Wide distribution and broad reactivity are cardinal features of pattern recognition receptors that allow rapid mobiliza-tion of large numbers of effectors to deal with pathogens.However, these features come with signi...Wide distribution and broad reactivity are cardinal features of pattern recognition receptors that allow rapid mobiliza-tion of large numbers of effectors to deal with pathogens.However, these features come with significant baggage as the receptors have been shown to interact with many intra-cellular components, collectively called展开更多
基金supported by the National Institute of Health,and National Natural Science Foundation of China (Grant No. 30640420558)
文摘Wide distribution and broad reactivity are cardinal features of pattern recognition receptors that allow rapid mobiliza-tion of large numbers of effectors to deal with pathogens.However, these features come with significant baggage as the receptors have been shown to interact with many intra-cellular components, collectively called