Based on the steady-state seepage method, we used the Mechanical Testing and Simulation 815.02 System and a self-designed seepage instrument for over-broken stone to measure seepage properties of water flows in three ...Based on the steady-state seepage method, we used the Mechanical Testing and Simulation 815.02 System and a self-designed seepage instrument for over-broken stone to measure seepage properties of water flows in three types of crushed rock samples. Three methods of confidence interval in describing permeability coefficients are presented: the secure interval, the calculated interval and the systemic interval. The lower bound of the secure interval can be applied to water-inrush and the upper bound can solve the problem of connectivity. For the calculated interval, as the axial pressure increases, the length of confidence interval is shortened and the upper and lower bounds are reduced. For the systemic interval, the length of its confidence interval, as well as the upper and lower bounds, clearly vary under low axial pressure but are fairly similar under high axial pressure. These three methods provide useful information and references for analyzing the permeability coefficient of over-broken rock.展开更多
A knowledge of soil permeability is essential to evaluate hydrologic characteristics of soil, such as water storage and water movement, and soil permeability coefficient is an important parameter that reflects soil pe...A knowledge of soil permeability is essential to evaluate hydrologic characteristics of soil, such as water storage and water movement, and soil permeability coefficient is an important parameter that reflects soil permeability. In order to confirm the acceptability of the one-dimensional horizontal infiltration method(one-D method) for simultaneously determining both the saturated and unsaturated permeability coefficients of loamy sand, we first measured the cumulative infiltration and the wetting front distance under various infiltration heads through a series of one-dimensional horizontal infiltration experiments, and then analyzed the relationships of the cumulative horizontal infiltration with the wetting front distance and the square root of infiltration time. We finally compared the permeability results from Gardner model based on the one-D method with the results from other two commonly-used methods(i.e., constant head method and van Genuchten model) to evaluate the acceptability and applicability of the one-D method. The results showed that there was a robust linear relationship between the cumulative horizontal infiltration and the wetting front distance, suggesting that it is more appropriate to take the soil moisture content after infiltration in the entire wetted zone as the average soil moisture content than as the saturated soil moisture content. The results also showed that there was a robust linear relationship between the cumulative horizontal infiltration and the square root of infiltration time, suggesting that the Philip infiltration formula can better reflect the characteristics of cumulative horizontal infiltration under different infiltration heads. The following two facts indicate that it is feasible to use the one-D method for simultaneously determining the saturated and unsaturated permeability coefficients of loamy sand. First, the saturated permeability coefficient(prescribed in the Gardner model) of loamy sand obtained from the one-D method well agreed with the value obtained from the constant head method. Second, the relationship of unsaturated permeability coefficient with soil water suction for loamy sand calculated using Gardner model based on the one-D method was nearly identical with the same relationship calculated using van Genuchten model.展开更多
The steel slag (SS) permeable concrete was prepared by SS. The influences of the aggregate-cement rate, the aggregate particle size, the water-cement rate, the admixture dosage and other factors on the permeability ...The steel slag (SS) permeable concrete was prepared by SS. The influences of the aggregate-cement rate, the aggregate particle size, the water-cement rate, the admixture dosage and other factors on the permeability coefficient of SS permeable concrete were analyzed. The law of influence was also investigated. The study serves as a technological reference for the construction and design of SS permeable concrete.展开更多
This study developed the equipment for thermo-fluid–solid coupling of methane-containing coal, and investigated the seepage character of loaded coal under different working conditions. Regarding the effective pressur...This study developed the equipment for thermo-fluid–solid coupling of methane-containing coal, and investigated the seepage character of loaded coal under different working conditions. Regarding the effective pressure as a variable, the variation characteristics of the gas permeability of loaded methane-containing coal has been studied under the conditions of different confining pressures and pore pressures. The qualitative and quantitative relationship between effective stress and permeability of loaded methane-containing coal has been established, considering the adsorption of deformation, amount of pore gas compression and temperature variation. The results show that the permeability of coal samples decreases along with the increasing effective stress. Based on the Darcy law, the correlation equation between the effective stress and permeability coefficient of coal seam has been established by combining the permeability coefficient of loaded coal and effective stress. On the basis of experimental data, this equation is used for calculation, and the results are in accordance with the measured gas permeability coefficient of coal seam. In conclusion, this method can be accurate and convenient to determine the gas permeability coefficient of coal seam, and provide evidence for forecasting that of the deep coal seam.展开更多
The factors influencing the permeability coefficient of gravelly soils used for the development of embankment dams(core wall)are analyzed.Such factors include(but are not limited to)soil size,anisotropy,density and bo...The factors influencing the permeability coefficient of gravelly soils used for the development of embankment dams(core wall)are analyzed.Such factors include(but are not limited to)soil size,anisotropy,density and boundary effects.A review of the literature is conducted and new directions of research are proposed.In such a framework,it is shown that gravelly soil with controlled density and vertical stress should be used to optimize the measurement of the vertical and horizontal permeability coefficients,respectively.展开更多
A study evaluating the relationship between porosity and permeability coefficient for pervious concrete (PC) is presented. In addition, the effect of mixture design parameters particularly, water-to-cement ratio (W/C)...A study evaluating the relationship between porosity and permeability coefficient for pervious concrete (PC) is presented. In addition, the effect of mixture design parameters particularly, water-to-cement ratio (W/C) and size of aggregate on the permeability coefficient of PC was investigated. The PC mixtures were made with 4 range of W/C and 2 range size of aggregate. PC mixes were made from each aggregate and were tested. The results showed that the W/C and aggregate size are key parameters which significantly affect the characteristic performance of PC. Permeability coefficient of coarse pervious concrete (CPC) is bigger than fine pervious concrete (FPC) and the porosity of CPC are bigger than porosity of FPC. A regression model (RM) along with analysis of variance (ANOVA) was conducted to study the significance of porosity distribution on permeability coefficient of PC. The statistical model developed in this study can facilitate prediction permeability coefficient of CPC and FPC as the sustainable pavements.展开更多
