Curative effect of hydrogen peroxide combined with silver ion disinfection on pelvic floor dysfunction

BACKGROUND Pelvic floor dysfunction(PFD)is related to muscle fiber tearing during childbirth,negatively impacting postpartum quality of life of parturient.Appropriate and effective intervention is necessary to promote PFD recovery.AIM To analyze the use of hydrogen peroxide and silver ion disinfection for vaginal electrodes in conjunction with comprehensive rehabilitation therapy for postpartum women with PFD.METHODS A total of 59 women with PFD who were admitted to the hospital from May 2019 to July 2022 were divided into two groups:Control group(n=27)received comprehensive rehabilitation therapy and observation group(n=32)received intervention with pelvic floor biostimulation feedback instrument in addition to comprehensive rehabilitation therapy.The vaginal electrodes were disinfected with hydrogen peroxide and silver ion before treatment.Intervention for both groups was started 6 weeks postpartum,and rehabilitation lasted for 3 months.Pelvic floor muscle voltage,pelvic floor muscle strength,vaginal muscle voltage,vaginal muscle tone,pelvic floor function,quality of life,and incidence of postpartum PFD were compared between the two groups.RESULTS Before comprehensive rehabilitation treatment,basic data and pelvic floor function were not significantly different between the two groups.After treatment,the observation group showed significant improvements in the maximum voltage and average voltage of pelvic floor muscles,contraction time of type I and type II fibers,pelvic floor muscle strength,vaginal muscle tone,vaginal muscle voltage,and quality of life(GQOLI-74 reports),compared with the control group.The observation group had lower scores on the pelvic floor distress inventory(PFDI-20)and a lower incidence of postpartum PFD,indicating the effectiveness of the pelvic floor biostimulation feedback instrument in promoting the recovery of maternal pelvic floor function.CONCLUSION The combination of the pelvic floor biostimulation feedback instrument and comprehensive rehabilitation nursing can improve pelvic floor muscle strength,promote the recovery of vaginal muscle tone,and improve pelvic floor function and quality of life.The use of hydrogen peroxide and silver ion disinfectant demonstrated favorable antibacterial efficacy and is worthy of clinical application.

Expression and significance of lysyl oxidase-like 1 and fibulin-5 in the cardinal ligament tissue of patients with pelvic floor dysfunction

Pelvic organ prolapse （POP） is a disabling disorder in women characterized by a loss of pelvic floor support, leading to the herniation of the uterus into or through the vagina. POP is a complex problem that likely involves multiple mechanisms with limited therapies available, and is associated with defects in connective tissue including elastic fibers. This study was designed to investigate the expression of fibulin-5 and lysyl oxidase-like 1 （LOXL1） in the cardinal ligament in samples taken from the POP group compared to the non-POP group. Specimens were obtained during abdominal hysterectomy from the cardinal ligament of 53 women with POP and 25 age- and par- ity- matched women with non-POP among post-menopausal women with benign gynecologic pathology. Protein expression was evaluated using the immunohistochemical staining method. For statistical analyses, chi-square test and Spearman＇s correlation were used with the statistical package SPSS13.0 system. Our results showed that both fibulin-5 and LOXL1 expressions were decreased in the cardinal ligament in the POP group compared to the non- POP group （P 〈 0.05）. The expression of fibulin-5 and LOXL1 were correlated closely with the stage of POP, ac- companied by stress urinary incontinence and frequency of vaginal delivery （P 〈 0.05）, but had no relationship with post-menopausal state （P 〉 0.05）. The expression of fibulin-5 was positively associated with LOXL1 in POP （P 〈 0.05）. We conclude that changes in fibulin-5 and LOXL1 expression may play a role in the development of POP.

