The parallel-plate flow chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in vitro study of the mechanical behaviors of cultured cells at the bottom...The parallel-plate flow chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in vitro study of the mechanical behaviors of cultured cells at the bottom of PPFC undergoing shear stress. The PPFC of which the upper and lower plates are rectangular is usually used by research workers, and the flow field in this kind of PPFC (except for the regions near the entrance and exit) is uniform([1]), so only the effect the shear stress with one value has on cultured cells can be observed during each experiment. A kind of PPFC of which the upper and lower plates are not rectangular is proposed in this paper. The distributions of the velocities inside and the shear stresses at the bottom of the chamber are given by analyzing the flow field of the steady flow in the PPFC. The results show that the mechanical behaviors of cultured cells undergoing the shear stresses with various values may be simultaneously observed by the use of this kind of irrectangular PPFC. The theoretical and experimental results obtained by Ultrasonic Doppler Technique show good agreement.展开更多
The Parallel-Plate Flow Chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in-vitro study of the mechanical behavior of cultured vascular Endotheli...The Parallel-Plate Flow Chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in-vitro study of the mechanical behavior of cultured vascular Endothelical Cells (ECs) exposed to fluid shear stress. The steady flow in different kinds of PPFC has been extensively investigated, whereas, the pulsatile flow in the PPFC has received little attention. In consideration of the characteristics of geometrical size and pulsatile flow in the PPFC, the 3-D pulsatile flow was decomposed into a 2-D pulsatile flow in the vertical plane, and an incompressible plane potential flow in the horizontal plane. A simple method was then proposed to analyze the pulsatile flow in the PPFC with spatial shear stress gradient. On the basis of the method, the pulsatile fluid shear stresses in several reported PPFCs with spatial shear stress gradients were calculated. The results were theoretically meaningful for applying the PPFCs in-vitro, to simulate the pulsatile fluid shear stress environment, to which cultured ECs were exposed.展开更多
Many in vitro studies focus on effects of wall shear stress (WSS) and wall shear stress gradient (WSSG) on endothelial cells, which are linked to the initiation and progression of atherosclerosis in the arterial syste...Many in vitro studies focus on effects of wall shear stress (WSS) and wall shear stress gradient (WSSG) on endothelial cells, which are linked to the initiation and progression of atherosclerosis in the arterial system. Limitation in available flow chambers with a constant WSSG in the testing region makes it difficult to quantify cellular responses to WSSG. The current study proposes and characterizes a type of converging parallel plate flow chamber (PPFC) featuring a constant gradient of WSS. A simple formula was derived for the curvature of side walls, which relates WSSG to flow rate (Q), height of the PPFC (h), length of the convergent section (L), its widths at the entrance (w0) and exit (w1). CFD simulation of flow in the chamber is carried out. Constant WSSG is observed in most regions of the top and bottom plates except those in close proximity of side walls. A change in Q or h induces equally proportional changes in WSS and WSSG whereas an alteration in the ratio between w0 and w1 results in a more significant change in WSSG than that in WSS. The current design makes possible an easy quantification of WSSG on endothelial cells in the flow chamber.展开更多
The downstream water-air heat and moisture transfer system in a moving coordinate was studied. The relationship between the diameter of the misted droplets and the spray pressure was determined. Based on the theory of...The downstream water-air heat and moisture transfer system in a moving coordinate was studied. The relationship between the diameter of the misted droplets and the spray pressure was determined. Based on the theory of the relative velocity,the two-phase flow mode of the spray chamber and the efficiency equation for heat and moisture exchange were established. Corrections were carried out for the efficiency equation with spray pressure of 157 kPa. The results show that the pressure plays an important part in determining the efficiency of heat and moisture exchange. When the spray pressure is less than 157 kPa,better coincidence is noticed between the theoretical analysis and the test results with the error less than 6%. Greater error will be resulted in the case when the spray pressure is beyond 157 kPa. After the correction treatment,the coincidence between the theoretical and the experimental results is greatly improved.展开更多
