Polyphenols,such as procyanidins and anthocyanins,as naturalα-amylase inhibitors,have been extremely studied about their inhibitory activity in vitro.In this work,molecular docking was used to explore the efficacy of...Polyphenols,such as procyanidins and anthocyanins,as naturalα-amylase inhibitors,have been extremely studied about their inhibitory activity in vitro.In this work,molecular docking was used to explore the efficacy of wine anthocyanins and their polymeric pigments to inhibit human pancreaticα-amylase(HPA)and salivaryα-amylase(HSA).Three residues,ASP197,GLU233 and ASP300 were proposed as main interacting residues with both HPA and HSA.Hydrogen bonds,π-πstacking,hydrophobic interaction and electrostatic interaction played important roles in binding.Polymeric pigments showed stronger affinity with HPA and might be a potentialα-amylase inhibitor.Moreover,according to the docking result of HSA,polymeric pigments exhibited more impact on astringency than anthocyanins.展开更多
A double-layer aluminum consisting of an aluminum core and a shellof SiO2 and polyacrylic acid was synthesized.This modified aluminum was used to improve the corrosion resistance and dispersive property of aluminum in...A double-layer aluminum consisting of an aluminum core and a shellof SiO2 and polyacrylic acid was synthesized.This modified aluminum was used to improve the corrosion resistance and dispersive property of aluminum in waterborne media.TEM,FTIR,XPS,and EDX determination showed that PAA and SiO2 were coated on the surface of aluminum.Evolved hydrogen detection showed that the corrosion resistance of composite particle had been markedly improved.Maximum corrosion inhibition efficiency of SiO2 coated aluminum（SiO2@Al）was 95.1% while that of double-layer coated aluminum（PAA/SiO2@Al）was 98.8%.Meanwhile,polyacrylic acid layer improved the agglomeration of aluminum significantly.According to the dispersibility test,the particle size of 50% volume fraction [d（0.5）] of aluminum,SiO2@Aland PAA/SiO2@Alwere 42,53,and 34 μm,respectively.展开更多
文摘Polyphenols,such as procyanidins and anthocyanins,as naturalα-amylase inhibitors,have been extremely studied about their inhibitory activity in vitro.In this work,molecular docking was used to explore the efficacy of wine anthocyanins and their polymeric pigments to inhibit human pancreaticα-amylase(HPA)and salivaryα-amylase(HSA).Three residues,ASP197,GLU233 and ASP300 were proposed as main interacting residues with both HPA and HSA.Hydrogen bonds,π-πstacking,hydrophobic interaction and electrostatic interaction played important roles in binding.Polymeric pigments showed stronger affinity with HPA and might be a potentialα-amylase inhibitor.Moreover,according to the docking result of HSA,polymeric pigments exhibited more impact on astringency than anthocyanins.
基金Funded by the National Natural Science Foundation of China(31170558)the Fundamental Research Funds for the Central Universities(410500006)
文摘A double-layer aluminum consisting of an aluminum core and a shellof SiO2 and polyacrylic acid was synthesized.This modified aluminum was used to improve the corrosion resistance and dispersive property of aluminum in waterborne media.TEM,FTIR,XPS,and EDX determination showed that PAA and SiO2 were coated on the surface of aluminum.Evolved hydrogen detection showed that the corrosion resistance of composite particle had been markedly improved.Maximum corrosion inhibition efficiency of SiO2 coated aluminum（SiO2@Al）was 95.1% while that of double-layer coated aluminum（PAA/SiO2@Al）was 98.8%.Meanwhile,polyacrylic acid layer improved the agglomeration of aluminum significantly.According to the dispersibility test,the particle size of 50% volume fraction [d（0.5）] of aluminum,SiO2@Aland PAA/SiO2@Alwere 42,53,and 34 μm,respectively.
