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Distributed Nash Equilibrium Seeking Strategies Under Quantized Communication 被引量:2
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作者 Maojiao Ye Qing-Long Han +2 位作者 Lei Ding Shengyuan Xu Guobiao Jia 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第1期103-112,共10页
This paper is concerned with distributed Nash equi librium seeking strategies under quantized communication. In the proposed seeking strategy, a projection operator is synthesized with a gradient search method to achi... This paper is concerned with distributed Nash equi librium seeking strategies under quantized communication. In the proposed seeking strategy, a projection operator is synthesized with a gradient search method to achieve the optimization o players' objective functions while restricting their actions within required non-empty, convex and compact domains. In addition, a leader-following consensus protocol, in which quantized informa tion flows are utilized, is employed for information sharing among players. More specifically, logarithmic quantizers and uniform quantizers are investigated under both undirected and connected communication graphs and strongly connected digraphs, respec tively. Through Lyapunov stability analysis, it is shown that play ers' actions can be steered to a neighborhood of the Nash equilib rium with logarithmic and uniform quantizers, and the quanti fied convergence error depends on the parameter of the quan tizer for both undirected and directed cases. A numerical exam ple is given to verify the theoretical results. 展开更多
关键词 CONSENSUS distributed Nash equilibrium seeking projected gradient play quantized communication
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Equilibrium Strategy of the Pursuit-Evasion Game in Three-Dimensional Space 被引量:1
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作者 Nuo Chen Linjing Li Wenji Mao 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第2期446-458,共13页
The pursuit-evasion game models the strategic interaction among players, attracting attention in many realistic scenarios, such as missile guidance, unmanned aerial vehicles, and target defense. Existing studies mainl... The pursuit-evasion game models the strategic interaction among players, attracting attention in many realistic scenarios, such as missile guidance, unmanned aerial vehicles, and target defense. Existing studies mainly concentrate on the cooperative pursuit of multiple players in two-dimensional pursuit-evasion games. However, these approaches can hardly be applied to practical situations where players usually move in three-dimensional space with a three-degree-of-freedom control. In this paper,we make the first attempt to investigate the equilibrium strategy of the realistic pursuit-evasion game, in which the pursuer follows a three-degree-of-freedom control, and the evader moves freely. First, we describe the pursuer's three-degree-of-freedom control and the evader's relative coordinate. We then rigorously derive the equilibrium strategy by solving the retrogressive path equation according to the Hamilton-Jacobi-Bellman-Isaacs(HJBI) method, which divides the pursuit-evasion process into the navigation and acceleration phases. Besides, we analyze the maximum allowable speed for the pursuer to capture the evader successfully and provide the strategy with which the evader can escape when the pursuer's speed exceeds the threshold. We further conduct comparison tests with various unilateral deviations to verify that the proposed strategy forms a Nash equilibrium. 展开更多
关键词 Differential game equilibrium strategy pursuit-evasion game threedegree-of-freedom control
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Magnetopause properties at the dusk magnetospheric flank from global magnetohydrodynamic simulations,the kinetic Vlasov equilibrium,and in situ observations--Potential implications for SMILE 被引量:1
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作者 Marius Echim Costel Munteanu +1 位作者 Gabriel Voitcu Eliza Teodorescu 《Earth and Planetary Physics》 EI CSCD 2024年第1期222-233,共12页
We derived the properties of the terrestrial magnetopause(MP)from two modeling approaches,one global–fluid,the other local–kinetic,and compared the results with data collected in situ by the Magnetospheric Multiscal... We derived the properties of the terrestrial magnetopause(MP)from two modeling approaches,one global–fluid,the other local–kinetic,and compared the results with data collected in situ by the Magnetospheric Multiscale 2(MMS2)spacecraft.We used global magnetohydrodynamic(MHD)simulations of the Earth’s magnetosphere(publicly available from the NASA-CCMC[National Aeronautics and Space Administration–Community Coordinated Modeling Center])and local Vlasov equilibrium models(based on kinetic models for tangential discontinuities)to extract spatial profiles of the plasma and field variables at the Earth’s MP.The global MHD simulations used initial solar wind conditions extracted from the OMNI database at the time epoch when the MMS2 observes the MP.The kinetic Vlasov model used asymptotic boundary conditions derived from the same in situ MMS measurements upstream or downstream of the MP.The global MHD simulations provide a three-dimensional image of the magnetosphere at the time when the