The relationships between 17α,20β dihydroxy 4 pregnene 3 one (17α,20β DP) and plasma IgM and total protein levels were investigated in rainbow trout, Oncorhynchus mykiss .IgM and total protein levels decre...The relationships between 17α,20β dihydroxy 4 pregnene 3 one (17α,20β DP) and plasma IgM and total protein levels were investigated in rainbow trout, Oncorhynchus mykiss .IgM and total protein levels decreased in both sexes of mature rainbow trout when 17α,20β DP levels increased during the spawning season,while the elevated 17α,20β DP suppressed IgM levels and reversibly enhanced total protein concentrations in immature trout.This represents the first report of the effect of 17α,20β DP on fish immunity.These data suggest that the increase of 17α,20β DP in spawning season may be related to infectious skin diseases.展开更多
Wheat （Triticum aestivum） seeds were treated with atmospheric pressure gliding arc discharge plasmas to investigate the effects on water absorption, seed germination rate, seedling growth and yield in wheat. The sur...Wheat （Triticum aestivum） seeds were treated with atmospheric pressure gliding arc discharge plasmas to investigate the effects on water absorption, seed germination rate, seedling growth and yield in wheat. The surface architectures and functionalities of the seeds were found to modify due to plasma treatments. 6 rain treatment was provided 95%-100% germination rate. For the treatment duration of 3 and 9 rain the growth activity, dry matter accumulation, leaves chlorophyll contents, longest spikes, number of spikes/spikelet and total soluble protein content in shoots were improved. The grain yield of wheat was increased ,--20% by 6 min treatment with H2O/O2 plasma with respect to control.展开更多
目的建立四川省遂宁地区表观健康成年人群血浆果糖胺(fructosamine,FMN)、果糖胺/总蛋白比值(fructosamine to total protein ratio,FMN/TP)及果糖胺/清蛋白比值(fructosamine to albumin ratio,FMN/ALB)的参考区间。方法选取2017年1～1...目的建立四川省遂宁地区表观健康成年人群血浆果糖胺(fructosamine,FMN)、果糖胺/总蛋白比值(fructosamine to total protein ratio,FMN/TP)及果糖胺/清蛋白比值(fructosamine to albumin ratio,FMN/ALB)的参考区间。方法选取2017年1～12月遂宁市中心医院健康管理中心14 639例20～79岁的表观健康成年人作为研究对象,其中男性4 811例,女性9 828例,通过问卷调查、体格检查、超声及实验室检查排除呼吸系统、血液系统、内分泌系统、炎症和肿瘤等疾病,检测其血浆FMN、总蛋白(total protein,TP)和清蛋白(albumin,ALB)的浓度并计算该人群FMN/TP及FMN/ALB的浓度水平。根据性别和年龄将研究对象分组(男女各6组:20～29岁组,30～39岁组,40～49岁组,50～59岁组,60～69岁组和70～79岁组),对各组检测结果进行统计学分析,浓度水平差异无统计学意义的各组数据进行合并后,呈正态分布则以均值±1.96标准差■建立该地区表观健康人群血浆中FMN,FMN/TP及FMN/ALB的参考区间;呈偏态分布以百分位数法(P_(2.5)～P_(97.5))建立其参考区间。结果男性血浆FMN,FMN/TP及FMN/ALB浓度水平依次为1.7(1.6～1.8)mmol/L,22.0(20.7～23.5)μmol/g和37.1(34.5～39.8)μmol/g;女性则依次为1.7(1.6～1.8)mmol/L,22.4(21.1～23.9)μmol/g和38.5(36.2～41.2)μmol/g。男性和女性血浆FMN,FMN/TP及FMN/ALB浓度水平均呈偏态分布(P<0.05),且两组间比较差异均具有统计学意义(P<0.01)。进一步分析,男性和女性各年龄组血浆FMN,FMN/TP及FMN/ALB浓度水平的中位数与其总体区间中位数的差异均<25%,故不建议按年龄段分组建立参考区间,可仅按性别分组建立其参考区间。FMN的参考区间:男性为1.4～2.0 mmol/L,女性为1.5～2.0 mmol/L;FMN/TP的参考区间:男性为18.2～26.4μmol/g,女性为18.9～26.8μmol/g;FMN/ALB的参考区间:男性为30.4～46.1μmol/g,女性为32.1～46.9μmol/g。结论初步建立了遂宁地区20～79岁表观健康人群血浆FMN,FMN/TP及FMN/ALB的参考区间,为临床应用其作为糖尿病患者的诊断及疗效评估指标提供依据。展开更多
