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Fluidization and Transport of Vibrated Granular Matter:A Review of Landmark and Recent Contributions 被引量:1
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作者 Peter Watson Sebastien Vincent Bonnieu Marcello Lappa 《Fluid Dynamics & Materials Processing》 EI 2024年第1期1-29,共29页
We present a short retrospective review of the existing literature about the dynamics of(dry)granular matter under the effect of vibrations.The main objective is the development of an integrated resource where vital i... We present a short retrospective review of the existing literature about the dynamics of(dry)granular matter under the effect of vibrations.The main objective is the development of an integrated resource where vital information about past findings and recent discoveries is provided in a single treatment.Special attention is paid to those works where successful synthetic routes to as-yet unknown phenomena were identified.Such landmark results are analyzed,while smoothly blending them with a history of the field and introducing possible categorizations of the prevalent dynamics.Although no classification is perfect,and it is hard to distillate general properties out of specific observations or realizations,two possible ways to interpret the existing results are defined according to the type of forcing or the emerging(ensuing)regime of motion.In particular,first results concerning the case where vibrations and gravity are concurrent(vertical shaking)are examined,then the companion situation with vibrations perpendicular to gravity(horizontal shaking)is described.Universality classes are introduced as follows:(1)Regimes where sand self-organizes leading to highly regular geometrical“pulsating”patterns(thin layer case);(2)Regimes where the material undergoes“fluidization”and develops an internal multicellular convective state(tick layers case);(3)Regimes where the free interface separating the sand from the overlying gas changes inclination or develops a kind a patterned configuration consisting of stable valleys and mountains or travelling waves;(4)Regimes where segregation is produced,i.e.,particles of a given size tend to be separated from the other grains(deep containers).Where possible,an analogy or parallelism is drawn with respect to the companion field of fluid-dynamics for which the assumption of“continuum”can be applied. 展开更多
关键词 granular materials vibrations FLUIDIZATION FLOWABILITY symmetry breaking
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Multi-layer perceptron-based data-driven multiscale modelling of granular materials with a novel Frobenius norm-based internal variable 被引量:1
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作者 Mengqi Wang Y.T.Feng +1 位作者 Shaoheng Guan Tongming Qu 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2198-2218,共21页
One objective of developing machine learning(ML)-based material models is to integrate them with well-established numerical methods to solve boundary value problems(BVPs).In the family of ML models,recurrent neural ne... One objective of developing machine learning(ML)-based material models is to integrate them with well-established numerical methods to solve boundary value problems(BVPs).In the family of ML models,recurrent neural networks(RNNs)have been extensively applied to capture history-dependent constitutive responses of granular materials,but these multiple-step-based neural networks are neither sufficiently efficient nor aligned with the standard finite element method(FEM).Single-step-based neural networks like the multi-layer perceptron(MLP)are an alternative to bypass the above issues but have to introduce some internal variables to encode complex loading histories.In this work,one novel Frobenius norm-based internal variable,together with the Fourier layer and residual architectureenhanced MLP model,is crafted to replicate the history-dependent constitutive features of representative volume element(RVE)for granular materials.The obtained ML models are then seamlessly embedded into the FEM to solve the BVP of a biaxial compression case and a rigid strip footing case.The obtained solutions are comparable to results from the FEM-DEM multiscale modelling but achieve significantly improved efficiency.The results demonstrate the applicability of the proposed internal variable in enabling MLP to capture highly nonlinear constitutive responses of granular materials. 展开更多
关键词 granular materials History-dependence Multi-layer perceptron(MLP) Discrete element method FEM-DEM Machine learning
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An inverse analysis of fluid flow through granular media using differentiable lattice Boltzmann method 被引量:1
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作者 Qiuyu Wang Krishna Kumar 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第6期2077-2090,共14页