Compressive stress and tensile stress were applied to concrete specimens using test rigs designed by RILEM TC 246-TDC. Ultrasonic wave velocity and autoclam permeability system were used to characterize the damage var...Compressive stress and tensile stress were applied to concrete specimens using test rigs designed by RILEM TC 246-TDC. Ultrasonic wave velocity and autoclam permeability system were used to characterize the damage variable and gas permeability coefficient of concrete, respectively. The experimental results show that the strain value of concrete increases with the increasing of stress level and loading time. The damage variable and gas permeability coefficient of concrete under compressive stress decrease at first and increase after a threshold value between 0 and 0.6. When the concrete is under tensile load, the damage variable and gas permeability coefficient increase with tensile stress, with a significant increase from 0.3 to 0.6 tensile stress. There is a strong linear relationship between the damage variable and the gas permeability coefficient, suggesting both as good indicators to characterize the damage of concrete under stress.展开更多
Owing to the fact that the conventional deterministic back analysis of the permeability coefficient cannot reflect the uncertainties of parameters, including the hydraulic head at the boundary, the permeability coeffi...Owing to the fact that the conventional deterministic back analysis of the permeability coefficient cannot reflect the uncertainties of parameters, including the hydraulic head at the boundary, the permeability coefficient and measured hydraulic head, a stochastic back analysis taking consideration of uncertainties of parameters was performed using the generalized Bayesian method. Based on the stochastic finite element method (SFEM) for a seepage field, the variable metric algorithm and the generalized Bayesian method, formulas for stochastic back analysis of the permeability coefficient were derived. A case study of seepage analysis of a sluice foundation was performed to illustrate the proposed method. The results indicate that, with the generalized Bayesian method that considers the uncertainties of measured hydraulic head, the permeability coefficient and the hydraulic head at the boundary, both the mean and standard deviation of the permeability coefficient can be obtained and the standard deviation is less than that obtained by the conventional Bayesian method. Therefore, the present method is valid and applicable.展开更多
Transdermal drug delivery not only has contributed immensely to medical practice, but has enjoyed enormous interest in the field of cosmetic and pharmaceutical industries. Nevirapine, a non‐nucleoside reverse transcr...Transdermal drug delivery not only has contributed immensely to medical practice, but has enjoyed enormous interest in the field of cosmetic and pharmaceutical industries. Nevirapine, a non‐nucleoside reverse transcriptase inhibitor (NNRTI) is used clinically for the treatment of HIV‐ 1 infection. The aim of the present study is to investigate the influence of cosolvents (glycerol, propylene glycol, ethanol, polyethylene glycol 400) and surfactants (polysorbate 20, polysorbate 80, sodium lauryl sulfate, sodium cholate and cetrimide) on the dermal permeability coefficient of nevirapine by utilizing established and recognized mathematical model that employs partition coefficient as one of its molecular descriptors. The partition coefficient of nevirapine is determined in chloroform-water system at room temperature using the shake flask method. The results show that all the cosolvents used in this study decrease the partition coefficient of nevirapine. The same decrease in the partition coefficient of nevirapine is observed with all the surfactants investigated. The order of dermal enhancement potential of the vehicles studied based on the predicted permeability coefficient is glycerol > propylene glycol > ethanol > polyethylene glycol 400 for the cosolvents while tween 20 > tween 80 > sodium lauryl sulfate > sodium cholate > cetrimide for the surfactants. The maximum predicted flux through skin was obtained by multiplying the predicted permeability coefficient and the drug aqueous solubility. As the rate of penetration into the skin is quantitatively assessed by the use of permeability coefficient, the findings suggest that for dermal formulation of nevirapine, glycerol and tween 20 are the most preferred vehicles out of the vehicles investigated. Furthermore, the results of the correlation coefficients obtained by plotting permeability coefficient or maximum predicted flux, versus logarithm partition coefficient indicate that permeability coefficient can be a more reliable parameter to predict transdermal absorption of nevirapine than flux.展开更多
Fine-grained sediments are Quaternary sediments with grain sizes of not more than 2 mm.They startfirst when meeting water,their stability is related to the initial water volume triggering debrisflow,and thus plays an ...Fine-grained sediments are Quaternary sediments with grain sizes of not more than 2 mm.They startfirst when meeting water,their stability is related to the initial water volume triggering debrisflow,and thus plays an important role in debrisflow hazards early warning.The permeability coefficient is the inter-controlled factor offine-grained sediment stability.However,there is no hyperspectral model for detecting thefine-grained sediment permeability coefficient in large areas,which seriously affects the progress of debrisflow hazards early warning.Therefore,it is of great significance to establish a hyperspectral detection model for the permeability coefficient offine-grained sediments.Taking Beichuan County,Southwestern China as the case,a permeability coefficient hyperspectral detection model was established.The results show that eight bands are sensitive to the permeability coefficient with correlation coefficient(R)of 0.6343.T-test on the model shows that P-a values for sensitive bands are all less than 0.05,indicating the established model has a good prediction ability with a precision of 85.83%.These sensitive bands also indicate the spectral characteristics of the permeability coefficient.Therefore,it provides a scientific basis forfine-grained sediment stability detection in large areas and lays a theoretical foundation for debrisflow hazards’early warning.展开更多
In pumped storage projects,the permeability of rock masses is a crucial parameter in engineering design and construction.The rock mass permeability coefficient(K)is influenced by various geological parameters,and prev...In pumped storage projects,the permeability of rock masses is a crucial parameter in engineering design and construction.The rock mass permeability coefficient(K)is influenced by various geological parameters,and previous studies aimed to establish an accurate relationship between K and geological parameters.This study uses the improved sparrow search algorithm(ISSA)to optimize the parameter settings of the deep extreme learning machine(DELM),constructing a prediction model with flexible parameter selection and high accuracy.First,the Spearman method is applied to analyze the correlation between geological parameters.A sample database is built by comprehensively selecting four geological indexes:burial depth,rock quality designation(RQD),fracture density characteristic index(FD),and rock mass integrity designation(RID).Hence,the defects of the sparrow search algorithm(SSA)are enhanced using the improved strategy,and the initial input weights of the DELM are optimized.Finally,the proposed ISSA–DELM model is employed to predict the permeability coefficient of rock mass in the entire study area.The results showed that the predictive performance of the model is superior to that of the DELM and SSA–DELM.Therefore,this model successfully provides insights into the distribution characteristics of rock mass permeability at engineering sites.展开更多
