Objective: To explore the correlation of menopausal index with sex hormones, lipid metabolism and cytokines in perimenopausal women. Methods: A total of 208 perimenopausal women who were treated in this hospital betwe...Objective: To explore the correlation of menopausal index with sex hormones, lipid metabolism and cytokines in perimenopausal women. Methods: A total of 208 perimenopausal women who were treated in this hospital between September 2015 and March 2018 were selected as the perimenopausal group and 150 healthy young women (20-30 years old) who received physical examination in this hospital during the same period were selected as the control group. The differences in the levels of Kupperman menopausal index as well as the contents of sex hormones, lipid metabolism indexes and inflammatory factors were compared between the two groups. Results: Kupperman menopausal index of perimenopausal group was higher than that of control group;sex hormones E2, P and T contents were lower than those of control group whereas FSH content was higher than that of control group;lipid metabolism indexes TC and LDL-C contents were higher than those of control group whereas HDL-C content was lower than that of control group;inflammatory factors IL-1β, IL-2, IL-18 and IFN-γ contents were higher than those of control group;the Kupperman menopausal index of perimenopausal women was negatively correlated with E2, P, T and HDL-C contents, and positively correlated with FSH, TC, LDL-C, IL-1β, IL-2, IL-18 and IFN-γ contents. Conclusion: The Kupperman menopausal index in perimenopausal women abnormally increases, and the specific level is directly correlated with the female sex hormones, lipid metabolism disorder and systemic microinflammation.展开更多
目的了解贵阳市男男性行为者(men who have sex with men,MSM)焦虑、抑郁现状,分析MSM焦虑、抑郁的相关影响因素。方法通过方便抽样法招募MSM,问卷收集MSM人口学、性相关特征与行为、其他健康相关行为信息;采用社会支持量表、焦虑自评...目的了解贵阳市男男性行为者(men who have sex with men,MSM)焦虑、抑郁现状,分析MSM焦虑、抑郁的相关影响因素。方法通过方便抽样法招募MSM,问卷收集MSM人口学、性相关特征与行为、其他健康相关行为信息;采用社会支持量表、焦虑自评量表和抑郁自评量表测评MSM的社会支持、焦虑和抑郁;进行人类免疫缺陷病毒(human immunodeficiency virus,HIV)抗体血清学检测;利用SPSS 20.0软件建立多因素logistic回归模型分析MSM焦虑、抑郁的影响因素。结果共计招募到420名MSM,合格问卷403份,合格率为95.95%;MSM焦虑、抑郁检出率分别为23.82%、32.51%;多因素logistic回归分析结果显示,最近1周是否发生同性肛交性行为、最近1个月平均每天吸烟量、社会支持是MSM焦虑的影响因素;月收入、最近1个月平均每天吸烟量、社会支持是MSM抑郁的影响因素。结论贵阳市MSM人群中有一定比例的轻度焦虑、抑郁症状患者,焦虑、抑郁与收入、性相关行为、吸烟、社会支持有关。展开更多
文摘Objective: To explore the correlation of menopausal index with sex hormones, lipid metabolism and cytokines in perimenopausal women. Methods: A total of 208 perimenopausal women who were treated in this hospital between September 2015 and March 2018 were selected as the perimenopausal group and 150 healthy young women (20-30 years old) who received physical examination in this hospital during the same period were selected as the control group. The differences in the levels of Kupperman menopausal index as well as the contents of sex hormones, lipid metabolism indexes and inflammatory factors were compared between the two groups. Results: Kupperman menopausal index of perimenopausal group was higher than that of control group;sex hormones E2, P and T contents were lower than those of control group whereas FSH content was higher than that of control group;lipid metabolism indexes TC and LDL-C contents were higher than those of control group whereas HDL-C content was lower than that of control group;inflammatory factors IL-1β, IL-2, IL-18 and IFN-γ contents were higher than those of control group;the Kupperman menopausal index of perimenopausal women was negatively correlated with E2, P, T and HDL-C contents, and positively correlated with FSH, TC, LDL-C, IL-1β, IL-2, IL-18 and IFN-γ contents. Conclusion: The Kupperman menopausal index in perimenopausal women abnormally increases, and the specific level is directly correlated with the female sex hormones, lipid metabolism disorder and systemic microinflammation.
文摘目的了解贵阳市男男性行为者(men who have sex with men,MSM)焦虑、抑郁现状,分析MSM焦虑、抑郁的相关影响因素。方法通过方便抽样法招募MSM,问卷收集MSM人口学、性相关特征与行为、其他健康相关行为信息;采用社会支持量表、焦虑自评量表和抑郁自评量表测评MSM的社会支持、焦虑和抑郁;进行人类免疫缺陷病毒(human immunodeficiency virus,HIV)抗体血清学检测;利用SPSS 20.0软件建立多因素logistic回归模型分析MSM焦虑、抑郁的影响因素。结果共计招募到420名MSM,合格问卷403份,合格率为95.95%;MSM焦虑、抑郁检出率分别为23.82%、32.51%;多因素logistic回归分析结果显示,最近1周是否发生同性肛交性行为、最近1个月平均每天吸烟量、社会支持是MSM焦虑的影响因素;月收入、最近1个月平均每天吸烟量、社会支持是MSM抑郁的影响因素。结论贵阳市MSM人群中有一定比例的轻度焦虑、抑郁症状患者,焦虑、抑郁与收入、性相关行为、吸烟、社会支持有关。
