Paradoxical herniation associated with hyperbaric oxygen therapy after decompressive craniectomy: A case report

BACKGROUND Whether hyperbaric oxygen therapy(HBOT)can cause paradoxical herniation is still unclear.CASE SUMMARY A 65-year-old patient who was comatose due to brain trauma underwent decompressive craniotomy and gradually regained consciousness after surgery.HBOT was administered 22 d after surgery due to speech impairment.Paradoxical herniation appeared on the second day after treatment,and the patient’s condition worsened after receiving mannitol treatment at the rehabilitation hospital.After timely skull repair,the paradoxical herniation was resolved,and the patient regained consciousness and had a good recovery as observed at the follow-up visit.CONCLUSION Paradoxical herniation is rare and may be caused by HBOT.However,the underlying mechanism is unknown,and the understanding of this phenomenon is insufficient.The use of mannitol may worsen this condition.Timely skull repair can treat paradoxical herniation and prevent serious complications.

Multiple paradoxical embolisms caused by central venous catheter thrombus passing through a patent foramen ovale: A case report

BACKGROUND To date,this is the first case of a paradoxical embolism(PDE)that concurrently manifested in the coronary and lower limb arteries and was secondary to a central venous catheter(CVC)thrombus via a patent foramen ovale(PFO).CASE SUMMARY Here,we report a case of simultaneous coronary and lower limb artery embolism in a PFO patient carrier of a CVC.The patient presented to the hospital with acute chest pain and lower limb fatigue.Doppler ultrasound showed a large thrombus in the right internal jugular vein,precisely at the tip of the CVC.Transthoracic and transesophageal echocardiography confirmed the existence of a PFO,with inducible right-to-left shunting by the Valsalva maneuver.The patient was administered an extended course of anticoagulation therapy,and then the CVC was successfully removed.Percutaneous PFO closure was not undertaken.There was no recurrence during follow-up.CONCLUSION Thus,CVC-associated thrombosis is a potential source for multiple PDE in PFO patients.

COVID-19 mortality paradox(United States vs Africa):Mass vaccination vs early treatment

The coronavirus disease 2019(COVID-19)mortality rate in 55 African countries is almost 4.5 times lower than in the coronavirus disease 2019(COVID-19)despite Africa having over 4.2 times more people.This mortality paradox is also evident when comparing Nigeria,a heavily populated,poorly vaccinated and weakly mandated country to Israel,a small,highly vaccinated and strictly mandated country.Nigeria has almost 4 times lower COVID mortality than Israel.In this Field of Vision perspective,I explain how this paradox has evolved drawing upon my academic,clinical and social experience.Since April 2020,I’ve developed and been using the Egyptian immune-modulatory Kelleni’s protocol to manage COVID-19 patients including pediatric,geriatric,pregnant,immune-compromised and other individuals suffering from multiple comorbidities.It’s unfortunate that severe acute respiratory syndrome coronavirus 2 is still evolving accompanied by more deaths.However in Africa,we’ve been able to live without anxiety or mandates throughout the pandemic because we trust science and adopted early treatment using safe,and effective repurposed drugs that have saved the majority of COVID-19 patients.This article represents an African and Egyptian tale of honor.

The AI Paradox: Mapping the Unintended Disruptions in IT and Beyond

In the realm of Artificial Intelligence (AI), there exists a complex landscape where promises of efficiency and innovation clash with unforeseen disruptions across Information Technology (IT) and broader societal realms. This paper sets out on a journey to explore the intricate paradoxes inherent in AI, focusing on the unintended consequences that ripple through IT and beyond. Through a thorough examination of literature and analysis of related works, this study aims to shed light on the complexities surrounding the AI paradox. It delves into how this paradox appears in various domains, such as algorithmic biases, job displacement, ethical dilemmas, and privacy concerns. By mapping out these unintended disruptions, this research seeks to offer a nuanced understanding of the challenges brought forth by AI-driven transformations. Ultimately, its goal is to pave the way for the responsible development and deployment of AI, fostering a harmonious integration of technological progress with societal values and priorities.