To improve the performance of the Stairmand cyclone, the effects of an expansion chamber on the flow field, the pressure drop and the separation efficiency were investigated numerically and experimentally. The experim...To improve the performance of the Stairmand cyclone, the effects of an expansion chamber on the flow field, the pressure drop and the separation efficiency were investigated numerically and experimentally. The experimental results showed that compared with the Stairmand cyclone, the cyclone with an upper expansion chamber worked better at low inlet velocity(less than 14 m/s in this study), while the cyclone with a lower expansion chamber achieved higher efficiency at a relatively high inlet velocity(14-20 m/s). The presence of an expansion chamber can generally result in a slight decrease in the cyclone pressure drop. The simulated results, which were used to further analyze the reason behind the experimental phenomena, suggested that the expansion chamber had insignificant effects on the tangential velocity profiles in the cylindrical part of cyclones. While in the cone part, the expansion chamber and the dipleg, the tangential velocity slightly decreased. Nevertheless, the expansion chamber decreased the possibility of the vortex end to sweep the wall and then reduce the particle re-entrainment. Therefore, installing the expansion chamber at a proper position could improve the separation performance of Stairmand cyclones. Both the experimental and simulated results represent a potential improvement of the Stairmand cyclone performance.展开更多
An improved model to calculate the length of the mixing chamber of the ejector was proposed on the basis of the Fano flow model,and a method to optimize the structures of the mixing chamber and diffuser of the ejector...An improved model to calculate the length of the mixing chamber of the ejector was proposed on the basis of the Fano flow model,and a method to optimize the structures of the mixing chamber and diffuser of the ejector was put forward.The accuracy of the model was verified by comparing the theoretical results calculated using the model to experimental data reported in literature.Variations in the length of the mixing chamber L_(m) and length of the diffuser L_(d) with respect to variations in the outlet temperature of the ejector T_(c),outlet pressure of the ejector p_(c),and the expansion ratio of the pressure of the primary flow to that of the secondary flow p_(g)/p_(e) were investigated.Moreover,variations in L_(m) and L_(d) with respect to variations in the ratio of the diameter of the throat of the motive nozzle to the diameter of the mixing chamber d_(g0)/d_(c3) and ratio of the outlet diameter of the diffuser to the diameter of themixing chamber d_(c)/d_(c3) were investigated.The distribution of flow fields in the ejector was simulated.Increasing L_(m) and d_(c3) reduced T_(c) and p_(c).Moreover,reducing p_(g)/p_(e) or d_(g0)/d_(c3) reduced T_(c) and p_(c).The length of the mixed section L_(m2),which was determined on the basis of the Fano flow model,increased as pg increased and decreased as d_(c3) increased.The mixing length L_(m1),which was considered the primary flow expansion,showed the opposite trend with that of L_(m2).Moreover,Ld increased as p_(g)/p_(e) and d_(c)/d_(c3) increased.When the value of d_(c) was 1.8 to 2.0 times as high as that of dc3,the semi-cone angle of the diffuser ranged between 6°and 12°.At a constant dc/dc3,decreasing T_(c) and pc increased Ld.展开更多
Introduction Blood flow provides a mechanical condition for blood cells and vessels,especially for endothelial cells.It is important to understand the mechanical characteristics of
Ethylene cracking process is the core production process in ethylene industry,and is paid more attention to reduce high energy consumption.Because of the interdependent relationships between multi-flow allocation and ...Ethylene cracking process is the core production process in ethylene industry,and is paid more attention to reduce high energy consumption.Because of the interdependent relationships between multi-flow allocation and multi-parameter setting in cracking process,it is difficult to find the overall energy efficiency scheduling for the purpose of saving energy.The traditional scheduling solutions with optimal economic benefit are not applicable for energy efficiency scheduling issue due to the neglecting of recycle and lost energy,as well as critical operation parameters as coil outlet pressure(COP)and dilution ratio.In addition,the scheduling solutions mostly regard each cracking furnace as an elementary unit,regardless of the coordinated operation of internal dual radiation chambers(DRC).Therefore,to improve energy utilization and production operation,a novel energy efficiency scheduling solution for ethylene cracking process is proposed in this paper.Specifically,steam heat recycle and exhaust heat loss are considered in cracking process based on 6 types of extreme learning machine(ELM)based cracking models incorporating DRC operation and three operation parameters as coil outlet temperature(COT),COP,and dilution ratio according to semi-mechanism analysis.Then to provide long-term decision-making basis for energy efficiency scheduling,overall energy efficiency indexes,including overall output per unit net energy input(OONE),output-input ratio per unit net energy input(ORNE),exhaust gas heat loss ratio(EGHL),are designed based on input-output analysis in terms of material and energy flows.Finally,a multiobjective evolutionary algorithm based on decomposition(MOEA/D)is employed to solve the formulated multi-objective mixed-integer nonlinear programming(MOMINLP)model.The validities of the proposed scheduling solution are illustrated through a case study.The scheduling results demonstrate that an optimal balance between multi-flow allocation,multi-parameter setting,and DRC coordinated operation is reached,which achieves 3.37%and 2.63%decreases in net energy input for same product output and conversion ratio,as well as the 1.56%decrease in energy loss ratio.展开更多