The determination of inhomogeneous permeability coefficient was studied as a parameter-control inverse problem for parabolic-type equation in this paper. By virtue of PST, the solution of the inverse problem is conver...The determination of inhomogeneous permeability coefficient was studied as a parameter-control inverse problem for parabolic-type equation in this paper. By virtue of PST, the solution of the inverse problem is converted into an iteration procedure of solving a direct problem and solving a Fredholm integral equation of the first kind. Besides, Tikhonov normalization method is introduced to treat the uncertainty caused by the integral equation. Thus an algorithm for determining inhomogeneous permeability coefficient has been formulated and implemented. Numerical results show: (1) The algorithm presented in the paper is suitable to strongly inhomogeneous seepagel; (2) The additional information needed for solution is merely the seepage velocity on partical boundary, so that drill works can be reduced remarkably; (3) The algorithm is applicable to determining inhomogeneous transmission coefficients in groundwater engineering or other engineering.展开更多
This paper reports laboratory research carried out on natural and contaminated granitic residual soil from Covilha region (Portugal) to evaluate the coefficient of permeability in accordance with Darcy's law. The s...This paper reports laboratory research carried out on natural and contaminated granitic residual soil from Covilha region (Portugal) to evaluate the coefficient of permeability in accordance with Darcy's law. The soils are contaminated with hydrocarbon (Benzene Toluene Etilbenzene and Xilenes elements) and leached of urban solid waste. The specimens remained saturated and the consolidation and swelling are substantially completed at different effective confining pressures (25 to 400 kPa) before the measurements are performed at different hydraulic gradient to determine the effect of the void ratio, fabric and contamination of soil.展开更多
This research focused on the impact of mining on the permeability of key aquifuge (N2 laterite) that is widespread in the arid and semi-arid areas of northwestern China and is critical for preserving water resources...This research focused on the impact of mining on the permeability of key aquifuge (N2 laterite) that is widespread in the arid and semi-arid areas of northwestern China and is critical for preserving water resources. The impact of mining stress recovery on the permeability of cracked N2 laterite was assessed for parts of northwestern China that included the Jingle laterite and Baode laterite. The mineral compositions and swelling properties of the laterite at both locations were examined, and analytical results showed that the laterite contained abundant clay minerals. The Baode laterite exhibited higher expansibility than Jingle laterite. The triaxial creep permeability performance of laterite specimens with a prefabricated crack width of 1.0, 1.5, and 2.5 mm were tested. The results indicated that strain of cracked laterite all exhibited transient creep following each level of loading, and then unstable creep and stable creep. With the increase of loading, the transient creep deformation corresponding to each level of loading decreased, the unstable creep deformation produced by identical loading gradually and incrementally increased. The nonlinear power function equation was selected to fit creep grading curves which have high precision. The cracks within the laterite gradually closed with the stress recovery, and permeability gradually recovered. During the stress recovery, the narrower cracks exhibited a smaller change in permeability. However, for narrow cracks in mining soil, permeability recovered after mining stress when permeability was closer to initial permeability, and the Baode laterite showed greater recovery than that of the Jingle laterite.展开更多
A high sensitive method based on liquid chromatography tandem mass spectrometry(LC-MS/MS) was developed and validated for the study of permeability of danshensu(DS) and paeoniflorin(PF) in Caco-2 intestinal abso...A high sensitive method based on liquid chromatography tandem mass spectrometry(LC-MS/MS) was developed and validated for the study of permeability of danshensu(DS) and paeoniflorin(PF) in Caco-2 intestinal absorption model. The DS and PF were extracted from cell culture by vacuum-lyophilizing and then separated on a Zorbax Stable Bond C18 column with 0.1% acetic acid aqueous solution and methanol as mobile phase. Detection was carried out by negative electrospray ionization(ESI ) with selected reaction monitoring(SRM) mode. The apparent permeability coefficients(Papp) of DS and PF in Caco-2 cell medium were calculated and the effects of verapamil on the coefficients Papp of the two test compounds were also illustrated. The permeability of PF was much better than that of DS when the two compounds were administrated individually. Co-administration of DS and PF led to the decrease of the transport from apical side to basolateral side for both the compounds. However, the transport in the contrary direction were accelerated. It was also observed that verapamil could accelerate the transport of the test compounds from apical side to basolateral side. However, the absorption-enhanced effect of verapamil was attenuated when DS and PF were co-administrated. These observations suggest that both passive diffusion and active efflux involved in P-gp would effect the passage of DS and PF across Caco-2 cell monolayer. At the same time, the co-administration of DS and PF to an alteration of transport behavior, which suggests that the interaction must be taken into account when ‘n-in-one' samples were used in Caco-2 intestinal model.展开更多
Water permeability is an important property of nonwoven geotextiles used in drainage field, and usually it is obtained by testing individual layer or multi-layered nonwoven geotextiles. However, the permeability coeff...Water permeability is an important property of nonwoven geotextiles used in drainage field, and usually it is obtained by testing individual layer or multi-layered nonwoven geotextiles. However, the permeability coefficient tested by using different layers would be different for the same nonwoven geotextile. In this paper, the relation between them is studied based on Darcy's law. The study shows that vertical permeability coefficients are theoretically invariable no matter how many layers are tested; but experimental results show that vertical permeability coefficients decrease with the increase of nonwoven geotextile layers number.展开更多