This study presents a method for the inverse analysis of fluid flow problems.The focus is put on accurately determining boundary conditions and characterizing the physical properties of granular media,such as permeabi... This study presents a method for the inverse analysis of fluid flow problems.The focus is put on accurately determining boundary conditions and characterizing the physical properties of granular media,such as permeability,and fluid components,like viscosity.The primary aim is to deduce either constant pressure head or pressure profiles,given the known velocity field at a steady-state flow through a conduit containing obstacles,including walls,spheres,and grains.The lattice Boltzmann method(LBM)combined with automatic differentiation(AD)(AD-LBM)is employed,with the help of the GPU-capable Taichi programming language.A lightweight tape is used to generate gradients for the entire LBM simulation,enabling end-to-end backpropagation.Our AD-LBM approach accurately estimates the boundary conditions for complex flow paths in porous media,leading to observed steady-state velocity fields and deriving macro-scale permeability and fluid viscosity.The method demonstrates significant advantages in terms of prediction accuracy and computational efficiency,making it a powerful tool for solving inverse fluid flow problems in various applications. 展开更多
关键词 Inverse problem Fluid flow granular media Automatic differentiation(AD) Lattice Boltzmann method(LBM)
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Mobility and dynamic erosion process of granular flow:insights from numerical investigation using material point method
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作者 YU Fangwei SU Lijun +1 位作者 LI Xinpo ZHAO Yu 《Journal of Mountain Science》 SCIE CSCD 2024年第8期2713-2738,共26页
In order to understand the dynamics of granular flow on an erodible base soil,in this paper,a series of material point method-based granular column collapse tests were conducted to investigate numerically the mobility... In order to understand the dynamics of granular flow on an erodible base soil,in this paper,a series of material point method-based granular column collapse tests were conducted to investigate numerically the mobility and dynamic erosion process of granular flow subjected to the complex settings,i.e.,the aspect ratio,granular mass,friction and dilatancy resistance,gravity and presence of water.A set of power scaling laws were proposed to describe the final deposit characteristics of granular flow by the relations of the normalized run-out distance and the normalized final height of granular flow against the aspect ratio,being greatly affected by the complex geological settings,e.g.,granular mass,the friction and dilatancy resistance of granular soil,and presence of water in granular flow.An index of the coefficient of friction of granular soil was defined as a ratio of the target coefficient of friction over the initial coefficient of friction to quantify the scaling extent of friction change(i.e.,friction strengthening or weakening).There is a characteristic aspect ratio of granular column corresponding to the maximum mobility of granular flow with the minimum index of the apparent coefficient of friction.The index of the repose coefficient of friction of granular flow decreased gradually with the increase in aspect ratio because higher potential energy of granular column at a larger aspect ratio causes a larger kinetic energy of granular soil to weaken the friction of granular soil as a kind of velocity-related friction weakening.An increase in granular mass reduces gradually the indexes of the apparent and repose coefficients of friction of granular soil to enhance the mobility of granular flow.The mobility of granular flow increases gradually with the decrease in friction angle or increase in dilatancy angle of granular soil.However,the increase of gravity accelerates granular flow but showing the same final deposit profile without any dependence on gravity.The mobility of granular flow increases gradually by lowering the indexes of the apparent and repose coefficients of friction of granular flow while changing the surroundings,in turn,the dry soil,submerged soil and saturated soil,implying a gradually increased excessive mobility of granular flow with the friction weakening of granular soil.Presence of water in granular flow may be a potential catalyzer to yield a long run-out granular flow,as revealed in comparison of water-absent and water-present granular flows.In addition,the dynamic erosion and entrainment of based soil induced by granular flow subjected to the complex geological settings,i.e.,the aspect ratio,granular mass,gravity,friction and dilatancy resistance,and presence of water,were comprehensively investigated as well. 展开更多
关键词 Column collapse granular flow granular soil Material point method MOBILITY Numerical tests
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Alternative Method of Constructing Granular Neural Networks
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作者 Yushan Yin Witold Pedrycz Zhiwu Li 《Computers, Materials & Continua》 SCIE EI 2024年第4期623-650,共28页
