This study was designed to investigate the anti-inflammatory effects of volatile oil of Platycladus orientalis(L.)Franco leaves(VOPF)and the underlying molecular mechanisms by using the non-infectious inflammation rat...This study was designed to investigate the anti-inflammatory effects of volatile oil of Platycladus orientalis(L.)Franco leaves(VOPF)and the underlying molecular mechanisms by using the non-infectious inflammation rat models and infectious inflammation mouse models.Ear swelling and intraperitoneal capillary permeability in mice,and carrageenan-induced toe swelling and cotton ball-induced granuloma in rats were used to reveal anti-inflammatory effects of VOPF.Moreover,the lipopolysaccharide(LPS)-induced mouse model of acute lung injury was used to explore the anti-inflammatory mechanism of VOPF.The results showed that VOPF could significantly inhibit auricular swelling,intraperitoneal capillary permeability in mice,and reduce granuloma swelling and paw swelling in rats.Furthermore,it significantly alleviated the pathological damage of the lung tissue.In addition,VOPF could reduce the contents of IL-1β and TNF-αand increase the content of IL-10 in the serum.It had little effect on the expression of p65 but reduced the phosphorylation level of p65 and IκB in NF-κB pathway.In conclusion,VOPF has anti-inflammatory effects and the mechanisms involve the down-regulation of the phosphorylation levels of p65 and IκB and blockage of the NF-κB signaling pathway.展开更多
Effects of different Indole-3-Buteric Acid (IBA) concentrations (0, 1 000, 1 500 and 2 500 ppm) and curing types (soft wood, semi hard and hard wood) of plane tree were investigated with Randomized Complete Bloc...Effects of different Indole-3-Buteric Acid (IBA) concentrations (0, 1 000, 1 500 and 2 500 ppm) and curing types (soft wood, semi hard and hard wood) of plane tree were investigated with Randomized Complete Block Design (RCBD) at the Agricultural research station, Charsadda. The maximum survival percentage, plant height (cm), root length (era), numbers of roots and root weight per cutting were significantly higher in hard wood cuttings. IBA concentration had no speculative effect on plane tree cuttings. Thus, hard wood cutting was the best choice for plan tree propagation.展开更多
A pot experiment has been conducted in Faculty of Agricultural and Forestry, Lath House of Horticultural Department, School of Plant Production, Duhok University during the growing season 2010-2011. The study consiste...A pot experiment has been conducted in Faculty of Agricultural and Forestry, Lath House of Horticultural Department, School of Plant Production, Duhok University during the growing season 2010-2011. The study consisted of testing the effects of four different growth media (Clay, Loam, Clay + sheep manure (1:1) and Loam + sheep manure (1:1) as volumetric rates on vegetative and flowering growth characters of five different cultivars of Hyacinths plant (Blue Giant, City of Haarlem, Jon Bos, Delf Blue and Fondante). The experiment was laid out in randomized complete block design (RCBD) of two factors in three replicates. Media mostly affected the parameters studied during the experiment. Early emergence (22.53 days) and flowering (73.13 days) was recorded in medium consisting of loam and sheep manure, while maximum plant height (19.75 cm), leaves number (6.13), leaf area (31.47 cm2) were recorded in clay medium. Maximum number of florets plant-l (31.93) and spike length (7.95 cm) were recorded in medium consist of clay and sheep manure. Maximum length of spike stem (9.61 cm) and total chlorophyll percentage (53.45%) were recorded for loam medium. Among the cultivars, some parameters showed significant variation. Early emergence (20.42 days), maximum plant height (20.35 cm), leaf area per plant (33.01 cm2) and length of spike stem (15.10 cm) were given by cv. Fondante. Maximum number of florets plantl (35.58) and spike lengths (8.63 cm) were recorded by cv. Blue Giant. High percentage of total chlorophyll (58.15%) was recorded in cv. Jon Bos..展开更多
Sigesbeckiae Herba,a dry whole plant of Sigesbeckia glabrescens Makino,Sigesbeckia pubescens Makino and Sigesbeckia orientalis L.,is a traditional Chinese medicine used to dispel dampness,dredge meridians and collater...Sigesbeckiae Herba,a dry whole plant of Sigesbeckia glabrescens Makino,Sigesbeckia pubescens Makino and Sigesbeckia orientalis L.,is a traditional Chinese medicine used to dispel dampness,dredge meridians and collaterals,clear heat and detoxicate.Its chemical components are complex and abundant,including mainly diterpenoids,sesquiterpenoids and flavonoids.Among them,diterpenoids are the main active components.Modern pharmacological studies have found that the compounds isolated from Sigesbeckiae Herba have anti-inflammatory,anti-tumor,antithrombus and other pharmacological activities.This review systematically summarized the chemical components identified from Sigesbeckiae Herba and their pharmacological activities by searching Chinese and English databases,in order to provide references for the further development of Sigesbeckiae Herba and the improvement of its quality standards.展开更多
基金the National Natural Science Foundation of China(No.31200264)the Fundamental Research Funds for Central Universities(South-Central University for NationalitiesNo.CZY19028,No.CZY20048).