MMS2 crosses the MP.The Vlasov model provides a one-dimensional local view of the MP derived from first principles of kinetic theory.The MMS2 experimental data also serve as a reference for comparing and validating the numerical simulations and modeling.We found that the MP transition layer formed in global MHD simulations was generally localized closer to the Earth(roughly by one Earth radius)from the position of the real MP observed by the MMS.We also found that the global MHD simulations overestimated the thickness of the MP transition by one order of magnitude for three analyzed variables:magnetic field,density,and tangential speed.The MP thickness derived from the local Vlasov equilibrium was consistent with observations for all three of these variables.The overestimation of density in the Vlasov equilibrium was reduced compared with the global MHD solutions.We discuss our results in the context of future SMILE(Solar wind Magnetosphere Ionosphere Link Explorer)campaigns for observing the Earth’s MP. 展开更多
关键词 MAGNETOPAUSE magnetohydrodynamic numerical simulations Vlasov equilibrium Magnetospheric Multiscale observations
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Numerical analysis for the free-boundary current reversal equilibrium in the AC plasma current operation in a tokamak
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作者 胡业民 王柳青 +2 位作者 白书航 于治 夏天阳 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第2期22-30,共9页
In recent decades, tokamak discharges with zero total toroidal current have been reported in tokamak experiments, and this is one of the key problems in alternating current(AC) operations.An efficient free-boundary eq... In recent decades, tokamak discharges with zero total toroidal current have been reported in tokamak experiments, and this is one of the key problems in alternating current(AC) operations.An efficient free-boundary equilibrium code is developed to investigate such advanced tokamak discharges with current reversal equilibrium configuration. The calculation results show that the reversal current equilibrium can maintain finite pressure and also has considerable effects on the position of the X-point and the magnetic separatrix shape, and hence also on the position of the strike point on the divertor plates, which is extremely useful for magnetic design, MHD stability analysis, and experimental data analysis etc. for the AC plasma current operation on tokamaks. 展开更多
关键词 current reversal equilibrium AC operation free-boundary equilibrium TOKAMAK
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Kinetic equilibrium reconstruction with internal safety factor profile constraints on EAST tokamak
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作者 樊皓尘 李国强 +10 位作者 钱金平 张学习 邬潇河 储宇奇 朱翔 连辉 刘海庆 吕波 金仡飞 臧庆 黄佳 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第4期61-67,共7页
Reconstruction of plasma equilibrium plays an important role in the analysis and simulation of plasma experiments. The kinetic equilibrium reconstruction with pressure and edge current constraints has been employed on... Reconstruction of plasma equilibrium plays an important role in the analysis and simulation of plasma experiments. The kinetic equilibrium reconstruction with pressure and edge current constraints has been employed on EAST tokamak. However, the internal safety factor(q) profile is not accurate. This paper proposes a new way of incorporating q profile constraints into kinetic equilibrium reconstruction. The q profile is yielded from the Polarimeter Interferometer(POINT)reconstruction. Virtual probes containing information on q profile constraints are added to inputs of the kinetic equilibrium reconstruction program to obtain the final equilibrium. The new equilibrium produces a more accurate internal q profile. This improved method would help analyze EAST experiments. 展开更多
关键词 equilibrium reconstruction tokamak data analysis kinetic equilibrium q profile polarimeter-interferometer
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Effects of ionic liquids on the vapor-liquid equilibrium of 1,3,5-trioxane-water system at 101.3 kPa
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作者 Fei Li Tao Zhang +3 位作者 Li Lv Wenxiang Tang Yan Wang Shengwei Tang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第9期42-50,共9页
Increasing the 1,3,5-trioxane(TOX) concentration in the equilibrated vapor phase of TOX-H_(2)O system has been recognized as a challenge for the azeotrope. Ionic liquids(ILs) were used to improve the relative volatili... Increasing the 1,3,5-trioxane(TOX) concentration in the equilibrated vapor phase of TOX-H_(2)O system has been recognized as a challenge for the azeotrope. Ionic liquids(ILs) were used to improve the relative volatility of TOX to H_(2)O and destroy the azeotrope in the TOX-H2O system. The vapor-liquid equilibrium of TOX-H2O system at 101.3 kPa was studied with the addition of 1-butyl-3-methylimidazolium hydrogen sulfate, 1-hexyl-3-methylimidazolium hydrogen sulfate and 1-butyl-3-methylimidazolium nitrate, respectively. The results showed that the volatility of TOX increased with the increase in IL dosage. And the volatility of water decreased with the increase in IL dosage. The relative volatility of TOX to H_(2)O was improved with the increase in ILs dosage. The azeotrope could be destroyed with an IL mole fraction of about 0.10. A non-random two-liquid(NRTL) model was successfully used to correlate the experimental data. The interaction parameters were obtained by fitting the experimental data with the model. The results indicated that a strong interaction existed between ILs and water. The strong interaction improved the volatility of TOX and inhibited the volatility of water, and then intensified the relative volatility of TOX to H_(2)O. The results showed that an ILs with strong polarity and hydrophilicity may be a potential additive to improve the TOX concentration in the equilibrated vapor phase. 展开更多
