目的评估择期肝切除术与肝射频消融术患者围手术期血浆IL-6、IL-10、CRP的水平,探讨2种手术方式围手术期炎症反应程度及其与短期预后的关系。方法纳入37例肝占位患者为研究对象,其中择期肝切除术19例、肝射频消融术18例。采用ELISA法检...目的评估择期肝切除术与肝射频消融术患者围手术期血浆IL-6、IL-10、CRP的水平,探讨2种手术方式围手术期炎症反应程度及其与短期预后的关系。方法纳入37例肝占位患者为研究对象,其中择期肝切除术19例、肝射频消融术18例。采用ELISA法检测患者术前、术毕及术后不同时间点血浆IL-6、IL-10、CRP水平,通过非参数检验判断治疗前后的动态变化,并比较2种手术方式围手术期炎症因子水平及预后指标。结果治疗前后肝切除术患者围手术期血浆IL-6、IL-10、CRP水平及肝射频消融术患者IL-6、CRP水平均存在动态变化(均P<0.05)。肝切除术后24 h及48 h的IL-6,术毕IL-10,术后24、48、72 h CRP水平均显著高于术前(均P<0.05);肝射频消融术术毕IL-6水平显著高于术前(P<0.05),IL-10、CRP水平在手术前后的差异均无统计学意义(均P>0.05)。与肝切除术患者比较,射频消融术术后48 h CRP水平降低,术后住院时间缩短(均P<0.05)。结论肝射频消融术后全身炎症反应程度相对较小,可能有利于患者加速康复。展开更多
目的探讨不同时期难治性支原体肺炎(refractory mycoplasma pneumoniae pneumonia,RMPP)患儿支气管肺泡灌洗液中表面活性物质相关蛋白-A(surfactant protein A,SPA)的表达水平及与肺功能的关系。方法选取2021年1月—2023年1月南通市第...目的探讨不同时期难治性支原体肺炎(refractory mycoplasma pneumoniae pneumonia,RMPP)患儿支气管肺泡灌洗液中表面活性物质相关蛋白-A(surfactant protein A,SPA)的表达水平及与肺功能的关系。方法选取2021年1月—2023年1月南通市第一人民医院收治的62例RMPP患儿为对象,以同期行支气管镜异物取出术且无肺部感染的50例患儿为对照组。RMPP患儿于急性期、恢复期行支气管肺泡灌洗液中SPA检测以及肺功能指标检测[第1秒用力呼气容积(forced expiratory volume in one second,FEV_(1))、用力肺活量(forced vital capacity,FVC)、FEV_(1)/FVC],对照组同样如此。比较三者检测结果差异,使用Pearson分析RMPP患儿支气管肺泡灌洗液中SPA水平与肺功能指标的相关性。结果RMPP患儿肺泡灌洗液中的SPA急性期(59.82±12.64)μg/L、恢复期(129.91±24.86)μg/L高于对照组,差异有统计学意义(P<0.05)。RMPP急性期、RMPP恢复期的FEV_(1)、FVC、FEV_(1)/FVC(80.95±6.88)%、(88.41±5.75)%较对照组低,差异有统计学意义(P<0.05);RMPP患儿于急性期时肺泡灌洗液中的SPA较恢复期低,FEV_(1)、FVC、FEV_(1)/FVC较恢复期低,差异有统计学意义(P<0.05);RMPP患儿肺泡灌洗液中SPA水平与FEV_(1)、FVC、FEV_(1)/FVC呈正相关(P<0.05)。结论RMPP患儿病情处于急性发展阶段的情况下其支气管肺泡灌洗液中的SPA表达相较病情恢复阶段更低,同时RMPP患儿支气管肺泡灌洗液中SPA水平与其肺功能指标呈正相关性。展开更多
The nutritional status of Chinese residents has been greatly improved during the past 50 years.Compared with Japanese people to whom our food consumption habit is similar,the calorie nutrient intake and fat nutrient i...The nutritional status of Chinese residents has been greatly improved during the past 50 years.Compared with Japanese people to whom our food consumption habit is similar,the calorie nutrient intake and fat nutrient intake per capita of Chinese residents has exceeded the intake of the Japanese residents,but the protein nutrient intake is still lower.Among the composition of the calorie nutrient,the proportion of fat is higher,but the proportion of protein is lower,and both the animal protein and the vegetable fat are small.Therefore,we should guide the poor to the rational consumption such as soybean which contains quality protein but is a kind of inexpensive food.With the increase of population eating out,residents＇ nutrients awareness as well as the public service institutions knowledge of nutrition should be enhanced.展开更多
