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Use of Pearson’s Chi-Square for Testing Equality of Percentile Profiles across Multiple Populations
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作者 William D. Johnson Robbie A. Beyl +3 位作者 Jeffrey H. Burton Callie M. Johnson Jacob E. Romer Lei Zhang 《Open Journal of Statistics》 2015年第5期412-420,共9页
In large sample studies where distributions may be skewed and not readily transformed to symmetry, it may be of greater interest to compare different distributions in terms of percentiles rather than means. For exampl... In large sample studies where distributions may be skewed and not readily transformed to symmetry, it may be of greater interest to compare different distributions in terms of percentiles rather than means. For example, it may be more informative to compare two or more populations with respect to their within population distributions by testing the hypothesis that their corresponding respective 10th, 50th, and 90th percentiles are equal. As a generalization of the median test, the proposed test statistic is asymptotically distributed as Chi-square with degrees of freedom dependent upon the number of percentiles tested and constraints of the null hypothesis. Results from simulation studies are used to validate the nominal 0.05 significance level under the null hypothesis, and asymptotic power properties that are suitable for testing equality of percentile profiles against selected profile discrepancies for a variety of underlying distributions. A pragmatic example is provided to illustrate the comparison of the percentile profiles for four body mass index distributions. 展开更多
关键词 Asymptotic chi-square test EQUALITY of PERCENTILES Large Sample test MEDIAN test NONPARAMETRIC Methods
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大锻件统计学Chi-square test的研究和应用 被引量:3
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作者 齐作玉 吕亚臣 任运来 《大型铸锻件》 2011年第1期9-11,25,共4页
根据大锻件生产的特点和统计学的基本理论方法,首次深入浅出地论述了大锻件的Chi-square test,即X2检验,并给出了具体应用示例。该方法可用于大锻件工艺参数的科学分析和生产验证,可用于大锻件质量分析和判断,可帮助逐步建立起大锻件的... 根据大锻件生产的特点和统计学的基本理论方法,首次深入浅出地论述了大锻件的Chi-square test,即X2检验,并给出了具体应用示例。该方法可用于大锻件工艺参数的科学分析和生产验证,可用于大锻件质量分析和判断,可帮助逐步建立起大锻件的工序能力,帮助实现稳定并提升大锻件工艺和质量控制水平。 展开更多
关键词 大锻件 chi-square test 统计学
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Optimization Method of Suspected Electricity Theft Topic Model Based on Chi-square Test and Logistic Regression 被引量:1
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作者 Jian Dou Ye Aliaosha 《国际计算机前沿大会会议论文集》 2018年第2期32-32,共1页
关键词 Anti-electricity THEFT chi-square test LOGISTIC regressionPower consumption inspection
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Large Deviations and Moderate Deviations for the Chi-Square Test in Type Ⅱ Error
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作者 JIANG Hui GAO Fuqing 《Wuhan University Journal of Natural Sciences》 CAS 2008年第2期129-132,共4页
We study the asymptotics tot the statistic of chi-square in type Ⅱ error. By the contraction principle, the large deviations and moderate deviations are obtained, and the rate function of moderate deviations can be c... We study the asymptotics tot the statistic of chi-square in type Ⅱ error. By the contraction principle, the large deviations and moderate deviations are obtained, and the rate function of moderate deviations can be calculated explicitly which is a squared function. 展开更多
关键词 large deviations moderate deviations chi-square test
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A Simple Chi-Square Statistic for Testing Homogeneity of Zero-Inflated Distributions
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作者 William D. Johnson Jeffrey H. Burton +1 位作者 Robbie A. Beyl Jacob E. Romer 《Open Journal of Statistics》 2015年第6期483-493,共11页
