The acute effect of acupuncture on Alzheimer＇s disease,i.e.,on brain activation during treatment,has been reported.However,the effect of long-term acupuncture on brain activation in Alzheimer＇s disease is unclear.Th...The acute effect of acupuncture on Alzheimer＇s disease,i.e.,on brain activation during treatment,has been reported.However,the effect of long-term acupuncture on brain activation in Alzheimer＇s disease is unclear.Therefore,in this study,we performed long-term needling at Zusanli（ST36）or a sham point（1.5 mm lateral to ST36）in a rat Alzheimer＇s disease model,for 30 minutes,once per day,for 30 days.The rats underwent 18F-fluorodeoxyglucose positron emission tomography scanning.Positron emission tomography images were processed with SPM2.The brain areas activated after needling at ST36 included the left hippocampus,the left orbital cortex,the left infralimbic cortex,the left olfactory cortex,the left cerebellum and the left pons.In the sham-point group,the activated regions were similar to those in the ST36 group.However,the ST36 group showed greater activation in the cerebellum and pons than the sham-point group.These findings suggest that long-term acupuncture treatment has targeted regulatory effects on multiple brain regions in rats with Alzheimer＇s disease.展开更多
First, the paper analyzes the advantages and disadvantages of all kinds of reactive power compensation technology, and then proposes a principle and integrated control strategy of the composite operation of TSC and SV...First, the paper analyzes the advantages and disadvantages of all kinds of reactive power compensation technology, and then proposes a principle and integrated control strategy of the composite operation of TSC and SVG, also the paper designs and develops the main controller of Network based composite power quality regulation device, based on RTDS, the real-time digital simulation model of The Device is established, and finally the prototype of the device is developed with the function of filter and split-phase compensation. The main controller determines the cooperative operation of both TSC and SVG, and the switching strategy of TSC. The simulation result in RTDS can verify the precision of the measure system and the validity of the control logic, the prototype has finished the type test according to the national standard.展开更多
为提高低压差线性稳压器(Low-DropOut Linear Regulator,LDO)的稳定性并降低前馈电路所产生的噪声,提出了一种生成自适应补偿零点的低噪声前馈电路。该前馈电路通过镜像调整管的负载电流,通过低值反馈电阻形成高增益反馈信号,与LDO输出...为提高低压差线性稳压器(Low-DropOut Linear Regulator,LDO)的稳定性并降低前馈电路所产生的噪声,提出了一种生成自适应补偿零点的低噪声前馈电路。该前馈电路通过镜像调整管的负载电流,通过低值反馈电阻形成高增益反馈信号,与LDO输出电压经反馈网络传递给反馈端的信号耦合形成由负载电容、负载电流控制的可控零点,可有效提高LDO电路整体的稳定性。此外,电路内部加入了产生动态极点的自适应电流补偿电路以保证次极点不会对环路的相位裕度产生影响。基于0.18μm BCD工艺设计,该电路在0~800 mA的宽负载范围、5 V输入3.3 V输出下相位裕度均高于48°,适用负载电容范围≥1μF,同时该LDO在10~100 kHz的频率范围内输出噪声仅为5.0617μVrms。展开更多
随着大规模新能源接入电网,新型电力系统“低惯量、弱支撑”特征凸显,电网频率调节资源日益稀缺,系统频率稳定问题愈发严峻。先进绝热压缩空气储能(advanced adiabatic compressed air energy storage,AA-CAES)具有容量大、寿命长等优...随着大规模新能源接入电网,新型电力系统“低惯量、弱支撑”特征凸显,电网频率调节资源日益稀缺,系统频率稳定问题愈发严峻。先进绝热压缩空气储能(advanced adiabatic compressed air energy storage,AA-CAES)具有容量大、寿命长等优势而受到广泛关注,但由于其储能和释能过程涉及气-热动态耦合过程,调频特性较为复杂,调频潜力还有待挖掘。因此,首先建立AA-CAES系统全工况动态仿真模型,进而基于期望频率动态曲线设计AA-CAES系统调频传递函数,优化目标传递函数关键参数,实现AA-CAES最小动态功率补偿下满足系统频率调节需求。最后通过仿真实验,验证了所提控制策略可优化AA-CAES调频容量的同时减小系统的稳态频率偏差与频率超调量,显著改善频率响应特性,为建设电网友好型AA-CAES电站提供技术支撑。展开更多
A CMOS （complementary metal-oxide-semiconductor transistor） low-dropout regulator （LDO） with 3. 3 V output voltage and 100 mA output current for system-on-chip applications to reduce board space and external pins ...A CMOS （complementary metal-oxide-semiconductor transistor） low-dropout regulator （LDO） with 3. 3 V output voltage and 100 mA output current for system-on-chip applications to reduce board space and external pins is presented. By utilizing a dynamic slew-rate enhancement（SRE） circuit and nested Miller compensation （NMC） on the LDO structure, the proposed LDO provides high stability during line and load regulation without off-chip load capacitors. The overshot voltage is limited within 550 mV and the settling time is less than 50 μs when the load current decreases from 100 mA to 1 mA. By using a 30 nA reference current, the quiescent current is 3.3 μA. The proposed design is implemented by CSMC 0. 5 μm mixed-signal process. The experimental results agree with the simulation results.展开更多