New designs and adaptation methods are experimented to ensure compliance to ever increasing emissions and efficiency requirements of modern diesel engines. Piston head structure which influences the mixing rate and ti...New designs and adaptation methods are experimented to ensure compliance to ever increasing emissions and efficiency requirements of modern diesel engines. Piston head structure which influences the mixing rate and timing of the fuel within in the combustion chamber is known to enable increase in combustion efficiency and thus lower emission rates. In this paper, computation analysis of flow within a diesel engine cylinder with a twin swirl combustion chamber design throughout a full cycle is presented. The results obtained indicate that the effect of the twin swirl combustion chamber on the cold flow conditions is noteworthy and further analysis together with experiments may reveal information that may prove to be useful in further new designs.展开更多
Due to the inherent working mode of rotating detonation engine(RDE),the detonation flow field has the characteristics of pressure oscillation and axial kinetic energy loss,which makes it difficult to design nozzle and...Due to the inherent working mode of rotating detonation engine(RDE),the detonation flow field has the characteristics of pressure oscillation and axial kinetic energy loss,which makes it difficult to design nozzle and improve propulsion performance.Therefore,in order to improve the characteristics of detonation flow field,the three-dimensional numerical simulation of annular chamber and hollow chamber is carried out with premixed hydrogen/air as fuel in this paper,and then tries to combine the two chambers to weaken the oscillation characteristics of detonation flow field through the interaction of detonation flow field,which is a new method to regulate the detonation flow field.The results show that there are four states of velocity vectors at the outlet of annular chamber and hollow chamber,which makes RDE be affected by rolling moment and results in the loss of axial kinetic energy.In the external flow field of combined chamber,the phenomenon of cyclic reflection of expansion wave and compression wave on the free boundary is observed,which results in Mach disk structure.Moreover,the pressure monitoring points are set at the external flow field.The pressure signal shows that the high-frequency pressure oscillation at the external flow field of the combined chamber has been greatly weakened.Compared to the annular chamber,the relative standard deviation(RSD) has been reduced from 14.6% to5.6%.The results thus demonstrate that this method is feasible to adjust the pressure oscillation characteristics of the detonation flow field,and is of great significance to promote the potential of RDE and nozzle design.展开更多
文摘The parallel-plate flow chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in vitro study of the mechanical behaviors of cultured cells at the bottom of PPFC undergoing shear stress. The PPFC of which the upper and lower plates are rectangular is usually used by research workers, and the flow field in this kind of PPFC (except for the regions near the entrance and exit) is uniform([1]), so only the effect the shear stress with one value has on cultured cells can be observed during each experiment. A kind of PPFC of which the upper and lower plates are not rectangular is proposed in this paper. The distributions of the velocities inside and the shear stresses at the bottom of the chamber are given by analyzing the flow field of the steady flow in the PPFC. The results show that the mechanical behaviors of cultured cells undergoing the shear stresses with various values may be simultaneously observed by the use of this kind of irrectangular PPFC. The theoretical and experimental results obtained by Ultrasonic Doppler Technique show good agreement.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 10472027, 30670511).
文摘The Parallel-Plate Flow Chamber (PPFC), of which the height is far smaller than its own length and width, is one of the main apparatus for the in-vitro study of the mechanical behavior of cultured vascular Endothelical Cells (ECs) exposed to fluid shear stress. The steady flow in different kinds of PPFC has been extensively investigated, whereas, the pulsatile flow in the PPFC has received little attention. In consideration of the characteristics of geometrical size and pulsatile flow in the PPFC, the 3-D pulsatile flow was decomposed into a 2-D pulsatile flow in the vertical plane, and an incompressible plane potential flow in the horizontal plane. A simple method was then proposed to analyze the pulsatile flow in the PPFC with spatial shear stress gradient. On the basis of the method, the pulsatile fluid shear stresses in several reported PPFCs with spatial shear stress gradients were calculated. The results were theoretically meaningful for applying the PPFCs in-vitro, to simulate the pulsatile fluid shear stress environment, to which cultured ECs were exposed.
