Catalytic C-H borylation is of prime topical importance,since easily available feedstock chemicals can thereby be transformed into valuable transient functional groups in the absence of directing groups.Herein,we disc...Catalytic C-H borylation is of prime topical importance,since easily available feedstock chemicals can thereby be transformed into valuable transient functional groups in the absence of directing groups.Herein,we disclose an iron-catalyzed C(sp^(3))-H borylation of simple,non-prefunctionalized alkanes,providing access to value-added products in a single step by means of photoelectrochemistry.The power of merging photo-and electrochemistry was mirrored by ample scope and exceedingly mild reaction conditions.Moreover,an outstanding position-selectivity in favor of primary C(sp^(3))-H proved viable within the photoelectrochemical borylation through a chemo-selective anodic overoxidation manifold.The ferro-photoelectrochemistry strategy avoids toxic precious transition metals,enabling C(sp^(3))-H borylations in a site-selective fashion.展开更多
基金the European Research Council(ERC Advanced Grantno.101021358)+2 种基金the Deutsche Forschungsgemeinschaft(DFG,Gottfried Wilhelm Leibniz award to L.A.)the Fonds der Chemischen Industrie(FCI,Kekulé-Fellowship to T.v.M.)the China Scholarship Council(CSC grant no.201906280067 to W.W.).
文摘Catalytic C-H borylation is of prime topical importance,since easily available feedstock chemicals can thereby be transformed into valuable transient functional groups in the absence of directing groups.Herein,we disclose an iron-catalyzed C(sp^(3))-H borylation of simple,non-prefunctionalized alkanes,providing access to value-added products in a single step by means of photoelectrochemistry.The power of merging photo-and electrochemistry was mirrored by ample scope and exceedingly mild reaction conditions.Moreover,an outstanding position-selectivity in favor of primary C(sp^(3))-H proved viable within the photoelectrochemical borylation through a chemo-selective anodic overoxidation manifold.The ferro-photoelectrochemistry strategy avoids toxic precious transition metals,enabling C(sp^(3))-H borylations in a site-selective fashion.
