Poly （3, 4-ethylenedioxythiophene） （PEDOT）, together with its dopes, such as poly （styrene sulfonate） （PSS）, has been acknowledged to have a wide range of biomedical applications as an important conducting pol...Poly （3, 4-ethylenedioxythiophene） （PEDOT）, together with its dopes, such as poly （styrene sulfonate） （PSS）, has been acknowledged to have a wide range of biomedical applications as an important conducting polymer. In this study, gelatin can be polymerized into PEDOT/PSS polymers on indium tin oxide （ITO）-coated glass. PEDOT/PSS/gelatin layer on ITO-coated glass significantly decreases electrochemical impedance spectroscopy （EIS） and increases charge delivery capacity relative to the gelatin layer and bare ITO- coated glass, comparable to the PEDOT/PSS layer on ITO-coated glass. PEDOT/PSS/gelatin layer on ITO- coated glass enhances pheochromocytoma （PC 12） cell affinity, possesses a high biocompatibility and promotes PC 12 cell growth by delivery of electrical stimulation. These results suggest that gelatin can be incorporated into the PEDOT/PSS polymers through electrochemical polymerization and the PEDOT/PSS/gelatin layer on ITO-coated glass possesses high electrochemical and biological activities.展开更多
In this work,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)coated silver telluride(PCeAg2Te)nanorods were prepared by a wet-chemical method using the PEDOT:PSS coated tellurium(PCeTe)nanorods as th...In this work,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)coated silver telluride(PCeAg2Te)nanorods were prepared by a wet-chemical method using the PEDOT:PSS coated tellurium(PCeTe)nanorods as the templates.Flexible PCeAg2Te nanocomposite film on polyethersulfone(PES)substrate was prepared through vacuum filtration followed by mechanical pressing process.An optimal PCeAg2Te nanocomposite film showed a maximum power factor of 143.3 mW/mK^(2) at room temperature and 221.7 μW/mK^(2 ) at 373 K.The electrical conductivity of the PCeAg2Te composite film decreased by3.3%after bending for 1000 times around a rod with a radius of 5 mm.An eight-leg thermoelectric generator assembled with the optimal PCeAg2Te nanocomposite film generated a maximum output power and output density of 209.4 nW and 141.5 mW/cm^(2) at a temperature gradient of 30.3 K.This work provides a facile method to prepare thermoelectric materials for flexible thermoelectric generators.展开更多
A multi-technique approach to prove the preparation of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril)pseudorotaxanes(PEDOT∙CB7-PPs)is reported.Molecular docking simulation and matrix-assisted laser desorption/ioniza...A multi-technique approach to prove the preparation of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril)pseudorotaxanes(PEDOT∙CB7-PPs)is reported.Molecular docking simulation and matrix-assisted laser desorption/ionization mass spectrometry(MALDI MS)validate the complexation ability of the CB7 molecule towards 3,4-ethylenedioxythiophene(EDOT),which leads to the EDOT∙CB7 inclusion complex.Oxidative polymerization of EDOT∙CB7 enabled the synthesis of PEDOT∙CB7-PPs.The water-soluble part of PEDOT∙CB7-PPs was selected,freeze-dried,and chemically characterized.Furthermore,dynamic light scattering(DLS)has been used to study the particle size and z-potential(ZP-ζ)of PEDOT∙CB7-PPs.The ZP-ζvalue(35 mV)evidenced that the PEDOT∙CB7-PPs formed stable water dispersion.By combining the emerging nanopore resistive pulse sensing technique(Np-RPS)and computational modeling,we identified strong interactions of PEDOT∙CB7-PPs with the aerolysin(Ael)nanopore.PEDOT∙CB7-PPs behave as positive charged species,and thus trans negative bias promotes its interactions with the Ael nanopore.The computational modeling results are fully consistent with the Np-RPS detection,which also reveals strong interactions between PEDOT∙CB7-PPs and the Ael nanopore.With this study,we hope to provide new insights and a better understanding of the interactions between supramolecular complexes based on CB7 and biological entities,which is instrumental for future applications in the field of nanobiotechnology.展开更多