During the operation of compressed air storage energy system,the rapid change of air pressure in a cavern will cause drastic changes in air density and permeability coefficient of sealing layer.To calculate and proper...During the operation of compressed air storage energy system,the rapid change of air pressure in a cavern will cause drastic changes in air density and permeability coefficient of sealing layer.To calculate and properly evaluate air tightness of polymer sealing caverns,the air-pressure-related air density and permeability must be considered.In this context,the high-pressure air penetration in the polymer sealing layer is studied in consideration of thermodynamic change of the cavern structure during the system operation.The air tightness model of compressed air storage energy caverns is then established.In the model,the permeability coefficient and air density of sealing layer vary with air pressure,and the effectiveness of the model is verified by field data in two test caverns.Finally,a compressed air storage energy cavern is taken as an example to understand the air tightness.The air leakage rate in the caverns is larger than that using air-pressure-independent permeability coefficient and air density,which is constant and small in the previous leakage rate calculation.Under the operating pressure of 4.5-10 MPa,the daily air leakage in the compressed air storage energy cavern of Yungang Mine with high polymer butyl rubber as the sealing material is 0.62%,which can meet the sealing requirements of compressed air storage energy caverns.The air tightness of the polymer sealing cavern is mainly affected by the cavern operating pressure,injected air temperature,cavern radius,and sealing layer thickness.The cavern air leakage rate will be decreased to reduce the cavern operating pressure the injection air temperature,or the cavern radius and sealing layer thickness will be increased.展开更多
The spewing of a screw conveyor easily occurs from the earth pressure balance(called EPB)shield in a water-rich sand stratum.This may lead to the collapse of the tunnel face and even serious subsidence of the ground s...The spewing of a screw conveyor easily occurs from the earth pressure balance(called EPB)shield in a water-rich sand stratum.This may lead to the collapse of the tunnel face and even serious subsidence of the ground surface.To understand the spewing mechanism of the shield screw conveyor and explore the critical hydraulic condition of soil spewing in a shield–soil chamber,a simplified theoretical model for the spewing of the screw conveyor was developed based on the equation of groundwater flow in the screw conveyor under turbulent state.Thus,coupling Darcy's law with Brinkman's equation,this model was implemented within the COMSOL Multiphysics framework.The underground water flow in the shield screw conveyor was simulated so as to obtain its velocity and flow rate.Numerical simulations show that the water pressure distribution is concentrated in the lower part of the soil chamber after the groundwater enters the soil chamber.When the groundwater enters the screw conveyor,its pressure gradually decreases along the direction of the screw conveyor.When the water flow reaches the stratum–shield interface,the flow velocity changes markedly:first increases and concentrates at the entrance of the lower soil chamber,plummets and stabilizes gradually,and increases again at the exit.The soil chamber and screw conveyor are significantly depressurized.It is also found that the soil permeability coefficient can be reduced to k<2.6×10^(−4)cm/s through appropriate soil improvement,which can effectively prevent the occurrence of spewing disasters.展开更多
To solve the cryogenic temperature problems faced by all-concrete liquefied natural gas(ACLNG)storage tanks during servicing,a low temperature resistant and high strength concrete(LHC)was designed from the perspective...To solve the cryogenic temperature problems faced by all-concrete liquefied natural gas(ACLNG)storage tanks during servicing,a low temperature resistant and high strength concrete(LHC)was designed from the perspectives of reducing water-binder ratio,removing coarse aggregates,optimizing composite mineral admixture and utilizing steel fibers.The variation laws of compressive and tensile strength,elastic modulus and Poisson’s ratio for C60 concrete and LHC were compared and analyzed under the temperatures from 10 to-165℃through uniaxial compression and tensile tests.The rapid freezing method was adopted to analyze the evolution process of mass and relative dynamic elastic modulus loss rates for C60 and LHC in 0-300 freeze-thaw cycles.The gas permeability test was carried out,and the laws of gas permeability coefficient varied with temperature and cryogenic freeze-thaw cycles were obtained.Then,the grey dynamic model GM(1,1)was used to predict the variation laws of physical and mechanical parameters on the basis of the test data.The test results demonstrate that the compressive strength,elastic modulus and Poisson’s ratio for both C60 and LHC increase significantly from 10 to-165℃,but the specific variation laws are difierent,and there is a phenomenon that some parameters decrease after reaching a critical temperature range for C60.The uniaxial tensile strength increases first and then decreases as temperature decreases,and finally increases slightly at-165℃for both C60 and LHC.The mass and relative dynamic elastic modulus loss rates of LHC are much lower than that of C60 under different freeze-thaw cycles.The gas permeability coefficient of C60 declines gradually with the drop of temperature,and increases gradually with the number of freeze-thaw cycles while the gas permeability coefficient of LHC basically remains stable and is much lower than that of C60.Therefore,such a conclusion can be drawn that LHC has better properties at cryogenic temperature.On the premise of providing consistent functional mode,GM(1,1)can predict the test data with high accuracy,which well reflects the variation laws of relevant parameters.展开更多
High-strength pervious concrete(HSPC) with porosity ranging from 0.08% to 2.011% was prepared. The mechanical properties and rainstorm waterlogging resistance of HSPC were evaluated,and a design method of HSPC pore ch...High-strength pervious concrete(HSPC) with porosity ranging from 0.08% to 2.011% was prepared. The mechanical properties and rainstorm waterlogging resistance of HSPC were evaluated,and a design method of HSPC pore characteristics(porosity and pore diameter) based on the mechanical properties and rainstorm waterlogging resistance was proposed. The results showed that the reduction of effective cross-sectional area caused by artificial channels was the main factor affecting flexural strength but had limited influence on compressive strength. Compared with the concrete matrix without artificial channels,the compressive strength of HSPC with porosity of 2.011% decreased by 7.4%, while the flexural strength decreased by 48.3%. The permeability coefficient of HSPC can reach 16.35 mm/s even at low porosity(2.011%).HSPC can meet the requirements of no rainstorm waterlogging, even if exposed to 100-year rainstorms. When the mechanical properties and rainstorm waterlogging resistance are compromised, the recommended porosity ranges from 1.1% to 3.5%, and the recommended pore diameter ranges from 0.8 to 2.7 mm.展开更多
基金Financial support for this work, provided by the National Natural Science Foundation of China (Nos. 50774083 and 41074040)the Program for New Century Excellent Talents in University (No. NCET-07-0803)the National Key Basic Research Program (No. 2009CB219605)
文摘Based on the steady-state seepage method, we used the Mechanical Testing and Simulation 815.02 System and a self-designed seepage instrument for over-broken stone to measure seepage properties of water flows in three types of crushed rock samples. Three methods of confidence interval in describing permeability coefficients are presented: the secure interval, the calculated interval and the systemic interval. The lower bound of the secure interval can be applied to water-inrush and the upper bound can solve the problem of connectivity. For the calculated interval, as the axial pressure increases, the length of confidence interval is shortened and the upper and lower bounds are reduced. For the systemic interval, the length of its confidence interval, as well as the upper and lower bounds, clearly vary under low axial pressure but are fairly similar under high axial pressure. These three methods provide useful information and references for analyzing the permeability coefficient of over-broken rock.