关键词 1 3 5-Trioxane Vaporeliquid equilibrium Ionic liquids NRTL model
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Assessment of Liver Fibrosis in HBsAg-Negative and Anti HBc Positive Patients
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作者 Kounpiélimé Sosthène Somda Aboubacar Coulibaly +4 位作者 Oyétoundé Taofick Amanda Sandrine Marie Odile Soudre Lawagoulé Joseph Emile Ky Christiane Bere Arsène Roger Sombie 《Open Journal of Gastroenterology》 CAS 2024年第10期331-339,共9页
Background: Surface antigen (HBsAg) is the mean marker of hepatitis B virus infection. During the course of the infection, some patients lose the HBsAg and only the presence of anti-HBc antibody indicates previous con... Background: Surface antigen (HBsAg) is the mean marker of hepatitis B virus infection. During the course of the infection, some patients lose the HBsAg and only the presence of anti-HBc antibody indicates previous contact with the virus. Among these patients, some have detectable viral load (occult infection) but most without viral replication. There is no guideline regarding these patients. The aim of this study was to assess hepatic fibrosis in patients with only the hepatitis B virus contact marker “total anti-HBc”. Patients and methods: it was a descriptive and analytical cross-sectional study, conducted in three private hospitals from January to August 2022. Were included HBsAg-negative and HBc-positive patients, consulting in Gastroenterology departments. Noninvasive methods (APRI, FIB-4 and FIBROSCAN) were used to evaluate liver stiffness because of their easy accessibility and low-cost. The hepatic fibrosis was considered significant when the score determined by APRI, FIB-4 and FIBROSCAN® tests was respectively greater than 1.5;2.67 and 8 kPa corresponding to fibrosis level 2 (F2). Results: A total of 63 HBsAg-negative/total HBcAg-positive patients were included. The mean age was 49.9 ± 13.4 years. The male/female sex ratio was 1.78. Of the 63 patients, 19 had significant liver fibrosis (30.1%) among which 9 patients had HCC. The FIB-4 score outperformed the APRI score in assessing liver fibrosis, with a sensitivity of 84.2%, a specificity of 100% and a negative predictive value of 93.6%. In univariate analysis, there was a significant association between the occurrence of significant liver fibrosis and age over 40 years, dyslipidaemia, obesity, alcohol consumption, smoking, herbal medicine, negative anti-HBs immunological status and detectable viral load. Conclusion: Our study revealed a high prevalence of significant to severe hepatic fibrosis in anti-HBc positive patients. In most of the cases, the fibrosis was severe. Progression to HCC has also been possible. There is no consensus on the follow-up strategy for those patients. However, screening for hepatic fibrosis using noninvasive methods should be recommended for patients aged over 40 years, alcohol or herbal medicine users, patients with metabolic syndrome or occult hepatitis B. In HBsAg-negative/anti-HBc-positive patients, liver stiffness should be evaluated and if it is greater than F2, HCC screening should be started. 展开更多
关键词 Anti HBc positives Liver Fibrosis Sub-Saharan Hepatitis B Virus
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Phase equilibrium data prediction and process optimizationin butadiene extraction process
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作者 Baowei Niu Yanjie Yi +5 位作者 Yuwen Wei Fuzhen Zhang Lili Wang Li Xia Xiaoyan Sun Shuguang Xiang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2024年第7期1-12,共12页
In response to the lack of reliable physical parameters in the process simulation of the butadiene extraction,a large amount of phase equilibrium data were collected in the context of the actual process of butadiene p... In response to the lack of reliable physical parameters in the process simulation of the butadiene extraction,a large amount of phase equilibrium data were collected in the context of the actual process of butadiene production by acetonitrile.The accuracy of five prediction methods,UNIFAC(UNIQUAC Functional-group Activity Coefficients),UNIFAC-LL,UNIFAC-LBY,UNIFAC-DMD and COSMO-RS,applied to the butadiene extraction process was verified using partial phase equilibrium data.The results showed that the UNIFAC-DMD method had the highest accuracy in predicting phase equilibrium data for the missing system.COSMO-RS-predicted multiple systems showed good accuracy,and a large number of missing phase equilibrium data were estimated using the UNIFAC-DMD method and COSMO-RS method.The predicted phase equilibrium data were checked for consistency.The NRTL-RK(non-Random Two Liquid-Redlich-Kwong Equation of State)and UNIQUAC