The study integrates both the geological and geophysical mapping techniques for groundwater potential studies at Ekwegbe-Agu and the environs, Enugu state, Nigeria for optimal citing of borehole. Located in the Anambr...The study integrates both the geological and geophysical mapping techniques for groundwater potential studies at Ekwegbe-Agu and the environs, Enugu state, Nigeria for optimal citing of borehole. Located in the Anambra Basin between latitudes 6˚43'N and 6˚47'N and longitudes 7˚28'E and 7˚32'E, it is stratigraphycally underlain by, from bottom to top, the Enugu/Nkporo, Mamu and Ajali Formation respectively, a complex geology that make citing of productive borehole in the area problematic leading to borehole failure and dry holes due to inadequate sampling. The study adopted a field and analytic sampling approach, integrating field geological, electrical resistivity and self-potential methods. The software, SedLog v3.1, InterpexIx1Dv.3, and Surfer v10 were employed for the data integration and interpretation. The result of the geological field and borehole data shows 11 sedimentary facies consisting of sandstone, shales and heterolith of sandstone/shale, with the aquifer zone mostly prevalent in the more porous sand-dominated horizons. Mostly the AK and HK were the dominant curve types. An average of 6 geo-electric layers were delineated across all transects with resistivity values ranging from 25.42 - 105.85 Ωm, 186.38 - 3383.3 Ωm, and 2992 - 6286.4 Ωm in the Enugu, Mamu and Ajali Formations respectively. The resistivity of the main aquifer layer ranges from 1 to 500 Ωm. The aquifer thickness within the study area varies between 95 and 140 m. The western and northwestern part of the study area which is underlain mainly by the Ajali Formation showed the highest groundwater potential in the area and suitable for citing productive boreholes.展开更多
A FISH procedure was adopted to physical mapping rice RFLP marker RZ69 and the BAC clone 38J9 screened by RZ69 which is linked to gene Bph3 in Oryza saliva L. and O. officinalis Well ex: Watt. The FISH results showed ...A FISH procedure was adopted to physical mapping rice RFLP marker RZ69 and the BAC clone 38J9 screened by RZ69 which is linked to gene Bph3 in Oryza saliva L. and O. officinalis Well ex: Watt. The FISH results showed that both 38J9 and RZ69 were located in the middle of 4S in O. officinalis and the centromere area of 4S in O. sativa. In O. officinalis the percentage distances from the centromere to the hybridization sites were 20.00 +/- 5.40 and 22.12 +/- 3.44, the detection rates were 50.00% and 6.14%, but in O. sativa they were 0 and 0, 56.10% and 6.29% correspondingly. The results obtained from the BAC and RFLP clone were almost the same in the cultivated rice and O. officinalis. It was suggested that die marker RZ69 of the cultivated rice and its homologous sequence in O. officinalis were in the same BAC clone, the homologous sequence of Bph3 in O. officinalis should be located at the sites hybridized by both RZ69 and 38J9. Many signals on different chromosomes of O. officinalis were observed under no blocking with Cot-1 DNA, showing that the repetitive sequences were also homologous between O. sativa and O. officinalis. The identification of chromosome 4 of O. officinalis is based on comparative map with RG214 and BAC clone screened by RG214. The feasibility of comparative physical mapping performed between O. sativa and O. officinalis with rice BAC clones was discussed.展开更多
A physical value mapping （PVM） algorithm based on finite element mesh from the stamped part in stamping process to the product is presented, In order to improve the efficiency of the PVM algorithm, a search way from...A physical value mapping （PVM） algorithm based on finite element mesh from the stamped part in stamping process to the product is presented, In order to improve the efficiency of the PVM algorithm, a search way from the mesh of the product to the mesh of the stamped part will be adopted. At the same time, the search process is divided into two steps： entire search （ES） and local search （LS）, which improve the searching efficiency. The searching area is enlarged to avoid missing projection elements in ES process. An arc-length method is introduced in LS process. The validity is confirmed by the results of the complex industry-forming product.展开更多
