The particle residence time distribution(RTD)and axial dispersion coefficient are key parameters for the design and operation of a pressurized circulating fluidized bed(PCFB).In this study,the effects of pressure(0.1-...The particle residence time distribution(RTD)and axial dispersion coefficient are key parameters for the design and operation of a pressurized circulating fluidized bed(PCFB).In this study,the effects of pressure(0.1-0.6 MPa),fluidizing gas velocity(2-7 m·s^(-1)),and solid circulation rate(10-90 kg·m^(-2)·s^(-1))on particle RTD and axial dispersion coefficient in a PCFB are numerically investigated based on the multiphase particle-in-cell(MP-PIC)method.The details of the gas-solid flow behaviors of PCFB are revealed.Based on the gas-solid flow pattern,the particles tend to move more orderly under elevated pressures.With an increase in either fluidizing gas velocity or solid circulation rate,the mean residence time of particles decreases while the axial dispersion coefficient increases.With an increase in pressure,the core-annulus flow is strengthened,which leads to a wider shape of the particle RTD curve and a larger mean particle residence time.The back-mixing of particles increases with increasing pressure,resulting in an increase in the axial dispersion coefficient.展开更多
Knowledge of pore-water pressure(PWP)variation is fundamental for slope stability.A precise prediction of PWP is difficult due to complex physical mechanisms and in situ natural variability.To explore the applicabilit...Knowledge of pore-water pressure(PWP)variation is fundamental for slope stability.A precise prediction of PWP is difficult due to complex physical mechanisms and in situ natural variability.To explore the applicability and advantages of recurrent neural networks(RNNs)on PWP prediction,three variants of RNNs,i.e.,standard RNN,long short-term memory(LSTM)and gated recurrent unit(GRU)are adopted and compared with a traditional static artificial neural network(ANN),i.e.,multi-layer perceptron(MLP).Measurements of rainfall and PWP of representative piezometers from a fully instrumented natural slope in Hong Kong are used to establish the prediction models.The coefficient of determination(R^2)and root mean square error(RMSE)are used for model evaluations.The influence of input time series length on the model performance is investigated.The results reveal that MLP can provide acceptable performance but is not robust.The uncertainty bounds of RMSE of the MLP model range from 0.24 kPa to 1.12 k Pa for the selected two piezometers.The standard RNN can perform better but the robustness is slightly affected when there are significant time lags between PWP changes and rainfall.The GRU and LSTM models can provide more precise and robust predictions than the standard RNN.The effects of the hidden layer structure and the dropout technique are investigated.The single-layer GRU is accurate enough for PWP prediction,whereas a double-layer GRU brings extra time cost with little accuracy improvement.The dropout technique is essential to overfitting prevention and improvement of accuracy.展开更多
In this paper,the research progress of the interfacial heat transfer in high pressure die casting(HPDC)is reviewed.Results including determination of the interfacial heat transfer coefficient(IHTC),influence of castin...In this paper,the research progress of the interfacial heat transfer in high pressure die casting(HPDC)is reviewed.Results including determination of the interfacial heat transfer coefficient(IHTC),influence of casting thickness,process parameters and casting alloys on the IHTC are summarized and discussed.A thermal boundary condition model was developed based on the two correlations:(a)IHTC and casting solid fraction and(b)IHTC peak value and initial die surface temperature.The boundary model was then applied during the determination of the temperature field in HPDC and excellent agreement was found.展开更多
This study aimed to show anisotropic poroelasticity evolution in ultra-low permeability reservoirs under pore pressure,confining pressure,and temperature.Several groups of experiments examining Biot's coefficient ...This study aimed to show anisotropic poroelasticity evolution in ultra-low permeability reservoirs under pore pressure,confining pressure,and temperature.Several groups of experiments examining Biot's coefficient under different conditions were carried out.Results showed that Biot's coefficient decreased with increased pore pressure,and the variation trend is linear,but the decreasing rate is variable between materials.Biot's coefficient increased with increased confining pressure;the variation trend is linear,but the increasing rate varies by material as well.Generally,Biot's coefficient remains stable with increased temperature.Lithology,clay mineral content,particle arrangement,and pore arrangement showed impacts on Biot's coefficient.For strong hydrophilic clay minerals,expansion in water could result in a strong surface adsorption reaction,which could result in an increased fluid bulk modulus and higher Biot's coefficient.For skeleton minerals with strong lipophilicity,such as quartz and feldspar,increased oil saturation will also result in an adsorption reaction,leading to increased fluid bulk modulus and a higher Biot's coefficient.The study's conclusions provide evidence of poroelasticity evolution of ultra-low permeability and help the enhancing oil recovery(EOR)process.展开更多