An increase of work function （0.3 eV） is achieved by irradiating poly（3,4-ethylenedioxythiophene）：poly（styrene sul- fonate） （PEDOT：PSS） film in vacuum with 254-nm ultraviolet （UV） light. The mechanism for ...An increase of work function （0.3 eV） is achieved by irradiating poly（3,4-ethylenedioxythiophene）：poly（styrene sul- fonate） （PEDOT：PSS） film in vacuum with 254-nm ultraviolet （UV） light. The mechanism for such an improvement is investigated by photoelectron yield spectroscopy, X-ray photo electron energy spectrum, and field emission technique. Sur- face oxidation and composition change are found as the reasons for work function increase. The UV-treated PEDOT：PSS film is used as the hole injection layer in a hole-only device. Hole injection is improved by UV-treated PEDOT：PSS film without baring the enlargement of film resistance. Our result demonstrates that UV treatment is more suitable for modifying the injection barrier than UV ozone exposure.展开更多
Recently, increasing attention has been paid to magneto-conjugated polymer core-shell nanoparticles （NPs） as theranostic platforms. However, the utilization of surfactants and extra oxidizing agents with potential t...Recently, increasing attention has been paid to magneto-conjugated polymer core-shell nanoparticles （NPs） as theranostic platforms. However, the utilization of surfactants and extra oxidizing agents with potential toxicity in synthesis, the lack of general methods for the controlled synthesis of various kinds of magnetic NP （MNP）@conjugated polymer NPs, and the difficulty of obtaining balanced magneto-optical properties have greatly limited the applications of magneto-conjugated polymers in theranostics. We developed an in situ surface polymerization method free of extra surfactants and oxidizing agents to synthesize MNP@polypyrrole （PPy） NPs with balanced, prominent magneto-optical properties. MNP@PPy NPs with an adjustable size, different shapes, and a controlled shell thickness were obtained using this method. The method was extended to synthesize other MNP-conjugated polymer core-shell NPs, such as MNP@polyaniline and MNP@poly（3,4-ethylenedioxythiophene）：poly（4- styrenesulfonate） （PEDOT：PSS）. We discuss the formation mechanism of the proposed method according to our experimental results. Finally, using the optical and magnetic properties of the obtained MNP@PEDOT：PSS NPs, in vivo multimodal imaging-guided hyperthermia was induced in mice, achieving an excellent tumor-ablation therapeutic effect. Our work is beneficial for extending the application of MNP-conjugated polymer core-shell NPs in the biomedical field.展开更多
In this paper, we fabricated an organic thermo- electric （TE） device with modified [6,6]-phenyl-C61- butyric acid methyl ester （PCBM） and poly（3,4-ethylene- dioxythiophene） polystyrene sulfonate （PEDOT：PSS）; ...In this paper, we fabricated an organic thermo- electric （TE） device with modified [6,6]-phenyl-C61- butyric acid methyl ester （PCBM） and poly（3,4-ethylene- dioxythiophene） polystyrene sulfonate （PEDOT：PSS）; the device showed good stability in air condition. For n-leg, PCBM were doped with acridine orange base （3,6-bis （dimethylamino）acridine） （AOB） and 1,3-dimethyl-2,3- dihydro- 1H-benzoimidazole （N-DMBI）. Co-doped PCBM utilizes synergistic effects of AOB and N-DMBI, resulting in excellent electrical conductivity and Seebeck coefficient values reaching 2 S/cm and -500 μV/K, respectively, at room temperature with dopant molar ratio of 0.11. P-type leg used modified PEDOT：PSS. Based on modified PCBM and PEDOT：PSS materials, we fabricated a TE module device with 48 p-type and n-type thermocouple and tested their output voltage, short current, and power. Output voltage measured -0.82 V, and generated power reached almost 945 μW with 75 K temperature gradient at 453 K hot-side temperature. These promising results showed potential of modified PEDOT and PCBM as TE materials for application in device optimization.展开更多
The issue of sensitivity attenuation in high-pressure region has been a persistent concern for pressure-sensitive electronic skins.In order to tackle such trade-off between sensitivity and linear range,herein,a hybrid...The issue of sensitivity attenuation in high-pressure region has been a persistent concern for pressure-sensitive electronic skins.In order to tackle such trade-off between sensitivity and linear range,herein,a hybrid piezoresistive-supercapacitive(HRSC)strategy is proposed via introducing a piezoresistive porous aerogel layer between the charge collecting electrodes and iontronic films of the pressure sensors.Surprisingly,the HRSC-induced impedance regulation and supercapacitive behavior contribute to significant mitigation in sensitivity attenuation,achieving high sensitivity across wide linear range(44.58 kPa^(−1)from 0 to 3 kPa and 23.6 kPa^(−1)from 3 to 12 kPa).The HRSC pressure sensor exhibits a low detection limit of 1 Pa,fast responsiveness(~130 ms),and excellent cycling stability,allowing to detect tiny pressure of air flow,finger bending,and human respiration.Meanwhile,the HRSC sensor exhibits exceptional perception capabilities for proximity and temperature,broadening its application scenarios in prosthetic perception and electronic skin.The proposed HRSC strategy may boost the ongoing research on structural design of high-performance and multimodal electronic sensors.展开更多