AIM:To investigate the risk of exudative retinal detachment(ERD)morbidity in patients with pregnancyinduced hypertension(PIH)by using the logistic regression combined with the receiver operating characteristic(ROC)cur...AIM:To investigate the risk of exudative retinal detachment(ERD)morbidity in patients with pregnancyinduced hypertension(PIH)by using the logistic regression combined with the receiver operating characteristic(ROC)curve.METHODS:A total of 46 patients with ERD and 142 patients with non-ERD were diagnosed as PIH from January 2017 to February 2020.A retrospective comparison of the clinical manifestations and laboratory tests were conducted.The risk of ERD morbidity with PIH was predicted by using logistic regression combined with an ROC curve model.RESULTS:There was no significant difference in age and body mass index between the two groups before pregnancy(P>0.05).However,significant differences were found in gestational weeks,duration of hypertension,maximum and minimum systolic and diastolic blood pressure(BP),and plasma total protein(PTP)concentration between the two groups(P<0.05).Binary logistic regression analysis showed that the maximum systolic BP(OR=1.050,95%CI:1.016-1.085)and PTP concentration(OR=0.764,95%CI:0.702-0.832)were independent prediction risks of ERD in PIH.The sensitivities of maximum systolic BP,PTP concentration and combined diagnosis were 0.717,0.870,and 0.870,respectively;the specificities were 0.617,0.837,and 0.908,respectively;the area under the curve(AUC)was 0.707(95%CI:0.622-0.792),0.917(95%CI:0.868-0.967),and 0.933(95%CI:0.890-0.975),respectively;the AUC of combined diagnosis was higher than that of single diagnosis(P<0.01).CONCLUSION:Logistic regression and ROC curve model combined with maximum systolic BP and PTP can improve the early identification of high-risk PIH patients in the hospital.展开更多
目的:探究心房颤动患者血清总胆汁酸(total bile acid,TBA)、超敏C反应蛋白(hypersensitive C reactive protein,hs-CRP)、血浆脑钠肽(Brain Natriuretic Peptide,BNP)水平变化及与心率变异性(heart rate variability,HRV)的相关性分析...目的:探究心房颤动患者血清总胆汁酸(total bile acid,TBA)、超敏C反应蛋白(hypersensitive C reactive protein,hs-CRP)、血浆脑钠肽(Brain Natriuretic Peptide,BNP)水平变化及与心率变异性(heart rate variability,HRV)的相关性分析。方法:应用回顾性方法选择并分析2017年3月至2019年6月来本院心内科就诊的217例心房颤动患者作为研究对象,并另选100名同期体检健康患者作为对照组,两组患者均进行24h心电监护,检测并比较两组患者的血清TBA、hs-CRP、BNP水平及HRV[24h所有窦性心搏间期NN标准差(NN standard deviation,SDNN);全程相邻NN间期差值的均方根(RMS of NN interval difference,RMSSD);全程记录中每5minNN间期平均值的标准差(NN standard deviation of mean of interval,SDANN);超过50ms的个数占总窦性心搏数的百分率(As a percentage of total sinusoids,the number of ms over 50,PNN50)]。结果:比较结果显示,研究组的TBA、hs-CRP、BNP高于对照组,SDNN、RMSSD、SDANN、PNN50低于对照组,差异有统计学意义(P<0.05);相关性分析结果显示,TBA与SDNN、RMSSD、SDANN、PNN50呈正相(r=0.469、0.474、0.447、0.418,P<0.05);hs-CRP与SDNN、RMSSD、SDANN、PNN50呈正相(r=0.560、0.595、0.600、0.582,P<0.05);BNP与SDNN、RMSSD、SDANN、PNN50呈正相(r=0.566、0.634、0.624、0.598,P<0.05)。结论:心房颤动患者血清TBA、hs-CRP、BNP水平均上升,且血清TBA、hs-CRP、BNP水平与HRV呈正相关。展开更多
文摘The relationships between 17α,20β dihydroxy 4 pregnene 3 one (17α,20β DP) and plasma IgM and total protein levels were investigated in rainbow trout, Oncorhynchus mykiss .IgM and total protein levels decreased in both sexes of mature rainbow trout when 17α,20β DP levels increased during the spawning season,while the elevated 17α,20β DP suppressed IgM levels and reversibly enhanced total protein concentrations in immature trout.This represents the first report of the effect of 17α,20β DP on fish immunity.These data suggest that the increase of 17α,20β DP in spawning season may be related to infectious skin diseases.