Solving the Olbers’s Paradox, Explaining the “Red-Shift”, and Challenging the Relativities by “Sun Matters Theory” and “Sun Model of Universe”, an Evolution of the Einstein’s Static Universe Model

Olbers’s paradox, known as the dark night paradox, is an argument in astrophysics that the darkness of the night sky conflicts with the assumption of an infinite and eternal static universe. Big-Bang theory was used to partially explain this paradox, while introducing new problems. Hereby, we propose a better theory, named Sun Matters Theory, to explain this paradox. Moreover, this unique theory supports and extended the Einstein’s static universe model proposed by Albert Einstein in 1917. Further, we proposed our new universe model, “Sun Model of Universe”. Based on the new model and novel theory, we generated innovative field equation by upgrading Einstein’s Field Equation through adding back the cosmological constant, introducing a new variable and modifying the gravitationally-related concepts. According to the Sun Model of Universe, the dark matter and dark energy comprise the so-called “Sun Matters”. The observed phenomenon like the red shift is explained as due to the interaction of ordinary light with Sun Matters leading to its energy and frequency decrease. In Sun Model, our big universe consists of many universes with ordinary matter at the core mixed and surrounded with the Sun Matters. In those universes, the laws of physics may be completely or partially different from that of our ordinary universe with parallel civilizations. The darkness of night can be easily explained as resulting from the interaction of light with the Sun Matters leading to the sharp decrease in the light intensity. Sun Matters also scatter the light from a star, which makes it shining as observed by Hubble. Further, there is a kind of Sun Matters named “Sun Waters”, surrounding every starts. When lights pass by the sun, the Sun Waters deflect the lights to bend the light path. According to the Sun Model, it is the light bent not the space bent that was proposed in the theory of relativities.

Twin Paradox and Proper Time

Professors Mohazzbi and Luo [1] published “Despite several attempts have been made to explain the twin paradox … none of the explanations … resolved the paradox. If the paradox can be ever resolved, it requires a much deeper understanding … of the theory of relativity”. The deeper understanding of resolving the paradox is by applying more explicit definitions of proper time interval, Lorentz transform, time dilation, and aging time.

Paradoxical roles of inhibitory autapse and excitatory synapse in formation of counterintuitive anticipated synchronization

Different from the common delayed synchronization(DS)in which response appears after stimulation,anticipated synchronization(AS)in unidirectionally coupled neurons denotes a counterintuitive phenomenon in which response of the receiver neuron appears before stimulation of the sender neuron,showing an interesting function of brain to anticipate the future.The dynamical mechanism for the AS remains unclear due to complex dynamics of inhibitory and excitatory modulations.In this article,the paradoxical roles of excitatory synapse and inhibitory autapse in the formation of AS are acquired.Firstly,in addition to the common roles such that inhibitory modulation delays and excitatory modulation advances spike,paradoxical roles of excitatory stimulation to delay spike via type-II phase response and of inhibitory autapse to advance spike are obtained in suitable parameter regions,extending the dynamics and functions of the excitatory and inhibitory modulations.Secondly,AS is related to the paradoxical roles of the excitatory and inhibitory modulations,presenting deep understandings to the AS.Inhibitory autapse induces spike of the receiver neuron advanced to appear before that of the sender neuron at first,and then excitatory synapse plays a delay role to prevent the spike further advanced,resulting in the AS as the advance and delay effects realize a dynamic balance.Lastly,inhibitory autapse with strong advance,middle advance,and weak advance and delay effects induce phase drift(spike of the receiver neuron advances continuously),AS,and DS,respectively,presenting comprehensive relationships between AS and other behaviors.The results present potential measures to modulate AS related to brain function.