Utilizing granular computing to enhance artificial neural network architecture, a newtype of network emerges—thegranular neural network (GNN). GNNs offer distinct advantages over their traditional counterparts: The a... Utilizing granular computing to enhance artificial neural network architecture, a newtype of network emerges—thegranular neural network (GNN). GNNs offer distinct advantages over their traditional counterparts: The ability toprocess both numerical and granular data, leading to improved interpretability. This paper proposes a novel designmethod for constructing GNNs, drawing inspiration from existing interval-valued neural networks built uponNNNs. However, unlike the proposed algorithm in this work, which employs interval values or triangular fuzzynumbers for connections, existing methods rely on a pre-defined numerical network. This new method utilizesa uniform distribution of information granularity to granulate connections with unknown parameters, resultingin independent GNN structures. To quantify the granularity output of the network, the product of two commonperformance indices is adopted: The coverage of numerical data and the specificity of information granules.Optimizing this combined performance index helps determine the optimal parameters for the network. Finally,the paper presents the complete model construction and validates its feasibility through experiments on datasetsfrom the UCIMachine Learning Repository. The results demonstrate the proposed algorithm’s effectiveness andpromising performance. 展开更多
关键词 granular neural network granular connection interval analysis triangular fuzzy numbers particle swarm optimization(PSO)
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A pressure-sensitive rheological origin of high friction angles of granular matter observed in NASA–MGM project
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作者 程晓辉 肖世泽 +2 位作者 杨森 赵乃峰 Alex Sixie Cao 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第6期559-567,共9页
An abnormally high peak friction angle of Ottawa sand was observed in(National Aeronautics and Space Administration) NASA–(Mechanics of Granular Materials) MGM tests in microgravity conditions on the space shuttle. P... An abnormally high peak friction angle of Ottawa sand was observed in(National Aeronautics and Space Administration) NASA–(Mechanics of Granular Materials) MGM tests in microgravity conditions on the space shuttle. Previous investigations have been unsuccessful in providing a constitutive insight into this behavior of granular materials under extremely low effective stress conditions. Here, a recently proposed unified constitutive model for transient rheological behavior of sand and other granular materials is adopted for the analytical assessment of high peak friction angles. For the first time, this long-eluded behavior of sand is attributed to a hidden rheological transition mechanism, that is not only rate-sensitive, but also pressure-sensitive. The NASA–MGM microgravity conditions show that shear-tests of sand can be performed under abnormally low confining stress conditions. The pressure-sensitive behavior of granular shearing that is previously ignored is studied based on the μ(I) rheology and its variations. Comparisons between the model and the NASA microgravity tests demonstrate a high degree of agreement. The research is highly valid for pressure-sensitive and rate-dependent problems that occur during earthquakes, landslides, and space exploration. 展开更多
关键词 granular matter MICROGRAVITY pressure-sensitive NASA–MGM
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Effect of granular shape on radial segregation in a two-dimensional drum
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作者 徐悦 李然 +3 位作者 迟志鹏 修文正 孙其诚 杨晖 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期509-514,共6页
Granular segregation is widely observed in nature and industry.Most research has focused on segregation caused by differences in the size and density of spherical grains.However,due to the fact that grains typically h... Granular segregation is widely observed in nature and industry.Most research has focused on segregation caused by differences in the size and density of spherical grains.However,due to the fact that grains typically have different shapes,the focus is shifting towards shape segregation.In this study,experiments are conducted by mixing cubic and spherical grains.The results indicate that spherical grains gather at the center and cubic grains are distributed around them,and the degree of segregation is low.Through experiments,a structured analysis of local regions is conducted to explain the inability to form stable segregation patterns with obviously different geometric shapes.Further,through simulations,the reasons for the central and peripheral distributions are explained by comparing velocities and the number of collisions of the grains in the flow layer. 展开更多
关键词 granular materials cubic grains shape segregation segregation mechanism
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Filtration performance and modeling of granular bed for dust removal from coal pyrolytic vapors
