With the frequent information accesses from users to the Internet, it is important to organize and allocate information resources properly on different web servers. This paper considers the following problem; Due to t...With the frequent information accesses from users to the Internet, it is important to organize and allocate information resources properly on different web servers. This paper considers the following problem; Due to the capacity limitation of each single web server, it is impossible to put all information resources on one web server. Hence it is an important problem to put them on several different servers such as: (1) the amount of information resources assigned on any server is less than its capacity; (2) the access bottleneck can be avoided. In order to solve the problem in which the access frequency is variable, this paper proposes a dynamic optimal modeling. Based on the computational complexity results, the paper further focuses on the genetic algorithm for solving the dynamic problem. Finally we give the simulation results and conclusions.展开更多
Sarcopenia reflects patient frailty and should be routinely assessed due to its high prevalence in cirrhotic patients awaiting liver transplants.Pre-transplant nutritional optimization should be tailored for patients ...Sarcopenia reflects patient frailty and should be routinely assessed due to its high prevalence in cirrhotic patients awaiting liver transplants.Pre-transplant nutritional optimization should be tailored for patients with a definitive diagnosis of sarcopenia,therefore improving functional status at transplant and reducing posttransplant mortality.Hepatologists and transplant surgeons should have raised awareness regarding sarcopenia and the reflected frailty that hinder posttransplant outcomes.The policymakers should also take into account when modifying the organ allocation model that sarcopenia or frailty might become a decisive factor in allocating organs for cirrhotic patients,in order to ensure post-transplant survival and quality of life.展开更多
[Objective] To examine the effect of endophytic fungi ALl2 (Gilmaniella sp.) on metabolites distribution in organs of Atractylodes lancea. [Method] Endophytic fungi ALl2 was inoculated on Atraetylodes lancea plantle...[Objective] To examine the effect of endophytic fungi ALl2 (Gilmaniella sp.) on metabolites distribution in organs of Atractylodes lancea. [Method] Endophytic fungi ALl2 was inoculated on Atraetylodes lancea plantlets in tissue culture, and the distribution of cellulose, hemicellulose, lignin, soluble sugar in leaves and roots of the inoculated group were detected. The weight of leaves and roots were compared. Gas Chromatography was used to analyze the volatile oil components. [Result] Compared with the control group, the average fresh weight and dry weight of leaves and roots of A. lancea which had been symbiosed with ALl2 increased significantly. The content of lignin and soluble sugar increased in the leaves of the inoculated group, and the content of cellulose, hemicellulose, lignin, soluble sugar and volatile oil also increased in roots. [Conclusion] The results indicate that symbiosed with ALl2 is benefit for the development of A. lancea roots and can promote the transfer and accumulation of the medicinal components to the roots.展开更多
In order to reveal the impact of various fertilization strategies on carbon(C) and nitrogen(N) accumulation and allocation in corn(Zea mays L.), corn was grown in the fields where continuous fertilization manage...In order to reveal the impact of various fertilization strategies on carbon(C) and nitrogen(N) accumulation and allocation in corn(Zea mays L.), corn was grown in the fields where continuous fertilization management had been lasted about 18 years at two sites located in Central and Northeast China(Zhengzhou and Gongzhuling), and biomass C and N contents in different organs of corn at harvest were analyzed. The fertilization treatments included non-fertilizer(control), chemical fertilizers of either nitrogen(N), or nitrogen and phosphorus(NP), or phosphorus and potassium(PK), or nitrogen, phosphorus and potassium(NPK), NPK plus manure(NPKM), 150% of the NPKM(1.5NPKM), and NPK plus straw(NPKS). The results showed that accumulated C in aboveground ranged from 2 550–5 630 kg ha^–1 in the control treatment to 9 300–9 610 kg ha^–1 in the NPKM treatment, of which 57–67% and 43–50% were allocated in the non-grain organs, respectively. Accumulated N in aboveground ranged from 44.8–55.2 kg ha^-1 in the control treatment to 211–222 kg ha^–1 in the NPKM treatment, of which 35–48% and 33–44% were allocated in the non-grain parts, respectively. C allocated to stem and leaf for the PK treatment was 65 and 49% higher than that for the NPKM treatment at the both sites, respectively, while N allocated to the organs for the PK treatment was 18 and 6% higher than that for the NPKM treatment, respectively. This study demonstrated that responses of C and N allocation in corn to fertilization strategies were different, and C allocation was more sensitive to fertilization treatments than N allocation in the area.展开更多
Since 1963,when the first human liver transplantation(LT)was performed by Thomas Starzl,the world has witnessed 50 years of development in surgical techniques,immunosuppression,organ allocation,donor selection,and the...Since 1963,when the first human liver transplantation(LT)was performed by Thomas Starzl,the world has witnessed 50 years of development in surgical techniques,immunosuppression,organ allocation,donor selection,and the indications and contraindications for LT.This has led to the mainstream,wellestablished procedure that has saved innumerable lives worldwide.Today,there are hundreds of liver transplant centres in over 80 countries.This review aims to describe the main aspects of LT regarding the progressive changes that have occurred over the years.We herein review historical aspects since the first experimental studies and the first attempts at human transplantation.We also provide an overview of immunosuppressive agents and their potential side effects,the evolution of the indications and contraindications of LT,the evolution of survival according to different time periods,and the evolution of methods of organ allocation.展开更多
