期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
Pulsed electrical stimulation protects neurons in the dorsal root and anterior horn of the spinal cord after peripheral nerve injury 被引量:3
1
作者 Bao-an Pei Jin-hua Zi +2 位作者 Li-sheng Wu Cun-hua Zhang Yun-zhen Chen 《Neural Regeneration Research》 SCIE CAS CSCD 2015年第10期1650-1655,共6页
Most studies on peripheral nerve injury have focused on repair at the site of injury, but very few have examined the effects of repair strategies on the more proximal neuronal cell bodies. In this study, an approximat... Most studies on peripheral nerve injury have focused on repair at the site of injury, but very few have examined the effects of repair strategies on the more proximal neuronal cell bodies. In this study, an approximately 10-mm-long nerve segment from the ischial tuberosity in the rat was transected and its proximal and distal ends were inverted and sutured. The spinal cord was subjected to pulsed electrical stimulation at T10 and L3, at a current of 6.5 m A and a stimulation frequency of 15 Hz, 15 minutes per session, twice a day for 56 days. After pulsed electrical stimulation, the number of neurons in the dorsal root ganglion and anterior horn was increased in rats with sciatic nerve injury. The number of myelinated nerve fibers was increased in the sciatic nerve. The ultrastructure of neurons in the dorsal root ganglion and spinal cord was noticeably improved. Conduction velocity of the sciatic nerve was also increased. These results show that pulsed electrical stimulation protects sensory neurons in the dorsal root ganglia as well as motor neurons in the anterior horn of the spinal cord after peripheral nerve injury, and that it promotes the regeneration of peripheral nerve fibers. 展开更多
关键词 nerve regeneration peripheral nerve pulsed electrical stimulation spinal cord neurons dorsal root ganglion nerve conduction neural regeneration
下载PDF
Supplementary motor area deactivation impacts the recovery of hand function from severe peripheral nerve injury 被引量:1
2
作者 Ye-chen Lu Han-qiu Liu +4 位作者 Xu-yun Hua Yun-dong Shen Wen-dong Xu Jian-guang Xu Yu-dong Gu 《Neural Regeneration Research》 SCIE CAS CSCD 2016年第4期670-675,共6页
Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for th... Although some patients have successful peripheral nerve regeneration,a poor recovery of hand function often occurs after peripheral nerve injury.It is believed that the capability of brain plasticity is crucial for the recovery of hand function.The supplementary motor area may play a key role in brain remodeling after peripheral nerve injury.In this study,we explored the activation mode of the supplementary motor area during a motor imagery task.We investigated the plasticity of the central nervous system after brachial plexus injury,using the motor imagery task.Results from functional magnetic resonance imaging showed that after brachial plexus injury,the motor imagery task for the affected limbs of the patients triggered no obvious activation of bilateral supplementary motor areas.This result indicates that it is difficult to excite the supplementary motor areas of brachial plexus injury patients during a motor imagery task,thereby impacting brain remodeling.Deactivation of the supplementary motor area is likely to be a serious problem for brachial plexus injury patients in terms of preparing,initiating and executing certain movements,which may be partly responsible for the unsatisfactory clinical recovery of hand function. 展开更多
关键词 nerve regeneration peripheral nerve injury brachial plexus injury neuronal plasticity supplementary motor area premotor area magnetic resonance imaging motor preparation motor imagery clinical restoration of hand function cortical remodeling block design neural regeneration
下载PDF
上一页 1 下一页 到第
使用帮助 返回顶部