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作者 Shuaiqiang Yang Lin Du +3 位作者 Guangchao Ding Runguo Liu Wenli Song Songgeng Li 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第1期35-42,共8页
Dust removal from pyrolytic vapors at high temperatures is an obstacle to the industrialization of the coal pyrolysis process.In this work,a granular bed with expanded perlites as filtration media was designed and int... Dust removal from pyrolytic vapors at high temperatures is an obstacle to the industrialization of the coal pyrolysis process.In this work,a granular bed with expanded perlites as filtration media was designed and integrated into a 10 t·d^(–1)coal pyrolysis facility.The testing results showed that around 97.56%dust collection efficiency was achieved.As a result,dust content in tar was significantly lowered.The pressure drop of the granular bed maintained in the range of 356 Pa to 489 Pa.The dust size in the effluent after filtration exhibited a bimodal distribution,which was attributed to the heterogeneity of the dust components.The effects of filtration bed on pyrolytic product yields were also discussed.A modified filtration model based on the macroscopic phenomenological theory was proposed to describe the performance of the granular bed.The computation results were well agreed with the experimental data. 展开更多
关键词 granular bed filtration Dust removal PYROLYSIS FILTRATION FIXED-BED
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Finite Element Simulations on Failure Behaviors of Granular Materials with Microstructures Using a Micromechanics-Based Cosserat Elastoplastic Model
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作者 Chenxi Xiu Xihua Chu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第3期2305-2338,共34页
This paper presents a micromechanics-based Cosserat continuum model for microstructured granular materials.By utilizing this model,the macroscopic constitutive parameters of granular materials with different microstru... This paper presents a micromechanics-based Cosserat continuum model for microstructured granular materials.By utilizing this model,the macroscopic constitutive parameters of granular materials with different microstructures are expressed as sums of microstructural information.The microstructures under consideration can be classified into three categories:a medium-dense microstructure,a dense microstructure consisting of one-sized particles,and a dense microstructure consisting of two-sized particles.Subsequently,the Cosserat elastoplastic model,along with its finite element formulation,is derived using the extended Drucker-Prager yield criteria.To investigate failure behaviors,numerical simulations of granular materials with different microstructures are conducted using the ABAQUS User Element(UEL)interface.It demonstrates the capacity of the proposed model to simulate the phenomena of strain-softening and strain localization.The study investigates the influence of microscopic parameters,including contact stiffness parameters and characteristic length,on the failure behaviors of granularmaterials withmicrostructures.Additionally,the study examines themesh independence of the presented model and establishes its relationship with the characteristic length.A comparison is made between finite element simulations and discrete element simulations for a medium-dense microstructure,revealing a good agreement in results during the elastic stage.Somemacroscopic parameters describing plasticity are shown to be partially related to microscopic factors such as confining pressure and size of the representative volume element. 展开更多
关键词 granular materials MICROMECHANICS Cosserat elastoplastic model MICROSTRUCTURES failure behaviors
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Response of the Maize Variety EV87-28 to a Fertilization Strategy Involving Indorama Granular Urea on Ferralsol in the Central Ivory Coast
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作者 Fernand Guy Yao Kouadio Amani +6 位作者 Brou Kouame Jean Lopez Essehi Brahima Kone Kouadio Houphouet Cheikh Ahmed Diawara Bala Mamadou Ouattara Albert Yao-Kouame 《Agricultural Sciences》 2024年第1期187-208,共22页
In Côte d’Ivoire, the decline in soil fertility strongly impacts the productivity of maize (Zea mays L.) on heavily leached ferralitic soil. In this study, the general objective was therefore to improve the prod... In Côte d’Ivoire, the decline in soil fertility strongly impacts the productivity of maize (Zea mays L.) on heavily leached ferralitic soil. In this study, the general objective was therefore to improve the productivity of maize EV87-28 on the Ferralsols in pre-forested areas during different cropping seasons. Eight (8) micro-plots were set up according to a total randomization device with three repetitions. Two factors were studied: nitrogen fertilizer modalities (main factor) and crop season (secondary factor). Growth, flowering and yield parameters were measured and analyzed. The results showed that there was no interaction between the nitrogen fertilizer factor and the cropping season factor. In addition, this study