Umbilical metastasis from gynecologic malignancies is very rare. We report 15 patients with primary gynecologic malignant tumours associated with umbilical metastases treated in this hospital from 1958 to Jan.1991, in...Umbilical metastasis from gynecologic malignancies is very rare. We report 15 patients with primary gynecologic malignant tumours associated with umbilical metastases treated in this hospital from 1958 to Jan.1991, including 10 epithelial ovarian cancer, 1 malignant teratoma of the ovary, 2 endometrial carcinoma and 2 squamous cell carcinoma of the cervix. Excepting l patient initially diagnosed as stage I endometrial carcinoma, all patients had advanced tumours. Umbilical lesions were discovered at the time of initial diagnosis of the primary tumour in 6 cases.The main clinical finding is an umbilical nodule or an ulcerated nodule in a diameter less than 2 cm.Usually the prognosis was poor. The average survival from initial diagnosis of umbilical metastasis to death was 14 months in 12 patients. There were 4 cases with longer survival, including 1 patient with endometrial carcinoma who survived for 40 months, and 3 Patients with ovarian carcinoma who survived for 54, 52, 31 months, respectively. Two cases are surviving with tumour. It indicates that aggressive therapy may prolong survival time, especially in patient with ovarian cancer.展开更多
文摘Umbilical metastasis from gynecologic malignancies is very rare. We report 15 patients with primary gynecologic malignant tumours associated with umbilical metastases treated in this hospital from 1958 to Jan.1991, including 10 epithelial ovarian cancer, 1 malignant teratoma of the ovary, 2 endometrial carcinoma and 2 squamous cell carcinoma of the cervix. Excepting l patient initially diagnosed as stage I endometrial carcinoma, all patients had advanced tumours. Umbilical lesions were discovered at the time of initial diagnosis of the primary tumour in 6 cases.The main clinical finding is an umbilical nodule or an ulcerated nodule in a diameter less than 2 cm.Usually the prognosis was poor. The average survival from initial diagnosis of umbilical metastasis to death was 14 months in 12 patients. There were 4 cases with longer survival, including 1 patient with endometrial carcinoma who survived for 40 months, and 3 Patients with ovarian carcinoma who survived for 54, 52, 31 months, respectively. Two cases are surviving with tumour. It indicates that aggressive therapy may prolong survival time, especially in patient with ovarian cancer.