Zero-inflated distributions are common in statistical problems where there is interest in testing homogeneity of two or more independent groups. Often, the underlying distribution that has an inflated number of zero-v... Zero-inflated distributions are common in statistical problems where there is interest in testing homogeneity of two or more independent groups. Often, the underlying distribution that has an inflated number of zero-valued observations is asymmetric, and its functional form may not be known or easily characterized. In this case, comparisons of the groups in terms of their respective percentiles may be appropriate as these estimates are nonparametric and more robust to outliers and other irregularities. The median test is often used to compare distributions with similar but asymmetric shapes but may be uninformative when there are excess zeros or dissimilar shapes. For zero-inflated distributions, it is useful to compare the distributions with respect to their proportion of zeros, coupled with the comparison of percentile profiles for the observed non-zero values. A simple chi-square test for simultaneous testing of these two components is proposed, applicable to both continuous and discrete data. Results of simulation studies are reported to summarize empirical power under several scenarios. We give recommendations for the minimum sample size which is necessary to achieve suitable test performance in specific examples. 展开更多
关键词 Asymptotic chi-square test EQUALITY of QUANTILES Large Sample test Nonparametric test Percentile Profiles ZERO-INFLATED DISTRIBUTIONS
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Chi-Square Distribution: New Derivations and Environmental Application
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作者 Thomas M. Semkow Nicole Freeman +8 位作者 Umme-Farzana Syed Douglas K. Haines Abdul Bari Abdul J. Khan Kimi Nishikawa Adil Khan Adam G. Burn Xin Li Liang T. Chu 《Journal of Applied Mathematics and Physics》 2019年第8期1786-1799,共14页
We describe two new derivations of the chi-square distribution. The first derivation uses the induction method, which requires only a single integral to calculate. The second derivation uses the Laplace transform and ... We describe two new derivations of the chi-square distribution. The first derivation uses the induction method, which requires only a single integral to calculate. The second derivation uses the Laplace transform and requires minimum assumptions. The new derivations are compared with the established derivations, such as by convolution, moment generating function, and Bayesian inference. The chi-square testing has seen many applications to physics and other fields. We describe a unique version of the chi-square test where both the variance and location are tested, which is then applied to environmental data. The chi-square test is used to make a judgment whether a laboratory method is capable of detection of gross alpha and beta radioactivity in drinking water for regulatory monitoring to protect health of population. A case of a failure of the chi-square test and its amelioration are described. The chi-square test is compared to and supplemented by the t-test. 展开更多
关键词 Mathematical Induction LAPLACE Transform GAMMA Distribution chi-square test GROSS Alpha-Beta DRINKING Water
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基于Pearson相关性检验的ARIMA边坡位移监测模型 被引量:16
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作者 胡添翼 杨光 +2 位作者 陈波 俞扬 陶园 《水利水电技术》 CSCD 北大核心 2016年第1期71-75,共5页
在运用传统ARIMA预测模型的基础上,引入Pearson相关性检验,定量分析了空间上不同测点位移之间的相关性,判断了被监测区域在空间上是否有整体位移或者局部位移的趋势,以便能对被监测区域空间整体的位移性态进行更全面地掌握。实例分析表... 在运用传统ARIMA预测模型的基础上,引入Pearson相关性检验,定量分析了空间上不同测点位移之间的相关性,判断了被监测区域在空间上是否有整体位移或者局部位移的趋势,以便能对被监测区域空间整体的位移性态进行更全面地掌握。实例分析表明,该模型的预测能力较好,能较准确地预测边坡位移,并能有效辨别边坡整体位移情况及稳定状态。 展开更多
关键词 pearson相关检验 位移 ARIMA模型 预测
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关于Neyman-Pearson基本引理的几个注记 被引量:7
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作者 王金亮 余海燕 +1 位作者 胡松波 刘文君 《数学杂志》 CSCD 北大核心 2011年第2期357-361,共5页
本文探讨了Neyman-Pearson基本引理.通过论证总体参数θ只有θ_0或θ_1两种可能时最优检验功效函数的唯一性,得到了两种假设T_1:θ=θ_0←→θ=θ_1和T_2:θ=θ_1←→θ=θ_0各自对应最优检验的两类错误概率可以互换的结论.