AIM:To combine pressure and flow parameter, pressure drop coefficient(CDP) will result in better clinical outcomes in comparison to the fractional flow reserve(FFR) group. METHODS:To test this hypothesis, a comparison...AIM:To combine pressure and flow parameter, pressure drop coefficient(CDP) will result in better clinical outcomes in comparison to the fractional flow reserve(FFR) group. METHODS:To test this hypothesis, a comparison was made between the FFR < 0.75 and CDP > 27.9 groups in this study, for the major adverse cardiac events [major adverse cardiac events(MACE): Primary outcome] and patients’ quality of life(secondary outcome). Further, a comparison was also made between the survival curves for the FFR < 0.75 and CDP > 27.9 groups. Two-tailed χ~2 test proportions were performed for the comparison of primary and secondary outcomes. Kaplan-Meier survival analysis was performed to compare the survival curves of FFR < 0.75 and CDP > 27.9 groups(MedcalcV10.2, Mariakerke, Belgium). Results were considered statistically significant for P < 0.05. RESULTS: The primary outcomes(%MACE) in the FFR < 0.75 group(20%, 4 out of 20) was not statistically different(P = 0.24) from the %MACE occurring in CDP > 27.9 group(8.57%, 2 out of 35). Noteworthy is the reduction in the %MACE in the CDP > 27.9 group, in comparison to the FFR < 0.75 group. Further, the secondary outcomes were not statistically significant between the FFR < 0.75 and CDP > 27.9 groups. Survival analysis results suggest that the survival time for the CDP > 27.9 group(n = 35) is significantly higher(P = 0.048) in comparison to the survival time for the FFR < 0.75 group(n = 20). The results remained similar for a FFR = 0.80 cut-off. CONCLUSION: Based on the above, CDP could prove to be a better diagnostic end-point for clinical revascularization decision-making in the cardiac catheterization laboratories.展开更多
AIM To investigate the patient-outcomes of newly developed pressure drop coefficient(CDP) in diagnosing epicardial stenosis(ES) in the presence of concomitant microvascular disease(MVD).METHODS Patients from our clini...AIM To investigate the patient-outcomes of newly developed pressure drop coefficient(CDP) in diagnosing epicardial stenosis(ES) in the presence of concomitant microvascular disease(MVD).METHODS Patients from our clinical trial were divided into two subgroups with:(1) cut-off of coronary flow reserve(CFR) < 2.0;and(2) diabetes.First,correlations were performed for both subgroups between CDP and hyperemic microvascular resistance(HMR),a diagnostic parameter for assessing the severity of MVD.Linear regression analysis was used for these correlations.Further,in each of the subgroups,comparisons were made between fractional flow reserve(FFR) < 0.75 and CDP > 27.9 groups for assessing major adverse cardiac events(MACE:Primary outcome).Comparisons were also made between the survival curves for FFR < 0.75 and CDP > 27.9 groups.Two tailed chi-squared and Fischer's exact tests were performed for comparison of the primary outcomes,and the log-rank test was used to compare the Kaplan-Meier survival curves.P < 0.05 for all tests was considered statistically significant.RESULTS Significant linear correlations were observed between CDP and HMR for both CFR < 2.0(r = 0.58,P < 0.001) and diabetic(r = 0.61,P < 0.001) patients.In the CFR < 2.0 subgroup,the %MACE(primary outcomes) for CDP > 27.9 group(7.7%,2/26) was lower than FFR < 0.75 group(3/14,21.4%);P = 0.21.Similarly,in the diabetic subgroup,the %MACE for CDP > 27.9 group(12.5%,2/16) was lower than FFR < 0.75 group(18.2%,2/11);P = 0.69.Survival analysis for CFR < 2.0 subgroup indicated better event-free survival for CDP > 27.9 group(n = 26) when compared with FFR < 0.75 group(n = 14);P = 0.10.Similarly,for the diabetic subgroup,CDP > 27.9 group(n = 16) showed higher survival times compared to FFR group(n = 11);P = 0.58.CONCLUSION CDP correlated significantly with HMR and resulted in better %MACE as well as survival rates in comparison to FFR.These positive trends demonstrate that CDP could be a potential diagnostic endpoint for delineating MVD with or without ES.展开更多
We have performed a first-principles investigation for the family of compounds ZnGa2X4 (X = S, Se, Te). The properties of two possible structures, defect chalcopyrite and defect famatinite are both calculated. We re...We have performed a first-principles investigation for the family of compounds ZnGa2X4 (X = S, Se, Te). The properties of two possible structures, defect chalcopyrite and defect famatinite are both calculated. We reveal that ZnGa2S4 and ZnGa2Se4 have direct band gaps, while ZnGa2Te4 has an indirect band gap. The local density approximation band gaps are found to be very different in two structures, while the lattice parameters and bulk moduli are similar. We extend Cohen's empirical formula for zinc-blende compounds to this family of compounds. The pressure coefficients are calculated and metallization pressures are discussed. We find that agi remains fairly constant when thegroup-V/element X is varied in ZnGa2X4(Ⅱ-Ⅲ2-Ⅵ4).展开更多
The diffusion coefficient of natural gas in foamy oil is one of the key parameters to evaluate the feasibility of gas injection for enhanced oil recovery in foamy oil reservoirs. In this paper, a PVT cell was used to ...The diffusion coefficient of natural gas in foamy oil is one of the key parameters to evaluate the feasibility of gas injection for enhanced oil recovery in foamy oil reservoirs. In this paper, a PVT cell was used to measure diffusion coefficients of natural gas in Venezuela foamy oil at high pressures, and a new method for deter- mining the diffusion coefficient in the foamy oil was de- veloped on the basis of experimental data. The effects of pressure and the types of the liquid phase on the diffusion coefficient of the natural gas were discussed. The results indicate that the diffusion coefficients of natural gas in foamy oil, saturated oil, and dead oil increase linearly with increasing pressure. The diffusion coefficient of natural gas in the foamy oil at 20 MPa was 2.93 times larger than that at 8.65 MPa. The diffusion coefficient of the natural gas in dead oil was 3.02 and 4.02 times than that of the natural gas in saturated oil and foamy oil when the pressure was 20 MPa. However, the gas content of foamy oil was 16.9 times higher than that of dead oil when the dissolution time and pressure were 20 MPa and 35.22 h, respectively.展开更多