文摘This study was designed to investigate the anti-inflammatory effects of volatile oil of Platycladus orientalis(L.)Franco leaves(VOPF)and the underlying molecular mechanisms by using the non-infectious inflammation rat models and infectious inflammation mouse models.Ear swelling and intraperitoneal capillary permeability in mice,and carrageenan-induced toe swelling and cotton ball-induced granuloma in rats were used to reveal anti-inflammatory effects of VOPF.Moreover,the lipopolysaccharide(LPS)-induced mouse model of acute lung injury was used to explore the anti-inflammatory mechanism of VOPF.The results showed that VOPF could significantly inhibit auricular swelling,intraperitoneal capillary permeability in mice,and reduce granuloma swelling and paw swelling in rats.Furthermore,it significantly alleviated the pathological damage of the lung tissue.In addition,VOPF could reduce the contents of IL-1β and TNF-αand increase the content of IL-10 in the serum.It had little effect on the expression of p65 but reduced the phosphorylation level of p65 and IκB in NF-κB pathway.In conclusion,VOPF has anti-inflammatory effects and the mechanisms involve the down-regulation of the phosphorylation levels of p65 and IκB and blockage of the NF-κB signaling pathway.
文摘Effects of different Indole-3-Buteric Acid (IBA) concentrations (0, 1 000, 1 500 and 2 500 ppm) and curing types (soft wood, semi hard and hard wood) of plane tree were investigated with Randomized Complete Block Design (RCBD) at the Agricultural research station, Charsadda. The maximum survival percentage, plant height (cm), root length (era), numbers of roots and root weight per cutting were significantly higher in hard wood cuttings. IBA concentration had no speculative effect on plane tree cuttings. Thus, hard wood cutting was the best choice for plan tree propagation.
文摘A pot experiment has been conducted in Faculty of Agricultural and Forestry, Lath House of Horticultural Department, School of Plant Production, Duhok University during the growing season 2010-2011. The study consisted of testing the effects of four different growth media (Clay, Loam, Clay + sheep manure (1:1) and Loam + sheep manure (1:1) as volumetric rates on vegetative and flowering growth characters of five different cultivars of Hyacinths plant (Blue Giant, City of Haarlem, Jon Bos, Delf Blue and Fondante). The experiment was laid out in randomized complete block design (RCBD) of two factors in three replicates. Media mostly affected the parameters studied during the experiment. Early emergence (22.53 days) and flowering (73.13 days) was recorded in medium consisting of loam and sheep manure, while maximum plant height (19.75 cm), leaves number (6.13), leaf area (31.47 cm2) were recorded in clay medium. Maximum number of florets plant-l (31.93) and spike length (7.95 cm) were recorded in medium consist of clay and sheep manure. Maximum length of spike stem (9.61 cm) and total chlorophyll percentage (53.45%) were recorded for loam medium. Among the cultivars, some parameters showed significant variation. Early emergence (20.42 days), maximum plant height (20.35 cm), leaf area per plant (33.01 cm2) and length of spike stem (15.10 cm) were given by cv. Fondante. Maximum number of florets plantl (35.58) and spike lengths (8.63 cm) were recorded by cv. Blue Giant. High percentage of total chlorophyll (58.15%) was recorded in cv. Jon Bos..
基金This work was supported by the National Natural Science Foundation of China(No.81903789)the China Postdoctoral Science Foundation(No.2020M670675&No.2020M680988)College Student Innovation and Entrepreneurship Training Program(No.S202010163009).
文摘Sigesbeckiae Herba,a dry whole plant of Sigesbeckia glabrescens Makino,Sigesbeckia pubescens Makino and Sigesbeckia orientalis L.,is a traditional Chinese medicine used to dispel dampness,dredge meridians and collaterals,clear heat and detoxicate.Its chemical components are complex and abundant,including mainly diterpenoids,sesquiterpenoids and flavonoids.Among them,diterpenoids are the main active components.Modern pharmacological studies have found that the compounds isolated from Sigesbeckiae Herba have anti-inflammatory,anti-tumor,antithrombus and other pharmacological activities.This review systematically summarized the chemical components identified from Sigesbeckiae Herba and their pharmacological activities by searching Chinese and English databases,in order to provide references for the further development of Sigesbeckiae Herba and the improvement of its quality standards.