The phase relation of harmonics in high-intensity focused ultrasound is investigated numerically and experimen- tally. The nonlinear Westervelt equation is solved to model nonlinear focused sound field by using the fi...The phase relation of harmonics in high-intensity focused ultrasound is investigated numerically and experimen- tally. The nonlinear Westervelt equation is solved to model nonlinear focused sound field by using the finite difference time domain method. Experimental waveforms are measured by a robust needle hydrophone. Then the relative phase quantity is introduced and obtained by using the zero-phase filter. The results show that the nth harmonic relative phase quantity is approximately (n - 1) π/3 at geometric center and increases along the axial direction. Moreover, the relative phase quantity decreases with the increase of source amplitude. This phase relation gives an explanation of some nonlinear phenomena such as the discrepancy of positive and negative pressure.展开更多
We realize broadband acoustic focusing effect by employing two symmetric Airy beams generated from phased arrays,in which the units of the phased arrays consist of different numbers of cavity structures, each of which...We realize broadband acoustic focusing effect by employing two symmetric Airy beams generated from phased arrays,in which the units of the phased arrays consist of different numbers of cavity structures, each of which is composed of a square cavity and two inclined channels in air. The exotic phenomenon arises from the energy overlapping of the two symmetric Airy beams. Besides, we demonstrate the focusing performance with high self-healing property, and discuss the effects of structure parameters on focusing performance, and present the characteristics of the cavity structure with straight channels. Compared with other acoustic lenses, the proposed acoustic lens has advantages of broad bandwidth(about 1.4 kHz), high self-healing property of focusing performance, and free adjustment of focal length. Our finding should have great potential applications in ultrasound imaging and medical diagnosis.展开更多
A liquid-phase isoelectric focusing electrophoresis system(Rotofor) was used as the prefractionation tool for the sample preparation in the MALDI-MS analysis of a protein mixture. Each fraction collected was then dire...A liquid-phase isoelectric focusing electrophoresis system(Rotofor) was used as the prefractionation tool for the sample preparation in the MALDI-MS analysis of a protein mixture. Each fraction collected was then directly subjected to MALDI-TOF-MS analysis. By this approach, we are able to resolve two types of hemoglobins, A and C, which cannot be successfully separated by means of the traditional SDS-PAGE method.展开更多
We propose a new approach for generating a multiple focal spot segment of subwavelength size, by tight focusing of a phase modulated radially polarized Laguerre Bessel Gaussian beam. The focusing properties are invest...We propose a new approach for generating a multiple focal spot segment of subwavelength size, by tight focusing of a phase modulated radially polarized Laguerre Bessel Gaussian beam. The focusing properties are investigated theoretically by .vector diffraction theory. We observe that the focal segment with multiple focal structures is separated with different axial distances and a super long dark channel can be generated by properly tuning the phase of the incident radially polarized Laguerre Bessel Gaussian beam. We presume that such multiple focal patterns and high intense beam may find applications in atom optics, optical manipulations and multiple optical trapping.展开更多
We report the realization of broadband reflected acoustic focusing lenses based on thermoacoustic phased arrays of Bessel-like beams, in which the units of phase manipulation are composed of three rigid insulated boun...We report the realization of broadband reflected acoustic focusing lenses based on thermoacoustic phased arrays of Bessel-like beams, in which the units of phase manipulation are composed of three rigid insulated boundaries and a thermal insulation film in air with different temperatures. Based on these units, we realize a reflected focusing lens which can focus reflected acoustic energy on a line, and its fractional bandwidth can reach about 0.29. In addition, we discuss the influences of the base angle of Bessel-like beam, the number of basic unit, and the variation of unit temperature on focusing performances in details. Furthermore, the reflected focusing lens for the cylindrical acoustic wave based on the Bessel-like beam is also demonstrated. The proposed focusing lens has the advantages of a broad working bandwidth, large focus size,and high robustness, which may provide possibilities for the design and application of acoustic lenses.展开更多