Recently,stretchable and wearable health monitoring equipment has greatly improved human’s daily life,which sets higher demands for portable power source in stretchability,sustainability,and biocompatibility.In this ...Recently,stretchable and wearable health monitoring equipment has greatly improved human’s daily life,which sets higher demands for portable power source in stretchability,sustainability,and biocompatibility.In this work,we proposed a stretchable triboelectric nanogenerator(TENG)based on stretchable poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)/porous carbon hybrid for oxyhemoglobin saturation(SpO2)monitoring.To combine advantages of carbon material for its high conductivity and organic electrode for its high stretchability,we spin-coated a solution of PEDOT:PSS/porous carbon onto a plasma-treated pre-stretched Ecoflex film to fabricate a stretchable electrode with rough surface.Due to its roughness and high potential difference with the dielectric material,the stretchable-electrode-based TENG exhibited better performance compared to the pristine TENG based on carbon or PEDOT:PSS material.The output voltage and current reached up to 51.5 V and 13.2μA as the carbon concentration increased.More importantly,the performance further increased under large strain(100%)which is suitable for wearable systems.Finally,the device demonstrated its application potential for powering a flexible blood oxygen monitor.This simple and cost-effective method can enhance the stretchability and stability of organic/inorganic electrode-based TENG,which paves the development of high-performance stretchable TENG.展开更多
基金Funded by National Natural Science Foundation of China(Nos.11179015,51173108)Innovation Program of Shanghai Municipal Education Commission(No.12ZZ143)
文摘Poly （3, 4-ethylenedioxythiophene） （PEDOT）, together with its dopes, such as poly （styrene sulfonate） （PSS）, has been acknowledged to have a wide range of biomedical applications as an important conducting polymer. In this study, gelatin can be polymerized into PEDOT/PSS polymers on indium tin oxide （ITO）-coated glass. PEDOT/PSS/gelatin layer on ITO-coated glass significantly decreases electrochemical impedance spectroscopy （EIS） and increases charge delivery capacity relative to the gelatin layer and bare ITO- coated glass, comparable to the PEDOT/PSS layer on ITO-coated glass. PEDOT/PSS/gelatin layer on ITO- coated glass enhances pheochromocytoma （PC 12） cell affinity, possesses a high biocompatibility and promotes PC 12 cell growth by delivery of electrical stimulation. These results suggest that gelatin can be incorporated into the PEDOT/PSS polymers through electrochemical polymerization and the PEDOT/PSS/gelatin layer on ITO-coated glass possesses high electrochemical and biological activities.
基金supported by the National Natural Science Foundation of China(51972234,51632010)the National Key Research&Development Project of China(Grant No.2018YFE0111500)。
文摘In this work,poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)coated silver telluride(PCeAg2Te)nanorods were prepared by a wet-chemical method using the PEDOT:PSS coated tellurium(PCeTe)nanorods as the templates.Flexible PCeAg2Te nanocomposite film on polyethersulfone(PES)substrate was prepared through vacuum filtration followed by mechanical pressing process.An optimal PCeAg2Te nanocomposite film showed a maximum power factor of 143.3 mW/mK^(2) at room temperature and 221.7 μW/mK^(2 ) at 373 K.The electrical conductivity of the PCeAg2Te composite film decreased by3.3%after bending for 1000 times around a rod with a radius of 5 mm.An eight-leg thermoelectric generator assembled with the optimal PCeAg2Te nanocomposite film generated a maximum output power and output density of 209.4 nW and 141.5 mW/cm^(2) at a temperature gradient of 30.3 K.This work provides a facile method to prepare thermoelectric materials for flexible thermoelectric generators.