Technical Innovation of Electrostimulation Biofeedback Combined with Vaginal Dumbbell in the Treatment of Postpartum Pelvic Floor Dysfunction

Objective: To investigate the application value of electrostimulation biofeedback therapy in combination with vaginal dumbbell therapy to postpartum pelvic floor dysfunction. Methods: Retrospective analysis of 200 cases of postpartum pelvic floor dysfunction patients discharged from the hospital from January 2016 to March 2019 as study subjects who were excluded other underlying diseases and were randomly divided into two groups of 100 cases per group, using electrostimulation biofeedback therapy combined vaginal dumbbell therapy as a treatment group. The treatment of electrostimulation biofeedback therapy in combination with kegel was treated as a control group. Then the curative effects of the two groups were compared and statistically analyzed. Results: There was no significant difference in EMG value of postpartum pelvic floor treatment, type I muscle strength, type II muscle strength, muscle type I fatigue, type II fatigue and POP-Q detection results between the two groups before treatment, p > 0.05. There were significant differences in type I muscle strength, type II muscle strength and muscle type I fatigue between the pelvic floor muscles and the muscles at the end of the treatment day, the sixth month and one year after treatment, p ?There was no statistically significant difference at?the end of muscle type II fatigue?treatment day, p > 0.05;while after the treatment of six months and one year, the difference was statistically significant, p 0.05. In addition, the treatment group and the control group were compared before and after treatment, the difference of myoelectric potential value, pelvic floor muscle type I muscle strength, type II muscle strength, muscle type I fatigue degree, type II fatigue degree and POP-Q test result were significant, and the changes in the indicators before and after treatment in the treatment group were significantly higher than the control group. Comparison of urinary incontinence between the two groups before and after treatment, the difference between pre-treatment and the end of treatment day was not statistically significant, p > 0.05;there was significant difference between half a year and one year after treatment (p 0.05, respectively). Comparing?the satisfaction with sexual life after the time of treatment day, half a year and one year after the end of treatment, the difference was statistically significant (p ?Conclusion: Electrical stimulation biofeedback therapy combined with vaginal dumbbell therapy has a good effect in the treatment of postpartum pelvic floor dysfunction, and it is worthy of popularization and application.

Uterus-reserved or hysterectomized total pelvic floor reconstruction for female pelvic dysfunction:a clinical analysis of 74 cases

Objective To evaluate the effectiveness and safety of the entire pelvic floor reconstruction(Prolift) with uterus reserved in the treatment of pelvic floor dysfunction diseases.Methods From March 2008 to January 2009,74 female cases from our hospital who had different defects in pelvic organ prolapse were treated with the entire reconstructive pelvic surgery,in which 38 had uterus retained(observation group) and 36 cases had hysterectomy(control group).The two groups were compared.The patients with combined stress urinary incontinence had transobturator tension-free vaginal tape(TVT-O technique) at the same time.The results of operations were objectively evaluatedaccording to Pelvic Organ Prolapse Quantification sub-degree method(POP-Q) developed by the International Continence Society.Results For observation group,the average operative time was 50 min,and the average amount of bleeding was 100 mL.For control group,the average operative time was 110 min,and the average amount of bleeding was 200 mL.During the postoperative follow-up(8 ~18 months),in the observation group the structures of patients' pelvic floor were normal;stress urinary incontinence was all cured;related symptoms disappeared or were markedly improved;and no postoperative infection appeared.In control group,two cases had postoperative infection;the patients ' pelvic structures were normal during the postoperative follow-up;the related symptoms disappeared or were significantly improved.After 3 months,POP-Q score was significantly elevated in the two groups.Conclusion Full reconstructive pelvic surgery with uterus retained can complete the whole pelvic floor structure and function of all or part of the reconstruction with fast recovery and clear short-term effect.However,the long-term efficacy remains to be revealed.