thermodynamic models were used to correlate the phase equilibrium data.Industrial device simulations were used to verify the accuracy of the thermodynamic model applied to the butadiene extraction process.The simulation results showed that the average deviations of the simulated results using the correlated thermodynamic model from the actual values were less than 2%compared to that using the commercial simulation software,Aspen Plus and its database.The average deviation was much smaller than that of the simulations using the Aspen Plus database(>10%),indicating that the obtained phase equilibrium data are highly accurate and reliable.The best phase equilibrium data and thermodynamic model parameters for butadiene extraction are provided.This improves the accuracy and reliability of the design,optimization and control of the process,and provides a basis and guarantee for developing a more environmentally friendly and economical butadiene extraction process. 展开更多
关键词 Butadiene extraction Phase equilibrium data Prediction methods Thermodynamic modeling Process simulation
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Multi-Objective Equilibrium Optimizer for Feature Selection in High-Dimensional English Speech Emotion Recognition
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作者 Liya Yue Pei Hu +1 位作者 Shu-Chuan Chu Jeng-Shyang Pan 《Computers, Materials & Continua》 SCIE EI 2024年第2期1957-1975,共19页
Speech emotion recognition(SER)uses acoustic analysis to find features for emotion recognition and examines variations in voice that are caused by emotions.The number of features acquired with acoustic analysis is ext... Speech emotion recognition(SER)uses acoustic analysis to find features for emotion recognition and examines variations in voice that are caused by emotions.The number of features acquired with acoustic analysis is extremely high,so we introduce a hybrid filter-wrapper feature selection algorithm based on an improved equilibrium optimizer for constructing an emotion recognition system.The proposed algorithm implements multi-objective emotion recognition with the minimum number of selected features and maximum accuracy.First,we use the information gain and Fisher Score to sort the features extracted from signals.Then,we employ a multi-objective ranking method to evaluate these features and assign different importance to them.Features with high rankings have a large probability of being selected.Finally,we propose a repair strategy to address the problem of duplicate solutions in multi-objective feature selection,which can improve the diversity of solutions and avoid falling into local traps.Using random forest and K-nearest neighbor classifiers,four English speech emotion datasets are employed to test the proposed algorithm(MBEO)as well as other multi-objective emotion identification techniques.The results illustrate that it performs well in inverted generational distance,hypervolume,Pareto solutions,and execution time,and MBEO is appropriate for high-dimensional English SER. 展开更多
关键词 Speech emotion recognition filter-wrapper HIGH-DIMENSIONAL feature selection equilibrium optimizer MULTI-OBJECTIVE
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Influence of joint spacing and rock characteristics on the toppling stability of cut rock slope through a simplified limit equilibrium method
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作者 ZHANG Xue-peng JIANG Yu-jing +6 位作者 DU Yan WANG Ke-peng CAI Yue WANG Xing-da SU Hang GOLSANAMI Naser LIU Bao-guo 《Journal of Central South University》 SCIE EI CAS CSCD 2024年第8期2694-2702,共9页
Toppling failure of rock mass/soil slope is an important geological and environmental problem.Clarifying its failure mechanism under different conditions has great significance in engineering.The toppling failure of a... Toppling failure of rock mass/soil slope is an important geological and environmental problem.Clarifying its failure mechanism under different conditions has great significance in engineering.The toppling failure of a cutting slope occurred in a hydropower station in Kyushu,Japan illustrates that the joint characteristic played a significant role in the occurrence of rock slope tipping failure.Thus,in order to consider the mechanical properties of jointed rock mass and the influence of geometric conditions,a simplified analytical approach based on the limit equilibrium method for modeling the flexural toppling of cut rock slopes is proposed to consider the influence of the mechanical properties and geometry condition of jointed rock mass.The theoretical solution is compared with the numerical solution taking Kyushu Hydropower Station in Japan as one case,and it is found that the theoretical solution obtained by the simplified analysis method is consistent with the numerical analytical solution,thus verifying the accuracy of the simplified method.Meanwhile,the Goodman-Bray approach conventionally used in engineering practice is improved according to the analytical results.The results show that the allowable slope angle may be obtained by the improved Goodman-Bray approach considering the joint spacing,the joint frictional angle and the tensile strength of rock mass together. 展开更多
关键词 slope stability flexural toppling rock slope simplified limit equilibrium method
