Wave equation wave field numerical modeling technology is applied to the observation that deep layer imaging is difficult below a screening layer of high-velocity basalt. Three simple high-velocity basalt models are d...Wave equation wave field numerical modeling technology is applied to the observation that deep layer imaging is difficult below a screening layer of high-velocity basalt. Three simple high-velocity basalt models are designed on the basis of basalt formation characteristics. The analysis of deep-layer reflection seismic signal energy shows that lowfrequency seismic signals are capable of both penetrating the thin high-velocity basalt layer and reducing the diffraction noise caused by the rough surfaces. The simulation experiment of a complete 2D basalt model confirms that the low-frequency signals can be used to boost the quality of deep-layer imaging under the high-velocity basalt layer and achieve good results in low-pass filter processing of actual data.展开更多
Worker honeybee pierces animal or human skin with its ultra-sharp stinger and injects venom to defend itself. The insertion behavior is a painless transdermal drug delivery process. In this study, Apis cerana cerana w...Worker honeybee pierces animal or human skin with its ultra-sharp stinger and injects venom to defend itself. The insertion behavior is a painless transdermal drug delivery process. In this study, Apis cerana cerana worker honeybee was chosen as the research object. The geometry and structure of the stinger were observed by the Scanning Electron Microscope （SEM）. High-speed video imaging technique was adopted to observe the stinger insertion and pull behavior of honeybee. The skin insertion, pull-out, in-plane buckling and out-of-plane bending forces of honeybee stinger were tested by a self-developed mechanical loading equipment. Results showed that the honeybee stinger pierces directly into skin without frequent vibration. The pull-out force （average 136.04 mN） was two orders of magnitude higher than the penetration force （average 1.34mN）. Compared with the penetration force, the in-plane buckling force （average 6.72 mN） was in the same order of magnitude. The result of out-of-plane bending test showed that the stinger was elastic and it could recover after bending. The excellent geometry and structure of honeybee stinger will provide an inspiration for the further improved design ofmicroneedle-based transdermal drug delivery system.展开更多
文摘Wave equation wave field numerical modeling technology is applied to the observation that deep layer imaging is difficult below a screening layer of high-velocity basalt. Three simple high-velocity basalt models are designed on the basis of basalt formation characteristics. The analysis of deep-layer reflection seismic signal energy shows that lowfrequency seismic signals are capable of both penetrating the thin high-velocity basalt layer and reducing the diffraction noise caused by the rough surfaces. The simulation experiment of a complete 2D basalt model confirms that the low-frequency signals can be used to boost the quality of deep-layer imaging under the high-velocity basalt layer and achieve good results in low-pass filter processing of actual data.
基金Acknowledgment This research is financially supported by the National Nature Science Foundation of China （No. 51205423, No. 51205138, and No. 51575543）.
文摘Worker honeybee pierces animal or human skin with its ultra-sharp stinger and injects venom to defend itself. The insertion behavior is a painless transdermal drug delivery process. In this study, Apis cerana cerana worker honeybee was chosen as the research object. The geometry and structure of the stinger were observed by the Scanning Electron Microscope （SEM）. High-speed video imaging technique was adopted to observe the stinger insertion and pull behavior of honeybee. The skin insertion, pull-out, in-plane buckling and out-of-plane bending forces of honeybee stinger were tested by a self-developed mechanical loading equipment. Results showed that the honeybee stinger pierces directly into skin without frequent vibration. The pull-out force （average 136.04 mN） was two orders of magnitude higher than the penetration force （average 1.34mN）. Compared with the penetration force, the in-plane buckling force （average 6.72 mN） was in the same order of magnitude. The result of out-of-plane bending test showed that the stinger was elastic and it could recover after bending. The excellent geometry and structure of honeybee stinger will provide an inspiration for the further improved design ofmicroneedle-based transdermal drug delivery system.
