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Enzymatic remodeling of heparan sulfate:a therapeutic strategy for systemic and localized amyloidoses?
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作者 Kazuchika Nishitsuji Hiroyuki Saito Kenji Uchimura 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第3期408-409,共2页
In 1854,Rudolf Virchow introduced the term"amyloid"to indicate white waxy deposits that stained positive for iodine and that were found in many organs of patients with chronic inflammatory diseases.He observed that ... In 1854,Rudolf Virchow introduced the term"amyloid"to indicate white waxy deposits that stained positive for iodine and that were found in many organs of patients with chronic inflammatory diseases.He observed that these deposits stained pale blue after treatment with iodine and became dark blue or black after subsequent addition of sulfuric acid,in a similar manner to that of cellulose or carbohydrate. 展开更多
关键词 heparan amyloid remodeling carbohydrate stained subsequent Virchow organs iodine cellulose
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