基金Partial financial support has been provided by the Ministry of Science and Technology, Republic of Bangladesh: 39.00.0000.09.06.79.2017/2/98ESBangladesh Council for Scientific and Industrial Research (BCSIR) for providing Professor Abdullah Al-Muti Sharfuddin fellowship
文摘Wheat （Triticum aestivum） seeds were treated with atmospheric pressure gliding arc discharge plasmas to investigate the effects on water absorption, seed germination rate, seedling growth and yield in wheat. The surface architectures and functionalities of the seeds were found to modify due to plasma treatments. 6 rain treatment was provided 95%-100% germination rate. For the treatment duration of 3 and 9 rain the growth activity, dry matter accumulation, leaves chlorophyll contents, longest spikes, number of spikes/spikelet and total soluble protein content in shoots were improved. The grain yield of wheat was increased ,--20% by 6 min treatment with H2O/O2 plasma with respect to control.
文摘目的建立四川省遂宁地区表观健康成年人群血浆果糖胺(fructosamine,FMN)、果糖胺/总蛋白比值(fructosamine to total protein ratio,FMN/TP)及果糖胺/清蛋白比值(fructosamine to albumin ratio,FMN/ALB)的参考区间。方法选取2017年1～12月遂宁市中心医院健康管理中心14 639例20～79岁的表观健康成年人作为研究对象,其中男性4 811例,女性9 828例,通过问卷调查、体格检查、超声及实验室检查排除呼吸系统、血液系统、内分泌系统、炎症和肿瘤等疾病,检测其血浆FMN、总蛋白(total protein,TP)和清蛋白(albumin,ALB)的浓度并计算该人群FMN/TP及FMN/ALB的浓度水平。根据性别和年龄将研究对象分组(男女各6组:20～29岁组,30～39岁组,40～49岁组,50～59岁组,60～69岁组和70～79岁组),对各组检测结果进行统计学分析,浓度水平差异无统计学意义的各组数据进行合并后,呈正态分布则以均值±1.96标准差■建立该地区表观健康人群血浆中FMN,FMN/TP及FMN/ALB的参考区间;呈偏态分布以百分位数法(P_(2.5)～P_(97.5))建立其参考区间。结果男性血浆FMN,FMN/TP及FMN/ALB浓度水平依次为1.7(1.6～1.8)mmol/L,22.0(20.7～23.5)μmol/g和37.1(34.5～39.8)μmol/g;女性则依次为1.7(1.6～1.8)mmol/L,22.4(21.1～23.9)μmol/g和38.5(36.2～41.2)μmol/g。男性和女性血浆FMN,FMN/TP及FMN/ALB浓度水平均呈偏态分布(P<0.05),且两组间比较差异均具有统计学意义(P<0.01)。进一步分析,男性和女性各年龄组血浆FMN,FMN/TP及FMN/ALB浓度水平的中位数与其总体区间中位数的差异均<25%,故不建议按年龄段分组建立参考区间,可仅按性别分组建立其参考区间。FMN的参考区间:男性为1.4～2.0 mmol/L,女性为1.5～2.0 mmol/L;FMN/TP的参考区间:男性为18.2～26.4μmol/g,女性为18.9～26.8μmol/g;FMN/ALB的参考区间:男性为30.4～46.1μmol/g,女性为32.1～46.9μmol/g。结论初步建立了遂宁地区20～79岁表观健康人群血浆FMN,FMN/TP及FMN/ALB的参考区间,为临床应用其作为糖尿病患者的诊断及疗效评估指标提供依据。