关键词 Neyman-pearson基本引理 最优检验 随机化检验 功效函数
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Association between people’s attitudes towards human-elephant conflict and their locational,demographic,and socio-economic characteristics in Buxa Tiger Reserve and its adjoining area,India
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作者 Chiranjib NAD Tamal BASU-ROY 《Regional Sustainability》 2024年第1期11-25,共15页
“Human-elephant conflict(HEC)”,the alarming issue,in present day context has attracted the attention of environmentalists and policy makers.The rising conflict between human beings and wild elephants is common in Bu... “Human-elephant conflict(HEC)”,the alarming issue,in present day context has attracted the attention of environmentalists and policy makers.The rising conflict between human beings and wild elephants is common in Buxa Tiger Reserve(BTR)and its adjoining area in West Bengal State,India,making the area volatile.People’s attitudes towards elephant conservation activity are very crucial to get rid of HEC,because people’s proximity with wild elephants’habitat can trigger the occurrence of HEC.The aim of this study is to conduct an in-depth investigation about the association of people’s attitudes towards HEC with their locational,demographic,and socio-economic characteristics in BTR and its adjoining area by using Pearson’s bivariate chi-square test and binary logistic regression analysis.BTR is one of the constituent parts of Eastern Doors Elephant Reserve(EDER).We interviewed 500 respondents to understand their perceptions to HEC and investigated their locational,demographic,and socio-economic characteristics including location of village,gender,age,ethnicity,religion,caste,poverty level,education level,primary occupation,secondary occupation,household type,and source of firewood.The results indicate that respondents who are living in enclave forest villages(EFVs),peripheral forest villages(PFVs),corridor village(CVs),or forest and corridor villages(FCVs),mainly males,at the age of 18–48 years old,engaged with agriculture occupation,and living in kancha and mixed houses,have more likelihood to witness HEC.Besides,respondents who are illiterate or at primary education level are more likely to regard elephant as a main problematic animal around their villages and refuse to participate in elephant conservation activity.For the sake of a sustainable environment for both human beings and wildlife,people’s attitudes towards elephants must be friendly in a more prudent way,so that the two communities can live in harmony. 展开更多
关键词 Human-elephant conflict Elephant conservation chi-square test statistics Binary logistic regression Demographic and socioeconomic characteristics Buxa Tiger Reserve
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Spatio-temporal Variation Characteristics of Extreme Climate Events and Their Teleconnections to Large-scale Ocean-atmospheric Circulation Patterns in Huaihe River Basin,China During 1959–2019
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作者 YAO Tian ZHAO Qiang +6 位作者 WU Chuanhao HU Xiaonong XIA Chuan'an WANG Xuan SANG Guoqiang LIU Jian WANG Haijun 《Chinese Geographical Science》 SCIE CSCD 2024年第1期118-134,共17页
Huaihe River Basin(HRB) is located in China’s north-south climatic transition zone,which is very sensitive to global climate change.Based on the daily maximum temperature,minimum temperature,and precipitation data of... Huaihe River Basin(HRB) is located in China’s north-south climatic transition zone,which is very sensitive to global climate change.Based on the daily maximum temperature,minimum temperature,and precipitation data of 40 meteorological stations and nine monthly large-scale ocean-atmospheric circulation indices data during 1959–2019,we present an assessment of the spatial and temporal variations of extreme temperature and precipitation events in the HRB using nine extreme climate indices,and analyze the teleconnection relationship between extreme climate indices and large-scale ocean-atmospheric circulation indices.The results show that warm extreme indices show a significant(P < 0.05) increasing trend,while cold extreme indices(except for cold spell duration) and diurnal