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Magnetic diagnostics layout design for CFETR plasma equilibrium reconstruction
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作者 于庆泽 黄耀 +6 位作者 罗正平 汪悦航 刘自结 芮望颐 吴凯 肖炳甲 李建刚 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第4期537-543,共7页
Plasma equilibrium reconstruction provides essential information for tokamak operation and physical analysis.An extensive and reliable set of magnetic diagnostics is required to obtain accurate plasma equilibrium.This... Plasma equilibrium reconstruction provides essential information for tokamak operation and physical analysis.An extensive and reliable set of magnetic diagnostics is required to obtain accurate plasma equilibrium.This study designs and optimizes the magnetic diagnostics layout for the reconstruction of the equilibrium of the plasma according to the scientific objectives,engineering design parameters,and limitations of the Chinese Fusion Engineering Test Reactor(CFETR).Based on the CFETR discharge simulation,magnetic measurement data are employed to reconstruct consistent plasma equilibrium parameters,and magnetic diagnostics'number and position are optimized by truncated Singular value decomposition,verifying the redundancy reliability of the magnetic diagnostics layout design.This provides a design solution for the layout of the magnetic diagnostics system required to control the plasma equilibrium of CFETR,and the developed design and optimization method can provide effective support to design magnetic diagnostics systems for future magnetic confinement fusion devices. 展开更多
关键词 plasma equilibrium reconstruction EFIT code flux loops and magnetic probes optimization
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Intrinsic correlation between the generalized phase equilibrium condition and mechanical behaviors in hydrate-bearing sediments
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作者 Jiazuo Zhou Changfu Wei +2 位作者 Rongtao Yan Yuan Zhou Yi Dong 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第7期2822-2832,共11页
The phase equilibrium and mechanical behaviors of natural gas hydrate-bearing sediment are essential for gas recovery from hydrate reservoirs.In heating closed systems,the temperature-pressure path of hydrate-bearing ... The phase equilibrium and mechanical behaviors of natural gas hydrate-bearing sediment are essential for gas recovery from hydrate reservoirs.In heating closed systems,the temperature-pressure path of hydrate-bearing sediment deviates from that of pure bulk hydrate,reflecting the porous media effect in phase equilibrium.A generalized phase equilibrium equation was established for hydrate-bearing sediments,which indicates that both capillary and osmotic pressures cause the phase equilibrium curve to shift leftward on the temperature-pressure plane.In contrast to bulk hydrate,hydrate-bearing sediment always contains a certain amount of unhydrated water,which keeps phase equilibrium with the hydrate within the hydrate stability field.With changes in temperature and pressure,a portion of pore hydrate and unhydrated water may transform into each other,affecting the shear strength of hydrate-bearing sediment.A shear strength model is proposed to consider not only hydrate saturation but also the change in temperature and pressure of hydrate-bearing sediment.The model is validated by experimental data with various hydrate saturation,temperature and pressure conditions.The deformation induced by partial dissociation was studied through depressurization tests under constant effective stress.The reduction in gas pressure within the hydrate stability field indeed caused sediment deformation.The dissociation-induced deformation can be reasonably estimated as the difference in volume between hydrate-bearing and hydrate-free sediments from the compression curves. 展开更多
关键词 Hydrate-bearing sediment Generalized phase equilibrium Unhydrated water Partial dissociation Mechanical behavior
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Probabilistic Analysis of Slope Using Finite Element Approach and Limit Equilibrium Approach around Amalpata Landslide of West Central, Nepal
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作者 Mahendra Acharya Khomendra Bhandari +2 位作者 Sandesh Dhakal Aasish Giri Prabin Kafle 《International Journal of Geosciences》 CAS 2024年第5期416-432,共17页
The stability study of the ongoing and recurring Amalpata landslide in Baglung in Nepal’s Gandaki Province is presented in this research. The impacted slope is around 200 meters high, with two terraces that have diff... The stability study of the ongoing and recurring Amalpata landslide in Baglung in Nepal’s Gandaki Province is presented in this research. The impacted slope is around 200 meters high, with two terraces that have different slope inclinations. The lower bench, located above the basement, consistently fails and sets others up for failure. The fluctuating water level of the slope, which travels down the slope masses, exacerbates the slide problem. The majority of these rocks are Amalpata landslide area experiences several structural disruptions. The area’s stability must be evaluated in order to prevent and control more harm from occurring to the nearby agricultural land and people living along the slope. The slopes’ failures increase the damages of house existing in nearby area and the erosion of the slope. Two modeling techniques the finite element approach and the limit equilibrium method were used to simulate the slope. The findings show that, in every case, the terrace above the basement is where the majority of the stress is concentrated, with a safety factor of near unity. Using probabilistic slope stability analysis, the failure probability was predicted to be between 98.90% and 100%. 展开更多