基金supported by a grant of the Ministry of Research,Innovation and Digitization,CNCS–UEFISCDI,project number PN-III-P4-PCE-2021-0906within PNCDI III and the Institute desÉtudes Avancées(IEA)of Cergy-Pontoise University(Project INEX“Pi-ROT”#73).
文摘A multi-technique approach to prove the preparation of poly(3,4-ethylenedioxythiophene/cucurbit[7]uril)pseudorotaxanes(PEDOT∙CB7-PPs)is reported.Molecular docking simulation and matrix-assisted laser desorption/ionization mass spectrometry(MALDI MS)validate the complexation ability of the CB7 molecule towards 3,4-ethylenedioxythiophene(EDOT),which leads to the EDOT∙CB7 inclusion complex.Oxidative polymerization of EDOT∙CB7 enabled the synthesis of PEDOT∙CB7-PPs.The water-soluble part of PEDOT∙CB7-PPs was selected,freeze-dried,and chemically characterized.Furthermore,dynamic light scattering(DLS)has been used to study the particle size and z-potential(ZP-ζ)of PEDOT∙CB7-PPs.The ZP-ζvalue(35 mV)evidenced that the PEDOT∙CB7-PPs formed stable water dispersion.By combining the emerging nanopore resistive pulse sensing technique(Np-RPS)and computational modeling,we identified strong interactions of PEDOT∙CB7-PPs with the aerolysin(Ael)nanopore.PEDOT∙CB7-PPs behave as positive charged species,and thus trans negative bias promotes its interactions with the Ael nanopore.The computational modeling results are fully consistent with the Np-RPS detection,which also reveals strong interactions between PEDOT∙CB7-PPs and the Ael nanopore.With this study,we hope to provide new insights and a better understanding of the interactions between supramolecular complexes based on CB7 and biological entities,which is instrumental for future applications in the field of nanobiotechnology.
基金Project supported by the National Natural Science Foundation of China(Grant Nos.61076057,61376059,61171023,and 91221202,)the National Basic Research Program of China(Grant Nos.2012CB932701 and 2011CB933001)
文摘An increase of work function （0.3 eV） is achieved by irradiating poly（3,4-ethylenedioxythiophene）：poly（styrene sul- fonate） （PEDOT：PSS） film in vacuum with 254-nm ultraviolet （UV） light. The mechanism for such an improvement is investigated by photoelectron yield spectroscopy, X-ray photo electron energy spectrum, and field emission technique. Sur- face oxidation and composition change are found as the reasons for work function increase. The UV-treated PEDOT：PSS film is used as the hole injection layer in a hole-only device. Hole injection is improved by UV-treated PEDOT：PSS film without baring the enlargement of film resistance. Our result demonstrates that UV treatment is more suitable for modifying the injection barrier than UV ozone exposure.
文摘Recently, increasing attention has been paid to magneto-conjugated polymer core-shell nanoparticles （NPs） as theranostic platforms. However, the utilization of surfactants and extra oxidizing agents with potential toxicity in synthesis, the lack of general methods for the controlled synthesis of various kinds of magnetic NP （MNP）@conjugated polymer NPs, and the difficulty of obtaining balanced magneto-optical properties have greatly limited the applications of magneto-conjugated polymers in theranostics. We developed an in situ surface polymerization method free of extra surfactants and oxidizing agents to synthesize MNP@polypyrrole （PPy） NPs with balanced, prominent magneto-optical properties. MNP@PPy NPs with an adjustable size, different shapes, and a controlled shell thickness were obtained using this method. The method was extended to synthesize other MNP-conjugated polymer core-shell NPs, such as MNP@polyaniline and MNP@poly（3,4-ethylenedioxythiophene）：poly（4- styrenesulfonate） （PEDOT：PSS）. We discuss the formation mechanism of the proposed method according to our experimental results. Finally, using the optical and magnetic properties of the obtained MNP@PEDOT：PSS NPs, in vivo multimodal imaging-guided hyperthermia was induced in mice, achieving an excellent tumor-ablation therapeutic effect. Our work is beneficial for extending the application of MNP-conjugated polymer core-shell NPs in the biomedical field.
基金We acknowledge the financial support provided by the National Young Natural Science Foundation of China （Grant No. 61306067） and the Fundamental Research Funds for the Central Universities in Huazhong University of Science and Technology （Nos. 2014NY009 and 2016YXMS033）.
