A convenient and facile one-pot synthesis of stable phosphorus ylides and 1,4-diionic organophosphorus compounds is reported by the reaction of triphenylphosphine, dialkylacetylenedicarboxylates and N-H, C-H or S-H ac...A convenient and facile one-pot synthesis of stable phosphorus ylides and 1,4-diionic organophosphorus compounds is reported by the reaction of triphenylphosphine, dialkylacetylenedicarboxylates and N-H, C-H or S-H acids in the presence of polyethyleneglycol （PEG）, β-cyclodextrin （β-CD）, glycerine （Gly） or ethyleneglycol （EG） in water. This methodology is of interest due to the use of water as a solvent, thus minimizing the cost operational hazards, and environmental pollution.展开更多
The zwitterionic intermediate generated from the reaction of triphenylphosphine with electron deficient acety- lenic compounds was trapped by various NH acids. The synthesis resulted in a new class of highly functiona...The zwitterionic intermediate generated from the reaction of triphenylphosphine with electron deficient acety- lenic compounds was trapped by various NH acids. The synthesis resulted in a new class of highly functionalized heterocyclic compounds. Some of the reactions produced E and Z isomers. And the stability and transformation of them were studied by dynamic 1H NMR and density functional theory （DFT） calculations.展开更多
基金support from the Research Council of University of Sistan and Baluchestan,Iran
文摘A convenient and facile one-pot synthesis of stable phosphorus ylides and 1,4-diionic organophosphorus compounds is reported by the reaction of triphenylphosphine, dialkylacetylenedicarboxylates and N-H, C-H or S-H acids in the presence of polyethyleneglycol （PEG）, β-cyclodextrin （β-CD）, glycerine （Gly） or ethyleneglycol （EG） in water. This methodology is of interest due to the use of water as a solvent, thus minimizing the cost operational hazards, and environmental pollution.
文摘The zwitterionic intermediate generated from the reaction of triphenylphosphine with electron deficient acety- lenic compounds was trapped by various NH acids. The synthesis resulted in a new class of highly functionalized heterocyclic compounds. Some of the reactions produced E and Z isomers. And the stability and transformation of them were studied by dynamic 1H NMR and density functional theory （DFT） calculations.