Wheat powdery mildew （Pro） is a major disease of wheat worldwide. During the past years, numerous studies have been published on molecular mapping of Pm resistance gene（s） in wheat. We summarized the relevant find...Wheat powdery mildew （Pro） is a major disease of wheat worldwide. During the past years, numerous studies have been published on molecular mapping of Pm resistance gene（s） in wheat. We summarized the relevant findings of 89 major re- sistance gene mapping studies and 25 quantitative trait loci （QTL） mapping studies. Major Pm resistance genes and QTLs were found on all wheat chromosomes, but the Pm resistance genes/QTLs were not randomly distributed on each chromosome of wheat. The summarized data showed that the A or B genome has more major Pm resistance genes than the D genome and chromosomes 1A, 2A, 2B, 5B, 5D, 6B, 7A and 7B harbor more major Pm resistance genes than the other chromosomes. For adult plant resistance （APR） genes/QTLs, B genome of wheat harbors more APR genes than A and D genomes, and chromo- somes 2A, 4A, 5A, 1B, 2B, 3B, 5B, 6B, 7B, 2D, 5D and 7D harbor more Pm resistance QTLs than the other chromosomes, suggesting that A genome except 1A, 3A and 6A, B genome except 4B, D genome except 1D, 3D, 4D, and 6D play an impor- tant role in wheat combating against powdery mildew. Furthermore, Pm resistance genes are derived from wheat and its rela- tives, which suggested that the resistance sources are diverse and Pm resistance genes are diverse and useful in combating against the powdery mildew isolates. In this review, four APR genes, Pm38/Lr34/Yr18/Sr57, Pm46/Lr67/Yr46/Sr55, Pm？/Lr27/Yr30/ SY2 and Pm39/Lr46/Yr29, are not only resistant to powdery mildew but also effective for rust diseases in the field, indicating that such genes are stable and useful in wheat breeding programmes. The summarized data also provide chromosome locations or linked markers for Pm resistance genes/QTLs. Markers linked to these genes can also be utilized to pyramid diverse Pm resis- tance genes/QTLs more efficiently by marker-assisted selection.展开更多
The eastern Mediterranean is a tectonically complex region evolving in the long term located in the midst of the progressive Afro-Eurasian collision. Despite years of investigation, its geological-geophysical structur...The eastern Mediterranean is a tectonically complex region evolving in the long term located in the midst of the progressive Afro-Eurasian collision. Despite years of investigation, its geological-geophysical structure is not completely known. At the same time, the recent discovery of large gas deposits has attracted the attention of many researchers to this region. For instance, the latest U. S. Geological Survey estimates using conventional assessment methodology suggest that there are on the order of 1.7 billion barrels of recoverable oil and more than 4 trillion m3 of recoverable gas in the Levant Basin [1]. This highlights the need for analysis of the paleogeographical conditions that can yield deep paleotectonic criteria for oil and gas discovery in this region. For this purpose, isopach maps of the Middle-Upper Jurassic and Lower Cretaceous were generated from detailed examinations of numerous well sections and the most significant outcroppings in the eastern Mediterranean. The maps confirm an earlier model of continental accretion [2]. In particular, abrupt changes in the trend and thickness of the Early Mesozoic formations coincide with the terrane boundaries. These compiled isopach maps also pinpoint significant distinctions between the Arabian and Sinai plates on the one hand and the Syrian arc on the other. A new tectonic map of the eastern Mediterranean is presented that first of all integrates geophysical satellite-derived gravity and airborne magnetic fields, as well as tectonic-structural, paleogeographical and facial analyses. The results have clear implications for hydrocarbon prospecting in this region.展开更多
Background:The Compendium of Physical Activities was published in 1993 to improve the comparability of energy expenditure values assigned to self-reported physical activity(PA)across studies.The original version was u...Background:The Compendium of Physical Activities was published in 1993 to improve the comparability of energy expenditure values assigned to self-reported physical activity(PA)across studies.The original version was updated in 2000,and again in 2011,and has been widely used to support PA research,practice,and public health guidelines.Methods:This 2024 update was tailored for adults 19-59 years of age by removing data from those≥60 years.Using a systematic review and supplementary searches,we identified new activities and their associated measured metabolic equivalent(MET)values(using indirect calorimetry)published since 2011.We replaced estimated METs with measured values when possible.Results:We screened 32,173 abstracts and 1507 full-text papers and extracted 2356 PA energy expenditure values from 701 papers.We added303 new PAs and adjusted 176 existing MET values and descriptions to reflect the addition of new data and removal of METs for older adults.We added a Major Heading(Video Games).The 2024 Adult Compendium includes 1114 PAs(912 with measured and 202 with estimated values)across 22 Major Headings.Conclusion:This comprehensive update and refinement led to the creation of The 2024 Adult Compendium,which has utility across research,public health,education,and healthcare domains,as well as in the development of consumer health technologies.The new website with the complete lists of PAs and supporting resources is available at https://pacompendium.com.展开更多