We investigate the beam focusing technology of shear-vertical(SV) waves for a contact-type linear phased array to overcome the shortcomings of conventional wedge transducer arrays. The numerical simulation reveals the...We investigate the beam focusing technology of shear-vertical(SV) waves for a contact-type linear phased array to overcome the shortcomings of conventional wedge transducer arrays. The numerical simulation reveals the transient excitation and propagation characteristics of SV waves. It is found that the element size plays an important role in determining the transient radiation directivity of SV waves. The transient beam focusing characteristics of SV waves for various array parameters are deeply studied. It is particularly interesting to see that smaller element width will provide the focused beam of SV waves with higher quality, while larger element width may result in erratic fluctuation of focusing energy around the focal point. There exists a specific range of inter-element spacing for optimum focusing performance. Moreover, good beam focusing performance of SV waves can be achieved only at high steering angles.展开更多
Based on phase focusing theory, focusing waves with different spectral types and breaking severities were generated in a wave flume. The time series of surface elevation fluctuation along the flume were obtained by ut...Based on phase focusing theory, focusing waves with different spectral types and breaking severities were generated in a wave flume. The time series of surface elevation fluctuation along the flume were obtained by utilizing 22 wave probes mounted along the mid-stream of the flume. Based on the wave spectrum obtained using fast Fourier transform(FFT), the instability characteristics of the energy spectrum were reported in this paper. By analyzing the variation of total spectral energy, the total spectral energy after wave breaking was found to clearly decrease, and the loss value and ratio gradually increased and tended to stabilize with the enhancement of breaking severity for different spectral types. When wave breaking occurred, the energy loss was primarily in a high-frequency range of f/fp>1.0, and energy gain was primarily in a low-frequency range of f/fp<1.0. As the breaking severity increased, the energy gain-loss ratio decreased gradually, which demonstrates that the energy was mostly dissipated. For plunging waves, the energy gain-loss ratio reached 24% for the constant wave steepness(CWS) spectrum, and was slightly larger at approximately 30% for the constant wave amplitude(CWA) spectrum, and was the largest at approximately 42% for the Pierson-Moskowitz(PM) spectrum.展开更多
This article theoretically studies the influence of inhomogeneous abdominal walls on focused therapeutic ultrasound based on the phase screen model. An inhomogeneous tissue is considered as a combination of a homogene...This article theoretically studies the influence of inhomogeneous abdominal walls on focused therapeutic ultrasound based on the phase screen model. An inhomogeneous tissue is considered as a combination of a homogeneous medium and a phase aberration screen. Variations of acoustic parameters such as peak positive pressure, peak negative pressure, and acoustic intensity are discussed with respect to the phase screen statistics of human abdominal walls. Results indicate that the abdominal wall can result in energy loss of the sound in the focal plane. For a typical human abdominal wall with correlation length of 7.9 mm and variance of 0.36, the peak acoustic intensity radiated from a 1MHz transmitter with a radius of 30 mm can be reduced by about 14% at the focal plane.展开更多
Four focusing models for generation of freak waves are presented. An extreme wave focusing model is presented on the basis of the enhanced High-Order Spectral (HOS) method and the importance of the nonlinear wave-wa...Four focusing models for generation of freak waves are presented. An extreme wave focusing model is presented on the basis of the enhanced High-Order Spectral (HOS) method and the importance of the nonlinear wave-wave interaction is evaluated by comparison of the calculated results with experimental and theoretical data. Based on the modification of the Longuet-Higgins model, four wave models for generation of freak waves (a. extreme wave model + random wave model; b. extreme wave model + regular wave model; e. phase interval modulation wave focusing model; d. number modulation wave focusing model with the same phase) are proposed. By use of different energy distribution techniques in the four models, freak wave events are obtained with different Hmax/Hs in finite space and time.展开更多