In this study consecutive consolidated isotropically drained triaxial tests for the coefficient of earth pressure at rest(K_0) were carried out to investigate its rules of evolution as well as its strength characteris...In this study consecutive consolidated isotropically drained triaxial tests for the coefficient of earth pressure at rest(K_0) were carried out to investigate its rules of evolution as well as its strength characteristics for normal,consolidated saturated silt under high pressure.The tests results indicate that:1) for normal,consolidated saturated silt,K_0 values increase as the consolidation stress increases at high pressure levels,while the nonlinear characteristics of K_0 are inconspicuous compared to cohesive soils;2) the Jaky and Roscoe equations,used to calculate K_0,are only suitable for certain soils,but cannot represent these values for normal, consolidated saturated silt due to the variation in bilinear strength at high pressure;and 3) there are close relations between the nonlinear characteristics of K_0 and the void ratio,measured in the tests.Both share the same functional form while under pressure. Based on our experimental results,we developed an empirical linear model to interpret the rules of nonlinear variation for the coefficient of earth pressure at rest.展开更多
Exact calculations of the static earth pressure from a thick alluvium require accurate K0 values. These calculations influence the sinking cost and the safety of the freezing method. The static earth pressure coeffici...Exact calculations of the static earth pressure from a thick alluvium require accurate K0 values. These calculations influence the sinking cost and the safety of the freezing method. The static earth pressure coefficient (K0) of thick and deep soil was analyzed using laboratory tests. The results show that the static earth pressure coefficient of thick and deep soils is nonlinear and different from that of superficial soils. The constant of superficial soils is usually invariant and the total stress or incremental stress definitions used in traditional geo-mechanics give the same value. The influence of load increments when calculating for superficial soil is ignored. The difference in values of K0 for thick alluvium defined by the total stress or the incremental stress methods is over 10%. The effects of the thick alluvium on K0 should be considered during the design of frozen shaft projects. Such things as the frozen shaft thickness and the excavated section height should be chosen to assure the rationality of the design and to avoid potential faults and accidents.展开更多
The static earth pressure coefficient of soils is,approximately,considered to be a constant in the view of clas-sical soil mechanics. This is supported by many research results. The high pressure experimental research...The static earth pressure coefficient of soils is,approximately,considered to be a constant in the view of clas-sical soil mechanics. This is supported by many research results. The high pressure experimental research and analysis of remolding deep soil described herein indicate that the static earth pressure of thick overburden has a notable non lin-ear characteristic. It also appears larger than that of superficial soils. It is necessary for deep coal mine design and con-struction to consider this particularity of soil pressure so as to avoid engineering accidents and heavy loss of life and property.展开更多
In order to obtain the earth pressure coefficient at rest (K0) at higher consolidation pressures during secondary compression, a series of K0 tests for saturated reconstituted clay were conducted. The results indicate...In order to obtain the earth pressure coefficient at rest (K0) at higher consolidation pressures during secondary compression, a series of K0 tests for saturated reconstituted clay were conducted. The results indicate that the measured K0 in secondary compression can be described by equations related to internal friction angle, secondary compression coefficient, compression index, recompression index, and sediment time. Effects of consolidation pressures and sediment time on K0 during secondary compression can be attributed to cementation (part of cohesion) increase and internal friction angle decrease. Cementation increase leads to nonlinear variation for K0 and internal friction angle decrease results in increase of K0. K0 computed by equations associated with internal friction angle is overestimated at apparent lower consolidation pressures with different sediment time, which agrees with the measured values well at apparent higher consolidation pressures.展开更多
The high pressure die casting (HPDC) process is one of the fastest growing and most efficient methods for the production of complex shape castings of magnesium and aluminum alloys in today's manufacturing industry...The high pressure die casting (HPDC) process is one of the fastest growing and most efficient methods for the production of complex shape castings of magnesium and aluminum alloys in today's manufacturing industry. In this study, a high pressure die casting experiment using AZ91D magnesium alloy was conducted, and the temperature profiles inside the die were measured. By using a computer program based on solving the inverse heat problem, the metal/die interfacial heat transfer coefficient (IHTC) was calculated and studied. The results show that the IHTC between the metal and die increases right after the liquid metal is brought into the cavity by the plunger, and decreases as the solidification process of the liquid metal proceeds until the liquid metal is completely solidified, when the IHTC tends to be stable. The interfacial heat transfer coefficient shows different characteristics under different casting wall thicknesses and varies with the change of solidification behavior.展开更多