Background:Lifestyle plays an important role in preventing and managing gastroesophageal reflux disease(GERD).In response to the conflicting results in previous studies,we performed a systematic review and meta-analys...Background:Lifestyle plays an important role in preventing and managing gastroesophageal reflux disease(GERD).In response to the conflicting results in previous studies,we performed a systematic review and meta-analysis to investigate this association.Methods:Relevant studies published until January 2023 were retrieved from 6 databases,and the prevalence of symptomatic gastroesophageal reflux(GER)or GERD was determined from the original studies.A random effects model was employed to meta-analyze the association by computing the pooled relative risk(RR)with 95%confidence intervals(95%CIs).Furthermore,subgroup and dose-response analyses were performed to explore subgroup differences and the association between cumulative physical activity(PA)time and GERD.Results:This meta-analysis included 33 studies comprising 242,850 participants.A significant negative association was observed between PA and the prevalence of symptomatic GER(RR=0.74,95%CI:0.66-0.83;p<0.01)or GERD(RR=0.80,95%CI:0.76-0.84;p<0.01),suggesting that engaging in PA might confer a protective benefit against GERD.Subgroup analyses consistently indicated the presence of this association across nearly all subgroups,particularly among the older individuals(RR_(<40 years):RR_(≥40 years)=0.85:0.69,p<0.01)and smokers(RR_(smoker):RR_(non-smoker)=0.67:0.82,p=0.03).Furthermore,a dose-response analysis revealed that individuals who engaged in 150 min of PA per week had a 72.09%lower risk of developing GERD.Conclusion:Maintaining high levels of PA decreased the risk of GERD,particularly among older adults and smokers.Meeting the recommended PA level of 150 min per week may significantly decrease the prevalence of GERD.展开更多
文摘The study integrates both the geological and geophysical mapping techniques for groundwater potential studies at Ekwegbe-Agu and the environs, Enugu state, Nigeria for optimal citing of borehole. Located in the Anambra Basin between latitudes 6˚43'N and 6˚47'N and longitudes 7˚28'E and 7˚32'E, it is stratigraphycally underlain by, from bottom to top, the Enugu/Nkporo, Mamu and Ajali Formation respectively, a complex geology that make citing of productive borehole in the area problematic leading to borehole failure and dry holes due to inadequate sampling. The study adopted a field and analytic sampling approach, integrating field geological, electrical resistivity and self-potential methods. The software, SedLog v3.1, InterpexIx1Dv.3, and Surfer v10 were employed for the data integration and interpretation. The result of the geological field and borehole data shows 11 sedimentary facies consisting of sandstone, shales and heterolith of sandstone/shale, with the aquifer zone mostly prevalent in the more porous sand-dominated horizons. Mostly the AK and HK were the dominant curve types. An average of 6 geo-electric layers were delineated across all transects with resistivity values ranging from 25.42 - 105.85 Ωm, 186.38 - 3383.3 Ωm, and 2992 - 6286.4 Ωm in the Enugu, Mamu and Ajali Formations respectively. The resistivity of the main aquifer layer ranges from 1 to 500 Ωm. The aquifer thickness within the study area varies between 95 and 140 m. The western and northwestern part of the study area which is underlain mainly by the Ajali Formation showed the highest groundwater potential in the area and suitable for citing productive boreholes.
文摘A FISH procedure was adopted to physical mapping rice RFLP marker RZ69 and the BAC clone 38J9 screened by RZ69 which is linked to gene Bph3 in Oryza saliva L. and O. officinalis Well ex: Watt. The FISH results showed that both 38J9 and RZ69 were located in the middle of 4S in O. officinalis and the centromere area of 4S in O. sativa. In O. officinalis the percentage distances from the centromere to the hybridization sites were 20.00 +/- 5.40 and 22.12 +/- 3.44, the detection rates were 50.00% and 6.14%, but in O. sativa they were 0 and 0, 56.10% and 6.29% correspondingly. The results obtained from the BAC and RFLP clone were almost the same in the cultivated rice and O. officinalis. It was suggested that die marker RZ69 of the cultivated rice and its homologous sequence in O. officinalis were in the same BAC clone, the homologous sequence of Bph3 in O. officinalis should be located at the sites hybridized by both RZ69 and 38J9. Many signals on different chromosomes of O. officinalis were observed under no blocking with Cot-1 DNA, showing that the repetitive sequences were also homologous between O. sativa and O. officinalis. The identification of chromosome 4 of O. officinalis is based on comparative map with RG214 and BAC clone screened by RG214. The feasibility of comparative physical mapping performed between O. sativa and O. officinalis with rice BAC clones was discussed.