Based on the Longuet-Higgins wave model theory, the previews studies have shown that freak waves can be generated in finite space and time successfully. However, as to generating high nonlinear freak waves, the simula...Based on the Longuet-Higgins wave model theory, the previews studies have shown that freak waves can be generated in finite space and time successfully. However, as to generating high nonlinear freak waves, the simulation results will be unrealistic. Therefore, a modified phase modulation method for simulating high nonlinear freak waves was developed. The surface elevations of some wave components at certain time and place are positive by modulating the corresponding random initial phases, then the total surface elevation at the focused point is enhanced and furthermore a freak wave event is generated. The new method can not only make the freak wave occur at certain time and place, but also make the simulated wave surface time series satisfy statistical properties of the realistic sea state and keep identical with the target wave spectrum. This numerical approach is of good precision and high efficiency by the comparisons of the simulated freak waves and the recorded freak waves.展开更多
We design an asymmetric transmission system(ATS)with two flat acoustic metasurfaces(AMs)to yield bidirectional asymmetric acoustic focusing(BAAF).The acoustic waves could be focused on both sides of the ATS with diffe...We design an asymmetric transmission system(ATS)with two flat acoustic metasurfaces(AMs)to yield bidirectional asymmetric acoustic focusing(BAAF).The acoustic waves could be focused on both sides of the ATS with different focal lengths and intensities.To achieve high intensity energy concentration,the accelerating acoustic beams are selected to realize the BAAF.The working bandwidth of the BAAF based on our ATS could reach ~0.4 k Hz.It is found that by adjusting the distance between two flat AMs,the focal length and intensity of the bidirectional focusing could easily be modulated.Because the distance between two flat AMs is large enough,the BAAF even could be converted into a unidirectional acoustic focusing.The proposed BAAF may find applications in non-destructive evaluation,biomedical imaging and medical diagnosis.展开更多
A phase-shifting digital holography scheme developed to investigate internal defects in artworks is described. Phase-shifting is utilized to obtain a clear reconstructed object wave from a rough surface texture. A rev...A phase-shifting digital holography scheme developed to investigate internal defects in artworks is described. Phase-shifting is utilized to obtain a clear reconstructed object wave from a rough surface texture. A reverse-transform algorithm is employed to reconstruct the object wave on its original position of unknown distance or the imaging position from the object wave information on the holographic plane. To get the clearest reconstruction the exact registration of the unknown distance is determined by applying the intensity sum as the auto-focusing function, The spatial resolution of the reconstruction image is also investigated for a variety of affecting factors. Laboratory results of reconstruction images under deformation are presented.展开更多
基金Supported by the National Natural Science Foundation of China under Grant Nos 41274134 and 81527901the '12th Five-Year Plan' Period for Informatization Project in Supercomputing Key Demonstration of Chinese Academy of Sciences under Grant No XXH12503-02-02-2(07)
文摘The phase relation of harmonics in high-intensity focused ultrasound is investigated numerically and experimen- tally. The nonlinear Westervelt equation is solved to model nonlinear focused sound field by using the finite difference time domain method. Experimental waveforms are measured by a robust needle hydrophone. Then the relative phase quantity is introduced and obtained by using the zero-phase filter. The results show that the nth harmonic relative phase quantity is approximately (n - 1) π/3 at geometric center and increases along the axial direction. Moreover, the relative phase quantity decreases with the increase of source amplitude. This phase relation gives an explanation of some nonlinear phenomena such as the discrepancy of positive and negative pressure.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11774137 and 11404147)the Major Program of the National Natural Science Foundation of China(Grant No.51239005)+2 种基金the Natural Science Foundation of Jiangsu Province,China(Grant Nos.BK20140519 and BK20140523)the Jiangsu Qing Lan Project,Chinathe Practice Innovation Training Program Projects for Industrial Center of Jiangsu University,China
文摘We realize broadband acoustic focusing effect by employing two symmetric Airy beams generated from phased arrays,in which the units of the phased arrays consist of different numbers of cavity structures, each of which is composed of a square cavity and two inclined channels in air. The exotic phenomenon arises from the energy overlapping of the two symmetric Airy beams. Besides, we demonstrate the focusing performance with high self-healing property, and discuss the effects of structure parameters on focusing performance, and present the characteristics of the cavity structure with straight channels. Compared with other acoustic lenses, the proposed acoustic lens has advantages of broad bandwidth(about 1.4 kHz), high self-healing property of focusing performance, and free adjustment of focal length. Our finding should have great potential applications in ultrasound imaging and medical diagnosis.