关键词 Finite Element Approach Limit equilibrium Method SLOPE Factor of Safety
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Embedding Perovskite in Polymer Matrix Achieved Positive Temperature Response with Inversed Temperature Crystallization
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作者 Meiting Peng Xue Guan +10 位作者 Yingzhu Wu Nan Zhang Qi Feng Liyong Tian Yancheng Wu Yangfan Zhang Feng Gan Fuqin Deng Meilin Huang Guichuan Xing Ningbo Yi 《Energy & Environmental Materials》 SCIE EI CAS CSCD 2024年第5期357-367,共11页
Organic perovskites are promising semiconductor materials for advanced photoelectric applications.Their fluorescence typically shows a negative temperature coefficient due to bandgap change and structural instability.... Organic perovskites are promising semiconductor materials for advanced photoelectric applications.Their fluorescence typically shows a negative temperature coefficient due to bandgap change and structural instability.In this study,a novel perovskite-based composite with positive sensitivity to temperature was designed and obtained based on its inverse temperature crystallization,demonstrating good flexibility and solution processability.The supercritical drying method was used to address the limitations of annealing drying in preparing high-performance perovskite.Optimizing the precursor composition proved to be an effective approach for achieving high fluorescence and structural integrity in the perovskite material.This perovskite-based composite exhibited a positive temperature sensitivity of 28.563%℃^(-1)for intensity change and excellent temperature cycling reversibility in the range of 25-40℃in an ambient environment.This made it suitable for use as a smart window with rapid response.Furthermore,the perovskite composite was found to offer temperature-sensing photoluminescence and flexible processability due to its components of perovskite-based compounds and polyethylene oxide.The organic precursor solvent could be a promising candidate for use as ink to print or write on various substrates for optoelectronic devices responding to temperature. 展开更多
关键词 FLEXIBILITY inversed temperature crystallization PEROVSKITE positive temperature response
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Amplifying colorectal cancer progression: impact of a PDIA4/SP1 positive feedback loop by circPDIA4 sponging miR-9-5p
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作者 Yan Zhuang Yiding Ai +6 位作者 Peng Li Xin Yue Yue Li Luling Shan Tongtong Wang Peng Zhao Xun Jin 《Cancer Biology & Medicine》 SCIE CAS CSCD 2024年第10期916-933,共18页
Objective:Colorectal cancer(CRC)is a prevalent malignant tumor with a high fatality rate.CircPDIA4 has been shown to have a vital role in cancer development by acting as a facilitator.Nevertheless,the impact of the ci... Objective:Colorectal cancer(CRC)is a prevalent malignant tumor with a high fatality rate.CircPDIA4 has been shown to have a vital role in cancer development by acting as a facilitator.Nevertheless,the impact of the circPDIA4/miR-9-5p/SP1 axis on development of CRC has not been studied.Methods:Western blot,immunohistochemistry,and reverse transcription-quantitative polymerase chain reaction assays were used to analyze gene expression.The CCK-8 assay was used to assess cell growth.The Transwell assay was used to detect invasion and migration of cells.The luciferase reporter and RNA immunoprecipitation tests were used to determine if miR-9-5p and circPDIA4(or SP1)bind to one another.An in vivo assay was used to measure tumor growth.Results:It was shown that circPDIA4 expression was greater in CRC cell lines and tissues than healthy cell lines and tissues.CircPDIA4 knockdown prevented the invasion,migration,and proliferation of cells in CRC.Additionally,the combination of circPDIA4 and miR-9-5p was confirmed,as well as miR-9-5p binding to SP1.Rescue experiments also showed that the circPDIA4/miR-9-5p/SP1 axis accelerated the development of CRC.In addition,SP1 combined with the promoter region of circPDIA4 and induced circPDIA4 transcription.CircPDIA4 was shown to facilitate tumor growth in an in vivo assay.Conclusions:The circPDIA4/miR-9-5p/SP1 feedback loop was shown to aggravate CRC progression.This finding suggests that the ceRNA axis may be a promising biomarker for CRC patient treatment. 展开更多
关键词 CircRNA positive feedback loop colorectal cancer PDIA4 SP1
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Equilibrium reconstruction method for self-organized plasmas on reversed field pinches with polarimeter-interferometer
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作者 Yuhua HUANG Ke LIU +17 位作者 Wenzhe MAO Caoxiang ZHU Tao LAN Yiming ZU Yongkang ZHOU Xingkang WANG Peng DENG Li WANG Pai PENG Adi LIU Chu ZHOU Haifeng LIU Hong LI Jinlin XIE Yuhong XU Weixing DING Wandong LIU Ge ZHUANG 《Plasma Science and Technology》 SCIE EI CAS CSCD 2024年第12期31-40,共10页