文摘背景:腰椎小关节炎是引起下腰痛的一个主要原因,目前主要依靠MRI进行初步定性诊断,但仍有一定漏诊、误诊的概率发生,因此MR T2^(*)mapping成像技术有望成为定量检查腰椎小关节炎软骨损伤的重要检测手段。目的:探讨MR T2^(*)mapping成像技术在定量分析腰椎小关节炎软骨损伤退变中的应用价值。方法:收集南京医科大学第四附属医院2020年4月至2022年3月门诊或住院合并下腰痛共110例患者,设为病例组;同时招募无症状志愿者80例,设为对照组。对所有纳入对象L1-S1的小关节行3.0 T MR扫描,获取T2^(*)mapping横断位图像和T2WI图像,分别对所有小关节软骨进行Weishaupt分级及T2^(*)值测量,收集数据并行统计学分析。不同小关节Weishaupt分级之间小关节软骨T2^(*)值比较采用单因素方差分析。结果与结论:①经统计分析发现,病例组腰椎小关节软骨T2^(*)值(17.6±1.5)ms明显较对照组(21.4±1.3)ms降低,差异有显著性意义(P<0.05);②在病例组中,随着腰椎小关节Weishaupt分级增加,小关节软骨T2^(*)值也呈逐渐下降趋势,且这种差异有显著性意义(P<0.05);③提示T2^(*)mapping能够较好地显示腰椎小关节软骨损伤的早期病理变化,腰椎小关节软骨的T2^(*)值能够定量评估腰椎小关节的软骨损伤程度;T2^(*)mapping成像技术能为影像学诊断腰椎小关节炎软骨早期损伤提供很好的理论依据,具有重要的临床应用价值。
基金This project is supported by National Natural Science Foundation ofChina(No.l9832020) and National Outstanding Youth Science Foundation ofChina(No.10125208).
文摘A physical value mapping （PVM） algorithm based on finite element mesh from the stamped part in stamping process to the product is presented, In order to improve the efficiency of the PVM algorithm, a search way from the mesh of the product to the mesh of the stamped part will be adopted. At the same time, the search process is divided into two steps： entire search （ES） and local search （LS）, which improve the searching efficiency. The searching area is enlarged to avoid missing projection elements in ES process. An arc-length method is introduced in LS process. The validity is confirmed by the results of the complex industry-forming product.
基金Supported by the NSF of China(Grant no.31471488)State Key Laboratory of Crop Biology(2017KF03)+3 种基金Shandong Province Key Technology Innovation Project(2014GJJS0201-1)Transgenic Special Item(2016ZX08002003)National Modern Agricultural Industry System Construction Project(CARS-03-1-8)The Scholars of Taishan Seed Industry Project(2014-2019)
文摘Wheat powdery mildew （Pro） is a major disease of wheat worldwide. During the past years, numerous studies have been published on molecular mapping of Pm resistance gene（s） in wheat. We summarized the relevant findings of 89 major re- sistance gene mapping studies and 25 quantitative trait loci （QTL） mapping studies. Major Pm resistance genes and QTLs were found on all wheat chromosomes, but the Pm resistance genes/QTLs were not randomly distributed on each chromosome of wheat. The summarized data showed that the A or B genome has more major Pm resistance genes than the D genome and chromosomes 1A, 2A, 2B, 5B, 5D, 6B, 7A and 7B harbor more major Pm resistance genes than the other chromosomes. For adult plant resistance （APR） genes/QTLs, B genome of wheat harbors more APR genes than A and D genomes, and chromo- somes 2A, 4A, 5A, 1B, 2B, 3B, 5B, 6B, 7B, 2D, 5D and 7D harbor more Pm resistance QTLs than the other chromosomes, suggesting that A genome except 1A, 3A and 6A, B genome except 4B, D genome except 1D, 3D, 4D, and 6D play an impor- tant role in wheat combating against powdery mildew. Furthermore, Pm resistance genes are derived from wheat and its rela- tives, which suggested that the resistance sources are diverse and Pm resistance genes are diverse and useful in combating against the powdery mildew isolates. In this review, four APR genes, Pm38/Lr34/Yr18/Sr57, Pm46/Lr67/Yr46/Sr55, Pm？/Lr27/Yr30/ SY2 and Pm39/Lr46/Yr29, are not only resistant to powdery mildew but also effective for rust diseases in the field, indicating that such genes are stable and useful in wheat breeding programmes. The summarized data also provide chromosome locations or linked markers for Pm resistance genes/QTLs. Markers linked to these genes can also be utilized to pyramid diverse Pm resis- tance genes/QTLs more efficiently by marker-assisted selection.