Quantitatively evaluation on pelvic floor dysfunction by virtual touch tissue imaging quantification shear wave elastography

Objective:To investigate the value of(VTIQ)shear wave elastography in the diagnosis of pelvic floor dysfunction.Methods:20 patients with pelvic floor dysfunction and 40 healthy volunteers were enrolled in and devided into the pelvic floor dysfunction(PFD)group and the control group.20 cases in the normal non-fertile(NNF)group and the normal fertile(NF)group respectively were including in the control group.The Young's modulus of puborectalis(PR)in three groups was measured by virtual touch tissue imaging quantification(VTIQ)at different states.The Young's modulus of PR and their differences in the three groups and between groups were compared and calculated.Receiver-operating characteristic curve(ROC)analyses were performed to assess the diagnostic value of VTIQ,and the area under the curve(AUC)was compared.Results:Young's modulus of PR at resting-state,maximun rectal state and Vasalva state in NNF group and NF group were statistical significance(all P<0.05).Young's modulus of maximun rectal state was higher than that of resting-state and Vasalva state in PFD group(P<0.05).There was no significant difference in Young's modulus between the resting-state and Vasalva state in the PFD group(P>0.05).Difference of PR Young's modulus between resting status and maximun rectal state and that between resting status and Vasalva state were of statistical significance among the three groups(all P<0.05).ROC curves analyses indicated that the AUC,cut-off value,sensitivity,specificity and Youden index of the difference between the Young's modulus of resting status and maximun rectal state measured by VTIQ in control group and PFD group were 0.788,35.45kPa,91.67%,57.14%,0.488,espectively.The AUC,cut-off value,sensitivity,specificity and Youden index of the difference between the Young's modulus of resting status and Vasalva state measured by VTIQ in control group and PFD group were 0.799,14.00kPa,63.89%,85.71%,0.496,respectively.There was no significant difference in AUC between the two groups(Z=0.130,P>0.05).Conclusion:VTIQ technology is an effective method to quantitatively assess the biomechanical properties of PR.The effect of labor on the puborectalis muscle was not significant.The increase of Young's modulus of passive stretching in vasalva state was not significant in patients with pelvic floor dysfunction.The difference between resting status and maximun rectal state and difference between resting status and Vasalva state is more advantageous to the diagnosis of pelvic floor dysfunction disorder.

Effect of pelvic floor rehabilitation technique in preventing the postpartum pelvic floor dysfunction

Objective:To explore the effect of pelvic floor rehabilitation technique in preventing the postpartum pelvic floor dysfunction and on the sexual life quality.Methods:A total of 286 puerpera with pelvic floor dysfunction who were admitted in our hospital from May, 2014 to May, 201542 d after delivery were included in the study, and randomized into the treatment group and the control group with 143 cases in each group. After guidance, the puerpera in the control group were given pelvic floor muscle training by themselves at home. On this basis, the puerpera in the treatment group were treated by the pelvic floor rehabilitation apparatus. The puerpera in the two groups were treated for 4 weeks. The pelvic floor function before treatment, 6 months and 1 year after delivery was detected. The color Doppler ultrasound apparatus was used to detect BSD, PUVA, UVJ-M, and BND 3 months after delivery.Results:BND, PUVA-R, PUVA-S, and UVJ-M 3 months after delivery in the treatment groups were significantly lower than those in the control group, while BSD-S was significantly higher than that in the control group. The improvement of type I and Ⅱ muscle fiber fatigue (%), POP-Q degree, AP indication point (cm), and vaginal dynamic pressure (cmH2O) was significantly superior to that in the control group. The comparison of pelvic floor muscle strength classification before treatment between the two groups was not statistically significant. After treatment, the pelvic floor muscle in the two groups was significantly strengthened, and the proportion of V grade patients was significantly increased when compared with before treatment.Conclusions: The postpartum early pelvic floor rehabilitation technique can effectively enhance the pelvic floor function, and prevent the postpartum pelvic floor dysfunction, with an accurate efficacy;therefore, it deserves to be widely recommended in the clinic.