基金funded by the National Basic Research Program of China (2013CB429902)the National Natural Science Foundation of China (U1303181, 41671032)
文摘A knowledge of soil permeability is essential to evaluate hydrologic characteristics of soil, such as water storage and water movement, and soil permeability coefficient is an important parameter that reflects soil permeability. In order to confirm the acceptability of the one-dimensional horizontal infiltration method(one-D method) for simultaneously determining both the saturated and unsaturated permeability coefficients of loamy sand, we first measured the cumulative infiltration and the wetting front distance under various infiltration heads through a series of one-dimensional horizontal infiltration experiments, and then analyzed the relationships of the cumulative horizontal infiltration with the wetting front distance and the square root of infiltration time. We finally compared the permeability results from Gardner model based on the one-D method with the results from other two commonly-used methods(i.e., constant head method and van Genuchten model) to evaluate the acceptability and applicability of the one-D method. The results showed that there was a robust linear relationship between the cumulative horizontal infiltration and the wetting front distance, suggesting that it is more appropriate to take the soil moisture content after infiltration in the entire wetted zone as the average soil moisture content than as the saturated soil moisture content. The results also showed that there was a robust linear relationship between the cumulative horizontal infiltration and the square root of infiltration time, suggesting that the Philip infiltration formula can better reflect the characteristics of cumulative horizontal infiltration under different infiltration heads. The following two facts indicate that it is feasible to use the one-D method for simultaneously determining the saturated and unsaturated permeability coefficients of loamy sand. First, the saturated permeability coefficient(prescribed in the Gardner model) of loamy sand obtained from the one-D method well agreed with the value obtained from the constant head method. Second, the relationship of unsaturated permeability coefficient with soil water suction for loamy sand calculated using Gardner model based on the one-D method was nearly identical with the same relationship calculated using van Genuchten model.
文摘The steel slag (SS) permeable concrete was prepared by SS. The influences of the aggregate-cement rate, the aggregate particle size, the water-cement rate, the admixture dosage and other factors on the permeability coefficient of SS permeable concrete were analyzed. The law of influence was also investigated. The study serves as a technological reference for the construction and design of SS permeable concrete.
基金supported by the National Basic Research Program of China (No. 2012CB723103)the Ministry of Education Innovation Team of China (No. IRT1235)+2 种基金the State Key Laboratory Cultivation Base for Gas Geology and Gas Control of Henan Polytechnic University of China (No. WS2012A01)the Provincial Open Laboratory Fund of Minal Materials Key disciplines of China (No. MEM13-10)China Postdoctoral Science Foundation (No. 2014M552003)
文摘This study developed the equipment for thermo-fluid–solid coupling of methane-containing coal, and investigated the seepage character of loaded coal under different working conditions. Regarding the effective pressure as a variable, the variation characteristics of the gas permeability of loaded methane-containing coal has been studied under the conditions of different confining pressures and pore pressures. The qualitative and quantitative relationship between effective stress and permeability of loaded methane-containing coal has been established, considering the adsorption of deformation, amount of pore gas compression and temperature variation. The results show that the permeability of coal samples decreases along with the increasing effective stress. Based on the Darcy law, the correlation equation between the effective stress and permeability coefficient of coal seam has been established by combining the permeability coefficient of loaded coal and effective stress. On the basis of experimental data, this equation is used for calculation, and the results are in accordance with the measured gas permeability coefficient of coal seam. In conclusion, this method can be accurate and convenient to determine the gas permeability coefficient of coal seam, and provide evidence for forecasting that of the deep coal seam.
基金The work is supported by National Key Research and Development Program of China(No.2017YFC0404803)Guizhou High-Level Innovative Talents Project[2018](No.5630)+2 种基金Guizhou Science and Support[2019](No.2869)State Key Laboratory of Simulation and Regulation of Water Cycle in River Basin(No.SKL2020ZY09)Science and Technology Project of Huaneng Group Headquarters(HNKJ17-H18).
文摘The factors influencing the permeability coefficient of gravelly soils used for the development of embankment dams(core wall)are analyzed.Such factors include(but are not limited to)soil size,anisotropy,density and boundary effects.A review of the literature is conducted and new directions of research are proposed.In such a framework,it is shown that gravelly soil with controlled density and vertical stress should be used to optimize the measurement of the vertical and horizontal permeability coefficients,respectively.
