The complex [Mn(H2O)(phen)2(PAc)](ClO4) was synthesized and investigated by elemental analysis, molar conductivity, IR spectrum and X ray diffraction methods, where phen=1,10 phenanthroline and PAc=phenylac<IMG SRC...The complex [Mn(H2O)(phen)2(PAc)](ClO4) was synthesized and investigated by elemental analysis, molar conductivity, IR spectrum and X ray diffraction methods, where phen=1,10 phenanthroline and PAc=phenylac<IMG SRC="IMAGE/06200090.JPG" HEIGHT=11 WIDTH=12>etate group. The complex crystallizes in the triclinic space group, , with a=0.9289(2)nm,b=1.2425(2)nm,c=1.4791(3)nm,α=114.34(3)°,β=91.25(3)°,γ=104.65(1)°,V=1.4893(4)nm3,Z=2,F(000)=686,Dc=1.489g·cm-3,μ=0.589mm-1. The Mn?ion has a six coordinate distorted octahedral geometry with the four nitrogen atoms of two phen ligands,a coordinated water oxygen atom, and a carboxylate oxygen atom of PAc-. There is π πstacking interaction between two phen rings from two neighbor molecules.展开更多
首次采用毛细管电泳-安培检测法(CE-AD)同时测定了苯丙酮尿症(Phenylketonuria,PKU)患者尿液中的两种标志物:具有电活性的苯丙酮酸及非电活性的苯乙酸。考察了运行液添加剂、SDS浓度、工作电极电位等因素对分离和检测的影响。在优化实...首次采用毛细管电泳-安培检测法(CE-AD)同时测定了苯丙酮尿症(Phenylketonuria,PKU)患者尿液中的两种标志物:具有电活性的苯丙酮酸及非电活性的苯乙酸。考察了运行液添加剂、SDS浓度、工作电极电位等因素对分离和检测的影响。在优化实验条件下,两种标志物在15 m in内可实现基线分离。苯丙酮酸和苯乙酸的检出限(S/N=3)分别为0.50、0.92 mg/L。苯丙酮酸、苯乙酸浓度与峰高分别在3.0～1.0×103mg/L、2.0～5.0×103mg/L范围内呈良好线性,峰高与迁移时间的相对标准偏差分别为4.4%、3.2%(苯丙酮酸)和2.2%、4.3%(苯乙酸)。该方法已成功用于PKU患儿尿液中两种标志物的测定,且完全避免了尿液中尿酸对标志物测定的干扰,有望用于PKU患儿的早期无创诊断。展开更多
文摘The complex [Mn(H2O)(phen)2(PAc)](ClO4) was synthesized and investigated by elemental analysis, molar conductivity, IR spectrum and X ray diffraction methods, where phen=1,10 phenanthroline and PAc=phenylac<IMG SRC="IMAGE/06200090.JPG" HEIGHT=11 WIDTH=12>etate group. The complex crystallizes in the triclinic space group, , with a=0.9289(2)nm,b=1.2425(2)nm,c=1.4791(3)nm,α=114.34(3)°,β=91.25(3)°,γ=104.65(1)°,V=1.4893(4)nm3,Z=2,F(000)=686,Dc=1.489g·cm-3,μ=0.589mm-1. The Mn?ion has a six coordinate distorted octahedral geometry with the four nitrogen atoms of two phen ligands,a coordinated water oxygen atom, and a carboxylate oxygen atom of PAc-. There is π πstacking interaction between two phen rings from two neighbor molecules.
文摘首次采用毛细管电泳-安培检测法(CE-AD)同时测定了苯丙酮尿症(Phenylketonuria,PKU)患者尿液中的两种标志物:具有电活性的苯丙酮酸及非电活性的苯乙酸。考察了运行液添加剂、SDS浓度、工作电极电位等因素对分离和检测的影响。在优化实验条件下,两种标志物在15 m in内可实现基线分离。苯丙酮酸和苯乙酸的检出限(S/N=3)分别为0.50、0.92 mg/L。苯丙酮酸、苯乙酸浓度与峰高分别在3.0～1.0×103mg/L、2.0～5.0×103mg/L范围内呈良好线性,峰高与迁移时间的相对标准偏差分别为4.4%、3.2%(苯丙酮酸)和2.2%、4.3%(苯乙酸)。该方法已成功用于PKU患儿尿液中两种标志物的测定,且完全避免了尿液中尿酸对标志物测定的干扰,有望用于PKU患儿的早期无创诊断。
