In this paper, we introduce photon-added and photon-subtracted squeezed vacuum state （PASV and PSSV） and obtain their normalized factors, which have the similar forms involved in Lengendre polynomials. Moreover, we ...In this paper, we introduce photon-added and photon-subtracted squeezed vacuum state （PASV and PSSV） and obtain their normalized factors, which have the similar forms involved in Lengendre polynomials. Moreover, we give the compact expressions of Wigner function, which are related to single-variable Hermite polynomials. Especially, we compare their nonclassicality in terms of Mandel Q-factor and the negativity of Wigner function.展开更多
We construct photon-subtracted(-added)thermo vacuum state by normalizing them.As their application we derive some new generating function formulas of Jacobi polynomials,which may be applied to study other problems in ...We construct photon-subtracted(-added)thermo vacuum state by normalizing them.As their application we derive some new generating function formulas of Jacobi polynomials,which may be applied to study other problems in quantum mechanics.This will also stimulate the research of mathematical physics in the future.展开更多
This paper investigates the decoherence of photo-subtracted squeezed vacuum state （PSSVS） in dissipative channel by describing its statistical properties with time evolution such as Wigner function, Husimi function,...This paper investigates the decoherence of photo-subtracted squeezed vacuum state （PSSVS） in dissipative channel by describing its statistical properties with time evolution such as Wigner function, Husimi function, and tomogram. It first calculates the normalization factor of PSSVS related to Legendre polynomial. After deriving the normally ordered density Operator of PSSVS in dissipative channel, one obtains the explicit analytical expressions of time evolution of PSSVS＇s statistical distribution function. It finds that these statistical distributions loss their non-Gaussian nature and become Gaussian at last in the dissipative environment as expected.展开更多
By using the technique of integration within an ordered product of operators, the normal ordered density operator of the photon-subtracted squeezed thermal state （PSSTS） is derived. Then the corresponding Wigner fun...By using the technique of integration within an ordered product of operators, the normal ordered density operator of the photon-subtracted squeezed thermal state （PSSTS） is derived. Then the corresponding Wigner function is presented by using the coherent state representation of the Wigner operator. The nonclassical properties of the PSSTS are discussed based on the negativity of the Wigner function.展开更多
We study the Joule-Thomson expansion of the regular black hole in an anti-de Sitter background,and obtain the inversion temperature for the Bardeen-AdS black hole in the extended phase space.We investigate the isentha...We study the Joule-Thomson expansion of the regular black hole in an anti-de Sitter background,and obtain the inversion temperature for the Bardeen-AdS black hole in the extended phase space.We investigate the isenthalpic and inversion curves for the Bardeen-AdS black hole in the T-P plane and find that the intersection points between them are exactly the inversion points discriminating the heating from the cooling process.The inversion curve for the regular(Bardeen)-AdS black hole is not closed and there is only a lower inversion curve,in contrast to the Van der Waals fluid.Most importantly,we find that the ratio between the minimum inversion temperature and the critical temperature for the regular(Bardeen)-AdS black hole is 0.536622,which is larger than any known ratio for the singular black hole.The large ratio for the Bardeen-AdS black hole may be due to the repulsive de Sitter core near the origin of the regular black hole.展开更多
Background The nucleotide-binding oligomerization domain-like receptor protein 12(NLRP12)-autoinflammatory disorder(NLRP12-AD)is a rare autoinflammatory disease characterized by recurrent fever,rash as well as musculo...Background The nucleotide-binding oligomerization domain-like receptor protein 12(NLRP12)-autoinflammatory disorder(NLRP12-AD)is a rare autoinflammatory disease characterized by recurrent fever,rash as well as musculoskeletal symptoms,which is rarely reported in Asian populations.Methods Three cases of NLRP12-AD presented to our hospital were studied after parental consents were obtained.Clinical presentations were recorded on a standardized case report form.Mutations of NLRP12 were detected by primary immunodeficiency disease panels and further examined by Sanger sequencing.PubMed literature search for relevant studies of systemic autoinflammatory disorders,especially NLRP12-AD between January,2000 and January,2019 was carried and the clinical data were summarized.Comparisons were made between groups in terms of onset age and of ethnicity.Results All our patients presented with fever,rash and arthritis/arthralgia,and sensorineural as well as sensorineural deafness(1/3),uveitis(1/3),abdominal pain(1/3),and myalgia(1/3).Two novel mutation variations,p.W581X and p.L558R,are reported here.In addition,we also found that two patients inherited the mutated alleles from their healthy parents,and this may be evidence of haploinsutficiency.Conclusions Although the genotypes are similar,the clinical manifestations between Chinese patients and Western patients vary thus highlighting the possible influence of ethnic and environmental factors.On the other hand,some genetic mutations may lead to specific phenotype,as we have found a high prevalence of sensorineural hearing loss among p.R284X patients.展开更多
