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Antimicrobial activity of crude extracts prepared from fungal mycelia
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作者 Andriy Synytsya Jutamart Monkai +4 位作者 Roman Bleha Anna Macurkova Tomas Ruml Juhee Ahn Ekachai Chukeatirote 《Asian Pacific Journal of Tropical Biomedicine》 SCIE CAS 2017年第3期257-261,共5页
Objective: To evaluate the in vitro antimicrobial property of three different partitioned extracts(petroleum ether, ethanol and water) prepared from some fungal mycelia.Methods: Seven fungal mycelia were prepared, ini... Objective: To evaluate the in vitro antimicrobial property of three different partitioned extracts(petroleum ether, ethanol and water) prepared from some fungal mycelia.Methods: Seven fungal mycelia were prepared, initially extracted with acidified ethanol(0.2 mol/L HCl in 80% ethanol), yielding the raw crude extracts. The obtained extracts were then further partitioned with petroleum ether(F1), ethanol(F2) and water(F3). All the fractions were tested for antimicrobial activity using the disc diffusion assay.Results: Our data showed that all the fractions could inhibit the testing bacteria.However, the inhibitory activity was found to be dependent on(i) the fungal strains used;(ii) the solvent extracted; and(iii) the testing bacteria assayed. In general, the ethanolic extracts(F2) derived from all fungi displayed highest inhibitory activity against the testing bacteria except for Chaetomium sp.Conclusions: The findings of the present study concluded that the extracts prepared from the fungal mycelia had the bioactive compounds with antibacterial property. This study is a pioneering work and further study should be carried out for development of the new drug leads. 展开更多
关键词 Antimicrobial activity Disc diffusion Fungal mycelia partitioned extracts
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