文摘In this paper, we fabricated an organic thermo- electric （TE） device with modified [6,6]-phenyl-C61- butyric acid methyl ester （PCBM） and poly（3,4-ethylene- dioxythiophene） polystyrene sulfonate （PEDOT：PSS）; the device showed good stability in air condition. For n-leg, PCBM were doped with acridine orange base （3,6-bis （dimethylamino）acridine） （AOB） and 1,3-dimethyl-2,3- dihydro- 1H-benzoimidazole （N-DMBI）. Co-doped PCBM utilizes synergistic effects of AOB and N-DMBI, resulting in excellent electrical conductivity and Seebeck coefficient values reaching 2 S/cm and -500 μV/K, respectively, at room temperature with dopant molar ratio of 0.11. P-type leg used modified PEDOT：PSS. Based on modified PCBM and PEDOT：PSS materials, we fabricated a TE module device with 48 p-type and n-type thermocouple and tested their output voltage, short current, and power. Output voltage measured -0.82 V, and generated power reached almost 945 μW with 75 K temperature gradient at 453 K hot-side temperature. These promising results showed potential of modified PEDOT and PCBM as TE materials for application in device optimization.
基金the National Natural Science Foundation of China(Nos.22104021,52303075,and 22309105)Natural Science Foundation of Shandong Province(No.ZR2023QB227)+1 种基金Department of Science and Technology of Guangdong Province(No.2022A1515110014)Taishan Young Scholar Program(Nos.tsqn202306267 and tsqnz20231235).
文摘The issue of sensitivity attenuation in high-pressure region has been a persistent concern for pressure-sensitive electronic skins.In order to tackle such trade-off between sensitivity and linear range,herein,a hybrid piezoresistive-supercapacitive(HRSC)strategy is proposed via introducing a piezoresistive porous aerogel layer between the charge collecting electrodes and iontronic films of the pressure sensors.Surprisingly,the HRSC-induced impedance regulation and supercapacitive behavior contribute to significant mitigation in sensitivity attenuation,achieving high sensitivity across wide linear range(44.58 kPa^(−1)from 0 to 3 kPa and 23.6 kPa^(−1)from 3 to 12 kPa).The HRSC pressure sensor exhibits a low detection limit of 1 Pa,fast responsiveness(~130 ms),and excellent cycling stability,allowing to detect tiny pressure of air flow,finger bending,and human respiration.Meanwhile,the HRSC sensor exhibits exceptional perception capabilities for proximity and temperature,broadening its application scenarios in prosthetic perception and electronic skin.The proposed HRSC strategy may boost the ongoing research on structural design of high-performance and multimodal electronic sensors.
基金the National Natural Science Foundation of China(Nos.11674185,61875015,and 61971049)the Natural Science Foundation of Fujian(Nos.2020J01857 and 2019J01764)+4 种基金the Fuzhou City Science and Technology Cooperation Project(Nos.2020-GX-5 and 2020-S-29)Beijing Natural Science Foundation(No.JQ20038)the Key Scientific Research Project of Beijing Municipal Commission of Education(No.KZ202010015024)the Research and Development Program of Beijing Institute of Graphic Communication(No.Ec202006)the Beijing Municipal Science and Technology Commission(No.Z181100004418004).
文摘Recently,stretchable and wearable health monitoring equipment has greatly improved human’s daily life,which sets higher demands for portable power source in stretchability,sustainability,and biocompatibility.In this work,we proposed a stretchable triboelectric nanogenerator(TENG)based on stretchable poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS)/porous carbon hybrid for oxyhemoglobin saturation(SpO2)monitoring.To combine advantages of carbon material for its high conductivity and organic electrode for its high stretchability,we spin-coated a solution of PEDOT:PSS/porous carbon onto a plasma-treated pre-stretched Ecoflex film to fabricate a stretchable electrode with rough surface.Due to its roughness and high potential difference with the dielectric material,the stretchable-electrode-based TENG exhibited better performance compared to the pristine TENG based on carbon or PEDOT:PSS material.The output voltage and current reached up to 51.5 V and 13.2μA as the carbon concentration increased.More importantly,the performance further increased under large strain(100%)which is suitable for wearable systems.Finally,the device demonstrated its application potential for powering a flexible blood oxygen monitor.This simple and cost-effective method can enhance the stretchability and stability of organic/inorganic electrode-based TENG,which paves the development of high-performance stretchable TENG.
