Traditional risk factors for cardiovascular disease can only assess risks for groups of people. New parameters of arterial stiffness are more reliable for predicting cardiovascular outcomes for individuals with and wi...Traditional risk factors for cardiovascular disease can only assess risks for groups of people. New parameters of arterial stiffness are more reliable for predicting cardiovascular outcomes for individuals with and without a cardiovascular history. The objective of this study was to assess the effects of Magnesium-EDTA chelation therapy using new methods and parameters such as pulse wave velocity (PWV), central blood pressure (SBPao) and endothelial function (Aix). We followed 43 patients with an abnormal PWV and SBPao, setting them up in two groups. The 21 patients in Group A had already been diagnosed with cardiovascular disease. The other 22 patients in Group B also showed abnormal PWV, SBPao and Aix, but showed no cardiovascular symptoms. Each patient in Groups A and B received one Mg-EDTA treatment per week. The total treatment plan consisted of 25 Mg-EDTA chelation treatments according to the standard protocol of IBCMT. After 25 Mg-EDTA chelation sessions, PWV and SBPao improved significantly in all patients of Groups A and B. In addition, Aix improved significantly in these patients, but remained abnormal. Group C included 18 asymptomatic patients with normal PWV or SBPao. Aix was abnormal in this group, but to a much lesser extent than Groups A and B. The 18 asymptomatic patients of Group C did not receive Mg-EDTA treatment. Observation showed no significant changes in all three parameters of arterial stiffness. The results of this study indicate that a course of treatment with Magnesium-EDTA chelation therapy significantly lowers cardiovascular risks. We conclude that Mg-EDTA chelation therapy improves PWV as an indicator of arterial stiffness, SBPao (central blood pressure) as an indicator of aortic elasticity and Aix (augmented aortic index) as an indicator of endothelial functioning. These improvements in PWV, SBPao and Aix demonstrate that atherosclerosis is a dynamic and (partially) reversible process.展开更多
目的探析正常高值血压与理想血压飞行员血管无创检测指标之间的关系。方法分理想血压组111例,正常高值血压组99例,先后使用Omron动脉硬化检测仪和Sphygmo Cor无创心功能检测仪采集中心动脉压(central aortic systolic pressure,CA SP...目的探析正常高值血压与理想血压飞行员血管无创检测指标之间的关系。方法分理想血压组111例,正常高值血压组99例,先后使用Omron动脉硬化检测仪和Sphygmo Cor无创心功能检测仪采集中心动脉压(central aortic systolic pressure,CA SP)、心率75次/min时标准反射波增强指数(AIx HR75)、肱踝动脉脉搏波传导速度(brachial-ankle pulse wave velocity,ba PWV)和踝臂指数(ankle-brachial index,A BI)。结果 ①正常高值组baPWV、CASP、AIx H R75均高于理想血压组,差异有统计学意义(P〈0.05);②组A BI比较差异无统计学意义(P〉0.05)。baPWV增快的比例为7.4%。2CASP分布范围在80~120 mm Hg,P50为100 mm Hg,P95为112 mm Hg。③中心动脉血压与外周血压差值分布范围在7~31 mm Hg,P50为18 mm Hg,P95为24 mm Hg;基本呈正态分布。结论正常高值血压与理想血压人群的血管指标差异有统计学意义,但其与临床意义是否对等尚需进一步大样本的研究;CASP应作为评估高血压病的诊断与治疗的指标之一。展开更多
文摘Traditional risk factors for cardiovascular disease can only assess risks for groups of people. New parameters of arterial stiffness are more reliable for predicting cardiovascular outcomes for individuals with and without a cardiovascular history. The objective of this study was to assess the effects of Magnesium-EDTA chelation therapy using new methods and parameters such as pulse wave velocity (PWV), central blood pressure (SBPao) and endothelial function (Aix). We followed 43 patients with an abnormal PWV and SBPao, setting them up in two groups. The 21 patients in Group A had already been diagnosed with cardiovascular disease. The other 22 patients in Group B also showed abnormal PWV, SBPao and Aix, but showed no cardiovascular symptoms. Each patient in Groups A and B received one Mg-EDTA treatment per week. The total treatment plan consisted of 25 Mg-EDTA chelation treatments according to the standard protocol of IBCMT. After 25 Mg-EDTA chelation sessions, PWV and SBPao improved significantly in all patients of Groups A and B. In addition, Aix improved significantly in these patients, but remained abnormal. Group C included 18 asymptomatic patients with normal PWV or SBPao. Aix was abnormal in this group, but to a much lesser extent than Groups A and B. The 18 asymptomatic patients of Group C did not receive Mg-EDTA treatment. Observation showed no significant changes in all three parameters of arterial stiffness. The results of this study indicate that a course of treatment with Magnesium-EDTA chelation therapy significantly lowers cardiovascular risks. We conclude that Mg-EDTA chelation therapy improves PWV as an indicator of arterial stiffness, SBPao (central blood pressure) as an indicator of aortic elasticity and Aix (augmented aortic index) as an indicator of endothelial functioning. These improvements in PWV, SBPao and Aix demonstrate that atherosclerosis is a dynamic and (partially) reversible process.
文摘目的探析正常高值血压与理想血压飞行员血管无创检测指标之间的关系。方法分理想血压组111例,正常高值血压组99例,先后使用Omron动脉硬化检测仪和Sphygmo Cor无创心功能检测仪采集中心动脉压(central aortic systolic pressure,CA SP)、心率75次/min时标准反射波增强指数(AIx HR75)、肱踝动脉脉搏波传导速度(brachial-ankle pulse wave velocity,ba PWV)和踝臂指数(ankle-brachial index,A BI)。结果 ①正常高值组baPWV、CASP、AIx H R75均高于理想血压组,差异有统计学意义(P〈0.05);②组A BI比较差异无统计学意义(P〉0.05)。baPWV增快的比例为7.4%。2CASP分布范围在80~120 mm Hg,P50为100 mm Hg,P95为112 mm Hg。③中心动脉血压与外周血压差值分布范围在7~31 mm Hg,P50为18 mm Hg,P95为24 mm Hg;基本呈正态分布。结论正常高值血压与理想血压人群的血管指标差异有统计学意义,但其与临床意义是否对等尚需进一步大样本的研究;CASP应作为评估高血压病的诊断与治疗的指标之一。