文摘A study evaluating the relationship between porosity and permeability coefficient for pervious concrete (PC) is presented. In addition, the effect of mixture design parameters particularly, water-to-cement ratio (W/C) and size of aggregate on the permeability coefficient of PC was investigated. The PC mixtures were made with 4 range of W/C and 2 range size of aggregate. PC mixes were made from each aggregate and were tested. The results showed that the W/C and aggregate size are key parameters which significantly affect the characteristic performance of PC. Permeability coefficient of coarse pervious concrete (CPC) is bigger than fine pervious concrete (FPC) and the porosity of CPC are bigger than porosity of FPC. A regression model (RM) along with analysis of variance (ANOVA) was conducted to study the significance of porosity distribution on permeability coefficient of PC. The statistical model developed in this study can facilitate prediction permeability coefficient of CPC and FPC as the sustainable pavements.
基金Funded by the National Natural Science Foundation of China(No.51320105016)
文摘Compressive stress and tensile stress were applied to concrete specimens using test rigs designed by RILEM TC 246-TDC. Ultrasonic wave velocity and autoclam permeability system were used to characterize the damage variable and gas permeability coefficient of concrete, respectively. The experimental results show that the strain value of concrete increases with the increasing of stress level and loading time. The damage variable and gas permeability coefficient of concrete under compressive stress decrease at first and increase after a threshold value between 0 and 0.6. When the concrete is under tensile load, the damage variable and gas permeability coefficient increase with tensile stress, with a significant increase from 0.3 to 0.6 tensile stress. There is a strong linear relationship between the damage variable and the gas permeability coefficient, suggesting both as good indicators to characterize the damage of concrete under stress.
基金supported by the National Natural Science Foundation of China (Grant No. 50579090)the National Basic Research Program of China (973 Program, Grant No. 2007CB714102)National Science and Technology Support Program of China (Program for the Eleventh Five-Year Plan, Grant No. 2006BAB04A06)
文摘Owing to the fact that the conventional deterministic back analysis of the permeability coefficient cannot reflect the uncertainties of parameters, including the hydraulic head at the boundary, the permeability coefficient and measured hydraulic head, a stochastic back analysis taking consideration of uncertainties of parameters was performed using the generalized Bayesian method. Based on the stochastic finite element method (SFEM) for a seepage field, the variable metric algorithm and the generalized Bayesian method, formulas for stochastic back analysis of the permeability coefficient were derived. A case study of seepage analysis of a sluice foundation was performed to illustrate the proposed method. The results indicate that, with the generalized Bayesian method that considers the uncertainties of measured hydraulic head, the permeability coefficient and the hydraulic head at the boundary, both the mean and standard deviation of the permeability coefficient can be obtained and the standard deviation is less than that obtained by the conventional Bayesian method. Therefore, the present method is valid and applicable.
文摘Transdermal drug delivery not only has contributed immensely to medical practice, but has enjoyed enormous interest in the field of cosmetic and pharmaceutical industries. Nevirapine, a non‐nucleoside reverse transcriptase inhibitor (NNRTI) is used clinically for the treatment of HIV‐ 1 infection. The aim of the present study is to investigate the influence of cosolvents (glycerol, propylene glycol, ethanol, polyethylene glycol 400) and surfactants (polysorbate 20, polysorbate 80, sodium lauryl sulfate, sodium cholate and cetrimide) on the dermal permeability coefficient of nevirapine by utilizing established and recognized mathematical model that employs partition coefficient as one of its molecular descriptors. The partition coefficient of nevirapine is determined in chloroform-water system at room temperature using the shake flask method. The results show that all the cosolvents used in this study decrease the partition coefficient of nevirapine. The same decrease in the partition coefficient of nevirapine is observed with all the surfactants investigated. The order of dermal enhancement potential of the vehicles studied based on the predicted permeability coefficient is glycerol > propylene glycol > ethanol > polyethylene glycol 400 for the cosolvents while tween 20 > tween 80 > sodium lauryl sulfate > sodium cholate > cetrimide for the surfactants. The maximum predicted flux through skin was obtained by multiplying the predicted permeability coefficient and the drug aqueous solubility. As the rate of penetration into the skin is quantitatively assessed by the use of permeability coefficient, the findings suggest that for dermal formulation of nevirapine, glycerol and tween 20 are the most preferred vehicles out of the vehicles investigated. Furthermore, the results of the correlation coefficients obtained by plotting permeability coefficient or maximum predicted flux, versus logarithm partition coefficient indicate that permeability coefficient can be a more reliable parameter to predict transdermal absorption of nevirapine than flux.
基金funded in part by the Innovative Research Program of the International Research Center of Big Data for Sustainable Development Goals[grant number CBAS2022IRP03]the National Natural Science Foundation of China[grant number 42071312]the Hainan Hundred Special Project[grant number 31,JTT[2018]].
文摘Fine-grained sediments are Quaternary sediments with grain sizes of not more than 2 mm.They startfirst when meeting water,their stability is related to the initial water volume triggering debrisflow,and thus plays an important role in debrisflow hazards early warning.The permeability coefficient is the inter-controlled factor offine-grained sediment stability.However,there is no hyperspectral model for detecting thefine-grained sediment permeability coefficient in large areas,which seriously affects the progress of debrisflow hazards early warning.Therefore,it is of great significance to establish a hyperspectral detection model for the permeability coefficient offine-grained sediments.Taking Beichuan County,Southwestern China as the case,a permeability coefficient hyperspectral detection model was established.The results show that eight bands are sensitive to the permeability coefficient with correlation coefficient(R)of 0.6343.T-test on the model shows that P-a values for sensitive bands are all less than 0.05,indicating the established model has a good prediction ability with a precision of 85.83%.These sensitive bands also indicate the spectral characteristics of the permeability coefficient.Therefore,it provides a scientific basis forfine-grained sediment stability detection in large areas and lays a theoretical foundation for debrisflow hazards’early warning.