showed the short rainy season had the most positive impact on growth, flowering and yield parameters than the long rainy season. The results also showed that the different nitrogen fertilizer modalities had no statistically different effects on growth, flowering and yield parameters. However, quantitative differences were reported, highlighting one nitrogen fertilizer modality, which is the combination of urea granule + farm manure (75% urea indorama granules and 25% farm manure). The combination of urea granule + farm manure (75% urea indorama granules and 25% farm manure) had the best effect on corn grain yield. So, the combination of urea (75%) and manure (25%), that resulted in yield gain, could be recommended for corn fertilization during the small rainy season. 展开更多
关键词 Indorama granular Urea FERRALSOL Cultural Seasons MAIZE Ivory Coast
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A thermodynamics-based three-scale constitutive model for partially saturated granular materials
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作者 Jianqiu Tian Enlong Liu Yuancheng Guo 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第5期1813-1831,共19页
A three-scale constitutive model for unsaturated granular materials based on thermodynamic theory is presented.The three-scale yield locus,derived from the explicit yield criterion for solid matrix,is developed from a... A three-scale constitutive model for unsaturated granular materials based on thermodynamic theory is presented.The three-scale yield locus,derived from the explicit yield criterion for solid matrix,is developed from a series of discrete interparticle contact planes.The three-scale yield locus is sensitive to porosity changes;therefore,it is reinterpreted as a corresponding constitutive model without phenomenological parameters.Furthermore,a water retention curve is proposed based on special pore morphology and experimental observations.The features of the partially saturated granular materials are well captured by the model.Under wetting and isotropic compression,volumetric compaction occurs,and the degree of saturation increases.Moreover,the higher the matric suction,the greater the strength,and the smaller the volumetric compaction.Compared with the phenomenological Barcelona basic model,the proposed three-scale constitutive model has fewer parameters;virtually all parameters have clear physical meanings. 展开更多
关键词 Unsaturated granular material Unsaturated porous material GEOMATERIALS Multi-scale constitutive model Water retention curve PLASTICITY
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Evaluation of the coefficient of lateral stress at rest of granular materials under repetitive loading conditions
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作者 Heerym Han Hyunwook Choo Junghee Park 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第5期1709-1721,共13页
Although the internal stress state of soils can be affected by repetitive loading,there are few studies evaluating the lateral stress(or K_(0))of soils under repetitive loading.This study investigates the changes in K... Although the internal stress state of soils can be affected by repetitive loading,there are few studies evaluating the lateral stress(or K_(0))of soils under repetitive loading.This study investigates the changes in K_(0) and directional shear wave velocity(V_(s))in samples of two granular materials with different particle shapes during repetitive loading.A modified oedometer cell equipped with bender elements and a diaphragm transducer was developed to measure the variations in the lateral stress and the shear wave velocity,under repetitive loading on the loading and unloading paths.The study produced the following results:(1)Repetitive loading on the loading path resulted in an increase in the K_(0) of test samples as a function of cyclic loading number(i),and(2)Repetitive loading on the unloading path resulted in a decrease in K_(0) according to i.The shear wave velocity ratio(i.e.V_(s)(HH)/V_(s)(VH),where the first and second letters in parentheses corresponds to the directions of wave propagation and particle motion,respectively,and V and H corresponds to the vertical and horizontal directions,respectively)according to i supports the experimental observations of this study.However,when the tested material was in lightly over-consolidated state,there was an increase in K_(0) during repetitive loading,indicating that it was the initial K_(0),rather than the loading path,which is responsible for the change in K_(0).The power model can capture the variation in the K_(0) of samples according to i.Notably,the K_(0)=1 line acts as the boundary between the increase and decrease in K_(0) under repetitive loading. 展开更多
关键词 Coefficient of lateral stress at rest Repetitive loading granular materials Shear wave velocity Stiffness anisotropy
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Numerical investigation of the effects of soil-structure and granular material-structure interaction on the seismic response of a flat-bottom reinforced concrete silo
