Culture-independent molecular techniques have demonstrated that the majority of the gut microbiota is uncultivable.Application of these molecular techniques to more accurately identify the indigenous gut microbiome ha...Culture-independent molecular techniques have demonstrated that the majority of the gut microbiota is uncultivable.Application of these molecular techniques to more accurately identify the indigenous gut microbiome has moved with great pace over recent years,leading to a substantial increase in understanding of gut microbial communities in both health and a number of disorders,including irritable bowel syndrome(IBS).Use of culture-independent molecular techniques already employed to characterise faecal and,to a lesser extent,colonic mucosal microbial populations in IBS,without reliance on insensitive,traditional microbiological culture techniques,has the potential to more accurately determine microbial composition in the small intestine of patients with this disorder,at least that occurring proximally and within reach of sampling.Current data concerning culture-based and culture-independent analyses of the small intestinal microbiome in IBS are considered here.展开更多
目的探讨未经手术治疗的食管和/或贲门癌性狭窄支架置入术后1年内再狭窄部位组织的病理形态学特征。方法收集黄石市三家医院6年来食管和/或贲门癌性狭窄支架置入术治疗患者85例,术后1年内再狭窄部位取活检组织进行病理分析。结果 85例...目的探讨未经手术治疗的食管和/或贲门癌性狭窄支架置入术后1年内再狭窄部位组织的病理形态学特征。方法收集黄石市三家医院6年来食管和/或贲门癌性狭窄支架置入术治疗患者85例,术后1年内再狭窄部位取活检组织进行病理分析。结果 85例未经手术治疗,采取支架置入术,患者术后1年内再狭窄者44例,25例因肿瘤组织过生长(tumor-overgrowing,TG)引起,19例系肉芽组织形成及纤维化(granulation and fibrosis,GF)引起;支架上端再狭窄19例中,TG7例、GF12例:支架下端再狭窄21例中,TG15例、GF6例,上下端均有再狭窄4例。结论食管和/或贲门癌性狭窄支架置入术后1年内再狭窄的发生,部分由TG引起,部分是由GF引起。支架上端再狭窄以GF多见,下端再狭窄以TG多见。展开更多
文摘Culture-independent molecular techniques have demonstrated that the majority of the gut microbiota is uncultivable.Application of these molecular techniques to more accurately identify the indigenous gut microbiome has moved with great pace over recent years,leading to a substantial increase in understanding of gut microbial communities in both health and a number of disorders,including irritable bowel syndrome(IBS).Use of culture-independent molecular techniques already employed to characterise faecal and,to a lesser extent,colonic mucosal microbial populations in IBS,without reliance on insensitive,traditional microbiological culture techniques,has the potential to more accurately determine microbial composition in the small intestine of patients with this disorder,at least that occurring proximally and within reach of sampling.Current data concerning culture-based and culture-independent analyses of the small intestinal microbiome in IBS are considered here.
文摘目的探讨未经手术治疗的食管和/或贲门癌性狭窄支架置入术后1年内再狭窄部位组织的病理形态学特征。方法收集黄石市三家医院6年来食管和/或贲门癌性狭窄支架置入术治疗患者85例,术后1年内再狭窄部位取活检组织进行病理分析。结果 85例未经手术治疗,采取支架置入术,患者术后1年内再狭窄者44例,25例因肿瘤组织过生长(tumor-overgrowing,TG)引起,19例系肉芽组织形成及纤维化(granulation and fibrosis,GF)引起;支架上端再狭窄19例中,TG7例、GF12例:支架下端再狭窄21例中,TG15例、GF6例,上下端均有再狭窄4例。结论食管和/或贲门癌性狭窄支架置入术后1年内再狭窄的发生,部分由TG引起,部分是由GF引起。支架上端再狭窄以GF多见,下端再狭窄以TG多见。