盆底四维超声评估电刺激生物反馈治疗PFD患者的效果分析

目的探讨盆底四维超声检查女性盆底肌功能障碍(PFD)患者经电刺激生物反馈治疗的应用价值。方法选取68例PFD患者,均开展电刺激生物反馈治疗,于治疗前后应用盆底四维超声进行检查,评估患者的临床效果。结果治疗后盆底肌力及盆底肌收缩压均高于治疗前,且1 h尿垫试验数据低于治疗前(P<0.05)。治疗后患者静息时、Valsalva动作时的提肛肌厚度高于治疗前,肛提肌裂孔左右径、肛提肌裂孔面积、膀胱后角均低于治疗前(P<0.05)。治疗后膀胱颈移动度及尿道旋转角均低于治疗前(P<0.05)。结论经电刺激生物反馈治疗前后应用盆底四维超声进行检查PFD患者能够有效明确机体的实际情况,进一步了解盆底肌功能,可为临床治疗提供科学依据。

不同时间段生物反馈电刺激结合盆底手法按摩对PFD患者盆底肌力及电生理的影响

目的探索不同时间段生物反馈结合盆底手法按摩对盆底功能障碍性疾病(pelvic floor dysfunction,PFD)患者盆底肌力和电生理的影响。方法选择PFD患者232例为研究对象,按照产后就诊并接受治疗时间段分为A组(产后6周~3个月内接受治疗)135例,B组(产后3~6个月内接受治疗)63例,C组(产后6个月~1年内接受治疗)34例。3组均接受1个疗程生物反馈电刺激及盆底手法按摩的联合治疗后,比较3组盆底肌力改变情况、PFD症状改善情况和电生理情况。结果治疗后,A组、B组Ⅰ类纤维肌力、Ⅱ类纤维肌力高于治疗前;且A组、B组盆底肌力高于C组(P<0.05)。A组、B组压力性尿失禁发生率低于治疗前,A组阴道前壁脱垂、子宫脱垂发生率低于治疗前;A组阴道前壁脱垂发生率低于B组和C组(P<0.05)。A组、B组Ⅰ类肌纤维疲劳度、Ⅱ类肌纤维疲劳度低于治疗前,阴道动态压力、A3反射正常率高于治疗前;A组和B组Ⅰ类纤维疲劳度、Ⅱ类纤维疲劳度低于C组,A3反射正常率高于C组(P<0.05)。结论PFD患者在产后6周~3个月接受生物反馈电刺激和手法按摩治疗效果最好,病程越长,治疗效果越差,需要后续进一步治疗。

Chinese expert consensus on primary prevention for pelvic floor dysfunction during pregnancy

Objective Pregnancy has been identified as a risk factor for pelvic floor dysfunction(PFD).The aim of this study was to establish primary prevention measures for PFD during pregnancy and reduce the overall incidence of PFD.Methods We assembled a panel of 36 experts,including gynecologists,obstetricians,and physiotherapists.Through surveys and expert meetings,the panel reviewed and assessed the safety and effectiveness of various clinical interventions.Based on expert comments from Round 1,a revised list of 8 clinical interventions was developed and submitted for a second round of expert review.Results A consensus was reached on the importance of implementing prevention measures to protect pelvic floor function during pregnancy.Experts particularly emphasized the significance of health education,weight management,pelvic floor muscle training,respiratory training,overall exercise,physical activity,and perineal massage.Conclusion The expert consensus provides comprehensive clinical measures to safeguard pelvic floor function during pregnancy.This paper represents the initial step toward developing scientific recommendations for pregnant women regarding the primary prevention of PFD.Future research should focus on the implementation of these recommendations in clinical practice.