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作者 Sonia Benkhellat Mohammed Kadri Abdelghani Seghir 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第3期609-623,共15页
In this work,a numerical study of the effects of soil-structure interaction(SSI)and granular material-structure interaction(GSI)on the nonlinear response and seismic capacity of flat-bottomed storage silos is conducte... In this work,a numerical study of the effects of soil-structure interaction(SSI)and granular material-structure interaction(GSI)on the nonlinear response and seismic capacity of flat-bottomed storage silos is conducted.A series of incremental dynamic analyses(IDA)are performed on a case of large reinforced concrete silo using 10 seismic recordings.The IDA results are given by two average IDA capacity curves,which are represented,as well as the seismic capacity of the studied structure,with and without a consideration of the SSI while accounting for the effect of GSI.These curves are used to quantify and evaluate the damage of the studied silo by utilizing two damage indices,one based on dissipated energy and the other on displacement and dissipated energy.The cumulative energy dissipation curves obtained by the average IDA capacity curves with and without SSI are presented as a function of the base shear,and these curves allow one to obtain the two critical points and the different limit states of the structure.It is observed that the SSI and GSI significantly influence the seismic response and capacity of the studied structure,particularly at higher levels of PGA.Moreover,the effect of the SSI reduces the damage index of the studied structure by 4%. 展开更多
关键词 reinforced concrete silo perfectly matched layers soil-structure interaction granular material-structure interaction effective seismic input method damage index
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Modelling of the variation of granular base materials resilient modulus with material characteristics and humidity conditions
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作者 Jean-Pascal Bilodeau Erdrick Leandro Perez-Gonzalez Ali Saeidi 《Journal of Road Engineering》 2024年第1期27-35,共9页
This study aims to quantify the susceptibility of granular materials used in pavements to changes in moisture content and propose a correlation model to incorporate this susceptibility into seasonal analyses.The fines... This study aims to quantify the susceptibility of granular materials used in pavements to changes in moisture content and propose a correlation model to incorporate this susceptibility into seasonal analyses.The fines content and the percentage of fractured coarse aggregates were identified as direct indicators of the resilient modulus susceptibility to changes in water content.The results showed that the percentage of fractured coarse aggregates particles(FR)has a more significant impact on the resilient modulus(Er)of crushed granular materials used in pavement construction than the combined indicator of the fines content and sample volumetrics(nf).Crushed granular materials with a higher percentage of fractured coarse aggregates are relatively insensitive to changes in the degree of saturation,but become more sensitive as the fine fraction porosity decreases.An adjusted model was proposed based on the existing formulation,but considers a complex parameter to describe and adjust the sensitivity of base granular materials to variations in moisture content with respect to fabrication charac-teristics,fines content and volumetric properties.The model shows that the variation of Er values is below10%for fully crushed granular materials.However,it reaches approximately±12%for materials with 75%of crushed coarse aggregates andþ40%and-25%for materials with FR=50%.This model could help select good ag-gregates characteristics and adjust grain-size distribution for environments where significant moisture content variations can occur in the pavement system,such as in the Province of Quebec(Canada).As it is based on pa-rameters that can be easily determined or estimated,it also represents a valuable tool for detailed design and analysis that can consider material characteristics. 展开更多
关键词 Resilient modulus Degree of saturation Humidity conditions Unbound granular materials Pavement base
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Multi-Granularity Neighborhood Fuzzy Rough Set Model on Two Universes
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作者 Ju Wang Xinghu Ai Li Fu 《Journal of Intelligent Learning Systems and Applications》 2024年第2期91-106,共16页
The two universes multi-granularity fuzzy rough set model is an effective tool for handling uncertainty problems between two domains with the help of binary fuzzy relations. This article applies the idea of neighborho... The two universes multi-granularity fuzzy rough set model is an effective tool for handling uncertainty problems between two domains with the help of binary fuzzy relations. This article applies the idea of neighborhood rough sets to two universes multi-granularity fuzzy rough sets, and discusses the two-universes multi-granularity neighborhood fuzzy rough set model. Firstly, the upper and lower approximation operators are defined in the two universes multi-granularity neighborhood fuzzy rough set model. Secondly, the properties of the upper and lower approximation operators are discussed. Finally, the properties of the two universes multi-granularity neighborhood fuzzy rough set model are verified through case studies. 展开更多