Orifice plate energy dissipaters have been successfully used in large-scale hydropower projects due to their simple structure, convenient construction procedure, and high energy dissipation ratio. The minimum wall pre...Orifice plate energy dissipaters have been successfully used in large-scale hydropower projects due to their simple structure, convenient construction procedure, and high energy dissipation ratio. The minimum wall pressure coefficient of an orifice plate can indirectly reflect its cavitation characteristics: the lower the minimum wall pressure coefficient is, the better the ability of the orifice plate to resist cavitation damage is. Thus, it is important to study the minimum wall pressure coefficient of the orifice plate. In this study, this coefficient and related parameters, such as the contraction ratio, defined as the ratio of the orifice plate diameter to the flood-discharging tunnel diameter; the relative thickness, defined as the ratio of the orifice plate thickness to the tunnel diameter; and the Reynolds number of the flow through the orifice plate, were theoretically analyzed, and their relationships were obtained through physical model experiments. It can be concluded that the minimum wall pressure coefficient is mainly dominated by the contraction ratio and relative thickness. The lower the contraction ratio and relative thickness are, the larger the minimum wall pressure coefficient is. The effects of the Reynolds number on the minimum wall pressure coefficient can be neglected when it is larger than 10^5. An emoirical expression was presented to calculate the minimum wall oressure coefficient in this study.展开更多
A computational approach is presented to handle an enlarged linear rotordynamic model whichsimultaneously includes both radial and misalignment motions.The interactive force and momentbetween the rotating and non-rota...A computational approach is presented to handle an enlarged linear rotordynamic model whichsimultaneously includes both radial and misalignment motions.The interactive force and momentbetween the rotating and non-rotating members are modeled using an adaptation of the classicalReynolds lubrication equation for incompressible laminar isoviscous films.First,the governingequation is derived and the method of solution is introduced based on a 2-dimension,9-point cen-tral difference.Second,force and moment components are computed by numerical integration ofthe film pressure distribution.Finally,the rotordynamic coefficients are yielded according to thegeneralized force gradients.展开更多
A calibration test was done in order to measure its sensitivity coefficient by an improved soil test device.The experimental result shows that the soil pressure min-sensor made of the monocrystalline silicon(SPMMS)i...A calibration test was done in order to measure its sensitivity coefficient by an improved soil test device.The experimental result shows that the soil pressure min-sensor made of the monocrystalline silicon(SPMMS)is proved to be good linear,high precision and less that can fetch precise data in low pressure range even near by O point,which guarantees the reliability of the soil pressure test in geotechnical engineering.展开更多
A throttling experiment for the multi-hole orifice (MO) using water was conducted based on the conclusion of key parameters affecting the MO throttling performance. Testing MOs and standard orifice plates (SOs) were d...A throttling experiment for the multi-hole orifice (MO) using water was conducted based on the conclusion of key parameters affecting the MO throttling performance. Testing MOs and standard orifice plates (SOs) were designed for the throttling experiment to compare the throttling effect using the equivalent diameter ratio (RED) and diameter ratio (RD) as key parameters, respectively. Meanwhile, effective metrical conditions were provided for experimental accuracy. The throttling model form was determined according to the theoretical throttling model of SO. Then the unknown parameters involved were identified by experimental data. A good concordance between the modeling computation and experimental results shows a validation of the MO throtting model.展开更多
A wind tunnel tests with different configurations,pitch and yaw angles were performed to study the wind load characteristics of the rigid model of the airship Zhiyuan-1. The rigid model was aimed to simulate a technic...A wind tunnel tests with different configurations,pitch and yaw angles were performed to study the wind load characteristics of the rigid model of the airship Zhiyuan-1. The rigid model was aimed to simulate a technical demonstrating stratospheric airship named Zhiyuan-1 according to the similarity principle of geometric and Reynolds number. Based on the results of wind tunnel test,the features of pressure coefficient distributions on the surface of the airship were described. It was indicated that the fins and the gondola of airship hardly have the effect on the pressure distribution on the surface of airship,but have obviously effect on the local areas near the fins and the gondola.展开更多
This study explains the relationship between friction coefficient and pressure change at a range of Reynolds (21,056 - 28,574) and (0 - 1.4) solid loading ratio of two-phase flow (gas-solid) inside a circular copper p...This study explains the relationship between friction coefficient and pressure change at a range of Reynolds (21,056 - 28,574) and (0 - 1.4) solid loading ratio of two-phase flow (gas-solid) inside a circular copper pipe by using laboratory apparatus and solving the equations mathematically. An experimentally relationship of friction coefficient and pressure change with Reynolds number and flow velocity obtained also the relationship between the Solid loading ratio with friction coefficient and pressure change has been done for a Limit range of Reynolds number. It was noticed that the increase in friction coefficient and pressure change for two-phase flow was occurred when solid loading ratio increased. Also the relationship between pressure change and Reynolds number was direct proportion while the relationship between friction coefficient and Reynolds Number was inversely related.展开更多
