The methods for producing inorganic particles with a narrow particle size distribution, which are useful as chromatographic packing materials for high performance liquid chromatography（HPLC）, are provided. These met...The methods for producing inorganic particles with a narrow particle size distribution, which are useful as chromatographic packing materials for high performance liquid chromatography（HPLC）, are provided. These methods are based on improvements in the polymerization induced colloid aggregation（PICA） process described. These improved methods involved both synthesis of zirconium oxide colloid and sintering method. Colloid is an important factor in the PICA process. The reaction factors of the aqueous sol colloid of zirconium oxide are studied. We use sintering procedure to sinter zirconium oxide colloid, the average particle size is 5 μm. Owing to different sintering procdure, the average pore size is between 7.0 32 nm and the average surface area is between 4487 m 2/g. [WT5HZ]展开更多
目的建立基于红外光谱(FT-IR)、气相色谱-质谱(GC-MS)、高分辨质谱(high resolution mass spectrometer,HRMS)、核磁共振波谱(nuclear magnetic resonance spectroscopy,NMR)等多技术联合检验合成大麻素类新精神活性物质5F-MDMB-PICA的...目的建立基于红外光谱(FT-IR)、气相色谱-质谱(GC-MS)、高分辨质谱(high resolution mass spectrometer,HRMS)、核磁共振波谱(nuclear magnetic resonance spectroscopy,NMR)等多技术联合检验合成大麻素类新精神活性物质5F-MDMB-PICA的方法。方法粉末样品直接用FT-IR检测;粉末样品用甲醇溶解、烟丝样品用甲醇提取后采用GC-MS和高分辨质谱检测;粉末样品用氘代甲醇溶解后进行核磁共振氢谱(1H NMR)结构确证。结果GC-MS检测测得样品中主要组分的质谱特征离子(m/z)为232(基峰)、144、376、320、288、260、116、212,HRMS实测的精确质量数[M+H]+为377.22305,经数据库检索比对再结合数据分析,并经1H NMR确证,确定了该样品为5F-MDMB-PICA。而且,样品中主要组分的GC-MS保留时间和特征离子与5F-MDMB-PICA对照品一致。结论本研究建立的方法快速、简便、准确,可用于样品中5F-MDMB-PICA的检验,同时可为其他合成大麻素类新精神活性物质的检验提供方法参考。展开更多
文摘The methods for producing inorganic particles with a narrow particle size distribution, which are useful as chromatographic packing materials for high performance liquid chromatography（HPLC）, are provided. These methods are based on improvements in the polymerization induced colloid aggregation（PICA） process described. These improved methods involved both synthesis of zirconium oxide colloid and sintering method. Colloid is an important factor in the PICA process. The reaction factors of the aqueous sol colloid of zirconium oxide are studied. We use sintering procedure to sinter zirconium oxide colloid, the average particle size is 5 μm. Owing to different sintering procdure, the average pore size is between 7.0 32 nm and the average surface area is between 4487 m 2/g. [WT5HZ]
文摘目的建立基于红外光谱(FT-IR)、气相色谱-质谱(GC-MS)、高分辨质谱(high resolution mass spectrometer,HRMS)、核磁共振波谱(nuclear magnetic resonance spectroscopy,NMR)等多技术联合检验合成大麻素类新精神活性物质5F-MDMB-PICA的方法。方法粉末样品直接用FT-IR检测;粉末样品用甲醇溶解、烟丝样品用甲醇提取后采用GC-MS和高分辨质谱检测;粉末样品用氘代甲醇溶解后进行核磁共振氢谱(1H NMR)结构确证。结果GC-MS检测测得样品中主要组分的质谱特征离子(m/z)为232(基峰)、144、376、320、288、260、116、212,HRMS实测的精确质量数[M+H]+为377.22305,经数据库检索比对再结合数据分析,并经1H NMR确证,确定了该样品为5F-MDMB-PICA。而且,样品中主要组分的GC-MS保留时间和特征离子与5F-MDMB-PICA对照品一致。结论本研究建立的方法快速、简便、准确,可用于样品中5F-MDMB-PICA的检验,同时可为其他合成大麻素类新精神活性物质的检验提供方法参考。