文摘Many in vitro studies focus on effects of wall shear stress (WSS) and wall shear stress gradient (WSSG) on endothelial cells, which are linked to the initiation and progression of atherosclerosis in the arterial system. Limitation in available flow chambers with a constant WSSG in the testing region makes it difficult to quantify cellular responses to WSSG. The current study proposes and characterizes a type of converging parallel plate flow chamber (PPFC) featuring a constant gradient of WSS. A simple formula was derived for the curvature of side walls, which relates WSSG to flow rate (Q), height of the PPFC (h), length of the convergent section (L), its widths at the entrance (w0) and exit (w1). CFD simulation of flow in the chamber is carried out. Constant WSSG is observed in most regions of the top and bottom plates except those in close proximity of side walls. A change in Q or h induces equally proportional changes in WSS and WSSG whereas an alteration in the ratio between w0 and w1 results in a more significant change in WSSG than that in WSS. The current design makes possible an easy quantification of WSSG on endothelial cells in the flow chamber.
基金Project(06YFJMCI5500) supported by the Natural Science Foundation of Tianjin City of China
文摘The downstream water-air heat and moisture transfer system in a moving coordinate was studied. The relationship between the diameter of the misted droplets and the spray pressure was determined. Based on the theory of the relative velocity,the two-phase flow mode of the spray chamber and the efficiency equation for heat and moisture exchange were established. Corrections were carried out for the efficiency equation with spray pressure of 157 kPa. The results show that the pressure plays an important part in determining the efficiency of heat and moisture exchange. When the spray pressure is less than 157 kPa,better coincidence is noticed between the theoretical analysis and the test results with the error less than 6%. Greater error will be resulted in the case when the spray pressure is beyond 157 kPa. After the correction treatment,the coincidence between the theoretical and the experimental results is greatly improved.
基金the financial assistance from the National Natural Science Foundation (Grant No.21276274)the National Key Project of Basic Research of the Ministry for Science and Technology of China (Grant No. 2014CB744304)
文摘To improve the performance of the Stairmand cyclone, the effects of an expansion chamber on the flow field, the pressure drop and the separation efficiency were investigated numerically and experimentally. The experimental results showed that compared with the Stairmand cyclone, the cyclone with an upper expansion chamber worked better at low inlet velocity(less than 14 m/s in this study), while the cyclone with a lower expansion chamber achieved higher efficiency at a relatively high inlet velocity(14-20 m/s). The presence of an expansion chamber can generally result in a slight decrease in the cyclone pressure drop. The simulated results, which were used to further analyze the reason behind the experimental phenomena, suggested that the expansion chamber had insignificant effects on the tangential velocity profiles in the cylindrical part of cyclones. While in the cone part, the expansion chamber and the dipleg, the tangential velocity slightly decreased. Nevertheless, the expansion chamber decreased the possibility of the vortex end to sweep the wall and then reduce the particle re-entrainment. Therefore, installing the expansion chamber at a proper position could improve the separation performance of Stairmand cyclones. Both the experimental and simulated results represent a potential improvement of the Stairmand cyclone performance.
文摘An improved model to calculate the length of the mixing chamber of the ejector was proposed on the basis of the Fano flow model,and a method to optimize the structures of the mixing chamber and diffuser of the ejector was put forward.The accuracy of the model was verified by comparing the theoretical results calculated using the model to experimental data reported in literature.Variations in the length of the mixing chamber L_(m) and length of the diffuser L_(d) with respect to variations in the outlet temperature of the ejector T_(c),outlet pressure of the ejector p_(c),and the expansion ratio of the pressure of the primary flow to that of the secondary flow p_(g)/p_(e) were investigated.Moreover,variations in L_(m) and L_(d) with respect to variations in the ratio of the diameter of the throat of the motive nozzle to the diameter of the mixing chamber d_(g0)/d_(c3) and ratio of the outlet diameter of the diffuser to the diameter of themixing chamber d_(c)/d_(c3) were investigated.The distribution of flow fields in the ejector was simulated.Increasing L_(m) and d_(c3) reduced T_(c) and p_(c).Moreover,reducing p_(g)/p_(e) or d_(g0)/d_(c3) reduced T_(c) and p_(c).The length of the mixed section L_(m2),which was determined on the basis of the Fano flow model,increased as pg increased and decreased as d_(c3) increased.The mixing length L_(m1),which was considered the primary flow expansion,showed the opposite trend with that of L_(m2).Moreover,Ld increased as p_(g)/p_(e) and d_(c)/d_(c3) increased.When the value of d_(c) was 1.8 to 2.0 times as high as that of dc3,the semi-cone angle of the diffuser ranged between 6°and 12°.At a constant dc/dc3,decreasing T_(c) and pc increased Ld.