According the Coulomb earth pressure theory,it is obtained that,for normally consolidated soils,the lateral pressure coefficient of a soil at rest is equal to 1,and it is independent of the soil type,either granular o...According the Coulomb earth pressure theory,it is obtained that,for normally consolidated soils,the lateral pressure coefficient of a soil at rest is equal to 1,and it is independent of the soil type,either granular or cohesive;or that the material is in a loose or compact state;hard or a soft cohesive soil.Also,a methodology to calculate the earth pressure for intermediate states between at rest condition and the active pressure is presented.In addition,a methodology to calculate the earth pressure for intermediate states between at rest condition and the passive pressure is presented.Two practical examples are presented:one for a frictionless wall;and another for a coarse wall.Practical recommendations are given for the use of the lateral earth pressure coefficient for different applications.展开更多
基金Financial support of this work by National Natural Science Foundation of China(51976037)。
文摘The particle residence time distribution(RTD)and axial dispersion coefficient are key parameters for the design and operation of a pressurized circulating fluidized bed(PCFB).In this study,the effects of pressure(0.1-0.6 MPa),fluidizing gas velocity(2-7 m·s^(-1)),and solid circulation rate(10-90 kg·m^(-2)·s^(-1))on particle RTD and axial dispersion coefficient in a PCFB are numerically investigated based on the multiphase particle-in-cell(MP-PIC)method.The details of the gas-solid flow behaviors of PCFB are revealed.Based on the gas-solid flow pattern,the particles tend to move more orderly under elevated pressures.With an increase in either fluidizing gas velocity or solid circulation rate,the mean residence time of particles decreases while the axial dispersion coefficient increases.With an increase in pressure,the core-annulus flow is strengthened,which leads to a wider shape of the particle RTD curve and a larger mean particle residence time.The back-mixing of particles increases with increasing pressure,resulting in an increase in the axial dispersion coefficient.
基金supported by the Natural Science Foundation of China(Grant Nos.51979158,51639008,51679135,and 51422905)the Program of Shanghai Academic Research Leader by Science and Technology Commission of Shanghai Municipality(Project No.19XD1421900)。
文摘Knowledge of pore-water pressure(PWP)variation is fundamental for slope stability.A precise prediction of PWP is difficult due to complex physical mechanisms and in situ natural variability.To explore the applicability and advantages of recurrent neural networks(RNNs)on PWP prediction,three variants of RNNs,i.e.,standard RNN,long short-term memory(LSTM)and gated recurrent unit(GRU)are adopted and compared with a traditional static artificial neural network(ANN),i.e.,multi-layer perceptron(MLP).Measurements of rainfall and PWP of representative piezometers from a fully instrumented natural slope in Hong Kong are used to establish the prediction models.The coefficient of determination(R^2)and root mean square error(RMSE)are used for model evaluations.The influence of input time series length on the model performance is investigated.The results reveal that MLP can provide acceptable performance but is not robust.The uncertainty bounds of RMSE of the MLP model range from 0.24 kPa to 1.12 k Pa for the selected two piezometers.The standard RNN can perform better but the robustness is slightly affected when there are significant time lags between PWP changes and rainfall.The GRU and LSTM models can provide more precise and robust predictions than the standard RNN.The effects of the hidden layer structure and the dropout technique are investigated.The single-layer GRU is accurate enough for PWP prediction,whereas a double-layer GRU brings extra time cost with little accuracy improvement.The dropout technique is essential to overfitting prevention and improvement of accuracy.
基金supported by the National Major Science and Technology Program of China(2012ZX04012011)the National Nature Science Foundation of China(51275269)
文摘In this paper,the research progress of the interfacial heat transfer in high pressure die casting(HPDC)is reviewed.Results including determination of the interfacial heat transfer coefficient(IHTC),influence of casting thickness,process parameters and casting alloys on the IHTC are summarized and discussed.A thermal boundary condition model was developed based on the two correlations:(a)IHTC and casting solid fraction and(b)IHTC peak value and initial die surface temperature.The boundary model was then applied during the determination of the temperature field in HPDC and excellent agreement was found.
基金This work was supported by PetroChina Innovation Foundation(Grant No.2019D-5007-0214).
文摘This study aimed to show anisotropic poroelasticity evolution in ultra-low permeability reservoirs under pore pressure,confining pressure,and temperature.Several groups of experiments examining Biot's coefficient under different conditions were carried out.Results showed that Biot's coefficient decreased with increased pore pressure,and the variation trend is linear,but the decreasing rate is variable between materials.Biot's coefficient increased with increased confining pressure;the variation trend is linear,but the increasing rate varies by material as well.Generally,Biot's coefficient remains stable with increased temperature.Lithology,clay mineral content,particle arrangement,and pore arrangement showed impacts on Biot's coefficient.For strong hydrophilic clay minerals,expansion in water could result in a strong surface adsorption reaction,which could result in an increased fluid bulk modulus and higher Biot's coefficient.For skeleton minerals with strong lipophilicity,such as quartz and feldspar,increased oil saturation will also result in an adsorption reaction,leading to increased fluid bulk modulus and a higher Biot's coefficient.The study's conclusions provide evidence of poroelasticity evolution of ultra-low permeability and help the enhancing oil recovery(EOR)process.
