Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique

BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer patients.METHODS In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October 2022.The incidence of postoperative delirium was recorded for 7 d post-surgery.Patients were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative delirium.The SMOTE technique was applied to enhance the model by oversampling the delirium cases.The model’s predictive accuracy was then validated.RESULTS In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative delirium.These included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain score.The incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of 0.862.In comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive approaches.CONCLUSION This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of traditional methods,effectively addressing data imbalance.

Real-time prediction of rock mass classification based on TBM operation big data and stacking technique of ensemble learning

Real-time prediction of the rock mass class in front of the tunnel face is essential for the adaptive adjustment of tunnel boring machines(TBMs).During the TBM tunnelling process,a large number of operation data are generated,reflecting the interaction between the TBM system and surrounding rock,and these data can be used to evaluate the rock mass quality.This study proposed a stacking ensemble classifier for the real-time prediction of the rock mass classification using TBM operation data.Based on the Songhua River water conveyance project,a total of 7538 TBM tunnelling cycles and the corresponding rock mass classes are obtained after data preprocessing.Then,through the tree-based feature selection method,10 key TBM operation parameters are selected,and the mean values of the 10 selected features in the stable phase after removing outliers are calculated as the inputs of classifiers.The preprocessed data are randomly divided into the training set(90%)and test set(10%)using simple random sampling.Besides stacking ensemble classifier,seven individual classifiers are established as the comparison.These classifiers include support vector machine(SVM),k-nearest neighbors(KNN),random forest(RF),gradient boosting decision tree(GBDT),decision tree(DT),logistic regression(LR)and multilayer perceptron(MLP),where the hyper-parameters of each classifier are optimised using the grid search method.The prediction results show that the stacking ensemble classifier has a better performance than individual classifiers,and it shows a more powerful learning and generalisation ability for small and imbalanced samples.Additionally,a relative balance training set is obtained by the synthetic minority oversampling technique(SMOTE),and the influence of sample imbalance on the prediction performance is discussed.

Soft ground tunnel lithology classification using clustering-guided light gradient boosting machine

During tunnel boring machine(TBM)excavation,lithology identification is an important issue to understand tunnelling performance and avoid time-consuming excavation.However,site investigation generally lacks ground samples and the information is subjective,heterogeneous,and imbalanced due to mixed ground conditions.In this study,an unsupervised(K-means)and synthetic minority oversampling technique(SMOTE)-guided light-gradient boosting machine(LightGBM)classifier is proposed to identify the soft ground tunnel classification and determine the imbalanced issue of tunnelling data.During the tunnel excavation,an earth pressure balance(EPB)TBM recorded 18 different operational parameters along with the three main tunnel lithologies.The proposed model is applied using Python low-code PyCaret library.Next,four decision tree-based classifiers were obtained in a short time period with automatic hyperparameter tuning to determine the best model for clustering-guided SMOTE application.In addition,the Shapley additive explanation(SHAP)was implemented to avoid the model black box problem.The proposed model was evaluated using different metrics such as accuracy,F1 score,precision,recall,and receiver operating characteristics(ROC)curve to obtain a reasonable outcome for the minority class.It shows that the proposed model can provide significant tunnel lithology identification based on the operational parameters of EPB-TBM.The proposed method can be applied to heterogeneous tunnel formations with several TBM operational parameters to describe the tunnel lithologies for efficient tunnelling.

An ensemble learning classifier to discover arsenene catalysts with implanted heteroatoms for hydrogen evolution reaction

Accurate regulation of two-dimensional materials has become an effective strategy to develop a wide range of catalytic applications.The introduction of heterogeneous components has a significant impact on the performance of materials,which makes it difficult to discover and understand the structure-property relationships at the atomic level.Here,we developed a novel and efficient ensemble learning classifier with synthetic minority oversampling technique(SMOTE) to discover all possible arsenene catalysts with implanted heteroatoms for hydrogen evolution reaction(HER).A total of 850 doped arsenenes were collected as a database and 140 modified arsenene materials with different doping atoms and doping sites were identified as promising candidate catalysts for HER,with a machine learning prediction accuracy of 81%.Based on the results of machine learning,we proposed 13 low-cost and easily synthesized two-dimensional Fe-doped arsenene catalytic materials that are expected to contribute to high-efficient HER.The proposed ensemble method achieved high prediction accuracy,but millions of times faster to predict Gibbs free energies and only required a small amount of data.This study indicates that the presented ensemble learning classifier is capable of screening high-efficient catalysts,and can be further extended to predict other two-dimensional catalysts with delicate regulation.

Dealing with the Class Imbalance Problem in the Detection of Fake Job Descriptions

In recent years,the detection of fake job descriptions has become increasingly necessary because social networking has changed the way people access burgeoning information in the internet age.Identifying fraud in job descriptions can help jobseekers to avoid many of the risks of job hunting.However,the problem of detecting fake job descriptions comes up against the problem of class imbalance when the number of genuine jobs exceeds the number of fake jobs.This causes a reduction in the predictability and performance of traditional machine learning models.We therefore present an efficient framework that uses an oversampling technique called FJD-OT(Fake Job Description Detection Using Oversampling Techniques)to improve the predictability of detecting fake job descriptions.In the proposed framework,we apply several techniques including the removal of stop words and the use of a tokenizer to preprocess the text data in the first module.We then use a bag of words in combination with the term frequency-inverse document frequency(TF-IDF)approach to extract the features from the text data to create the feature dataset in the second module.Next,our framework applies k-fold cross-validation,a commonly used technique to test the effectiveness of machine learning models,that splits the experimental dataset[the Employment Scam Aegean(ESA)dataset in our study]into training and test sets for evaluation.The training set is passed through the third module,an oversampling module in which the SVMSMOTE method is used to balance data before training the classifiers in the last module.The experimental results indicate that the proposed approach significantly improves the predictability of fake job description detection on the ESA dataset based on several popular performance metrics.

Solution of the effects of twinning in femtosecond X-ray protein nanocrystallography

With the development of the XFEL （X-ray free electron laser）, high quality diffraction patterns from nanocrystals have been achieved. The nanocrystals with different sizes and random orientations are injected to the XFEL beams and the diffraction patterns can be obtained by the so-called ＂diffraction-and-destruction＂ mode. The recovery of orientations is one of the most critical steps in reconstructing the 3D structure of nanocrystals. There is already an approach to solve the orientation problem by using the automated indexing software in crystallography. However, this method cannot distinguish the twin orientations in the cases of the symmetries of Bravais lattices higher than the point groups. Here we propose a new method to solve this problem. The shape transforms of nanocrystals can be determined from all of the intensities around the diffraction spots, and then Fourier transformation of a single crystal cell is obtained. The actual orientations of the patterns can be solved by comparing the values of the Fourier transformations of the crystal cell on the intersections of all patterns. This so-called ＂multiple-common-line＂ method can distinguish the twin orientations in the XFEL diffraction patterns successfully.