temperature range(DTR) show a significant decreasing trend.Furthermore,all extreme temperature indices show significant mutations during 1959-2019.Spatially,a stronger warming trend occurs in eastern HRB than western HRB,while maximum 5-d precipitation(Rx5day) and rainstorm days(R25) show an increasing trend in the southern,central,and northwestern regions of HRB.Arctic oscillation(AO),Atlantic multidecadal oscillation(AMO),and East Atlantic/Western Russia(EA/WR) have a stronger correlation with extreme climate indices compared to other circulation indices.AO and AMO(EA/WR) exhibit a significant(P < 0.05) negative(positive)correlation with frost days and diurnal temperature range.Extreme warm events are strongly correlated with the variability of AMO and EA/WR in most parts of HRB,while extreme cold events are closely related to the variability of AO and AMO in eastern HRB.In contrast,AMO,AO,and EA/WR show limited impacts on extreme precipitation events in most parts of HRB. 展开更多
关键词 extreme climate indices Sen’s slope variation mutation test atmospheric circulation indices pearson’s correlation analysis Huaihe River Basin(HRB) China
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P值大小不等价于差异或相关性大小
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作者 郑巧兰 林燕薇 王景周 《数理医药学杂志》 CAS 2024年第3期158-163,共6页
目的探讨P值与差异或相关性大小的关系。方法固定样本统计量[均数和标准差、样本率、相关系数、OR(95%CI)],分别模拟独立样本t检验、两组样本率比较的卡方检验、Pearson相关分析、单因素Logistic回归分析的数据,观察不同样本量下P值差... 目的探讨P值与差异或相关性大小的关系。方法固定样本统计量[均数和标准差、样本率、相关系数、OR(95%CI)],分别模拟独立样本t检验、两组样本率比较的卡方检验、Pearson相关分析、单因素Logistic回归分析的数据,观察不同样本量下P值差异。结果两组样本统计量相同或单组样本统计量一致但样本量不同时,P值可能大于0.05、介于0.001~0.05或小于0.001。结论P值受样本量影响大,其大小不等价于差异或相关性大小。 展开更多
关键词 P值 T检验 卡方检验 pearson相关分析 LOGISTIC回归分析
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红外光谱结合统计学方法对纸质包装盒的检验研究
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作者 汪子拓 姜红 +2 位作者 谢皓东 杨棋驭 徐沐暄 《包装工程》 CAS 北大核心 2024年第9期178-184,共7页
目的建立一种高效准确的红外光谱检验纸质包装盒的研究方法。方法利用傅里叶变换红外光谱仪测得了56个不同类型不同来源的纸质包装盒的红外光谱数据;根据纸盒主要填料的不同,将样品初步分为三大类;利用主成分分析对初步分类后的数据降维... 目的建立一种高效准确的红外光谱检验纸质包装盒的研究方法。方法利用傅里叶变换红外光谱仪测得了56个不同类型不同来源的纸质包装盒的红外光谱数据;根据纸盒主要填料的不同,将样品初步分为三大类;利用主成分分析对初步分类后的数据降维,提取出4个主成分,再利用系统聚类将样品最终分为6组,使用K-means聚类算法结合Pearson卡方检验进行验证,与最终分类的结果基本吻合。基于该分组,训练朴素贝叶斯分类、随机森林模型、XGBoost分类3种判别模型,实现对新样品组别的分类预测。结果56个快递包装纸盒样品被分为3类,而后进一步细分为6组,3种判别预测模型均有较高的准确率,其中随机森林模型的准确率最高。结论该方法快速方便地实现了对样品的区分,并且可以实现无损检验,为犯罪现场纸质包装盒的鉴别提供依据,从而为公安侦查工作的开展提供帮助。 展开更多
关键词 纸质包装盒 傅里叶变换红外光谱法 pearson卡方检验 朴素贝叶斯分类 随机森林模型 XGBoost分类
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菜子湖水位变化对水质的影响
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作者 利俊峰 杨鑫 《安徽化工》 CAS 2024年第2期124-129,共6页
针对菜子湖水质对水位变化的响应问题,基于菜子湖国控断面水质和车富岭水文站水位监测数据,运用夏皮罗-威尔克检验、斯皮尔曼和皮尔逊相关系数法分析菜子湖水位与水质(TN、TP、COD、高锰酸盐指数等主要因子)之间的关系。结果表明:菜子... 针对菜子湖水质对水位变化的响应问题,基于菜子湖国控断面水质和车富岭水文站水位监测数据,运用夏皮罗-威尔克检验、斯皮尔曼和皮尔逊相关系数法分析菜子湖水位与水质(TN、TP、COD、高锰酸盐指数等主要因子)之间的关系。结果表明:菜子湖年内水位呈现单峰变化,波动幅度较大,洪-枯季节性交替,水文节律明显,丰、枯水期平均水位落差3.79 m。菜子湖水位与TP浓度呈显著负相关(R=-0.604)。菜子湖水位在12 m左右时,湖区水质浓度维持在较低水平。菜子湖水位(尤其是枯水期)变化影响水质稳定达标及改善。此外,引江济淮工程调水导致菜子湖水文要素变化对水质的影响需进一步予以关注。 展开更多
关键词 环境科学 水质水位 斯皮尔曼和皮尔逊相关系数 菜子湖 夏皮罗-威尔克检验
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山东省高速公路与区域经济融合协调评价与发展策略研究
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作者 刘志鹏 李冬麒 +2 位作者 施庆利 王新 韩国华 《山东交通科技》 2024年第3期21-25,34,共6页
在揭示高速公路与区域经济融合协调发展必要性的基础上,以山东省16个地级市高速公路与区域经济相关数据为基础,采用耦合协调度模型和皮尔逊检验对山东省高速公路与区域经济融合发展的区域差异特征和相互作用的时间变化特征进行了评价,... 在揭示高速公路与区域经济融合协调发展必要性的基础上,以山东省16个地级市高速公路与区域经济相关数据为基础,采用耦合协调度模型和皮尔逊检验对山东省高速公路与区域经济融合发展的区域差异特征和相互作用的时间变化特征进行了评价,进而从不同角度对推动高速公路与区域经济融合协调发展、强化高速公路对区域经济发展的促进作用提出了具有现实可行性的策略建议。研究结果表明,山东省区域经济和高速公路发展处于强耦合、强作用阶段,而高速公路里程对国内生产总值增长的作用程度及其显著性整体呈现一定弱化趋势,山东省仍需提高高速公路与区域经济融合协调,强化高速公路对区域经济的促进作用。 展开更多
关键词 高速公路 区域经济发展 耦合协调度模型 皮尔逊检验
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Practical integrated navigation fault detection algorithm based on sequential hypothesis testing 被引量:8
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作者 Feng Yang Cheng Cheng Quan Pan Gongyuan Zhang 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2011年第1期146-149,共4页
