手术期的护理工作中,结合多元化健康教育措施能够有效减轻患者的不适,缓解其焦虑,提升患者围手术期生活质量以及口腔健康自我管理能力。

528例老年人口腔健康生活质量状况调查及影响因素分析

目的 调查528例老年人口腔健康生活质量的状况,分析影响老年人口腔健康生活质量的因素,为开展老年人口腔健康宣教活动提供参考。方法 选择2022年5月至2023年5月528例老年人作为研究对象,采用口腔健康评价指数量表(geriatric oral health assessment index, GOHAI)调查老年人口腔健康生活质量的状况,根据GOHAI量表评分将社区老人分为对照组(GOHAI≤24分)和观察组(GOHAI> 24分)。采用Logistic多元回归模型分析老年人口腔健康生活质量的影响因素。结果 528例社区老年人中,口腔健康生活质量差的381例,占比72.16%;口腔健康生活质量良好的社区老年人147例,占比27.84%;观察组与对照组社区老年人在文化程度、吸烟、饮酒、刷牙频率、是否口腔疾病、天然牙数量、义齿情况、是否接受口腔健康教育、就医是否方便等差异有统计学意义(P <0.05);文化程度低、吸烟、饮酒、刷牙频率<2次/天、口腔疾病、天然牙数量<15个、义齿、未接受口腔健康教育及就医不方便是影响老年人口腔健康生活质量的影响因素(P <0.05)。结论 社区老年人口腔健康受文化程度、吸烟、饮酒、刷牙频率、口腔疾病等多重因素影响,社区应积极开展口腔健康宣教活动,促进老年人口腔保健意识,提高晚年生活质量。

多感官叠加教育对慢性牙周炎病人牙周指标及口腔健康素养的影响

目的:探讨多感官叠加教育对慢性牙周炎病人牙周指标及口腔健康素养的影响。方法:选取2021年7月—2023年7月南京医科大学附属口腔医院口腔科收治的120例慢性牙周炎病人为研究对象,随机分为两组,各60例。对照组实施常规护理,观察组在常规护理基础上实施多感官叠加教育,比较两组牙周指标、口腔健康素养及生活质量。结果:实施多感官叠加教育干预后,观察组牙龈指数、牙菌斑指数、牙结石指数、牙周袋深度低于对照组,口腔健康素养评分高于对照组,生活质量评分低于对照组,两组比较差异均有统计学意义(P<0.001)。结论:多感官叠加教育有助于提高病人牙周指标,提升病人口腔健康素养,提高生活质量。

牙髓炎患者炎症介质与疼痛、口腔健康、生存质量的关系

目的研究牙髓炎患者炎症介质水平变化及其与根管治疗术后疼痛、口腔健康、生存质量的关系。方法以2021年1月-2022年12月南京市江宁医院收治的牙髓炎患者104例为观察组,所有患者均采用根管治疗术治疗,术后观察1个月;选取同期在该院接受正畸牙拔除治疗的健康受试者112例为对照组,比较2组血清和龈沟液中炎症介质水平及观察组治疗前后疼痛、口腔健康、生存质量评分,分析牙髓炎患者炎症介质水平变化与根管治疗术后疼痛、口腔健康、生存质量评分的关系。结果观察组治疗前及治疗1个月后血清、龈沟液基质金属蛋白酶-8(MMP-8)、白介素-8(IL-8)、白介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)水平均高于对照组治疗前(P<0.05);观察组治疗1个月后血清、龈沟液MMP-8、IL-8、IL-6、TNF-α水平低于治疗前(P<0.05);观察组治疗后1个月疼痛、口腔健康评分较治疗前降低,社会功能、咀嚼功能、物质生活、心理功能评分较治疗前升高(P<0.05);Pearson相关分析结果显示,观察组血清、龈沟液MMP-8、IL-8、IL-6、TNF-α水平变化与根管治疗术后疼痛、口腔健康评分均呈显著正相关,与社会功能、咀嚼功能、物质生活、心理功能评分呈显著负相关。结论牙髓炎的发生可引起患者血清和龈沟液中炎症介质水平升高,其水平变化与患者根管治疗术后疼痛、口腔健康、生存质量具有显著相关性。

无托槽隐形矫治器与固定矫治器对青少年非拔牙正畸患者牙周健康及生活质量的影响比较

目的:分析无托槽隐形矫治器与固定矫治器的临床疗效及对青少年正畸患者牙周健康及口腔健康相关生活质量的影响。方法:将2019—2021年在郑州大学第一附属医院惠济院区进行正畸治疗的80例青少年正畸患者随机分为隐形组(n=40)和固定组(n=40),分别接受无托槽隐形矫治器与固定矫治器正畸治疗。比较两组患者的牙周健康、口腔健康生活质量及并发症发生情况发症发生情况。结果:治疗前及治疗6个月,两组患者的牙周健康指标差异无统计学意义(P>0.05);但治疗12个月,隐形组牙周健康指标-菌斑指数评分显著低于固定组(P<0.05)。治疗前两组患者的口腔健康影响程度量表各维度评分及总分差异无统计学意义(P>0.05),治疗12个月,隐形组的口腔健康、社会-情感健康及COHIP总分均高于固定组(P<0.05)。隐形组的并发症总发生率为30.00%,显著低于固定组的52.50%(P<0.05)。结论:矫治12个月后,无托槽隐形矫治器与固定矫治器治疗青少年正畸患者的疗效相当,但无托槽隐形矫治器在维护牙周健康、提升生活质量和减少并发症上具有优势。