基金supported by grant from National Natural Science Foundation of China No10772127,30570450Program for New Century Excellent Talents in University NCET-06-0789Sichaun Youth Science and Technology Foundation 06ZQ026-009
文摘Introduction Blood flow provides a mechanical condition for blood cells and vessels,especially for endothelial cells.It is important to understand the mechanical characteristics of
基金supported by the High-tech Research and Development Program of China(2014AA041802)。
文摘Ethylene cracking process is the core production process in ethylene industry,and is paid more attention to reduce high energy consumption.Because of the interdependent relationships between multi-flow allocation and multi-parameter setting in cracking process,it is difficult to find the overall energy efficiency scheduling for the purpose of saving energy.The traditional scheduling solutions with optimal economic benefit are not applicable for energy efficiency scheduling issue due to the neglecting of recycle and lost energy,as well as critical operation parameters as coil outlet pressure(COP)and dilution ratio.In addition,the scheduling solutions mostly regard each cracking furnace as an elementary unit,regardless of the coordinated operation of internal dual radiation chambers(DRC).Therefore,to improve energy utilization and production operation,a novel energy efficiency scheduling solution for ethylene cracking process is proposed in this paper.Specifically,steam heat recycle and exhaust heat loss are considered in cracking process based on 6 types of extreme learning machine(ELM)based cracking models incorporating DRC operation and three operation parameters as coil outlet temperature(COT),COP,and dilution ratio according to semi-mechanism analysis.Then to provide long-term decision-making basis for energy efficiency scheduling,overall energy efficiency indexes,including overall output per unit net energy input(OONE),output-input ratio per unit net energy input(ORNE),exhaust gas heat loss ratio(EGHL),are designed based on input-output analysis in terms of material and energy flows.Finally,a multiobjective evolutionary algorithm based on decomposition(MOEA/D)is employed to solve the formulated multi-objective mixed-integer nonlinear programming(MOMINLP)model.The validities of the proposed scheduling solution are illustrated through a case study.The scheduling results demonstrate that an optimal balance between multi-flow allocation,multi-parameter setting,and DRC coordinated operation is reached,which achieves 3.37%and 2.63%decreases in net energy input for same product output and conversion ratio,as well as the 1.56%decrease in energy loss ratio.
文摘New designs and adaptation methods are experimented to ensure compliance to ever increasing emissions and efficiency requirements of modern diesel engines. Piston head structure which influences the mixing rate and timing of the fuel within in the combustion chamber is known to enable increase in combustion efficiency and thus lower emission rates. In this paper, computation analysis of flow within a diesel engine cylinder with a twin swirl combustion chamber design throughout a full cycle is presented. The results obtained indicate that the effect of the twin swirl combustion chamber on the cold flow conditions is noteworthy and further analysis together with experiments may reveal information that may prove to be useful in further new designs.
文摘Due to the inherent working mode of rotating detonation engine(RDE),the detonation flow field has the characteristics of pressure oscillation and axial kinetic energy loss,which makes it difficult to design nozzle and improve propulsion performance.Therefore,in order to improve the characteristics of detonation flow field,the three-dimensional numerical simulation of annular chamber and hollow chamber is carried out with premixed hydrogen/air as fuel in this paper,and then tries to combine the two chambers to weaken the oscillation characteristics of detonation flow field through the interaction of detonation flow field,which is a new method to regulate the detonation flow field.The results show that there are four states of velocity vectors at the outlet of annular chamber and hollow chamber,which makes RDE be affected by rolling moment and results in the loss of axial kinetic energy.In the external flow field of combined chamber,the phenomenon of cyclic reflection of expansion wave and compression wave on the free boundary is observed,which results in Mach disk structure.Moreover,the pressure monitoring points are set at the external flow field.The pressure signal shows that the high-frequency pressure oscillation at the external flow field of the combined chamber has been greatly weakened.Compared to the annular chamber,the relative standard deviation(RSD) has been reduced from 14.6% to5.6%.The results thus demonstrate that this method is feasible to adjust the pressure oscillation characteristics of the detonation flow field,and is of great significance to promote the potential of RDE and nozzle design.