In detecting system fault algorithms,the false alarm rate and undectect rate generated by residual Chi-square test can affect the stability of filters.The paper proposes a fault detection algorithm based on sequential... In detecting system fault algorithms,the false alarm rate and undectect rate generated by residual Chi-square test can affect the stability of filters.The paper proposes a fault detection algorithm based on sequential residual Chi-square test and applies to fault detection of an integrated navigation system.The simulation result shows that the algorithm can accurately detect the fault information of global positioning system(GPS),eliminate the influence of false alarm and missed detection on filter,and enhance fault tolerance of integrated navigation systems. 展开更多
关键词 residual chi-square test integrated navigation fault detection.
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Consistency check of degradation mechanism between natural storage and enhancement test for missile servo system 被引量:3
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作者 Wang Xu Sun Quan 《Journal of Systems Engineering and Electronics》 SCIE EI CSCD 2019年第2期415-424,共10页
Reliability enhancement testing(RET) is an accelerated testing which hastens the performance degradation process to surface its inherent defects of design and manufacture. It is an important hypothesis that the degrad... Reliability enhancement testing(RET) is an accelerated testing which hastens the performance degradation process to surface its inherent defects of design and manufacture. It is an important hypothesis that the degradation mechanism of the RET is the same as the one of the normal stress condition. In order to check the consistency of two mechanisms, we conduct two enhancement tests with a missile servo system as an object of the study, and preprocess two sets of test data to establish the accelerated degradation models regarding the temperature change rate that is assumed to be the main applied stress of the servo system during the natural storage. Based on the accelerated degradation models and natural storage profile of the servo system, we provide and demonstrate a procedure to check the consistency of two mechanisms by checking the correlation and difference of two sets of degradation data. The results indicate that the two degradation mechanisms are significantly consistent with each other. 展开更多
关键词 reliability ENHANCEMENT testing (RET) degradation model ACCELERATED equation CONSISTENCY CHECK pearson correlation coefficient
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A Note on Cochran Test for Homogeneity in Two Ways ANOVA and Meta-Analysis
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作者 Pamphile Mezui-Mbeng 《Open Journal of Statistics》 2015年第7期787-796,共10页
In this paper, we generalize the proof of the Cochran statistic in the case of an ANOVA two ways structure that asymptotically follows a Chi-2. While construction of homogeneity statistics test usually resorts to the ... In this paper, we generalize the proof of the Cochran statistic in the case of an ANOVA two ways structure that asymptotically follows a Chi-2. While construction of homogeneity statistics test usually resorts to the determination of the covariance matrix and its inverse, the Moore-Penrose matrix, our approach, avoids this step. We also show that the Cochran statistic in ANOVA two ways is equivalent to conventional homogeneity statistics test. In particular, we show that it satisfies the invariance property. Finally, we conduct empirical verification from a meta-analysis that confirms our theoretical results. 展开更多
关键词 Cochran HOMOGENEITY test chi-square Distribution Desimonian-Laird test INVARIANT Two WAYS ANOVA
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Pearson x^2检验在计算机自适应化测验中的应用研究
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作者 熊春明 《计算机与现代化》 2008年第1期24-25,28,共3页
计算机化自应用测验(CAT)使用项目反应理论(IRT),通过观察被试在项目上的反应,将能力和项目参数的关系用数学模型表达出来。如何有效地估计被试的能力,是计算机化自适应测验的一个关键问题。本文首先论述了Berkson的最小化x2方法,但使... 计算机化自应用测验(CAT)使用项目反应理论(IRT),通过观察被试在项目上的反应,将能力和项目参数的关系用数学模型表达出来。如何有效地估计被试的能力,是计算机化自适应测验的一个关键问题。本文首先论述了Berkson的最小化x2方法,但使用该方法的前提是已知被试的能力,且运用了Pearson x2检验的思想。接着指出该方法中存在的缺陷,进而提出了一种新的解决方案,该新方案可弥补Berkson的最小化x2方法的不足之处,可以作为该方法的一个改进。本文的研究表明,新的方案比Berkson的最小化x2方法具有更加科学的解释能力。 展开更多
关键词 计算机化自适应测验 最小化x^2方法 pearson X^2检验 项目反应理论 项目反应模型 先验分布 后验分布 人工数据