In the reversed field pinch(RFP),plasmas exhibit various self-organized states.Among these,the three-dimensional(3D)helical state known as the“quasi-single-helical”(QSH)state enhances RFP confinement.However,accurat... In the reversed field pinch(RFP),plasmas exhibit various self-organized states.Among these,the three-dimensional(3D)helical state known as the“quasi-single-helical”(QSH)state enhances RFP confinement.However,accurately describing the equilibrium is challenging due to the presence of 3D structures,magnetic islands,and chaotic regions.It is difficult to obtain a balance between the available diagnostic and the real equilibrium structure.To address this issue,we introduce KTX3DFit,a new 3D equilibrium reconstruction code specifically designed for the Keda Torus eXperiment(KTX)RFP.KTX3DFit utilizes the stepped-pressure equilibrium code(SPEC)to compute 3D equilibria and uses polarimetric interferometer signals from experiments.KTX3DFit is able to reconstruct equilibria in various states,including axisymmetric,doubleaxis helical(DAx),and single-helical-axis(SHAx)states.Notably,this study marks the first integration of the SPEC code with internal magnetic field data for equilibrium reconstruction and could be used for other 3D configurations. 展开更多
关键词 equilibrium reconstruction polarimeter-interferometer multi-region relaxed MHD 3D self-organized states reversed field pinch
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Positive health:An integrated quantitative approach in patients with chronic gastrointestinal and hepato-pancreatico-biliary disorders
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作者 Anja H W M Lemlijn-Slenter Karolina AP Wijnands +4 位作者 Gijs van der Hamsvoort Luuk P van Iperen Nico Wolter Angelique E de Rijk Ad AM Masclee 《World Journal of Gastroenterology》 SCIE CAS 2024年第28期3418-3427,共10页
BACKGROUND The concept of positive health(PH)supports an integrated approach for patients by taking into account six dimensions of health.This approach is especially relevant for patients with chronic disorders.Chroni... BACKGROUND The concept of positive health(PH)supports an integrated approach for patients by taking into account six dimensions of health.This approach is especially relevant for patients with chronic disorders.Chronic gastrointestinal and hepatopancreatico-biliary(GI-HPB)disorders are among the top-6 of the most prevalent chronically affected organ systems.The impact of chronic GI-HPB disorders on individuals may be disproportionally high because:(1)The affected organ system frequently contributes to a malnourished state;and(2)persons with chronic GIHPB disorders are often younger than persons with chronic diseases in other organ systems.AIM To describe and quantify the dimensions of PH in patients with chronic GI-HPB disorders.METHODS Prospective,observational questionnaire study performed between 2019 and 2021 in 235 patients with a chronic GIHPB disorder attending the Outpatient Department of the Maastricht University Medical Center.Validated questionnaires and data from patient files were used to quantify the six dimensions of PH.Internal consistency was tested with McDonald’s Omega.Zero-order Pearson correlations and t-tests were used to assess associations and differences.A P value<0.05 was considered significant.RESULTS The GI-HPB patients scored significantly worse in all dimensions of PH compared to control data or norm scores from the general population.Regarding quality of life,participation and daily functioning,GI-HPB patients scored in the same range as patients with chronic disorders in other organ systems,but depressive symptoms(in 35%)and malnutrition(in 45%)were more frequent in patients with chronic GI-HPB disorders.Intercorrelation scores between the six dimensions were only very weak to weak,forcing us to quantify each domain separately.CONCLUSION All six dimensions of PH are impaired in the GI-HPB patients.Malnutrition and depressive symptoms are more prevalent compared to patients with chronic disorders in other organ systems. 展开更多
关键词 positive health Chronic gut disorders Gastrointestinal disorders Hepato-pancreatico-biliary disorders Integrated care
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Predictive value of positive lymph node ratio in patients with locally advanced gastric remnant cancer
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作者 Meng Zhuo Lei Tian +3 位作者 Ting Han Teng-Fei Liu Xiao-Lin Lin Xiu-Ying Xiao 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第3期833-843,共11页
