Objective:To study the clinical effect of modified circumcision in the treatment of phimosis and excessive foreskin.Methods:110 patients with overly long foreskin or phimosis were divided into experimental group and c...Objective:To study the clinical effect of modified circumcision in the treatment of phimosis and excessive foreskin.Methods:110 patients with overly long foreskin or phimosis were divided into experimental group and control group by random number table method,with 55 cases in each group.The experimental group was treated with modified circumcision,and the control group was treated with traditional manual cutting and suture.Then the clinical effects of the two treatments were compared.Results:Two different surgical procedures were performed.During the operation,the blood loss of the experimental group was less than that of the control group;the operation time and wound healing time were shorter than those of the control group;after the operation,the incidence of related complications in the experimental group was 14.55%,which was significantly lower than For 25.45%of the control group,the clinical treatment effect was obvious,and the difference was statistically significant(P<0.05).Conclusion:The clinical effect of modified circumcision in the treatment of patients with phimosis and excessive foreskin is good.Compared with the traditional manual cutting and suture treatment,it not only has the advantages of simple operation and clinical application,but also benefits the rehabilitation of patients.Rehabilitation time reduces the incidence of postoperative complications.It is an ideal treatment plan for this type of disease in the current clinic,and it is worthy of popularization and application in general surgery and reproductive surgery.展开更多
The plasma membrane Na＋/H＋-antiporter salt overly sensitive1 （SOS1） from the halophytic Arabidopsis-relative Thellungiella halophila （ThSOS1） shows conserved sequence and domain structure with the orthologous ge...The plasma membrane Na＋/H＋-antiporter salt overly sensitive1 （SOS1） from the halophytic Arabidopsis-relative Thellungiella halophila （ThSOS1） shows conserved sequence and domain structure with the orthologous genes from Arabidopsis thaliana and other plants. When expression of ThSOSt was reduced by RNA interference （RNAi）, pronounced characteristics of salt-sensitivity were observed. We were interested in monitoring altered transcriptional responses between Thellungiella wild type and thsost-4, a representative RNAi line with particular emphasis on root responses to salt stress at 350 mmol/L NaCI, a concentration that is only moderately stressful for mature wild type plants. Transcript profiling revealed several functional categories of genes that were differently affected in wild-type and RNAi plants. Down-regulation of SOS1 resulted in different gene expression even in the absence of stress. The pattern of gene induction in the RNAi plant under salt stress was similar to that of glycophytic Arabidopsis rather than that of wild type Thellungiella. The RNAi plants failed to down-regulate functions that are normally reduced in wild type Thellungiella upon stress and did not up-regulate functions that characterize the Thellungiella salt stress response. Metabolite changes observed in wild type Thellungiella after salt stress were less pronounced or absent in RNAi plants. Transcript and metabolite behavior suggested SOS1 functions including but also extending its established function as a sodium transporter. The down-regulation of ThSOS1 converted the halophyte Thellungiella into a salt-sensitive plant.展开更多
文摘Objective:To study the clinical effect of modified circumcision in the treatment of phimosis and excessive foreskin.Methods:110 patients with overly long foreskin or phimosis were divided into experimental group and control group by random number table method,with 55 cases in each group.The experimental group was treated with modified circumcision,and the control group was treated with traditional manual cutting and suture.Then the clinical effects of the two treatments were compared.Results:Two different surgical procedures were performed.During the operation,the blood loss of the experimental group was less than that of the control group;the operation time and wound healing time were shorter than those of the control group;after the operation,the incidence of related complications in the experimental group was 14.55%,which was significantly lower than For 25.45%of the control group,the clinical treatment effect was obvious,and the difference was statistically significant(P<0.05).Conclusion:The clinical effect of modified circumcision in the treatment of patients with phimosis and excessive foreskin is good.Compared with the traditional manual cutting and suture treatment,it not only has the advantages of simple operation and clinical application,but also benefits the rehabilitation of patients.Rehabilitation time reduces the incidence of postoperative complications.It is an ideal treatment plan for this type of disease in the current clinic,and it is worthy of popularization and application in general surgery and reproductive surgery.
文摘The plasma membrane Na＋/H＋-antiporter salt overly sensitive1 （SOS1） from the halophytic Arabidopsis-relative Thellungiella halophila （ThSOS1） shows conserved sequence and domain structure with the orthologous genes from Arabidopsis thaliana and other plants. When expression of ThSOSt was reduced by RNA interference （RNAi）, pronounced characteristics of salt-sensitivity were observed. We were interested in monitoring altered transcriptional responses between Thellungiella wild type and thsost-4, a representative RNAi line with particular emphasis on root responses to salt stress at 350 mmol/L NaCI, a concentration that is only moderately stressful for mature wild type plants. Transcript profiling revealed several functional categories of genes that were differently affected in wild-type and RNAi plants. Down-regulation of SOS1 resulted in different gene expression even in the absence of stress. The pattern of gene induction in the RNAi plant under salt stress was similar to that of glycophytic Arabidopsis rather than that of wild type Thellungiella. The RNAi plants failed to down-regulate functions that are normally reduced in wild type Thellungiella upon stress and did not up-regulate functions that characterize the Thellungiella salt stress response. Metabolite changes observed in wild type Thellungiella after salt stress were less pronounced or absent in RNAi plants. Transcript and metabolite behavior suggested SOS1 functions including but also extending its established function as a sodium transporter. The down-regulation of ThSOS1 converted the halophyte Thellungiella into a salt-sensitive plant.