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HIV Testing Decision and Determining Factors in Ghana
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作者 Abdul-Karim Iddrisu Kwaku Opoku-Ameyaw +2 位作者 Francis Kwame Bukari Bashiru Mahama Jerry John Amaasende Akooti 《World Journal of AIDS》 2019年第2期85-104,共20页
Knowledge on individual’s HIV/AIDS status provides a tool to reduce or avoid HIV transmission, spread and mortalities due to HIV-related illness. However, most people still do not know their HIV status because they a... Knowledge on individual’s HIV/AIDS status provides a tool to reduce or avoid HIV transmission, spread and mortalities due to HIV-related illness. However, most people still do not know their HIV status because they are not willing to test for HIV/AIDS due to various reasons. Hence the aim of this paper is to investigate the effects of various risk factors that are likely to influence decision to ever test for HIV/AIDS. The data used in this paper were obtained from the Ghana Demographic and Health Survey (n = 1828 observations and 32 risk factors). We applied the Chi-Square test statistic and the logistic regression model to the data in order to study the effects of these risk factors on one’s decision to ever test for HIV. STATA version 14.1 and R version 3.5.2 were used to carry out the statistical analyses. Generally, the results show that education, especially higher education significantly (OR = 0.53, 95% = 0.230, 0.837) increases the likelihood to ever test for HIV. Also, the younger the age groups the higher the effect and significance in the likelihood to ever test for HIV. We found that HIV-TB co-infection (OR = 0.53, 95% = 0.165, 0.893), use of condom anytime one has sex (OR = 0.31, 95% = 0.054, 0.573), wealth index (OR = 0.46, 95% = 0.137, 0.791), awareness of HIV transmission during child-delivery, number of partners significantly affect HIV testing. Those with many partners are less likely (OR = -0.26, 95% = -0.504, -0.007) to ever test for HIV and those who know that healthy person may have HIV are more likely (OR = 0.41, 95% = 0.137, 0.679) to ever test for HIV. Age is the common significant risk factor of ever tested for HIV across the 10 regions in Ghana. Resources should be allocated for more education on these significant risk factors in order to help in the fight against HIV-Health related issues. 展开更多
关键词 AIDS chi-square test Statistic Ghana DEMOGRAPHIC and Health Survey HIV HIV-TB CO-INFECTION LOGISTIC Regression Model Risk Factors
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On the Different Ways to Handle the Trend of Disease Risk in Genetic Association Tests
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作者 Tapati Basak 《Open Journal of Statistics》 2022年第4期521-531,共11页
Genetic association studies usually apply the simple chi-square (χ<sup>2</sup>)-test for testing association between a single-nucleotide polymorphism (SNP) and a particular phenotype, assuming the genotyp... Genetic association studies usually apply the simple chi-square (χ<sup>2</sup>)-test for testing association between a single-nucleotide polymorphism (SNP) and a particular phenotype, assuming the genotypes and phenotypes are independent. So, the conventional χ<sup>2</sup>-test does not consider the increased risk of an individual carrying the increasing number of disease responsible allele (a particular genotype). But, the association tests should be performed with the consideration of this disease risk according to the mode of inheritance (additive, dominant, recessive). Practical demonstration of the two possible methods for considering such order or trends in contingency tables of genetic association studies using SNP genotype data is the purpose of this paper. One method is by pooling the genotypes, and the other is scoring the individual genotypes, based on the disease risk according to the inheritance pattern. The results show that the p-values obtained from both the methods are similar for the dominant and recessive models. The other important features of the methods were also extracted using the SNP genotype data for different inheritance patterns. 展开更多
关键词 Association chi-square Trend test SNP GENOTYPE
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