基金Supported by VA Merit Review Grant(I01CX000342-01),Department of Veteran Affairs
文摘AIM:To combine pressure and flow parameter, pressure drop coefficient(CDP) will result in better clinical outcomes in comparison to the fractional flow reserve(FFR) group. METHODS:To test this hypothesis, a comparison was made between the FFR < 0.75 and CDP > 27.9 groups in this study, for the major adverse cardiac events [major adverse cardiac events(MACE): Primary outcome] and patients’ quality of life(secondary outcome). Further, a comparison was also made between the survival curves for the FFR < 0.75 and CDP > 27.9 groups. Two-tailed χ~2 test proportions were performed for the comparison of primary and secondary outcomes. Kaplan-Meier survival analysis was performed to compare the survival curves of FFR < 0.75 and CDP > 27.9 groups(MedcalcV10.2, Mariakerke, Belgium). Results were considered statistically significant for P < 0.05. RESULTS: The primary outcomes(%MACE) in the FFR < 0.75 group(20%, 4 out of 20) was not statistically different(P = 0.24) from the %MACE occurring in CDP > 27.9 group(8.57%, 2 out of 35). Noteworthy is the reduction in the %MACE in the CDP > 27.9 group, in comparison to the FFR < 0.75 group. Further, the secondary outcomes were not statistically significant between the FFR < 0.75 and CDP > 27.9 groups. Survival analysis results suggest that the survival time for the CDP > 27.9 group(n = 35) is significantly higher(P = 0.048) in comparison to the survival time for the FFR < 0.75 group(n = 20). The results remained similar for a FFR = 0.80 cut-off. CONCLUSION: Based on the above, CDP could prove to be a better diagnostic end-point for clinical revascularization decision-making in the cardiac catheterization laboratories.
基金Supported by VA Merit Review Grant,Department of Veteran Affairs(PI:Dr.Rupak K Banerjee)No.I01CX000342-01
文摘AIM To investigate the patient-outcomes of newly developed pressure drop coefficient(CDP) in diagnosing epicardial stenosis(ES) in the presence of concomitant microvascular disease(MVD).METHODS Patients from our clinical trial were divided into two subgroups with:(1) cut-off of coronary flow reserve(CFR) < 2.0;and(2) diabetes.First,correlations were performed for both subgroups between CDP and hyperemic microvascular resistance(HMR),a diagnostic parameter for assessing the severity of MVD.Linear regression analysis was used for these correlations.Further,in each of the subgroups,comparisons were made between fractional flow reserve(FFR) < 0.75 and CDP > 27.9 groups for assessing major adverse cardiac events(MACE:Primary outcome).Comparisons were also made between the survival curves for FFR < 0.75 and CDP > 27.9 groups.Two tailed chi-squared and Fischer's exact tests were performed for comparison of the primary outcomes,and the log-rank test was used to compare the Kaplan-Meier survival curves.P < 0.05 for all tests was considered statistically significant.RESULTS Significant linear correlations were observed between CDP and HMR for both CFR < 2.0(r = 0.58,P < 0.001) and diabetic(r = 0.61,P < 0.001) patients.In the CFR < 2.0 subgroup,the %MACE(primary outcomes) for CDP > 27.9 group(7.7%,2/26) was lower than FFR < 0.75 group(3/14,21.4%);P = 0.21.Similarly,in the diabetic subgroup,the %MACE for CDP > 27.9 group(12.5%,2/16) was lower than FFR < 0.75 group(18.2%,2/11);P = 0.69.Survival analysis for CFR < 2.0 subgroup indicated better event-free survival for CDP > 27.9 group(n = 26) when compared with FFR < 0.75 group(n = 14);P = 0.10.Similarly,for the diabetic subgroup,CDP > 27.9 group(n = 16) showed higher survival times compared to FFR group(n = 11);P = 0.58.CONCLUSION CDP correlated significantly with HMR and resulted in better %MACE as well as survival rates in comparison to FFR.These positive trends demonstrate that CDP could be a potential diagnostic endpoint for delineating MVD with or without ES.
基金Project supported by the National Natural Science Foundation of China (Grant No. 10604040)Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Mininstry+1 种基金the Youth Scientific Research Foundation of Shanxi Province (Grant No. 2007021002)the Oversea Science Foundation of Shanxi Province
文摘We have performed a first-principles investigation for the family of compounds ZnGa2X4 (X = S, Se, Te). The properties of two possible structures, defect chalcopyrite and defect famatinite are both calculated. We reveal that ZnGa2S4 and ZnGa2Se4 have direct band gaps, while ZnGa2Te4 has an indirect band gap. The local density approximation band gaps are found to be very different in two structures, while the lattice parameters and bulk moduli are similar. We extend Cohen's empirical formula for zinc-blende compounds to this family of compounds. The pressure coefficients are calculated and metallization pressures are discussed. We find that agi remains fairly constant when thegroup-V/element X is varied in ZnGa2X4(Ⅱ-Ⅲ2-Ⅵ4).