文摘In pumped storage projects,the permeability of rock masses is a crucial parameter in engineering design and construction.The rock mass permeability coefficient(K)is influenced by various geological parameters,and previous studies aimed to establish an accurate relationship between K and geological parameters.This study uses the improved sparrow search algorithm(ISSA)to optimize the parameter settings of the deep extreme learning machine(DELM),constructing a prediction model with flexible parameter selection and high accuracy.First,the Spearman method is applied to analyze the correlation between geological parameters.A sample database is built by comprehensively selecting four geological indexes:burial depth,rock quality designation(RQD),fracture density characteristic index(FD),and rock mass integrity designation(RID).Hence,the defects of the sparrow search algorithm(SSA)are enhanced using the improved strategy,and the initial input weights of the DELM are optimized.Finally,the proposed ISSA–DELM model is employed to predict the permeability coefficient of rock mass in the entire study area.The results showed that the predictive performance of the model is superior to that of the DELM and SSA–DELM.Therefore,this model successfully provides insights into the distribution characteristics of rock mass permeability at engineering sites.
文摘The determination of inhomogeneous permeability coefficient was studied as a parameter-control inverse problem for parabolic-type equation in this paper. By virtue of PST, the solution of the inverse problem is converted into an iteration procedure of solving a direct problem and solving a Fredholm integral equation of the first kind. Besides, Tikhonov normalization method is introduced to treat the uncertainty caused by the integral equation. Thus an algorithm for determining inhomogeneous permeability coefficient has been formulated and implemented. Numerical results show: (1) The algorithm presented in the paper is suitable to strongly inhomogeneous seepagel; (2) The additional information needed for solution is merely the seepage velocity on partical boundary, so that drill works can be reduced remarkably; (3) The algorithm is applicable to determining inhomogeneous transmission coefficients in groundwater engineering or other engineering.
文摘This paper reports laboratory research carried out on natural and contaminated granitic residual soil from Covilha region (Portugal) to evaluate the coefficient of permeability in accordance with Darcy's law. The soils are contaminated with hydrocarbon (Benzene Toluene Etilbenzene and Xilenes elements) and leached of urban solid waste. The specimens remained saturated and the consolidation and swelling are substantially completed at different effective confining pressures (25 to 400 kPa) before the measurements are performed at different hydraulic gradient to determine the effect of the void ratio, fabric and contamination of soil.
基金The study was jointly supported by the State Key Program of National Natural Science Foundation of China (Grant No. 41430643) and the National Key Basic Research Program of China (973 Program) (Grant No. 2015CB251601).
文摘This research focused on the impact of mining on the permeability of key aquifuge (N2 laterite) that is widespread in the arid and semi-arid areas of northwestern China and is critical for preserving water resources. The impact of mining stress recovery on the permeability of cracked N2 laterite was assessed for parts of northwestern China that included the Jingle laterite and Baode laterite. The mineral compositions and swelling properties of the laterite at both locations were examined, and analytical results showed that the laterite contained abundant clay minerals. The Baode laterite exhibited higher expansibility than Jingle laterite. The triaxial creep permeability performance of laterite specimens with a prefabricated crack width of 1.0, 1.5, and 2.5 mm were tested. The results indicated that strain of cracked laterite all exhibited transient creep following each level of loading, and then unstable creep and stable creep. With the increase of loading, the transient creep deformation corresponding to each level of loading decreased, the unstable creep deformation produced by identical loading gradually and incrementally increased. The nonlinear power function equation was selected to fit creep grading curves which have high precision. The cracks within the laterite gradually closed with the stress recovery, and permeability gradually recovered. During the stress recovery, the narrower cracks exhibited a smaller change in permeability. However, for narrow cracks in mining soil, permeability recovered after mining stress when permeability was closer to initial permeability, and the Baode laterite showed greater recovery than that of the Jingle laterite.
基金the National Basic Research Priorities Program of China(No. 2005CB523402)the Natural Science Foundation of Zhejiang Province,China(No.Y204418)the Program for New Century Excellent Talents in University of China (No.NCET-06-0515)
文摘A high sensitive method based on liquid chromatography tandem mass spectrometry(LC-MS/MS) was developed and validated for the study of permeability of danshensu(DS) and paeoniflorin(PF) in Caco-2 intestinal absorption model. The DS and PF were extracted from cell culture by vacuum-lyophilizing and then separated on a Zorbax Stable Bond C18 column with 0.1% acetic acid aqueous solution and methanol as mobile phase. Detection was carried out by negative electrospray ionization(ESI ) with selected reaction monitoring(SRM) mode. The apparent permeability coefficients(Papp) of DS and PF in Caco-2 cell medium were calculated and the effects of verapamil on the coefficients Papp of the two test compounds were also illustrated. The permeability of PF was much better than that of DS when the two compounds were administrated individually. Co-administration of DS and PF led to the decrease of the transport from apical side to basolateral side for both the compounds. However, the transport in the contrary direction were accelerated. It was also observed that verapamil could accelerate the transport of the test compounds from apical side to basolateral side. However, the absorption-enhanced effect of verapamil was attenuated when DS and PF were co-administrated. These observations suggest that both passive diffusion and active efflux involved in P-gp would effect the passage of DS and PF across Caco-2 cell monolayer. At the same time, the co-administration of DS and PF to an alteration of transport behavior, which suggests that the interaction must be taken into account when ‘n-in-one' samples were used in Caco-2 intestinal model.
文摘Water permeability is an important property of nonwoven geotextiles used in drainage field, and usually it is obtained by testing individual layer or multi-layered nonwoven geotextiles. However, the permeability coefficient tested by using different layers would be different for the same nonwoven geotextile. In this paper, the relation between them is studied based on Darcy's law. The study shows that vertical permeability coefficients are theoretically invariable no matter how many layers are tested; but experimental results show that vertical permeability coefficients decrease with the increase of nonwoven geotextile layers number.
基金We acknowledge the funding support from the National Science Foundation of China(Grant No.52278402)the Young Scientist Project of the National Key Research and Development Program of China(Grant No.2021YFC2900600)the Fundamental Research Funds for the Central Universities of China(Grant No.22120220117).