Liver transplant for hepatitis B virus(HBV) currently yields excellent outcomes: it allows to rescue patients with an HBV-related advanced liver disease, resulting in a demographical modification of the waiting list f...Liver transplant for hepatitis B virus(HBV) currently yields excellent outcomes: it allows to rescue patients with an HBV-related advanced liver disease, resulting in a demographical modification of the waiting list for liver transplant. In an age of patient-tailored treatments, in liver transplantation as well the aim is to offer the best suitable graft to the patient who can benefit from it, also expanding the criteria for organ acceptance and allocation. With the intent of developing strategies to increase the donor pool, we set-up a multicenter study involving 3 Liver Transplant Centers in Italy: patients undergoing liver transplantation between March 03, 2004, and May 21, 2010, were retrospectively evaluated. 1408 patients underwent liver transplantation during the study period, 28(2%) received the graft from hepatitis B surface antigen positive(HBs Ag)-positive deceased donors. The average follow-up after liver transplantation was 63.7 mo [range: 0.1-119.4; SD ± 35.8]. None Primary nonfunction, re-liver transplantation, early or late hepatic artery thrombosis occurred. The 1-, 3-and 5-year graft and patient survival resulted of 85.7%, 82.1%, 78.4%. Our results suggest that the use of HBs Agpositive donors liver grafts is feasible, since HBV can be controlled without affecting graft stability. However, the selection of grafts and the postoperative antiviral therapy should be managed appropriately.展开更多
A point of interest (POI) is a specific point location that someone may find useful. With the development of urban modernization, a large number of functional organized POI groups (FOPGs), such as shopping malls, ...A point of interest (POI) is a specific point location that someone may find useful. With the development of urban modernization, a large number of functional organized POI groups (FOPGs), such as shopping malls, electronic malls, and snacks streets, are springing up in the city. They have a great influence on people's lives. We aim to discover functional organized POI groups for spatial keyword recommendation because FOPGs-based recommendation is superior to POIs-based recommendation in efficiency and flexibility. To discover FOPGs, we design clustering algorithms to obtain organized POI groups (OPGs) and utilize OPGs-LDA (Latent Dirichlet Allocation) model to reveal functions of OPGs for further recommendation. To the best of our knowledge, we are the first to study functional organized POI groups which have important applications in urban planning and social marketing.展开更多
基金Supportd by the Hi-tech Research and Development Program of China(2002AA1Z1490)
文摘With the frequent information accesses from users to the Internet, it is important to organize and allocate information resources properly on different web servers. This paper considers the following problem; Due to the capacity limitation of each single web server, it is impossible to put all information resources on one web server. Hence it is an important problem to put them on several different servers such as: (1) the amount of information resources assigned on any server is less than its capacity; (2) the access bottleneck can be avoided. In order to solve the problem in which the access frequency is variable, this paper proposes a dynamic optimal modeling. Based on the computational complexity results, the paper further focuses on the genetic algorithm for solving the dynamic problem. Finally we give the simulation results and conclusions.
文摘Sarcopenia reflects patient frailty and should be routinely assessed due to its high prevalence in cirrhotic patients awaiting liver transplants.Pre-transplant nutritional optimization should be tailored for patients with a definitive diagnosis of sarcopenia,therefore improving functional status at transplant and reducing posttransplant mortality.Hepatologists and transplant surgeons should have raised awareness regarding sarcopenia and the reflected frailty that hinder posttransplant outcomes.The policymakers should also take into account when modifying the organ allocation model that sarcopenia or frailty might become a decisive factor in allocating organs for cirrhotic patients,in order to ensure post-transplant survival and quality of life.
基金Supported by the National Natural Science Foundation of China(31070443,30970523)the National Science Foundation for Talents Training in Basic Science,China(J1103507)the Project of the Priority Academic Program Development of Jiangsu Higher Education Institutions,China~~
文摘[Objective] To examine the effect of endophytic fungi ALl2 (Gilmaniella sp.) on metabolites distribution in organs of Atractylodes lancea. [Method] Endophytic fungi ALl2 was inoculated on Atraetylodes lancea plantlets in tissue culture, and the distribution of cellulose, hemicellulose, lignin, soluble sugar in leaves and roots of the inoculated group were detected. The weight of leaves and roots were compared. Gas Chromatography was used to analyze the volatile oil components. [Result] Compared with the control group, the average fresh weight and dry weight of leaves and roots of A. lancea which had been symbiosed with ALl2 increased significantly. The content of lignin and soluble sugar increased in the leaves of the inoculated group, and the content of cellulose, hemicellulose, lignin, soluble sugar and volatile oil also increased in roots. [Conclusion] The results indicate that symbiosed with ALl2 is benefit for the development of A. lancea roots and can promote the transfer and accumulation of the medicinal components to the roots.