Implementing of Electronic Medical Record in Pelvic Floor Ward: A Pilot Study

The electronic medical record is an essential technology tool to improve the quality of care. In present study we reported on the design and feasibility of electronic medical records in Female Pelvic Floor Dysfunction Ward. Our main goal was documentation with the least possible missed data, evidence-based decision making, documented active patient follow up and increasing patient’s satisfaction. The Electronic Registry System of Female Pelvic Floor Dysfunction (Vali e Asr Hospital, Tehran, Iran) was designed in mid 2014 and tested till March 2015. The software description was designed based on previous paper questionnaire used in this ward. The electronic questionnaires were filled in upon hospitalization and thereafter including follow ups. The questionnaire included 10 demographic and 15 main questions. A digital analog scale (1 - 10) in each part quantified the effects of problem on patient’s quality of life and also the effects of interventions as well. Entered information in each step was available for those with defined access. Reporting design was dependent on the needed data. Our supervised data entry was a guarantee to the quality of information with the least errors. Access to all para clinical data made rapid and evidence-based decision making. Patient satisfaction was achieved because of unified approach. The most interesting part was access to evidence-based results and data to be used in research projects. This study showed that EMRs in Female Pelvic Floor Dysfunction Wards could provide valuable information, improve the quality of care and increase patient’s satisfaction.

裸燕麦麸皮提取物和低频脉冲刺激干预PFD大鼠对ArfGAP3通路的影响

目的:分析裸燕麦麸皮提取物和低频脉冲刺激分别干预盆底功能障碍(PFD)大鼠对ADP核糖基化因子GTP结合蛋白3(ArfGAP3)信号通路的影响。方法:将30只大鼠随机均分为模型组、药物干预组、物理干预组,比较各组干预后病灶局部组织中ArfGAP3、透明质酸(HA)、层粘连蛋白(LN)、Ⅳ型胶原蛋白(Ⅳ-C)含量的统计学差异。用回归模型分析HA、LN、Ⅳ-C和ArfGAP3的综合关联。结果:药物干预组和模型组、物理干预组和模型组、物理干预组和药物干预组两两比较,各指标差异均有统计意义(P<0.05)。各指标对ArfGAP3蛋白影响程度依次为LN蛋白、HA蛋白、Ⅳ-C蛋白。结论:低频脉冲刺激和裸燕麦麸皮提取物虽然均能对PFD大鼠病灶局部ArfGAP3通路产生激活作用,但低频脉冲刺激物理治疗方式能更为快捷且显著的降低LN蛋白表达,增加HA、Ⅳ-C蛋白表达,可能对病灶局部肌功能恢复有更好促进作用。

Kegel运动对高龄PFD患者盆底功能、氧化应激指标水平及预后的影响

目的探索Kegel运动对高龄盆底功能障碍(PFD)患者盆底功能、氧化应激指标水平及预后的影响,以期为临床治疗提供参考。方法选取2019年11月—2021年2月在河南省平顶山市妇幼保健院就诊的115例PFD高龄产妇(产后42 d诊断为PFD)作为研究对象,采用随机数字表法将患者分为传统组(n=57)和Kegel组(n=58)。传统组患者采用传统盆底肌锻炼。Kegel组患者采用Kegel运动。比较2组患者治疗前、治疗6个月时盆底功能及丙二醛(MDA)、谷胱甘肽(GSH)、超氧化物歧化酶(SOD)水平。比较2组患者治疗6个月时不良结局发生情况。结果治疗前,2组患者阴道肌电压、阴道动态压、盆底肌力水平比较,差异无统计学意义(P>0.05)。治疗6个月时,2组患者阴道肌电压、阴道动态压、盆底肌力水平均高于治疗前,且Kegel组高于传统组,差异均有统计学意义(P<0.05)。治疗前,2组患者MDA、GSH及SOD水平比较,差异无统计学意义(P>0.05)。治疗6个月时,2组患者MDA水平均低于治疗前,且Kegel组低于传统组,差异均有统计学意义(P<0.05)。治疗6个月时,2组患者GSH及SOD水平均高于治疗前,且Kegel组高于传统组,差异均有统计学意义(P<0.05)。Kegel组患者中子宫脱垂、压力性尿失禁、腰骶酸痛、阴道松弛率、阴道干涩发生率均低于传统组,差异均有统计学意义(P<0.05)。结论Kegel运动应用于PFD患者治疗中,可增强阴道肌张力,改善氧化应激指标,调节盆底功能,改善患者临床预后,效果显著,值得临床推广应用。

