BACKGROUND Pulmonary tumorlets are nodular hyperplastic neuroendocrine cells(NECs)that extend beyond the basement membrane.They often coexist with other lung diseases such as fibrosis and bronchiectasis,but rarely acc...BACKGROUND Pulmonary tumorlets are nodular hyperplastic neuroendocrine cells(NECs)that extend beyond the basement membrane.They often coexist with other lung diseases such as fibrosis and bronchiectasis,but rarely accompanied by pulmonary sclerosing pneumocytoma(PSP),which has not been reported in the literature.CASE SUMMARY A 54-year-old woman was admitted to the hospital because she had symptoms of bloody sputum for more than 4 mo and hemoptysis for 1 wk.Computed tomography images showed atrophy accompanied by infections in the middle lobe of her right lung.Moreover,numerous nodules were identified in the middle lobe of the right lung.The patient underwent thoracoscopic pneumonectomy of the middle lobe of the right lung,and the resected mass was pathologically confirmed to have bronchiectasis,multifocal NEC hyperplasia accompanied by tumorlet,and PSP.CONCLUSION Our report presents a rare clinical case of bronchiectasis complicated with multifocal NEC hyperplasia,tumorlet,and PSP.展开更多
Objective:To investigate the manifestations of pulmonary sclerosing pneumocytoma by multi-slice spiral CT (MSCT) and ^18F-FDG PET/CT in order to improve the accuracy of preoperative diagnosis. Methods:42 cases of PSP ...Objective:To investigate the manifestations of pulmonary sclerosing pneumocytoma by multi-slice spiral CT (MSCT) and ^18F-FDG PET/CT in order to improve the accuracy of preoperative diagnosis. Methods:42 cases of PSP confirmed by pathology after operation were retrospectively analyzed. The distribution, size, shape, special signs and metabolic characteristics of lesions were observed. The relationship between the maximum diameter of lesions and clinical symptoms and the correlation between the maximum diameter of lesions and the maximum standardized uptake value (SUVmax) were analyzed. Results:MSCT plain scan was performed in 36 cases, enhanced in 29 cases, MSCT observed vessel marginal sign in 21 cases, air crescent sign in 9 cases, halo sign in 7 cases, calcification in 20 cases, transfissure sign in 6 cases, pleural plain scan in 23 cases;mean value of CT plain scan (36.50±21.65) HU, mean arterial phase of enhanced CT (73.13±37.22) HU, venous phase (74.78±18.36) HU;There was no significant difference in the maximum diameter of lesions between the symptomatic group and the asymptomatic group (P=0.283);^18F-FDG PET/CT in 16 cases, showed 1 case of low uptake (6.25%), 6 cases of moderate uptake (37.50%), 9 cases of high uptake (56.25%) and 3 cases of hilar and mediastinal lymph node hypermetabolism. There was no significant difference between the size of typical lesions and SUVmax(P=0.212);There was no significant correlation between the size of atypical lesions and SUVmax (P=0.253), and between the size of typical and atypical lesions and SUVmax (P=0.066). There were 8 cases of PSP diagnosed correctly before operation, with an accuracy of 19.05%, 2 cases of hamartoma, 3 cases of inflammatory pseudotumors, 3 cases of tuberculoma, 3 cases of metastasis and 10 cases of malignant tumors. Conclusion:The metabolic characteristics of PSP lesions in MSCT such as "blood vessel marginal sign", "air crescent sign", "halo sign", "transfissure sign", "calcification", "pleura sticking" and 18F-FDG PET/CT can show malignant tumors, which provide important basis for the diagnosis of PSP.展开更多
文摘BACKGROUND Pulmonary tumorlets are nodular hyperplastic neuroendocrine cells(NECs)that extend beyond the basement membrane.They often coexist with other lung diseases such as fibrosis and bronchiectasis,but rarely accompanied by pulmonary sclerosing pneumocytoma(PSP),which has not been reported in the literature.CASE SUMMARY A 54-year-old woman was admitted to the hospital because she had symptoms of bloody sputum for more than 4 mo and hemoptysis for 1 wk.Computed tomography images showed atrophy accompanied by infections in the middle lobe of her right lung.Moreover,numerous nodules were identified in the middle lobe of the right lung.The patient underwent thoracoscopic pneumonectomy of the middle lobe of the right lung,and the resected mass was pathologically confirmed to have bronchiectasis,multifocal NEC hyperplasia accompanied by tumorlet,and PSP.CONCLUSION Our report presents a rare clinical case of bronchiectasis complicated with multifocal NEC hyperplasia,tumorlet,and PSP.
基金Shaanxi provincial health and family planning research fund project(No.2016D010).
文摘Objective:To investigate the manifestations of pulmonary sclerosing pneumocytoma by multi-slice spiral CT (MSCT) and ^18F-FDG PET/CT in order to improve the accuracy of preoperative diagnosis. Methods:42 cases of PSP confirmed by pathology after operation were retrospectively analyzed. The distribution, size, shape, special signs and metabolic characteristics of lesions were observed. The relationship between the maximum diameter of lesions and clinical symptoms and the correlation between the maximum diameter of lesions and the maximum standardized uptake value (SUVmax) were analyzed. Results:MSCT plain scan was performed in 36 cases, enhanced in 29 cases, MSCT observed vessel marginal sign in 21 cases, air crescent sign in 9 cases, halo sign in 7 cases, calcification in 20 cases, transfissure sign in 6 cases, pleural plain scan in 23 cases;mean value of CT plain scan (36.50±21.65) HU, mean arterial phase of enhanced CT (73.13±37.22) HU, venous phase (74.78±18.36) HU;There was no significant difference in the maximum diameter of lesions between the symptomatic group and the asymptomatic group (P=0.283);^18F-FDG PET/CT in 16 cases, showed 1 case of low uptake (6.25%), 6 cases of moderate uptake (37.50%), 9 cases of high uptake (56.25%) and 3 cases of hilar and mediastinal lymph node hypermetabolism. There was no significant difference between the size of typical lesions and SUVmax(P=0.212);There was no significant correlation between the size of atypical lesions and SUVmax (P=0.253), and between the size of typical and atypical lesions and SUVmax (P=0.066). There were 8 cases of PSP diagnosed correctly before operation, with an accuracy of 19.05%, 2 cases of hamartoma, 3 cases of inflammatory pseudotumors, 3 cases of tuberculoma, 3 cases of metastasis and 10 cases of malignant tumors. Conclusion:The metabolic characteristics of PSP lesions in MSCT such as "blood vessel marginal sign", "air crescent sign", "halo sign", "transfissure sign", "calcification", "pleura sticking" and 18F-FDG PET/CT can show malignant tumors, which provide important basis for the diagnosis of PSP.