基金Financial supports from the National Basic Research Program of China(2011CB100501)the National Natural Science Foundation of China(41171239,41371247)are gratefully acknowledged
文摘In order to reveal the impact of various fertilization strategies on carbon(C) and nitrogen(N) accumulation and allocation in corn(Zea mays L.), corn was grown in the fields where continuous fertilization management had been lasted about 18 years at two sites located in Central and Northeast China(Zhengzhou and Gongzhuling), and biomass C and N contents in different organs of corn at harvest were analyzed. The fertilization treatments included non-fertilizer(control), chemical fertilizers of either nitrogen(N), or nitrogen and phosphorus(NP), or phosphorus and potassium(PK), or nitrogen, phosphorus and potassium(NPK), NPK plus manure(NPKM), 150% of the NPKM(1.5NPKM), and NPK plus straw(NPKS). The results showed that accumulated C in aboveground ranged from 2 550–5 630 kg ha^–1 in the control treatment to 9 300–9 610 kg ha^–1 in the NPKM treatment, of which 57–67% and 43–50% were allocated in the non-grain organs, respectively. Accumulated N in aboveground ranged from 44.8–55.2 kg ha^-1 in the control treatment to 211–222 kg ha^–1 in the NPKM treatment, of which 35–48% and 33–44% were allocated in the non-grain parts, respectively. C allocated to stem and leaf for the PK treatment was 65 and 49% higher than that for the NPKM treatment at the both sites, respectively, while N allocated to the organs for the PK treatment was 18 and 6% higher than that for the NPKM treatment, respectively. This study demonstrated that responses of C and N allocation in corn to fertilization strategies were different, and C allocation was more sensitive to fertilization treatments than N allocation in the area.
文摘Since 1963,when the first human liver transplantation(LT)was performed by Thomas Starzl,the world has witnessed 50 years of development in surgical techniques,immunosuppression,organ allocation,donor selection,and the indications and contraindications for LT.This has led to the mainstream,wellestablished procedure that has saved innumerable lives worldwide.Today,there are hundreds of liver transplant centres in over 80 countries.This review aims to describe the main aspects of LT regarding the progressive changes that have occurred over the years.We herein review historical aspects since the first experimental studies and the first attempts at human transplantation.We also provide an overview of immunosuppressive agents and their potential side effects,the evolution of the indications and contraindications of LT,the evolution of survival according to different time periods,and the evolution of methods of organ allocation.
文摘Liver transplant for hepatitis B virus(HBV) currently yields excellent outcomes: it allows to rescue patients with an HBV-related advanced liver disease, resulting in a demographical modification of the waiting list for liver transplant. In an age of patient-tailored treatments, in liver transplantation as well the aim is to offer the best suitable graft to the patient who can benefit from it, also expanding the criteria for organ acceptance and allocation. With the intent of developing strategies to increase the donor pool, we set-up a multicenter study involving 3 Liver Transplant Centers in Italy: patients undergoing liver transplantation between March 03, 2004, and May 21, 2010, were retrospectively evaluated. 1408 patients underwent liver transplantation during the study period, 28(2%) received the graft from hepatitis B surface antigen positive(HBs Ag)-positive deceased donors. The average follow-up after liver transplantation was 63.7 mo [range: 0.1-119.4; SD ± 35.8]. None Primary nonfunction, re-liver transplantation, early or late hepatic artery thrombosis occurred. The 1-, 3-and 5-year graft and patient survival resulted of 85.7%, 82.1%, 78.4%. Our results suggest that the use of HBs Agpositive donors liver grafts is feasible, since HBV can be controlled without affecting graft stability. However, the selection of grafts and the postoperative antiviral therapy should be managed appropriately.
基金This work was supported by the National Natural Science Foundation of China under Grant Nos. 61572335, 61472263, 61402312 and 61402313, the Natural Science Foundation of Jiangsu Province of China under Grant No. BK20151223, and the Collaborative Innovation Center of Novel Software Technology and Industrialization, Jiangsu, China.
文摘A point of interest (POI) is a specific point location that someone may find useful. With the development of urban modernization, a large number of functional organized POI groups (FOPGs), such as shopping malls, electronic malls, and snacks streets, are springing up in the city. They have a great influence on people's lives. We aim to discover functional organized POI groups for spatial keyword recommendation because FOPGs-based recommendation is superior to POIs-based recommendation in efficiency and flexibility. To discover FOPGs, we design clustering algorithms to obtain organized POI groups (OPGs) and utilize OPGs-LDA (Latent Dirichlet Allocation) model to reveal functions of OPGs for further recommendation. To the best of our knowledge, we are the first to study functional organized POI groups which have important applications in urban planning and social marketing.