基金financial support from the Major Subject of National Science and Technology (2011ZX05032-001)the Fundamental Research Funds for the Central Universities(NO.11CX06022A)
文摘The diffusion coefficient of natural gas in foamy oil is one of the key parameters to evaluate the feasibility of gas injection for enhanced oil recovery in foamy oil reservoirs. In this paper, a PVT cell was used to measure diffusion coefficients of natural gas in Venezuela foamy oil at high pressures, and a new method for deter- mining the diffusion coefficient in the foamy oil was de- veloped on the basis of experimental data. The effects of pressure and the types of the liquid phase on the diffusion coefficient of the natural gas were discussed. The results indicate that the diffusion coefficients of natural gas in foamy oil, saturated oil, and dead oil increase linearly with increasing pressure. The diffusion coefficient of natural gas in the foamy oil at 20 MPa was 2.93 times larger than that at 8.65 MPa. The diffusion coefficient of the natural gas in dead oil was 3.02 and 4.02 times than that of the natural gas in saturated oil and foamy oil when the pressure was 20 MPa. However, the gas content of foamy oil was 16.9 times higher than that of dead oil when the dissolution time and pressure were 20 MPa and 35.22 h, respectively.
基金Financial support for this work,provided by the National Natural Science Foundation of China (No.50534040)the Project of the Science and Technology Ministry of China(No.2006BAB16B01)the Post Graduate Research Project of Jiangsu Province (No.CX08B_103Z),
文摘In this study consecutive consolidated isotropically drained triaxial tests for the coefficient of earth pressure at rest(K_0) were carried out to investigate its rules of evolution as well as its strength characteristics for normal,consolidated saturated silt under high pressure.The tests results indicate that:1) for normal,consolidated saturated silt,K_0 values increase as the consolidation stress increases at high pressure levels,while the nonlinear characteristics of K_0 are inconspicuous compared to cohesive soils;2) the Jaky and Roscoe equations,used to calculate K_0,are only suitable for certain soils,but cannot represent these values for normal, consolidated saturated silt due to the variation in bilinear strength at high pressure;and 3) there are close relations between the nonlinear characteristics of K_0 and the void ratio,measured in the tests.Both share the same functional form while under pressure. Based on our experimental results,we developed an empirical linear model to interpret the rules of nonlinear variation for the coefficient of earth pressure at rest.
基金Project BK2007040 supported by the Provincial Natural Science Foundation of Jiangsu, China
文摘Exact calculations of the static earth pressure from a thick alluvium require accurate K0 values. These calculations influence the sinking cost and the safety of the freezing method. The static earth pressure coefficient (K0) of thick and deep soil was analyzed using laboratory tests. The results show that the static earth pressure coefficient of thick and deep soils is nonlinear and different from that of superficial soils. The constant of superficial soils is usually invariant and the total stress or incremental stress definitions used in traditional geo-mechanics give the same value. The influence of load increments when calculating for superficial soil is ignored. The difference in values of K0 for thick alluvium defined by the total stress or the incremental stress methods is over 10%. The effects of the thick alluvium on K0 should be considered during the design of frozen shaft projects. Such things as the frozen shaft thickness and the excavated section height should be chosen to assure the rationality of the design and to avoid potential faults and accidents.
基金Project 50534040 supported by the National Natrual Science Foundation of China
文摘The static earth pressure coefficient of soils is,approximately,considered to be a constant in the view of clas-sical soil mechanics. This is supported by many research results. The high pressure experimental research and analysis of remolding deep soil described herein indicate that the static earth pressure of thick overburden has a notable non lin-ear characteristic. It also appears larger than that of superficial soils. It is necessary for deep coal mine design and con-struction to consider this particularity of soil pressure so as to avoid engineering accidents and heavy loss of life and property.
基金Projects(50534040, 50974117) supported by the National Natural Science Foundation of ChinaProject(20110491489) supported by China Postdoctoral Science FoundationProject(2011QNA03) supported by Fundamental Research Funds for Central Universities, China
文摘In order to obtain the earth pressure coefficient at rest (K0) at higher consolidation pressures during secondary compression, a series of K0 tests for saturated reconstituted clay were conducted. The results indicate that the measured K0 in secondary compression can be described by equations related to internal friction angle, secondary compression coefficient, compression index, recompression index, and sediment time. Effects of consolidation pressures and sediment time on K0 during secondary compression can be attributed to cementation (part of cohesion) increase and internal friction angle decrease. Cementation increase leads to nonlinear variation for K0 and internal friction angle decrease results in increase of K0. K0 computed by equations associated with internal friction angle is overestimated at apparent lower consolidation pressures with different sediment time, which agrees with the measured values well at apparent higher consolidation pressures.