Background: Patient-to-patient variability in the degree to which β-amyloid, tau and neurodegeneration impact cognitive decline in Alzheimer’s disease (AD) complicates disease modeling and treatment. However, the un...Background: Patient-to-patient variability in the degree to which β-amyloid, tau and neurodegeneration impact cognitive decline in Alzheimer’s disease (AD) complicates disease modeling and treatment. However, the underlying mechanisms leading to cognitive resilience are not resolved. We hypothesize that the variability in cognitive function and loss relates to neuronal resilience of the hippocampal GABAergic network. Methods: We compared TgF344-AD and non-transgenic littermate rats at 9, 12, and 15 months of age. Neurons, β-amyloid plaques and tau inclusions were quantified in hippocampus and entorhinal cortex. Somatostatin (SST) and parvalbumin (PVB) interneurons were traced to examine hippocampal neuroplasticity and cognition was tested in the Barnes maze. Results: The 9-month-old TgF344-AD rats exhibited loss of neurons in the entorhinal cortex and hippocampus. Hippocampal neuronal compensation was observed in 12-month TgF344-AD rats, with upregulation of GABAergic interneuronal marker. By 15 months, the TgF344-AD rats had robust loss of excitatory and inhibitory neurons. β-Amyloid and tau pathology accumulated continuously across age. SST interneurons exhibited tau inclusions and atrophy from 9 months, whereas PVB interneurons were resilient until 15 months. The hippocampal PVB circuit underwent neuroplastic reorganization with increased dendritic length and complexity in 9- and 12-month-old TgF344- AD rats, before atrophy at 15 months. Strikingly, 12-month-old TgF344-AD rats were resilient in executive function and cognitive flexibility. Cognitive resilience in TgF344-AD rats occurred as maintenance of function between 9 and 12 months of age despite progressive spatial memory deficits, and was sustained by PVB neuroplasticity. Conclusions: Our results demonstrate the inherent neuronal processes leading to cognitive maintenance, and describe a novel finding of endogenous cognitive resilience in an AD model.展开更多
基金supported by the National Natural Science Foundation of China (Grant No.11047133)the Natural Science Foundation of Jiangxi Province of China (Grant No.2010GQW0027)+1 种基金the Key Program Foundation of Ministry of Education of China (Grant No.210115)the Research Foundation of the Education Department of Jiangxi Province of China (Grant Nos.GJJ10097 and GJJ11390)
文摘In this paper, we introduce photon-added and photon-subtracted squeezed vacuum state （PASV and PSSV） and obtain their normalized factors, which have the similar forms involved in Lengendre polynomials. Moreover, we give the compact expressions of Wigner function, which are related to single-variable Hermite polynomials. Especially, we compare their nonclassicality in terms of Mandel Q-factor and the negativity of Wigner function.
基金Doctoral Scientific Research Foundation of Chaohu College(No.KYQD-201407)
文摘We construct photon-subtracted(-added)thermo vacuum state by normalizing them.As their application we derive some new generating function formulas of Jacobi polynomials,which may be applied to study other problems in quantum mechanics.This will also stimulate the research of mathematical physics in the future.
基金supported by the National Natural Science Foundation of China (Grant No. 10775097)the Key Program Foundation of the Ministry of Education of China (Grant No. 210115)the Research Foundation of the Education Department of Jiangxi Province of China (Grant No. GJJ10097)
文摘This paper investigates the decoherence of photo-subtracted squeezed vacuum state （PSSVS） in dissipative channel by describing its statistical properties with time evolution such as Wigner function, Husimi function, and tomogram. It first calculates the normalization factor of PSSVS related to Legendre polynomial. After deriving the normally ordered density Operator of PSSVS in dissipative channel, one obtains the explicit analytical expressions of time evolution of PSSVS＇s statistical distribution function. It finds that these statistical distributions loss their non-Gaussian nature and become Gaussian at last in the dissipative environment as expected.
基金Project supported by the National Natural Science Foundation of China (Grant Nos 10775097 and 10874174)the Research Foundation of the Education Department of Jiangxi Province of China
文摘By using the technique of integration within an ordered product of operators, the normal ordered density operator of the photon-subtracted squeezed thermal state （PSSTS） is derived. Then the corresponding Wigner function is presented by using the coherent state representation of the Wigner operator. The nonclassical properties of the PSSTS are discussed based on the negativity of the Wigner function.