关键词 Fuzzy Set Two Universes Multi-granularity Rough Set Multi-granularity Neighborhood Fuzzy Rough Set
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A hyaluronic acid granular hydrogel nerve guidance conduit promotes regeneration and functional recovery of injured sciatic nerves in rats 被引量:2
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作者 Jie Yang Chia-Chen Hsu +3 位作者 Ting-Ting Cao Hua Ye Jing Chen Yun-Qing Li 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第3期657-663,共7页
A hyaluronic acid granular hydrogel can promote neuronal and astrocyte colony formation and axonal extension in vitro,suggesting that the hydrogel can simulate an extracellular matrix structure to promote neural regen... A hyaluronic acid granular hydrogel can promote neuronal and astrocyte colony formation and axonal extension in vitro,suggesting that the hydrogel can simulate an extracellular matrix structure to promote neural regeneration.However,in vivo experiments have not been conducted.In this study,we transplanted a hyaluronic acid granular hydrogel nerve guidance conduit to repair a 10-mm long sciatic nerve gap.The Basso,Beattie,and Bresnahan locomotor rating scale,sciatic nerve compound muscle action potential recording,Fluoro-Gold retrograde tracing,growth related protein 43/S100 immunofluorescence staining,transmission electron microscopy,gastrocnemius muscle dry/wet weight ratio,and Masson’s trichrome staining results showed that the nerve guidance conduit exhibited similar regeneration of sciatic nerve axons and myelin sheath,and recovery of the electrophysiological function and motor function as autologous nerve transplantation.The conduit results were superior to those of a bulk hydrogel or silicone tube transplant.These findings suggest that tissue-engineered nerve conduits containing hyaluronic acid granular hydrogels effectively promote the morphological and functional recovery of the injured sciatic nerve.The nerve conduits have the potential as a material for repairing peripheral nerve defects. 展开更多
关键词 functional recovery granular hydrogel hyaluronic acid myelin sheath nerve conduit nerve regeneration peripheral nerve regeneration sciatic nerve injury tissue engineering transection injury
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Constitutive modelling of idealised granular materials using machine learning method 被引量:1
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作者 Mengmeng Wu Zhangqi Xia Jianfeng Wang 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2023年第4期1038-1051,共14页
Predicting the constitutive response of granular soils is a fundamental goal in geomechanics.This paper presents a machine learning(ML)framework for the prediction of the stress-strain behaviour and shearinduced conta... Predicting the constitutive response of granular soils is a fundamental goal in geomechanics.This paper presents a machine learning(ML)framework for the prediction of the stress-strain behaviour and shearinduced contact fabric evolution of an idealised granular material subject to triaxial shearing.The MLbased framework is comprised of a set of mini-triaxial tests which provide a benchmark for the setup and validation of the discrete element method(DEM)model of the granular materials,a parametric DEM simulation programme of virtual triaxial tests which provides datasets of micro-and macro-mechanical information,as well as a multi-layer perceptron(MLP)neural network which is trained and tested using the DEM-based datasets.The ML model only requires the initial void ratio of the granular sample as the input for predicting its constitutive response.The excellent agreement between the ML model prediction and experimental test and DEM simulation results indicates that the MLebased modelling approach is capable of capturing accurately the effects of initial void ratio on the constitutive behaviour of idealised granular materials,bypassing the need to incorporate the complex micromechanics underlying the macroscopic mechanical behaviour of granular materials.Lastly,a detailed comparison between the used MLP model and long short-term memory(LSTM)model was made from the perspective of technical algorithm,prediction accuracy,and computational efficiency. 展开更多
关键词 Machine learning(ML) Multi-layer perceptron(MLP) Contact fabric granular material Discrete element method(DEM)
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Central Granular Cell Odontogenic Tumor: A Literature Review of Cases Reported in the Last 71 Years with a New Case Report
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作者 Fatemeh Mashhadiabbas Sanaz GholamiToghchi Roohollah Safarpour 《Chinese Medical Sciences Journal》 CAS CSCD 2023年第2期138-146,共9页