Paradoxical vocal fold motion masquerading as post-anesthetic respiratory distress:A case report

BACKGROUND Functional vocal cord disorders can be a differential diagnosis for postoperative upper airway obstruction requiring urgent intervention.However,this may be unfamiliar to anesthesiologists who would favor inappropriate airway intervention and increased morbidity.CASE SUMMARY A 61-year-old woman underwent cervical laminectomy,followed by laparoscopic cholecystectomy 10 mo later.Despite adequate reversal of neuromuscular blockade,the patient experienced repetitive respiratory difficulty with inspiratory stridor after extubation.After the second operation,the patient was diagnosed with paradoxical vocal fold motion(PVFM)by an otolaryngologist based on the clinical features and fiberoptic bronchoscopy results,and the patient was successfully treated.CONCLUSION PVFM should be considered a differential diagnosis if a patient presents with stridor after general anesthesia.

Probability Distributions Arising in Connection with the Inspection Paradox for Bernoulli Trials

In renewal theory, the Inspection Paradox refers to the fact that an interarrival period in a renewal process which contains a fixed inspection time tends to be longer than one for the corresponding uninspected process. We focus on the paradox for Bernoulli trials. Probability distributions and moments for the lengths of the interarrival periods are derived for the inspected process, and we compare them to those for the uninspected case.

Probability Distributions Arising in Connection with the Inspection Paradox for the Poisson Process

The Inspection Paradox refers to the fact that in a Renewal Process, the length of the interarrival period which contains a fixed time is stochastically larger than the length of a typical interarrival period. To provide a more complete understanding of this phenomenon, conditioning arguments are used to obtain the distributions and moments of the lengths of the interarrival periods other than the one containing this fixed time for the case of the time-homogeneous Poisson Process. Distributions of the waiting times for events that occur both before and after this fixed time are derived. This provides a fairly complete probabilistic analysis of the Inspection Paradox.

Resolving the Information Paradox with Probabilistic Spacetime

It has been 50 years since Hawking described the black hole (BH) information paradox. The combination of BH radiation and subsequent BH evaporation was found to take trapped information into oblivion contrary to the law of conservation of quantum information. Numerous attempts have been made since to resolve this paradox. A brief review herein documents how all these attempts have significant shortcomings, meaning the paradox is still unresolved. A relatively new cosmological theory offers a resolution despite not being developed for that purpose. The theory, entitled the probabilistic spacetime theory (PST), starts with an alteration in one basic assumption compared to all current cosmological theories. Spacetime, instead of being seen as a void or container of other entities, is viewed as the most fundamental entity in the universe, composed of energy fragments, and (in keeping with the conservation principle) impermeable to destruction. The potential contribution of the PST in resolving the information paradox is delineated, with the finding that the single change in the conceptualization of spacetime results in the disappearance of the paradox and not information.

Unbearable suffering obviates euthanasia:definitionally derived set of propositions comprising euthanasia’s purpose,claim,and benefit lead to contradiction establishing the paradox of euthanasia

Relying on euthanasia’s definitionally derived set of propositions to provide its purpose,claims,and benefit,we obtain the core concept.Nonetheless,given its core concept,euthanasia is demonstrated to provide no benefit to the animal to justify its use.Euthanasia 1)cannot possibly,and therefore does not,end unbearable suffering,2)it fails to hasten death,and 3)it,therefore,provides no perceptible relief to the patient.These findings are significant because the argument’s validity does not permit euthanasia to satisfy its definitionally derived purpose,claims,or benefit on logical grounds.In other words,the argument is that as a form of legalized assisted suicide,euthanasia is wrong but not in the way principled arguments would suggest.Additionally,irrespective of euthanasia actually doing what it claims,if it is allowed to be provisioned,then euthanasia will affect vulnerable populations exactly like nonprincipled arguments claim.Therefore,despite sharing aspects with each type of argument in the extant literature,my argument against euthanasia can be categorized as neither principled nor nonprincipled,which makes it significant because it may be the first of a new category of argument against the concept and practice to enter the discourse on euthanasia.As a corollary,since we prove that unbearable suffering logically entails death,when it is authentic signifying that death is imminent,because euthanasia’s only purpose is to end unbearable suffering by inducing death,euthanasia is completely obviated.

