目的分析年龄因素对于儿童肥胖与阻塞性睡眠呼吸暂停(OSA)关联性的影响,探寻OSA个性化差异化临床管理策略。方法回顾性分析自2021-2022年我院接受多导睡眠呼吸监测的133例3~12岁患儿相关临床资料,以肥胖患儿(n=32)为观察组,非肥胖病例...目的分析年龄因素对于儿童肥胖与阻塞性睡眠呼吸暂停(OSA)关联性的影响,探寻OSA个性化差异化临床管理策略。方法回顾性分析自2021-2022年我院接受多导睡眠呼吸监测的133例3~12岁患儿相关临床资料,以肥胖患儿(n=32)为观察组,非肥胖病例为对照组(n=101)。比较肥胖组与非肥胖组患儿的OSA发病率以及各项PSG参数值差异。结果在总的人群中以及学龄前(3~6岁)儿童中OSA发病率以及各项PSG参数值无显著差异。学龄(7~12岁)儿童中肥胖组OSA发生率以及呼吸暂停低通气指数(AHI)、氧减指数(ODI)均高于非肥胖组(72.7%vs 25.7%;7.99±4.03 vs 2.98±1.92;4.40±3.35 vs 1.94±1.67),差异具有显著性意义(P均<0.05);患儿BMI与AHI、ODI正相关(r=0.632,P=0.000;r=0.508,P=0.000);BMI每增加1kg/m^(2) OSA风险增加30.9%。结论肥胖与OSA的关联性受到年龄因素影响,在学龄前儿童中并不显著,而对于学龄儿童,肥胖会显著增加OSA风险。针对肥胖儿童,通过生活方式干预和运动指导,改善体重管理是降低OSA风险的有力手段。展开更多
Insomnia is one of the most frequently observed sleep disorders, affecting nearly 10% of the general population. It has multiple etiological factors. Recently, it has been reported that EEG abnormalities are associate...Insomnia is one of the most frequently observed sleep disorders, affecting nearly 10% of the general population. It has multiple etiological factors. Recently, it has been reported that EEG abnormalities are associated with insomnia in patients previously diagnosed as idiopathic insomniacs. In addition, transcranial magnetic stimulation (TMS) has shown to be effective in the treatment of disorders characterized by neural hyper-excitability. Method: In the present study, patients with insomnia and EEG abnormalities were submitted to slow repetitive trans-cranial magnetic stimulation, for 15 minutes daily during 10 days. Polysomnographic recordings were performed before and after TMS. Results: The results indicate that the presence of EEG abnormalities significantly decreased after TMS. In addition, most of the sleep parameters showed significant improvement. Conclusions: These data support the notion that TMS is a reliable therapeutic tool for patients affected with abnormalities linked to neuronal hyper-excitability.展开更多
文摘目的分析年龄因素对于儿童肥胖与阻塞性睡眠呼吸暂停(OSA)关联性的影响,探寻OSA个性化差异化临床管理策略。方法回顾性分析自2021-2022年我院接受多导睡眠呼吸监测的133例3~12岁患儿相关临床资料,以肥胖患儿(n=32)为观察组,非肥胖病例为对照组(n=101)。比较肥胖组与非肥胖组患儿的OSA发病率以及各项PSG参数值差异。结果在总的人群中以及学龄前(3~6岁)儿童中OSA发病率以及各项PSG参数值无显著差异。学龄(7~12岁)儿童中肥胖组OSA发生率以及呼吸暂停低通气指数(AHI)、氧减指数(ODI)均高于非肥胖组(72.7%vs 25.7%;7.99±4.03 vs 2.98±1.92;4.40±3.35 vs 1.94±1.67),差异具有显著性意义(P均<0.05);患儿BMI与AHI、ODI正相关(r=0.632,P=0.000;r=0.508,P=0.000);BMI每增加1kg/m^(2) OSA风险增加30.9%。结论肥胖与OSA的关联性受到年龄因素影响,在学龄前儿童中并不显著,而对于学龄儿童,肥胖会显著增加OSA风险。针对肥胖儿童,通过生活方式干预和运动指导,改善体重管理是降低OSA风险的有力手段。
文摘Insomnia is one of the most frequently observed sleep disorders, affecting nearly 10% of the general population. It has multiple etiological factors. Recently, it has been reported that EEG abnormalities are associated with insomnia in patients previously diagnosed as idiopathic insomniacs. In addition, transcranial magnetic stimulation (TMS) has shown to be effective in the treatment of disorders characterized by neural hyper-excitability. Method: In the present study, patients with insomnia and EEG abnormalities were submitted to slow repetitive trans-cranial magnetic stimulation, for 15 minutes daily during 10 days. Polysomnographic recordings were performed before and after TMS. Results: The results indicate that the presence of EEG abnormalities significantly decreased after TMS. In addition, most of the sleep parameters showed significant improvement. Conclusions: These data support the notion that TMS is a reliable therapeutic tool for patients affected with abnormalities linked to neuronal hyper-excitability.