文摘AIM:To investigate the risk of exudative retinal detachment(ERD)morbidity in patients with pregnancyinduced hypertension(PIH)by using the logistic regression combined with the receiver operating characteristic(ROC)curve.METHODS:A total of 46 patients with ERD and 142 patients with non-ERD were diagnosed as PIH from January 2017 to February 2020.A retrospective comparison of the clinical manifestations and laboratory tests were conducted.The risk of ERD morbidity with PIH was predicted by using logistic regression combined with an ROC curve model.RESULTS:There was no significant difference in age and body mass index between the two groups before pregnancy(P>0.05).However,significant differences were found in gestational weeks,duration of hypertension,maximum and minimum systolic and diastolic blood pressure(BP),and plasma total protein(PTP)concentration between the two groups(P<0.05).Binary logistic regression analysis showed that the maximum systolic BP(OR=1.050,95%CI:1.016-1.085)and PTP concentration(OR=0.764,95%CI:0.702-0.832)were independent prediction risks of ERD in PIH.The sensitivities of maximum systolic BP,PTP concentration and combined diagnosis were 0.717,0.870,and 0.870,respectively;the specificities were 0.617,0.837,and 0.908,respectively;the area under the curve(AUC)was 0.707(95%CI:0.622-0.792),0.917(95%CI:0.868-0.967),and 0.933(95%CI:0.890-0.975),respectively;the AUC of combined diagnosis was higher than that of single diagnosis(P<0.01).CONCLUSION:Logistic regression and ROC curve model combined with maximum systolic BP and PTP can improve the early identification of high-risk PIH patients in the hospital.
文摘目的:探究心房颤动患者血清总胆汁酸(total bile acid,TBA)、超敏C反应蛋白(hypersensitive C reactive protein,hs-CRP)、血浆脑钠肽(Brain Natriuretic Peptide,BNP)水平变化及与心率变异性(heart rate variability,HRV)的相关性分析。方法:应用回顾性方法选择并分析2017年3月至2019年6月来本院心内科就诊的217例心房颤动患者作为研究对象,并另选100名同期体检健康患者作为对照组,两组患者均进行24h心电监护,检测并比较两组患者的血清TBA、hs-CRP、BNP水平及HRV[24h所有窦性心搏间期NN标准差(NN standard deviation,SDNN);全程相邻NN间期差值的均方根(RMS of NN interval difference,RMSSD);全程记录中每5minNN间期平均值的标准差(NN standard deviation of mean of interval,SDANN);超过50ms的个数占总窦性心搏数的百分率(As a percentage of total sinusoids,the number of ms over 50,PNN50)]。结果:比较结果显示,研究组的TBA、hs-CRP、BNP高于对照组,SDNN、RMSSD、SDANN、PNN50低于对照组,差异有统计学意义(P<0.05);相关性分析结果显示,TBA与SDNN、RMSSD、SDANN、PNN50呈正相(r=0.469、0.474、0.447、0.418,P<0.05);hs-CRP与SDNN、RMSSD、SDANN、PNN50呈正相(r=0.560、0.595、0.600、0.582,P<0.05);BNP与SDNN、RMSSD、SDANN、PNN50呈正相(r=0.566、0.634、0.624、0.598,P<0.05)。结论:心房颤动患者血清TBA、hs-CRP、BNP水平均上升,且血清TBA、hs-CRP、BNP水平与HRV呈正相关。