文摘目的评估择期肝切除术与肝射频消融术患者围手术期血浆IL-6、IL-10、CRP的水平,探讨2种手术方式围手术期炎症反应程度及其与短期预后的关系。方法纳入37例肝占位患者为研究对象,其中择期肝切除术19例、肝射频消融术18例。采用ELISA法检测患者术前、术毕及术后不同时间点血浆IL-6、IL-10、CRP水平,通过非参数检验判断治疗前后的动态变化,并比较2种手术方式围手术期炎症因子水平及预后指标。结果治疗前后肝切除术患者围手术期血浆IL-6、IL-10、CRP水平及肝射频消融术患者IL-6、CRP水平均存在动态变化(均P<0.05)。肝切除术后24 h及48 h的IL-6,术毕IL-10,术后24、48、72 h CRP水平均显著高于术前(均P<0.05);肝射频消融术术毕IL-6水平显著高于术前(P<0.05),IL-10、CRP水平在手术前后的差异均无统计学意义(均P>0.05)。与肝切除术患者比较,射频消融术术后48 h CRP水平降低,术后住院时间缩短(均P<0.05)。结论肝射频消融术后全身炎症反应程度相对较小,可能有利于患者加速康复。
文摘目的探讨不同时期难治性支原体肺炎(refractory mycoplasma pneumoniae pneumonia,RMPP)患儿支气管肺泡灌洗液中表面活性物质相关蛋白-A(surfactant protein A,SPA)的表达水平及与肺功能的关系。方法选取2021年1月—2023年1月南通市第一人民医院收治的62例RMPP患儿为对象,以同期行支气管镜异物取出术且无肺部感染的50例患儿为对照组。RMPP患儿于急性期、恢复期行支气管肺泡灌洗液中SPA检测以及肺功能指标检测[第1秒用力呼气容积(forced expiratory volume in one second,FEV_(1))、用力肺活量(forced vital capacity,FVC)、FEV_(1)/FVC],对照组同样如此。比较三者检测结果差异,使用Pearson分析RMPP患儿支气管肺泡灌洗液中SPA水平与肺功能指标的相关性。结果RMPP患儿肺泡灌洗液中的SPA急性期(59.82±12.64)μg/L、恢复期(129.91±24.86)μg/L高于对照组,差异有统计学意义(P<0.05)。RMPP急性期、RMPP恢复期的FEV_(1)、FVC、FEV_(1)/FVC(80.95±6.88)%、(88.41±5.75)%较对照组低,差异有统计学意义(P<0.05);RMPP患儿于急性期时肺泡灌洗液中的SPA较恢复期低,FEV_(1)、FVC、FEV_(1)/FVC较恢复期低,差异有统计学意义(P<0.05);RMPP患儿肺泡灌洗液中SPA水平与FEV_(1)、FVC、FEV_(1)/FVC呈正相关(P<0.05)。结论RMPP患儿病情处于急性发展阶段的情况下其支气管肺泡灌洗液中的SPA表达相较病情恢复阶段更低,同时RMPP患儿支气管肺泡灌洗液中SPA水平与其肺功能指标呈正相关性。
基金Supported by Educational Department Doctoral Station Fund Program(20070307057)~~
文摘The nutritional status of Chinese residents has been greatly improved during the past 50 years.Compared with Japanese people to whom our food consumption habit is similar,the calorie nutrient intake and fat nutrient intake per capita of Chinese residents has exceeded the intake of the Japanese residents,but the protein nutrient intake is still lower.Among the composition of the calorie nutrient,the proportion of fat is higher,but the proportion of protein is lower,and both the animal protein and the vegetable fat are small.Therefore,we should guide the poor to the rational consumption such as soybean which contains quality protein but is a kind of inexpensive food.With the increase of population eating out,residents＇ nutrients awareness as well as the public service institutions knowledge of nutrition should be enhanced.
