This article explored the definition, dimensions, and building mechanisms of drug regulatory capabilities（DRC） and their relationship with regulatory performance. Based on the theories on organizational capability a...This article explored the definition, dimensions, and building mechanisms of drug regulatory capabilities（DRC） and their relationship with regulatory performance. Based on the theories on organizational capability and their application in public sector, interviews with officers from drug regulatory agencies and analysis of its three determinations, the DRC was defined as the follows： a learned pattern through which the drug regulatory agencies acquire, reconstruct and utilize organizational resources to protect and advance public health. DRC can be divided into different dimensions and structured as the basic capabilities and functional capabilities. This research also introduced three learning mechanisms for DRC construction, which include learning by doing, organizational learning, and exploratory learning. Finally, a qualitative case study of drug application and approval in China was conducted to explore the relationship between regulatory capabilities and performance.展开更多
The capacitance performances of poly（3,4-ethylenedioxythiophene）-poly（styrenesulfonate）（PEDOT-PSS） supramolecular hydrogels have been investigated systematically. The materials show a specific capacitance of 67 ...The capacitance performances of poly（3,4-ethylenedioxythiophene）-poly（styrenesulfonate）（PEDOT-PSS） supramolecular hydrogels have been investigated systematically. The materials show a specific capacitance of 67 F/g and display excellent rate capability at the scan rate as high as 5000 m V/s in the cyclic voltammogram measurements, accompanied by good cycle stability. On the basis of the measurements of the microscale morphologies, specific areas and electrical conductivities, the mechanisms for the improvement of the electrochemical properties are discussed and ascribed to the novel porous microstructures of the hydrogels and the synergetic effect of the rigid PEDOT and soft PSS components. Furthermore, polyaniline（PAn） is compounded with the PEDOT-PSS hydrogels through an interfacial polymerization process, endowing the hydrogel materials with a higher specific capacitance of 160 F/g at the scan rate of 5000 m V/s. The significance of this work lies in the demonstration of a novel method to solve the problems of conducting polymers in electrochemical applications.展开更多
文摘This article explored the definition, dimensions, and building mechanisms of drug regulatory capabilities（DRC） and their relationship with regulatory performance. Based on the theories on organizational capability and their application in public sector, interviews with officers from drug regulatory agencies and analysis of its three determinations, the DRC was defined as the follows： a learned pattern through which the drug regulatory agencies acquire, reconstruct and utilize organizational resources to protect and advance public health. DRC can be divided into different dimensions and structured as the basic capabilities and functional capabilities. This research also introduced three learning mechanisms for DRC construction, which include learning by doing, organizational learning, and exploratory learning. Finally, a qualitative case study of drug application and approval in China was conducted to explore the relationship between regulatory capabilities and performance.
基金financially supported by the National Natural Science Foundation of China(Nos.21174059 and 21374046)China Postdoctoral Science Foundation(No.2013M530249)+1 种基金Program for Changjiang Scholars and Innovative Research Teams in Universities,Open Project of State Key Laboratory of Superamolecular Structure and Materials(No.SKLSSM201416)the Testing Foundation of Nanjing University
文摘The capacitance performances of poly（3,4-ethylenedioxythiophene）-poly（styrenesulfonate）（PEDOT-PSS） supramolecular hydrogels have been investigated systematically. The materials show a specific capacitance of 67 F/g and display excellent rate capability at the scan rate as high as 5000 m V/s in the cyclic voltammogram measurements, accompanied by good cycle stability. On the basis of the measurements of the microscale morphologies, specific areas and electrical conductivities, the mechanisms for the improvement of the electrochemical properties are discussed and ascribed to the novel porous microstructures of the hydrogels and the synergetic effect of the rigid PEDOT and soft PSS components. Furthermore, polyaniline（PAn） is compounded with the PEDOT-PSS hydrogels through an interfacial polymerization process, endowing the hydrogel materials with a higher specific capacitance of 160 F/g at the scan rate of 5000 m V/s. The significance of this work lies in the demonstration of a novel method to solve the problems of conducting polymers in electrochemical applications.