文摘The eastern Mediterranean is a tectonically complex region evolving in the long term located in the midst of the progressive Afro-Eurasian collision. Despite years of investigation, its geological-geophysical structure is not completely known. At the same time, the recent discovery of large gas deposits has attracted the attention of many researchers to this region. For instance, the latest U. S. Geological Survey estimates using conventional assessment methodology suggest that there are on the order of 1.7 billion barrels of recoverable oil and more than 4 trillion m3 of recoverable gas in the Levant Basin [1]. This highlights the need for analysis of the paleogeographical conditions that can yield deep paleotectonic criteria for oil and gas discovery in this region. For this purpose, isopach maps of the Middle-Upper Jurassic and Lower Cretaceous were generated from detailed examinations of numerous well sections and the most significant outcroppings in the eastern Mediterranean. The maps confirm an earlier model of continental accretion [2]. In particular, abrupt changes in the trend and thickness of the Early Mesozoic formations coincide with the terrane boundaries. These compiled isopach maps also pinpoint significant distinctions between the Arabian and Sinai plates on the one hand and the Syrian arc on the other. A new tectonic map of the eastern Mediterranean is presented that first of all integrates geophysical satellite-derived gravity and airborne magnetic fields, as well as tectonic-structural, paleogeographical and facial analyses. The results have clear implications for hydrocarbon prospecting in this region.
文摘Background:The Compendium of Physical Activities was published in 1993 to improve the comparability of energy expenditure values assigned to self-reported physical activity(PA)across studies.The original version was updated in 2000,and again in 2011,and has been widely used to support PA research,practice,and public health guidelines.Methods:This 2024 update was tailored for adults 19-59 years of age by removing data from those≥60 years.Using a systematic review and supplementary searches,we identified new activities and their associated measured metabolic equivalent(MET)values(using indirect calorimetry)published since 2011.We replaced estimated METs with measured values when possible.Results:We screened 32,173 abstracts and 1507 full-text papers and extracted 2356 PA energy expenditure values from 701 papers.We added303 new PAs and adjusted 176 existing MET values and descriptions to reflect the addition of new data and removal of METs for older adults.We added a Major Heading(Video Games).The 2024 Adult Compendium includes 1114 PAs(912 with measured and 202 with estimated values)across 22 Major Headings.Conclusion:This comprehensive update and refinement led to the creation of The 2024 Adult Compendium,which has utility across research,public health,education,and healthcare domains,as well as in the development of consumer health technologies.The new website with the complete lists of PAs and supporting resources is available at https://pacompendium.com.
文摘Background:Lifestyle plays an important role in preventing and managing gastroesophageal reflux disease(GERD).In response to the conflicting results in previous studies,we performed a systematic review and meta-analysis to investigate this association.Methods:Relevant studies published until January 2023 were retrieved from 6 databases,and the prevalence of symptomatic gastroesophageal reflux(GER)or GERD was determined from the original studies.A random effects model was employed to meta-analyze the association by computing the pooled relative risk(RR)with 95%confidence intervals(95%CIs).Furthermore,subgroup and dose-response analyses were performed to explore subgroup differences and the association between cumulative physical activity(PA)time and GERD.Results:This meta-analysis included 33 studies comprising 242,850 participants.A significant negative association was observed between PA and the prevalence of symptomatic GER(RR=0.74,95%CI:0.66-0.83;p<0.01)or GERD(RR=0.80,95%CI:0.76-0.84;p<0.01),suggesting that engaging in PA might confer a protective benefit against GERD.Subgroup analyses consistently indicated the presence of this association across nearly all subgroups,particularly among the older individuals(RR_(<40 years):RR_(≥40 years)=0.85:0.69,p<0.01)and smokers(RR_(smoker):RR_(non-smoker)=0.67:0.82,p=0.03).Furthermore,a dose-response analysis revealed that individuals who engaged in 150 min of PA per week had a 72.09%lower risk of developing GERD.Conclusion:Maintaining high levels of PA decreased the risk of GERD,particularly among older adults and smokers.Meeting the recommended PA level of 150 min per week may significantly decrease the prevalence of GERD.