文摘A liquid-phase isoelectric focusing electrophoresis system(Rotofor) was used as the prefractionation tool for the sample preparation in the MALDI-MS analysis of a protein mixture. Each fraction collected was then directly subjected to MALDI-TOF-MS analysis. By this approach, we are able to resolve two types of hemoglobins, A and C, which cannot be successfully separated by means of the traditional SDS-PAGE method.
文摘We propose a new approach for generating a multiple focal spot segment of subwavelength size, by tight focusing of a phase modulated radially polarized Laguerre Bessel Gaussian beam. The focusing properties are investigated theoretically by .vector diffraction theory. We observe that the focal segment with multiple focal structures is separated with different axial distances and a super long dark channel can be generated by properly tuning the phase of the incident radially polarized Laguerre Bessel Gaussian beam. We presume that such multiple focal patterns and high intense beam may find applications in atom optics, optical manipulations and multiple optical trapping.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11774137 and 51779107)the Six-Talent Peaks Project in Jiangsu Province,China(Grant No.GDZB-019)+2 种基金the China Postdoctoral Science Foundation(Grant No.2017M621643)the Natural Science Foundation of Jiangsu Higher Educational Institutions of China(Grant No.18KJB140003)the Practice Innovation Training Program Projects for Jiangsu University(Grant No.201710299023Z)and for the Industrial Center of Jiangsu University
文摘We report the realization of broadband reflected acoustic focusing lenses based on thermoacoustic phased arrays of Bessel-like beams, in which the units of phase manipulation are composed of three rigid insulated boundaries and a thermal insulation film in air with different temperatures. Based on these units, we realize a reflected focusing lens which can focus reflected acoustic energy on a line, and its fractional bandwidth can reach about 0.29. In addition, we discuss the influences of the base angle of Bessel-like beam, the number of basic unit, and the variation of unit temperature on focusing performances in details. Furthermore, the reflected focusing lens for the cylindrical acoustic wave based on the Bessel-like beam is also demonstrated. The proposed focusing lens has the advantages of a broad working bandwidth, large focus size,and high robustness, which may provide possibilities for the design and application of acoustic lenses.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11774377 and 11574343)。
文摘We investigate the beam focusing technology of shear-vertical(SV) waves for a contact-type linear phased array to overcome the shortcomings of conventional wedge transducer arrays. The numerical simulation reveals the transient excitation and propagation characteristics of SV waves. It is found that the element size plays an important role in determining the transient radiation directivity of SV waves. The transient beam focusing characteristics of SV waves for various array parameters are deeply studied. It is particularly interesting to see that smaller element width will provide the focused beam of SV waves with higher quality, while larger element width may result in erratic fluctuation of focusing energy around the focal point. There exists a specific range of inter-element spacing for optimum focusing performance. Moreover, good beam focusing performance of SV waves can be achieved only at high steering angles.
基金financially supported by the State Key Research and Development Program of China(Grant No.2016YFC1401405)the National Natural Science Foundation of China(Grant Nos.51779038 and 51279028)
文摘Based on phase focusing theory, focusing waves with different spectral types and breaking severities were generated in a wave flume. The time series of surface elevation fluctuation along the flume were obtained by utilizing 22 wave probes mounted along the mid-stream of the flume. Based on the wave spectrum obtained using fast Fourier transform(FFT), the instability characteristics of the energy spectrum were reported in this paper. By analyzing the variation of total spectral energy, the total spectral energy after wave breaking was found to clearly decrease, and the loss value and ratio gradually increased and tended to stabilize with the enhancement of breaking severity for different spectral types. When wave breaking occurred, the energy loss was primarily in a high-frequency range of f/fp>1.0, and energy gain was primarily in a low-frequency range of f/fp<1.0. As the breaking severity increased, the energy gain-loss ratio decreased gradually, which demonstrates that the energy was mostly dissipated. For plunging waves, the energy gain-loss ratio reached 24% for the constant wave steepness(CWS) spectrum, and was slightly larger at approximately 30% for the constant wave amplitude(CWA) spectrum, and was the largest at approximately 42% for the Pierson-Moskowitz(PM) spectrum.
