Novel Stereoselective Synthesis of 1,3-Dienyl Tellurides by Palladium Catalyzed Cross-coupling Reaction of (E)-β--Bromovinyl Tellurides

β-Bromovinyl tellurides are new difuctional reagents which undergo palladium-catalyzed cross-coupling reaction with alkenes to give conjugated dienyl tellurides.

PALLADIUM CATALYZED REACTION OF 3-TRIMETHYLSILYLPROPARGYLIC CARBONATES WITH DINUCLEOPHILES

Methyl 3-trimethylsilylpropargyl carbonate reacted with dinucleophiles under the catalysis of palladium(0) complex to give the corresponding desilylated annulation products.

A Novel Palladium-Catalyzed Reaction and Its Application in Preparation of Derivatives of Stilbazols

A novel palladium-catalyzed coupling reaction for the preparation of derivatives of stilbazoles was presented. A series of stilbazoles were synthesized firstly by this highly efficient method. From this reaction it was found that reaction solvent is one of important factors in this catalytic system.

SOLID-LIQUID PHASE TRANSFER AND COBALT OR PALLADIUM COMPLEX CATALYZED SYNTHESIS OF ANHYDRIDES FROM ACYL CHLORIDES

Acyl chloride can efficiently be converted into anhydride under solid liquid phase transfer catalysis by using bis(triphenylphosphine)cobalt dichloride or bis(triphenylphospine)palladium dichloride as the catalyst.

Pd-catalyzed asymmetric carbonyl alkynylation:Synthesis of axial chiral ynones

Ynones are important skeletons in bioactive molecules and valuable building blocks for organic synthesis,thus great efforts have been devoted to their preparation.While,introducing prochiral substrates to construct ynones bearing a chiral framework is unrealized to date.Herein,we reported the first example of Pd/SOP-catalyzed asymmetric carbonylative alkynylation via a non-classical carbonylative Sonogashiratype approach(acyl-Pd(Ⅱ)species generated from nucleophiles).By using cyclic diaryliodonium salts as prochiral substrates,various axial chiral ynones with good functional group tolerance(39 examples),satisfied yields(71%-96%)and excellent enantioselectivities(generally 94%-99%ee)were produced.Synthesis of bioactive compounds,scale-up experiment and useful transformations were also conducted to demonstrate the utility of this process.

Chlorodifluoromethane triggered formation of difluoromethylated arenes catalyzed by palladium

Subject Code:B02With the support by the National Natural Science Foundation of China,a study by the research group led by Prof.Zhang Xingang（张新刚）from the Institute of Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences demonstrates the first direct catalytic difluoromethylations from ClCF2H,

Pd（0）-Catalyzed Tandem One-Pot Reaction of Biphenyl Ketones/Aldehydes to the Corresponding Di-substituted Aryl Olefins

Synthesis of di-substituted aryl olefins via a Pd（0）-catalyzed cross-coupling reaction of biphenyl ketones/alde- hydes, tosylhydrazide, and aryl bromides （or benzyl halides） was developed. This methodology was achieved by one-pot two-step reactions involving the preparation of N-tosylhydrazones by reacting tosylhydrazide with biphenyl ketones/aldehydes, followed by coupling with aryl bromides （or benzyl halides） in the presence of Pd（PPh3）4 and lithium t-butoxide to produce various di-substituted aryl olefins in moderate to good yields.

Selective hydrogenation of unprotected indole to indoline over N-doped carbon supported palladium catalyst

Mesoporous N-doped carbon supported palladium catalyst Pd@CN0.132 was able to efficiently catalyze unprotected indole to indoline under mild conditions.In the aqueous system,a selectivity of 100% and conversion of 96% was achieved under 313 K and atmospheric hydrogen gas.

New synthetic approach for the preparation of 2-aryl-thiazolo[4,5-b]pyridines via Liebeskind–Srogl reaction

The potentially bioactive 2-aryl-thiazolo[4,5-b]pyridines were synthesized via palladium-catalyzed desulfitative cross-coupling reaction between multisubstituted thiazolo[4,5-b]pyridine thioethers and boronic acids. Yields of 48%–94% were obtained with copper（I） thiophene-2-carboxylate in the system.

Highly regioselective hydroformylation of olefins with formic acid instead of toxic and flammable CO/H2

Hydroformylation is an atom-economic and highly efficient transformation from readily available olefins to various synthetically important carbonyl compounds[1].By using this transformation,the largest amount of fine chemicals have been produced in the global chemical industry every year.