围绝经期PFD患者阴道脱落细胞成熟度、E_(2)和25⁃(OH)⁃D与LGR7 mRNA的关系

目的探究围绝经期盆底功能障碍性疾病(PFD)患者阴道脱落细胞成熟度、雌激素(E_(2))和25羟基维生素D[25⁃(OH)⁃D]与阴道壁松弛素受体(LGR7)信使核糖核酸(mRNA)的关系。方法选取2020年9月至2022年9月于廊坊市人民医院就诊的围绝经期PFD患者42例,围绝经期健康女性38名,计算阴道脱落细胞成熟指数,检测血清E_(2)、25⁃(OH)⁃D水平以及阴道壁组织LGR7 mRNA相对表达量,分析LGR7 mRNA与其余指标的相关性。结果观察组绝经率、盆底肌静息肌电值、合并阴道炎率、LGR7 mRNA表达水平高于对照组,盆底肌最大收缩力、持续收缩力、阴道脱落细胞成熟度、E_(2)和25⁃(OH)⁃D水平低于对照组,差异均有统计学意义(P<0.05);阴道脱落细胞成熟度、E_(2)和25⁃(OH)⁃D均与盆底肌力呈正相关(P<0.05),LGR7 mRNA与盆底肌力,阴道脱落细胞成熟度、E_(2)和25⁃(OH)⁃D与LGR7 mRNA呈负相关(P<0.05);阴道脱落细胞成熟度、E_(2)、25⁃(OH)⁃D、LGR7 mRNA的曲线下面积分别为0.918、0.919、0.898、0.858(P<0.05);阴道脱落细胞成熟度<58.95%、E_(2)<65.76 pmol/L、25⁃(OH)⁃D<28.19μg/L、LGR7 mRNA>0.58为围绝经期PFD的危险因素(P<0.05)。结论围绝经期PFD患者阴道脱落细胞成熟度、E_(2)和25⁃(OH)⁃D与LGR7 mRNA呈负相关,上述指标均对PFD的诊断具有一定参考价值。

经会阴盆底超声参数对盆底功能障碍性疾病的监测效果及对盆底康复治疗的指导价值

目的探究经会阴盆底超声参数对盆底功能障碍性疾病(PFD)的监测效果及对盆底康复治疗的指导价值。方法选取2021年1月至2022年6月江苏省连云港市妇幼保健院119例产后42 d发现的PFD患者作为研究对象,根据分娩情况分为初产妇组(n=59)和经产妇组(n=60)。比较两组及不同分娩方式患者盆底超声参数,所有患者均行盆底康复治疗,治疗1个月后统计疗效,分析各参数预测疗效的价值。结果经产妇组尿道旋转角、膀胱后角、膀胱移动度、肛提肌裂孔面积(最大Valsalva动作)均高于初产妇组(P<0.05);两组中自然分娩孕妇尿道旋转角、膀胱后角、膀胱移动度、肛提肌裂孔面积(最大Valsalva动作)均高于剖宫产孕妇(P<0.05);疗效不佳的PFD患者治疗前的尿道旋转角、膀胱后角、膀胱移动度、肛提肌裂孔面积(最大Valsalva动作)均高于疗效良好的患者(P<0.05)。治疗前尿道旋转角、膀胱后角、膀胱移动度、肛提肌裂孔面积(最大Valsalva动作)预测PFD患者盆底康复疗效不佳的曲线下面积(AUC)分别为0.821、0.771、0.732、0.703。结论经会阴盆底超声参数可监测PFD病情,且能为临床预测盆底康复疗效、判断疾病转归提供参考。

