BACKGROUND Increasing numbers of total joint arthroplasties and consecutive revision surgery are associated with the risk of periprosthetic joint infections (PPJI). Treatment of PPJI is complex and associated with imm...BACKGROUND Increasing numbers of total joint arthroplasties and consecutive revision surgery are associated with the risk of periprosthetic joint infections (PPJI). Treatment of PPJI is complex and associated with immense socio-economic burden. One treatment aspect is parenteral antiinfective therapy, which usually requires an inpatient setting [Inpatient parenteral antibiotic therapy (IPAT)]. An alternative is outpatient parenteral treatment [Outpatient parenteral antibiotic therapy (OPAT)]. To conduct a health economic cost-benefit analysis of OPAT, a detailed cost analysis of IPAT and OPAT is required. So far, there is a lack of knowledge on the health economic effects of IPAT and OPAT for PPJI. AIM To review an economic comparison of IPAT and OPAT. METHODS A systematic literature review was performed through Medline following the PRISMA guidelines. RESULTS Of 619 identified studies, 174 included information of interest and 21 studies were included for quantitative analysis of OPAT and IPAT costs. Except for one study, all showed relevant cost savings for OPAT compared to IPAT. Costs for IPAT were between 1.10 to 17.34 times higher than those for OPAT. CONCLUSION There are only few reports on OPAT for PPJI. Detailed analyses to support economic or clinical guidelines are therefore limited. There is good clinical evidence supporting economic benefits of OPAT, but more high quality studies are needed for PPJI.展开更多
目的联合以问题为导向教学法(problem based learning,PBL)、以案例为基础教学法(case based learning,CBL)及督导式门诊教学方法对全科转岗培训医生教学,探讨一种高效的全科医生转岗培训教学模式。方法随机选取2021年10月—2022年10月...目的联合以问题为导向教学法(problem based learning,PBL)、以案例为基础教学法(case based learning,CBL)及督导式门诊教学方法对全科转岗培训医生教学,探讨一种高效的全科医生转岗培训教学模式。方法随机选取2021年10月—2022年10月在湖南省湘潭市中心医院全科医学科进行转岗培训的医生53名为研究对象,按照简单随机化方法分为两组,研究组(n=27名)实施PBL+CBL病房教学联合督导式门诊教学,对照组(n=26名)采取常规教学。比较两组理论考试成绩、体格检查站成绩、基本技能操作成绩、专科技能操作成绩、临床思维与决策成绩。结果培训后,研究组理论考试成绩、体格检查站成绩、基本技能操作成绩、专科数据技能操作成绩、临床思维与决策成绩、总分均高于对照组,差异有统计学意义(P<0.05)。结论PBL+CBL病房教学联合督导式门诊教学可明显提高全科转岗医生综合能力。展开更多
文摘BACKGROUND Increasing numbers of total joint arthroplasties and consecutive revision surgery are associated with the risk of periprosthetic joint infections (PPJI). Treatment of PPJI is complex and associated with immense socio-economic burden. One treatment aspect is parenteral antiinfective therapy, which usually requires an inpatient setting [Inpatient parenteral antibiotic therapy (IPAT)]. An alternative is outpatient parenteral treatment [Outpatient parenteral antibiotic therapy (OPAT)]. To conduct a health economic cost-benefit analysis of OPAT, a detailed cost analysis of IPAT and OPAT is required. So far, there is a lack of knowledge on the health economic effects of IPAT and OPAT for PPJI. AIM To review an economic comparison of IPAT and OPAT. METHODS A systematic literature review was performed through Medline following the PRISMA guidelines. RESULTS Of 619 identified studies, 174 included information of interest and 21 studies were included for quantitative analysis of OPAT and IPAT costs. Except for one study, all showed relevant cost savings for OPAT compared to IPAT. Costs for IPAT were between 1.10 to 17.34 times higher than those for OPAT. CONCLUSION There are only few reports on OPAT for PPJI. Detailed analyses to support economic or clinical guidelines are therefore limited. There is good clinical evidence supporting economic benefits of OPAT, but more high quality studies are needed for PPJI.
文摘目的联合以问题为导向教学法(problem based learning,PBL)、以案例为基础教学法(case based learning,CBL)及督导式门诊教学方法对全科转岗培训医生教学,探讨一种高效的全科医生转岗培训教学模式。方法随机选取2021年10月—2022年10月在湖南省湘潭市中心医院全科医学科进行转岗培训的医生53名为研究对象,按照简单随机化方法分为两组,研究组(n=27名)实施PBL+CBL病房教学联合督导式门诊教学,对照组(n=26名)采取常规教学。比较两组理论考试成绩、体格检查站成绩、基本技能操作成绩、专科技能操作成绩、临床思维与决策成绩。结果培训后,研究组理论考试成绩、体格检查站成绩、基本技能操作成绩、专科数据技能操作成绩、临床思维与决策成绩、总分均高于对照组,差异有统计学意义(P<0.05)。结论PBL+CBL病房教学联合督导式门诊教学可明显提高全科转岗医生综合能力。