Central granular cell odontogenic tumors(CGCOTs)are rare,benign,slowly growing odontogenic neoplasms.Due to their uncertain histogenesis,CGCOTs are still not included as a distinct entity in the WHO classification(201... Central granular cell odontogenic tumors(CGCOTs)are rare,benign,slowly growing odontogenic neoplasms.Due to their uncertain histogenesis,CGCOTs are still not included as a distinct entity in the WHO classification(2017)of odontogenic tumors.We report a case of CGCOT involving the right side of maxillary anterior region of a 39-year-old white female.Immunohistochemical staining showed that granular cells positively expressed CD68 and vimentin,and negatively expressed S-100 protein.Meanwhile,we searched Pub Med,Google Scholar,and Scopus databases to summary the clinico-pathological features of 51 reported cases of CGCOT.The results showed that the granular cells of 28.6%cases were immunopositive for vimentin and CD68,and odontogenic epithelial cells were positive immunoreactivity for cytokeratin.These findings reinforced the mesenchymal origin of granular cells and the odontogenic nature of epithelium islands. 展开更多
关键词 central granular cell odontogenic tumor central granular cell odontogenic fibroma odontogenic tumor granular cell ameloblastic fibroma HISTOGENESIS
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Intruder trajectory tracking in a three-dimensional vibration-driven granular system:Unveiling the mechanism of the Brazil nut effect
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作者 李拓 程可 +2 位作者 彭政 杨晖 厚美瑛 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第10期106-111,共6页
We employ a Hall-effect magnetic sensor array to accurately track the trajectory of a single magnetic sphere,referred to as the“intruder,”within a three-dimensional vibro-fluidized granular bed to unravel the underl... We employ a Hall-effect magnetic sensor array to accurately track the trajectory of a single magnetic sphere,referred to as the“intruder,”within a three-dimensional vibro-fluidized granular bed to unravel the underlying physical mechanism governing the motion of the intruder.Within the acceleration range of 3.5 g≥Γ≥1.5 g,we find that,regardless of the intruder's initial position,it consistently reaches the same equilibrium depth when the vibration acceleration(Γ)and frequency(ω)are fixed.ForΓ≤2.5 g,the equilibrium position lies on the surface of the granular bed,while forΓ>2.5 g,it shifts below the surface.Additionally,intruders with different densities exhibit varying equilibrium depths,with higher density resulting in a deeper equilibrium position.To understand the mechanism behind the intruder's upward or downward motion,we measure its rising or sinking velocities under different vibration parameters.Our findings demonstrate that the rising velocity of the intruder,under varying vibration accelerations(Γ)and frequencies(ω),can be collapsed using the ratioΓ/ω,while the sinking velocity remains unaffected by the vibration strength.This confirms that the upward motion of the larger sphere,associated with the Brazil nut effect,primarily arises from the void-filling mechanism of the bed particles.Furthermore,our experiments reveal that the presence of convection within the bed particles has minimal impact on the motion of the intruder. 展开更多
关键词 granular matter SEGREGATION Brazil nut effect vibro-fluidization
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Resistance law of a rod penetrating a multilayer granular raft
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作者 李宗霖 田强 胡海岩 《Chinese Physics B》 SCIE EI CAS CSCD 2023年第3期354-362,共9页
This paper presents an experimental study on the resistance law of a rod vertically penetrating different kinds of multilayer granular rafts with a constant velocity so as to reveal the mechanical properties of the mu... This paper presents an experimental study on the resistance law of a rod vertically penetrating different kinds of multilayer granular rafts with a constant velocity so as to reveal the mechanical properties of the multilayer granular rafts.The resistance was quasi-static under the chosen velocity.Experiments were conducted with different granular thicknesses,rod diameters and combinations of particles and liquids.The study shows that the resistance–displacement relation of the rod has three smooth stages.In the first stage,the resistance rapidly increased.In the second stage,the resistance curve maintained an almost constant slope.In the third stage,the resistance smoothly changed with its slope continuously increasing.Based on the corresponding physical models for each stage,the study reveals the exponential dependence of the load-bearing capacity of the multilayer granular raft on its thickness,and clarifies the capillary effects on the resistance law.The study extends the knowledge of the granular raft from monolayer to multilayer structure. 展开更多
关键词 granular matter wet particles saturated particles capillary effects
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