BACKGROUND Traditional lymph node stage(N stage)has limitations in advanced gastric remnant cancer(GRC)patients;therefore,establishing a new predictive stage is necessary.AIM To explore the predictive value of positiv... BACKGROUND Traditional lymph node stage(N stage)has limitations in advanced gastric remnant cancer(GRC)patients;therefore,establishing a new predictive stage is necessary.AIM To explore the predictive value of positive lymph node ratio(LNR)according to clinicopathological characteristics and prognosis of locally advanced GRC.METHODS Seventy-four patients who underwent radical gastrectomy and lymphadenectomy for locally advanced GRC were retrospectively reviewed.The relationship between LNR and clinicopathological characteristics was analyzed.The survival analysis was performed using Kaplan-Meier survival curves and Cox regression model.RESULTS Number of metastatic LNs,tumor diameter,depth of tumor invasion,Borrmann type,serum tumor biomarkers,and tumor-node-metastasis(TNM)stage were correlated with LNR stage and N stage.Univariate analysis revealed that the factors affecting survival included tumor diameter,anemia,serum tumor biomarkers,vascular or neural invasion,combined resection,LNR stage,N stage,and TNM stage(all P<0.05).The median survival time for those with LNR0,LNR1,LNR2 and LNR3 stage were 61,31,23 and 17 mo,respectively,and the differences were significant(P=0.000).Anemia,tumor biomarkers and LNR stage were independent prognostic factors for survival in multivariable analysis(all P<0.05).CONCLUSION The new LNR stage is uniquely based on number of metastatic LNs,with significant prognostic value for locally advanced GRC,and could better differentiate overall survival,compared with N stage. 展开更多
关键词 Gastric remnant cancer positive lymph node ratio Clinicopathological characteristics PROGNOSIS
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Enhanced Hybrid Equilibrium Strategy in Fog-Cloud Computing Networks with Optimal Task Scheduling
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作者 Muchang Rao Hang Qin 《Computers, Materials & Continua》 SCIE EI 2024年第5期2647-2672,共26页
More devices in the Intelligent Internet of Things(AIoT)result in an increased number of tasks that require low latency and real-time responsiveness,leading to an increased demand for computational resources.Cloud com... More devices in the Intelligent Internet of Things(AIoT)result in an increased number of tasks that require low latency and real-time responsiveness,leading to an increased demand for computational resources.Cloud computing’s low-latency performance issues in AIoT scenarios have led researchers to explore fog computing as a complementary extension.However,the effective allocation of resources for task execution within fog environments,characterized by limitations and heterogeneity in computational resources,remains a formidable challenge.To tackle this challenge,in this study,we integrate fog computing and cloud computing.We begin by establishing a fog-cloud environment framework,followed by the formulation of a mathematical model for task scheduling.Lastly,we introduce an enhanced hybrid Equilibrium Optimizer(EHEO)tailored for AIoT task scheduling.The overarching objective is to decrease both the makespan and energy consumption of the fog-cloud system while accounting for task deadlines.The proposed EHEO method undergoes a thorough evaluation against multiple benchmark algorithms,encompassing metrics likemakespan,total energy consumption,success rate,and average waiting time.Comprehensive experimental results unequivocally demonstrate the superior performance of EHEO across all assessed metrics.Notably,in the most favorable conditions,EHEO significantly diminishes both the makespan and energy consumption by approximately 50%and 35.5%,respectively,compared to the secondbest performing approach,which affirms its efficacy in advancing the efficiency of AIoT task scheduling within fog-cloud networks. 展开更多
关键词 Artificial intelligence of things fog computing task scheduling equilibrium optimizer differential evaluation algorithm local search
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Lithium-Ion Battery Pack Based on Fuzzy Logic Control Research on Multi-Layer Equilibrium Circuits
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作者 Tiezhou Wu Yukan Zhang 《Energy Engineering》 EI 2024年第8期2231-2255,共25页
In order to solve the problem of inconsistent energy in the charging and discharging cycles of lithium-ion battery packs,a new multilayer equilibrium topology is designed in this paper.The structure adopts a hierarchi... In order to solve the problem of inconsistent energy in the charging and discharging cycles of lithium-ion battery packs,a new multilayer equilibrium topology is designed in this paper.The structure adopts a hierarchical structure design,which includes intra-group equilibrium,primary inter-group equilibrium and secondary inter-group equilibrium.This structure greatly increases the number of equilibrium paths for lithium-ion batteries,thus shortening the time required for equilibrium,and improving the overall efficiency.In terms of control strategy,fuzzy logic control(FLC)is chosen to control the size of the equilibrium current during the equilibrium process.We performed rigorous modeling and simulation of the proposed system by MATLAB and Simulink software.Experiments show that the multilayer equilibrium circuit structure greatly exceeds the traditional single-layer equilibrium circuit in terms of efficacy,specifically,the Li-ion battery equilibrium speed is improved by 12.71%in static equilibrium,14.48%in charge equilibrium,and 11.19%in discharge equilibrium.In addition,compared with the maximum value algorithm,the use of the FLC algorithm reduces the equalization time by about 3.27%and improves the energy transfer efficiency by about 66.49%under the stationary condition,which verifies the feasibility of the equalization scheme. 展开更多
关键词 Lithium-ion battery for new energy vehicles lithium-ion battery equilibrium fuzzy logic control
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