女性盆底功能障碍性疾病诊治流程及物理康复技术临床应用——临床应用及实践

盆底肌训练、生物反馈、电刺激、磁刺激、射频、激光等物理康复技术现已证实在女性盆底功能障碍性疾病(FPFD)的临床治疗中有一定疗效,且在相关类型FPFD诊治指南中获得一定推荐或不同强度证据支持。物理康复技术相关参数在同一种FPFD的治疗中虽不具有一致性,但均在一定参数范围内。本综述旨在探究物理康复技术的相关循证依据,对重点类型FPFD推荐相应物理参数的物理治疗,从而对不同类型物理治疗技术在FPFD的治疗提供借鉴和依据。

女性盆底功能障碍性疾病诊治流程及物理治疗康复临床应用——康复流程、原则及智能诊疗

女性盆底功能障碍性疾病(FPFD)发生机制复杂,专科的临床医师往往无法覆盖妇产、泌尿、肛肠、影像等各专科全面的医学专业信息,限制了对于该疾病的系统、全面诊治。FPFD的治疗需要遵循康复流程,制定个性化物理治疗干预措施,同时结合其他方式制定综合性治疗策略。人工智能在盆底领域的应用,不仅可以提高医生诊断效率,还可以为综合治疗方案的制定提供参考和依据,实现智能诊疗与精准医疗。本文从FPFD康复流程出发,分析康复原则及内容,探究人工智能在FPFD诊疗中的应用现状,旨在为实现盆底疾病智能诊疗提供参考。

基于MRI及DTI双模态成像技术在盆底肌功能障碍诊断中的临床价值

目的 探究基于磁共振成像(MRI)及扩散张量成像(DTI)双模态成像技术在盆底肌功能障碍(PFD)诊断中的临床价值。方法选取喀什地区第一人民医院收治的50例PFD患者作为研究对象并纳入PFD组,另选取同期于医院体检的30例正常志愿者作为对照,纳入对照组,两组均采用MRI及DTI双模态成像技术进行检查,比较两组患者临床资料、盆底肌扫描面积(髂骨尾骨肌、耻骨尾骨肌、耻骨直肠肌)、肛提肌裂孔宽度、盆底标志线(H线、M线)、髂骨尾骨肌厚度(ICT)、髂骨尾骨肌角(ICA)及肛提肌角(LPA),髂骨尾骨肌、耻骨直肠肌各向异性分数(FA)及表观弥散系数(ADC)值。结果两组一般资料比较在统计学上无显著性差异(P>0.05);PFD组静态与动态髂骨尾骨肌、耻骨尾骨肌、耻骨直肠肌面积均小于对照组(P<0.05);PFD组静态与动态肛提肌裂孔宽度大于对照组,H线、M线长于对照组(P<0.05);PFD组ICT少于对照组,LPA大于对照组,两组ICA比较在统计学上无显著性差异(P>0.05);两组髂骨尾骨肌、耻骨直肠肌FA、ADC值比较在统计学上无显著性差异(P>0.05)。结论基于MRI及DTI双模态成像技术可反映PFD患者盆底功能及形态变化,在PFD患者中具有良好的应用价值,可用于临床推广。

综合干预联合盆底康复治疗对围绝经期女性盆底功能障碍性疾病的影响

目的:探讨综合干预联合盆底康复治疗对围绝经期女性盆底功能障碍性疾病(PFD)的影响。方法:选取2021年10月—2022年12月贵州航天医院收治的160例围绝经期PFD患者作为研究对象,以随机数字表法分为研究组与对照组,各80例。对照组实施盆底肌康复治疗,研究组在对照组基础上进行综合干预。比较两组干预效果。结果:研究组总有效率高于对照组,差异有统计学意义(P=0.043)。干预6、12周后,两组Ⅰ、Ⅱ类肌纤维疲劳度和盆底功能评分逐渐降低,且研究组低于对照组,两组Ⅰ、Ⅱ类肌纤维电压值逐渐升高,且研究组高于对照组,差异有统计学意义(P<0.05)。结论:综合干预联合盆底康复治疗对围绝经期女性PFD的干预效果显著,可改善盆底肌疲劳度、电压值、盆底功能。