基金Supported by the Program for NCET-12-1060by the Sichuan Youth Science and Technology Foundation(2011JQ0019)+3 种基金by FANEDD(201319)by Ten Thousand Talent Program of Sichuan Provinceby Sichuan Natural Science Foundation(16ZB0178)by the starting funds of China West Normal University(17YC513,17C050)
文摘We study the Joule-Thomson expansion of the regular black hole in an anti-de Sitter background,and obtain the inversion temperature for the Bardeen-AdS black hole in the extended phase space.We investigate the isenthalpic and inversion curves for the Bardeen-AdS black hole in the T-P plane and find that the intersection points between them are exactly the inversion points discriminating the heating from the cooling process.The inversion curve for the regular(Bardeen)-AdS black hole is not closed and there is only a lower inversion curve,in contrast to the Van der Waals fluid.Most importantly,we find that the ratio between the minimum inversion temperature and the critical temperature for the regular(Bardeen)-AdS black hole is 0.536622,which is larger than any known ratio for the singular black hole.The large ratio for the Bardeen-AdS black hole may be due to the repulsive de Sitter core near the origin of the regular black hole.
基金This study was supported by Beijing Association for Golden Bridge Engineering Seed Found of Beijing Association for Science and Technology(JQ17032)the Capital Health Research and Development of Special(2016-2-40114),CAMS Initiative for Innovative Medicine(2016-I2M-1-008),CAMS Central Public Welfare Scientific Research Institute Basal Research Expenses to HW(2016ZX310182-1),and Public Welfare Scientific Research Project of China(201402012).
文摘Background The nucleotide-binding oligomerization domain-like receptor protein 12(NLRP12)-autoinflammatory disorder(NLRP12-AD)is a rare autoinflammatory disease characterized by recurrent fever,rash as well as musculoskeletal symptoms,which is rarely reported in Asian populations.Methods Three cases of NLRP12-AD presented to our hospital were studied after parental consents were obtained.Clinical presentations were recorded on a standardized case report form.Mutations of NLRP12 were detected by primary immunodeficiency disease panels and further examined by Sanger sequencing.PubMed literature search for relevant studies of systemic autoinflammatory disorders,especially NLRP12-AD between January,2000 and January,2019 was carried and the clinical data were summarized.Comparisons were made between groups in terms of onset age and of ethnicity.Results All our patients presented with fever,rash and arthritis/arthralgia,and sensorineural as well as sensorineural deafness(1/3),uveitis(1/3),abdominal pain(1/3),and myalgia(1/3).Two novel mutation variations,p.W581X and p.L558R,are reported here.In addition,we also found that two patients inherited the mutated alleles from their healthy parents,and this may be evidence of haploinsutficiency.Conclusions Although the genotypes are similar,the clinical manifestations between Chinese patients and Western patients vary thus highlighting the possible influence of ethnic and environmental factors.On the other hand,some genetic mutations may lead to specific phenotype,as we have found a high prevalence of sensorineural hearing loss among p.R284X patients.
基金the Canadian Institutes of Health Research Project Grant,PJY155983(J.M.)Canada Research Chairs Program(J.M.)and National Institutes of Health R01 AG057665-02(J.M.).
文摘Background: Patient-to-patient variability in the degree to which β-amyloid, tau and neurodegeneration impact cognitive decline in Alzheimer’s disease (AD) complicates disease modeling and treatment. However, the underlying mechanisms leading to cognitive resilience are not resolved. We hypothesize that the variability in cognitive function and loss relates to neuronal resilience of the hippocampal GABAergic network. Methods: We compared TgF344-AD and non-transgenic littermate rats at 9, 12, and 15 months of age. Neurons, β-amyloid plaques and tau inclusions were quantified in hippocampus and entorhinal cortex. Somatostatin (SST) and parvalbumin (PVB) interneurons were traced to examine hippocampal neuroplasticity and cognition was tested in the Barnes maze. Results: The 9-month-old TgF344-AD rats exhibited loss of neurons in the entorhinal cortex and hippocampus. Hippocampal neuronal compensation was observed in 12-month TgF344-AD rats, with upregulation of GABAergic interneuronal marker. By 15 months, the TgF344-AD rats had robust loss of excitatory and inhibitory neurons. β-Amyloid and tau pathology accumulated continuously across age. SST interneurons exhibited tau inclusions and atrophy from 9 months, whereas PVB interneurons were resilient until 15 months. The hippocampal PVB circuit underwent neuroplastic reorganization with increased dendritic length and complexity in 9- and 12-month-old TgF344- AD rats, before atrophy at 15 months. Strikingly, 12-month-old TgF344-AD rats were resilient in executive function and cognitive flexibility. Cognitive resilience in TgF344-AD rats occurred as maintenance of function between 9 and 12 months of age despite progressive spatial memory deficits, and was sustained by PVB neuroplasticity. Conclusions: Our results demonstrate the inherent neuronal processes leading to cognitive maintenance, and describe a novel finding of endogenous cognitive resilience in an AD model.