基金supported by the National Basic Research Program of China(973 Program),No.2006CB504505,2012CB518504the National Natural Science Foundation of China,No.90709027+1 种基金the Student's Platform for Innovation and Entrepreneurship Training Program of Southern Medical University of China,No.201512121165the Doctoral Foundation of Guangdong Medical University of China,No.2XB13058
文摘The acute effect of acupuncture on Alzheimer＇s disease,i.e.,on brain activation during treatment,has been reported.However,the effect of long-term acupuncture on brain activation in Alzheimer＇s disease is unclear.Therefore,in this study,we performed long-term needling at Zusanli（ST36）or a sham point（1.5 mm lateral to ST36）in a rat Alzheimer＇s disease model,for 30 minutes,once per day,for 30 days.The rats underwent 18F-fluorodeoxyglucose positron emission tomography scanning.Positron emission tomography images were processed with SPM2.The brain areas activated after needling at ST36 included the left hippocampus,the left orbital cortex,the left infralimbic cortex,the left olfactory cortex,the left cerebellum and the left pons.In the sham-point group,the activated regions were similar to those in the ST36 group.However,the ST36 group showed greater activation in the cerebellum and pons than the sham-point group.These findings suggest that long-term acupuncture treatment has targeted regulatory effects on multiple brain regions in rats with Alzheimer＇s disease.
文摘First, the paper analyzes the advantages and disadvantages of all kinds of reactive power compensation technology, and then proposes a principle and integrated control strategy of the composite operation of TSC and SVG, also the paper designs and develops the main controller of Network based composite power quality regulation device, based on RTDS, the real-time digital simulation model of The Device is established, and finally the prototype of the device is developed with the function of filter and split-phase compensation. The main controller determines the cooperative operation of both TSC and SVG, and the switching strategy of TSC. The simulation result in RTDS can verify the precision of the measure system and the validity of the control logic, the prototype has finished the type test according to the national standard.
文摘随着大规模新能源接入电网,新型电力系统“低惯量、弱支撑”特征凸显,电网频率调节资源日益稀缺,系统频率稳定问题愈发严峻。先进绝热压缩空气储能(advanced adiabatic compressed air energy storage,AA-CAES)具有容量大、寿命长等优势而受到广泛关注,但由于其储能和释能过程涉及气-热动态耦合过程,调频特性较为复杂,调频潜力还有待挖掘。因此,首先建立AA-CAES系统全工况动态仿真模型,进而基于期望频率动态曲线设计AA-CAES系统调频传递函数,优化目标传递函数关键参数,实现AA-CAES最小动态功率补偿下满足系统频率调节需求。最后通过仿真实验,验证了所提控制策略可优化AA-CAES调频容量的同时减小系统的稳态频率偏差与频率超调量,显著改善频率响应特性,为建设电网友好型AA-CAES电站提供技术支撑。
基金The Key Science and Technology Project of Zhejiang Province(No.2007C21021)
文摘A CMOS （complementary metal-oxide-semiconductor transistor） low-dropout regulator （LDO） with 3. 3 V output voltage and 100 mA output current for system-on-chip applications to reduce board space and external pins is presented. By utilizing a dynamic slew-rate enhancement（SRE） circuit and nested Miller compensation （NMC） on the LDO structure, the proposed LDO provides high stability during line and load regulation without off-chip load capacitors. The overshot voltage is limited within 550 mV and the settling time is less than 50 μs when the load current decreases from 100 mA to 1 mA. By using a 30 nA reference current, the quiescent current is 3.3 μA. The proposed design is implemented by CSMC 0. 5 μm mixed-signal process. The experimental results agree with the simulation results.