基金Project supported by the Program for New Century Excellent Talents in University of China (Grant No 06-0450)the National Natural Science Foundation of China (Grant No 10774071)the Natural Science Foundation of Jiangsu Province, China (Grant No BK2007518)
文摘This article theoretically studies the influence of inhomogeneous abdominal walls on focused therapeutic ultrasound based on the phase screen model. An inhomogeneous tissue is considered as a combination of a homogeneous medium and a phase aberration screen. Variations of acoustic parameters such as peak positive pressure, peak negative pressure, and acoustic intensity are discussed with respect to the phase screen statistics of human abdominal walls. Results indicate that the abdominal wall can result in energy loss of the sound in the focal plane. For a typical human abdominal wall with correlation length of 7.9 mm and variance of 0.36, the peak acoustic intensity radiated from a 1MHz transmitter with a radius of 30 mm can be reduced by about 14% at the focal plane.
基金supported by the National Natural Science Foundation of China (Grant No.50779004)
文摘Four focusing models for generation of freak waves are presented. An extreme wave focusing model is presented on the basis of the enhanced High-Order Spectral (HOS) method and the importance of the nonlinear wave-wave interaction is evaluated by comparison of the calculated results with experimental and theoretical data. Based on the modification of the Longuet-Higgins model, four wave models for generation of freak waves (a. extreme wave model + random wave model; b. extreme wave model + regular wave model; e. phase interval modulation wave focusing model; d. number modulation wave focusing model with the same phase) are proposed. By use of different energy distribution techniques in the four models, freak wave events are obtained with different Hmax/Hs in finite space and time.
基金The Key Technology Program,the Ministry of Education of China under contract No.104061
文摘Based on the Longuet-Higgins wave model theory, the previews studies have shown that freak waves can be generated in finite space and time successfully. However, as to generating high nonlinear freak waves, the simulation results will be unrealistic. Therefore, a modified phase modulation method for simulating high nonlinear freak waves was developed. The surface elevations of some wave components at certain time and place are positive by modulating the corresponding random initial phases, then the total surface elevation at the focused point is enhanced and furthermore a freak wave event is generated. The new method can not only make the freak wave occur at certain time and place, but also make the simulated wave surface time series satisfy statistical properties of the realistic sea state and keep identical with the target wave spectrum. This numerical approach is of good precision and high efficiency by the comparisons of the simulated freak waves and the recorded freak waves.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.11704193,11674175,and 11704192)the "333" Project of Jiangsu Province,China(Grant No.BRA2017451)the Postgraduate Research&Practice Innovation Program of Jiangsu Province,China(Grant No.KYCX18_1185)
文摘We design an asymmetric transmission system(ATS)with two flat acoustic metasurfaces(AMs)to yield bidirectional asymmetric acoustic focusing(BAAF).The acoustic waves could be focused on both sides of the ATS with different focal lengths and intensities.To achieve high intensity energy concentration,the accelerating acoustic beams are selected to realize the BAAF.The working bandwidth of the BAAF based on our ATS could reach ~0.4 k Hz.It is found that by adjusting the distance between two flat AMs,the focal length and intensity of the bidirectional focusing could easily be modulated.Because the distance between two flat AMs is large enough,the BAAF even could be converted into a unidirectional acoustic focusing.The proposed BAAF may find applications in non-destructive evaluation,biomedical imaging and medical diagnosis.
文摘A phase-shifting digital holography scheme developed to investigate internal defects in artworks is described. Phase-shifting is utilized to obtain a clear reconstructed object wave from a rough surface texture. A reverse-transform algorithm is employed to reconstruct the object wave on its original position of unknown distance or the imaging position from the object wave information on the holographic plane. To get the clearest reconstruction the exact registration of the unknown distance is determined by applying the intensity sum as the auto-focusing function, The spatial resolution of the reconstruction image is also investigated for a variety of affecting factors. Laboratory results of reconstruction images under deformation are presented.