文摘The high pressure die casting (HPDC) process is one of the fastest growing and most efficient methods for the production of complex shape castings of magnesium and aluminum alloys in today's manufacturing industry. In this study, a high pressure die casting experiment using AZ91D magnesium alloy was conducted, and the temperature profiles inside the die were measured. By using a computer program based on solving the inverse heat problem, the metal/die interfacial heat transfer coefficient (IHTC) was calculated and studied. The results show that the IHTC between the metal and die increases right after the liquid metal is brought into the cavity by the plunger, and decreases as the solidification process of the liquid metal proceeds until the liquid metal is completely solidified, when the IHTC tends to be stable. The interfacial heat transfer coefficient shows different characteristics under different casting wall thicknesses and varies with the change of solidification behavior.
基金supported by the Zhejiang Provincial Natural Science Foundation(Grant No.Y15E090022)
文摘Orifice plate energy dissipaters have been successfully used in large-scale hydropower projects due to their simple structure, convenient construction procedure, and high energy dissipation ratio. The minimum wall pressure coefficient of an orifice plate can indirectly reflect its cavitation characteristics: the lower the minimum wall pressure coefficient is, the better the ability of the orifice plate to resist cavitation damage is. Thus, it is important to study the minimum wall pressure coefficient of the orifice plate. In this study, this coefficient and related parameters, such as the contraction ratio, defined as the ratio of the orifice plate diameter to the flood-discharging tunnel diameter; the relative thickness, defined as the ratio of the orifice plate thickness to the tunnel diameter; and the Reynolds number of the flow through the orifice plate, were theoretically analyzed, and their relationships were obtained through physical model experiments. It can be concluded that the minimum wall pressure coefficient is mainly dominated by the contraction ratio and relative thickness. The lower the contraction ratio and relative thickness are, the larger the minimum wall pressure coefficient is. The effects of the Reynolds number on the minimum wall pressure coefficient can be neglected when it is larger than 10^5. An emoirical expression was presented to calculate the minimum wall oressure coefficient in this study.
文摘A computational approach is presented to handle an enlarged linear rotordynamic model whichsimultaneously includes both radial and misalignment motions.The interactive force and momentbetween the rotating and non-rotating members are modeled using an adaptation of the classicalReynolds lubrication equation for incompressible laminar isoviscous films.First,the governingequation is derived and the method of solution is introduced based on a 2-dimension,9-point cen-tral difference.Second,force and moment components are computed by numerical integration ofthe film pressure distribution.Finally,the rotordynamic coefficients are yielded according to thegeneralized force gradients.
文摘A calibration test was done in order to measure its sensitivity coefficient by an improved soil test device.The experimental result shows that the soil pressure min-sensor made of the monocrystalline silicon(SPMMS)is proved to be good linear,high precision and less that can fetch precise data in low pressure range even near by O point,which guarantees the reliability of the soil pressure test in geotechnical engineering.
基金the National Natural Science Foundation of China(Grant No.50578049)
文摘A throttling experiment for the multi-hole orifice (MO) using water was conducted based on the conclusion of key parameters affecting the MO throttling performance. Testing MOs and standard orifice plates (SOs) were designed for the throttling experiment to compare the throttling effect using the equivalent diameter ratio (RED) and diameter ratio (RD) as key parameters, respectively. Meanwhile, effective metrical conditions were provided for experimental accuracy. The throttling model form was determined according to the theoretical throttling model of SO. Then the unknown parameters involved were identified by experimental data. A good concordance between the modeling computation and experimental results shows a validation of the MO throtting model.
文摘A wind tunnel tests with different configurations,pitch and yaw angles were performed to study the wind load characteristics of the rigid model of the airship Zhiyuan-1. The rigid model was aimed to simulate a technical demonstrating stratospheric airship named Zhiyuan-1 according to the similarity principle of geometric and Reynolds number. Based on the results of wind tunnel test,the features of pressure coefficient distributions on the surface of the airship were described. It was indicated that the fins and the gondola of airship hardly have the effect on the pressure distribution on the surface of airship,but have obviously effect on the local areas near the fins and the gondola.
文摘This study explains the relationship between friction coefficient and pressure change at a range of Reynolds (21,056 - 28,574) and (0 - 1.4) solid loading ratio of two-phase flow (gas-solid) inside a circular copper pipe by using laboratory apparatus and solving the equations mathematically. An experimentally relationship of friction coefficient and pressure change with Reynolds number and flow velocity obtained also the relationship between the Solid loading ratio with friction coefficient and pressure change has been done for a Limit range of Reynolds number. It was noticed that the increase in friction coefficient and pressure change for two-phase flow was occurred when solid loading ratio increased. Also the relationship between pressure change and Reynolds number was direct proportion while the relationship between friction coefficient and Reynolds Number was inversely related.
文摘According the Coulomb earth pressure theory,it is obtained that,for normally consolidated soils,the lateral pressure coefficient of a soil at rest is equal to 1,and it is independent of the soil type,either granular or cohesive;or that the material is in a loose or compact state;hard or a soft cohesive soil.Also,a methodology to calculate the earth pressure for intermediate states between at rest condition and the active pressure is presented.In addition,a methodology to calculate the earth pressure for intermediate states between at rest condition and the passive pressure is presented.Two practical examples are presented:one for a frictionless wall;and another for a coarse wall.Practical recommendations are given for the use of the lateral earth pressure coefficient for different applications.