经会阴盆底超声定量评估围绝经期子宫全切术后近期盆底功能的价值

目的经会阴盆底超声动态观察围绝经期子宫切除术后盆底结构变化,并定量评估其近期盆底功能。方法选择2021年1月—2023年3月在徐州市妇幼保健院超声科因子宫良性病变行子宫全切术后1年内复查的62例患者作为观察者设为子宫切除组,年龄40~55岁,术前未绝经,术前无盆腔手术史,术前临床未诊断盆底功能障碍性疾病(pelvic floor dysfunction,PFD);选择同期在本院经会阴盆底超声检查前临床未诊断PFD的61名女性作为对照组,年龄40~54岁,未绝经,无盆腔手术史。所有检查者均由科室2名盆底研究方向副主任医师随机分配操作检查。所有受检者行经会阴盆底超声检查,在标准切面上测量膀胱逼尿肌厚度、静息状态及最大Valsalva状态下膀胱颈距离耻骨联合后下缘距离(X)、膀胱尿道后角(β)、直肠壶腹最低点距耻骨联合后下缘距离(D),观察尿道内口漏斗形成,计算尿道旋转角(Ra)及膀胱颈下降值(bladder neck descent,BND),并观察前后盆腔有无器官脱垂及程度。结果子宫切除组患者年龄较对照组大,有统计学意义(P<0.05),X、D值均减小,差异均有统计学意义(P<0.05);而Ra、β、BND、膀胱逼尿肌厚度及裂孔面积比较差异均无统计学意义(P>0.05);子宫切除组与对照组发生PFD的情况比较,仅直肠脱垂差异有统计学意义(P<0.05),压力性尿失禁(stress urinary incontinence,SUI)、膀胱脱垂、盆腔器官脱垂(pelvic organ prolapse,POP)总计及PFD总计比较差异均无统计学意义(P>0.05)。结论经会阴盆底超声可对围绝经期子宫切除术后盆底结构动态观察,并进行定量评估;子宫切除术对围绝经期女性后盆腔盆底功能影响较大。

高分辨率MRI对盆底功能障碍性疾病患者子宫形态改变的评估价值

目的探讨高分辨率MRI对盆底功能障碍性疾病患者子宫形态改变的评估应用价值,以期为临床诊断该疾病提供参考和依据。方法本研究中共纳入83例盆底功能障碍性疾病患者,所有患者均来源于河南科技大学第二附属医院,选取时间为2020年10月至2022年10月,均经手术确诊,设为研究组,另于同一时间段选择于本院进行健康体检的80例研究对象,设为参照组,进行回顾性分析。所有研究对象均于术前接受高分辨率MRI及会阴实时三维超声扫描。将两组研究对象应用高分辨率MRI检查的各项指标、应用三维超声检查的各项指标,以及盆底肌厚度进行对比。结果研究组患者膀胱颈下降、子宫颈下降、肛管直肠连接下降各项数值均比参照组研究对象升高(均P<0.05);研究组患者膀胱移动度、Valsalva盆膈裂孔面积均相较于参照组上升,子宫后位占比为71.08%,相较于参照组的28.80%升高,子宫前位占比为28.92%,相较于参照组的71.25%下降(均P<0.05);经对比,参照组和研究组研究对象左右侧耻骨直肠肌、髂骨尾骨肌厚度对比,均有统计学差异,其中研究组患者左、右侧耻骨直肠肌、髂骨尾骨肌厚度均比参照低,且两组研究对象之间对比,左侧耻骨直肠肌、髂骨尾骨肌厚度均比右侧升高(均P<0.05)。结论盆底功能障碍性疾病患者接受高分辨率MRI检查和会阴三维实时超声检查均可为该疾病的诊断提供参考和依据,且高分辨率MRI检查具有较高的应用价值,临床在对盆底功能障碍性疾病患者诊断时,可首选会阴三维实时超声检查方法,而对于行上述检查未见明显征象的患者,可行高分辨率MRI检查,从而提升诊断的准确率。