选用酵母细胞为微胶囊壁材,对制备薄荷油微胶囊的工艺条件进行了研究,采用单因素试验探索芯壁比、包埋温度、包埋时间、加水量等微胶囊化条件对薄荷油包埋率的影响,在此基础上采用响应面分析法优化微胶囊化条件,得到具有显著性的拟合回...选用酵母细胞为微胶囊壁材,对制备薄荷油微胶囊的工艺条件进行了研究,采用单因素试验探索芯壁比、包埋温度、包埋时间、加水量等微胶囊化条件对薄荷油包埋率的影响,在此基础上采用响应面分析法优化微胶囊化条件,得到具有显著性的拟合回归方程。试验结果表明:酵母细胞对薄荷油进行微胶囊化的最优条件为:包埋温度48℃,包埋时间6 h,加水量13 m L/g。在此条件下得到薄荷油的最优包埋率为57.33%,与预测值十分接近,薄荷油已被包入酵母壁材内。展开更多
Fish oil microcapsules were prepared using two natural polysaccharides, alginate and chitosan, as the wall materials. A response surface methodology (RSM) was used to optimize the conditions for fish oil encapsulati...Fish oil microcapsules were prepared using two natural polysaccharides, alginate and chitosan, as the wall materials. A response surface methodology (RSM) was used to optimize the conditions for fish oil encapsulation efficiency (FOEE). The FOEE was investigated with respect to three key-variables in the RSM: ratio of inner oil phase to aqueous phase (X1 w/w); concentration of the aqueous phase (X2, wt%); and ratio of the aqueous phase to outer oil phase (X3, v/v). The optimal formulation obtained from the RSM model, i.e., 2.7:1 (X1), 1.6 wt% (X2), and 11.5:1 (X3), gave a FOEE of 28%. The model was validated and the fish oil microcapsules prepared under the optimized conditions were characterized in terms of particle size, polydispersity index (PDI), zeta potential, surface morphology, and in vitro release. The average droplet size, PDI, and zeta potential were 915 nm, 0.038, and +5.2 mV, respectively. The fish oil microcapsules were highly uniform microspheres, and had an accumulative release rate of 77.7% in 270 min in a gastrointestinal model, indicating their potential as an alternative carrier for the controlled release of fish oil. In conclusion, formulating optimal microencapsulation conditions by the RSM can be applied to the microencapsulation of various oil-soluble nutrients for food applications.展开更多
文摘选用酵母细胞为微胶囊壁材,对制备薄荷油微胶囊的工艺条件进行了研究,采用单因素试验探索芯壁比、包埋温度、包埋时间、加水量等微胶囊化条件对薄荷油包埋率的影响,在此基础上采用响应面分析法优化微胶囊化条件,得到具有显著性的拟合回归方程。试验结果表明:酵母细胞对薄荷油进行微胶囊化的最优条件为:包埋温度48℃,包埋时间6 h,加水量13 m L/g。在此条件下得到薄荷油的最优包埋率为57.33%,与预测值十分接近,薄荷油已被包入酵母壁材内。
文摘Fish oil microcapsules were prepared using two natural polysaccharides, alginate and chitosan, as the wall materials. A response surface methodology (RSM) was used to optimize the conditions for fish oil encapsulation efficiency (FOEE). The FOEE was investigated with respect to three key-variables in the RSM: ratio of inner oil phase to aqueous phase (X1 w/w); concentration of the aqueous phase (X2, wt%); and ratio of the aqueous phase to outer oil phase (X3, v/v). The optimal formulation obtained from the RSM model, i.e., 2.7:1 (X1), 1.6 wt% (X2), and 11.5:1 (X3), gave a FOEE of 28%. The model was validated and the fish oil microcapsules prepared under the optimized conditions were characterized in terms of particle size, polydispersity index (PDI), zeta potential, surface morphology, and in vitro release. The average droplet size, PDI, and zeta potential were 915 nm, 0.038, and +5.2 mV, respectively. The fish oil microcapsules were highly uniform microspheres, and had an accumulative release rate of 77.7% in 270 min in a gastrointestinal model, indicating their potential as an alternative carrier for the controlled release of fish oil. In conclusion, formulating optimal microencapsulation conditions by the RSM can be applied to the microencapsulation of various oil-soluble nutrients for food applications.