莎剧中的Paradox修辞及其汉译

Paradox是将两个意义对立的概念置于一处,看起来"非"实际上"是"的一种修辞手法,在莎士比亚戏剧中起着至关重要的作用。本文以莎士比亚四大悲剧为语料来源,采用较为简洁、清晰的方法,将paradox分为单词相对、短语相对和句子相对3种形式,并参照"辞格翻译方法模型",选取梁实秋、朱生豪等5种代表性译本,对paradox在不同译本中的翻译方法进行统计发现:梁实秋、朱生豪等5位译者均倾向于同时保留原文辞格的"修辞格式"和"修辞内容";在对paradox汉译操作的影响上,修辞格式大于修辞内容,辞格的特点大于译者的特点。

莎剧中的Paradox与Oxymoron比较研究

Paradox和oxymoron是两种既有联系又有区别的修辞格,在莎士比亚戏剧中起到至关重要的作用。两种辞格均由两个对立成分组合而成,表面自相矛盾,实则蕴含哲理;区别在于paradox是句子层面的修辞,oxymoron是短语层面的修辞。以《哈姆雷特》《奥赛罗》《麦克白》《罗密欧与朱丽叶》为基本语料来源,全面、系统地比较二者异同,可以发现这两种修辞在构成方式上差异较大,从语法结构层面划分,paradox可分为单词相对、短语相对和句子相对三种形式,oxymoron可分为名词+名词、名词+of+名词、动词+动词、形容词+形容词、形容词+名词、动词+副词六种类型;然而,两种修辞在语义关系和修辞功能上基本类似,即因果、方式、主从和交融关系,均具有强化语言、刻画人物和深化主题的修辞功能。

Paradox数据库稳定运行的解决方案

阐述了C++Builder编程中使用Paradox数据库时经常出现的问题 ,给出了程序中自动解决这些问题的方法及程序示例 .实践表明 ,对于Master/Detail数据库使用动态参数设定的方法初始化数据库中的参数可以避免问题的出现 ,并使数据库的使用更加稳定可靠 .

抗菌药物的“PARADOX效应”及其临床意义

自Fleming发现青霉素及Domagk首次报告百浪多息(Prontosil)具有体内抗感染作用以来,抗菌药物迅速发展,应用日益广泛,在当今感染性疾病的治疗中起着十分重要的作用。目前,判断某种抗菌药的临床应用价值,主要是根据药物的体外抗菌活性。药代动力学参数及其对人体的毒性大小,并倾向认为体内感染病灶中药物浓度的高低是影响药物疗效的决定因素,也是临床选药的依据。但已有资料表明,某些药物的抗菌作用的量效关系呈双相变化,即药物有一最强抗菌浓度范围,当浓度高于此范围时。

"Paradox"修辞格--"反差"中实现的统一

本文从不同的角度,通过一系列的"反差",分析了paradox修辞格是怎样使形式的不和谐统一在内容的深处.

Paradox数据库数据读取的实现

Paradox数据库是一种关系型网络数据库,数据格式比较复杂,对该数据库中数据的读取,是一个技术难题,笔者给出了一种读取方法,并用C#语言给出了相应的实现程序.

Paradox of Happiness Gene——An Analysis of Power’s Ethical Thoughts in Generosity: An Enhancement

Generosity:An Enhancement revolving around Thassadit Amzwar and the happiness gene in her body, concentrates on its appearance,research, publicity and exploiting of her happiness gene. It proposes the ethical conundrums: Are negative emotions like depression and anxiety no longer needed? Can a genetic marker dispose us toward happiness? Happiness should not be left to contingency and genes.Once materialized into a physical object which can be bought and sold like a commodity,the fundamental laws of ethics will collapse.

Paradoxes in Isabel Archer's View of Freedom in The Portrait of a Lady

In The Portrait of a Lady, Isabel Archer values her liberty higher than a sense of security that might be guaranteed by possessing great fortune. But there are some paradoxes in Isabel Archer's view of freedom, which have caused her failure in the fulfillment of her view of freedom.