文摘During the operation of compressed air storage energy system,the rapid change of air pressure in a cavern will cause drastic changes in air density and permeability coefficient of sealing layer.To calculate and properly evaluate air tightness of polymer sealing caverns,the air-pressure-related air density and permeability must be considered.In this context,the high-pressure air penetration in the polymer sealing layer is studied in consideration of thermodynamic change of the cavern structure during the system operation.The air tightness model of compressed air storage energy caverns is then established.In the model,the permeability coefficient and air density of sealing layer vary with air pressure,and the effectiveness of the model is verified by field data in two test caverns.Finally,a compressed air storage energy cavern is taken as an example to understand the air tightness.The air leakage rate in the caverns is larger than that using air-pressure-independent permeability coefficient and air density,which is constant and small in the previous leakage rate calculation.Under the operating pressure of 4.5-10 MPa,the daily air leakage in the compressed air storage energy cavern of Yungang Mine with high polymer butyl rubber as the sealing material is 0.62%,which can meet the sealing requirements of compressed air storage energy caverns.The air tightness of the polymer sealing cavern is mainly affected by the cavern operating pressure,injected air temperature,cavern radius,and sealing layer thickness.The cavern air leakage rate will be decreased to reduce the cavern operating pressure the injection air temperature,or the cavern radius and sealing layer thickness will be increased.
基金National Natural Science Foundation of China,Grant/Award Number:U1261212。
文摘The spewing of a screw conveyor easily occurs from the earth pressure balance(called EPB)shield in a water-rich sand stratum.This may lead to the collapse of the tunnel face and even serious subsidence of the ground surface.To understand the spewing mechanism of the shield screw conveyor and explore the critical hydraulic condition of soil spewing in a shield–soil chamber,a simplified theoretical model for the spewing of the screw conveyor was developed based on the equation of groundwater flow in the screw conveyor under turbulent state.Thus,coupling Darcy's law with Brinkman's equation,this model was implemented within the COMSOL Multiphysics framework.The underground water flow in the shield screw conveyor was simulated so as to obtain its velocity and flow rate.Numerical simulations show that the water pressure distribution is concentrated in the lower part of the soil chamber after the groundwater enters the soil chamber.When the groundwater enters the screw conveyor,its pressure gradually decreases along the direction of the screw conveyor.When the water flow reaches the stratum–shield interface,the flow velocity changes markedly:first increases and concentrates at the entrance of the lower soil chamber,plummets and stabilizes gradually,and increases again at the exit.The soil chamber and screw conveyor are significantly depressurized.It is also found that the soil permeability coefficient can be reduced to k<2.6×10^(−4)cm/s through appropriate soil improvement,which can effectively prevent the occurrence of spewing disasters.
基金National Key Research and Development Projects of China(No.2022YFB2602605)。
文摘To solve the cryogenic temperature problems faced by all-concrete liquefied natural gas(ACLNG)storage tanks during servicing,a low temperature resistant and high strength concrete(LHC)was designed from the perspectives of reducing water-binder ratio,removing coarse aggregates,optimizing composite mineral admixture and utilizing steel fibers.The variation laws of compressive and tensile strength,elastic modulus and Poisson’s ratio for C60 concrete and LHC were compared and analyzed under the temperatures from 10 to-165℃through uniaxial compression and tensile tests.The rapid freezing method was adopted to analyze the evolution process of mass and relative dynamic elastic modulus loss rates for C60 and LHC in 0-300 freeze-thaw cycles.The gas permeability test was carried out,and the laws of gas permeability coefficient varied with temperature and cryogenic freeze-thaw cycles were obtained.Then,the grey dynamic model GM(1,1)was used to predict the variation laws of physical and mechanical parameters on the basis of the test data.The test results demonstrate that the compressive strength,elastic modulus and Poisson’s ratio for both C60 and LHC increase significantly from 10 to-165℃,but the specific variation laws are difierent,and there is a phenomenon that some parameters decrease after reaching a critical temperature range for C60.The uniaxial tensile strength increases first and then decreases as temperature decreases,and finally increases slightly at-165℃for both C60 and LHC.The mass and relative dynamic elastic modulus loss rates of LHC are much lower than that of C60 under different freeze-thaw cycles.The gas permeability coefficient of C60 declines gradually with the drop of temperature,and increases gradually with the number of freeze-thaw cycles while the gas permeability coefficient of LHC basically remains stable and is much lower than that of C60.Therefore,such a conclusion can be drawn that LHC has better properties at cryogenic temperature.On the premise of providing consistent functional mode,GM(1,1)can predict the test data with high accuracy,which well reflects the variation laws of relevant parameters.
基金Funded by the National Natural Science Foundation of China (No. 51878081)Natural Science Foundation of Jiangsu Province (No. BK20220626)+1 种基金Changzhou Leading Innovative Talent Introduction and Cultivation Project (No. CQ20210085)Postgraduate Research and Practice Innovation Program of Jiangsu Province (No. KYCX21_2847)。
文摘High-strength pervious concrete(HSPC) with porosity ranging from 0.08% to 2.011% was prepared. The mechanical properties and rainstorm waterlogging resistance of HSPC were evaluated,and a design method of HSPC pore characteristics(porosity and pore diameter) based on the mechanical properties and rainstorm waterlogging resistance was proposed. The results showed that the reduction of effective cross-sectional area caused by artificial channels was the main factor affecting flexural strength but had limited influence on compressive strength. Compared with the concrete matrix without artificial channels,the compressive strength of HSPC with porosity of 2.011% decreased by 7.4%, while the flexural strength decreased by 48.3%. The permeability coefficient of HSPC can reach 16.35 mm/s even at low porosity(2.011%).HSPC can meet the requirements of no rainstorm waterlogging, even if exposed to 100-year rainstorms. When the mechanical properties and rainstorm waterlogging resistance are compromised, the recommended porosity ranges from 1.1% to 3.5%, and the recommended pore diameter ranges from 0.8 to 2.7 mm.