Acupuncture at Fengchi（GB20） in the posterior neck improves vertigo.However,subarachnoid hemorrhage and spinal epidural hematoma have been reported to occur after acupuncture in the posterior neck.Therefore,in the p...Acupuncture at Fengchi（GB20） in the posterior neck improves vertigo.However,subarachnoid hemorrhage and spinal epidural hematoma have been reported to occur after acupuncture in the posterior neck.Therefore,in the present study,we assessed the safety of acupuncture at Fengchi.Laboratory tests and adverse event reports were used to evaluate the safety of different acupuncture manipulations for the treatment of posterior circulation ischemia with vertigo.A total of 136 patients were randomly assigned to four groups.Verum acupuncture was conducted with different needle insertion directions（contralateral paropia or prominentia laryngea） and different needle twisting frequencies（60 or 120 times/minute） at Fengchi and matching acupoints（for example,Zhongwan [CV12],Qihai [CV6],Zusanli [ST36],and Fenglong [ST40]）.The patients received 14 treatments over 3–4 weeks.Routine blood analysis,hepatic and renal function tests,urine and feces tests and electrocardiography were performed before the first treatment session and after the final session.Adverse events were recorded after every session.Of the 136 patients,120 completed the study.There were no significant differences between pretreatment and posttreatment test results in any of the groups.Only five patients suffered from minor adverse events（needling pain,slight hematoma and transient chest tightness）.No serious adverse events were found.Our results indicate that a 14-session course of needling at Fengchi is relatively safe for treating posterior circulation ischemia with vertigo.展开更多
Objective:To understand the clinical characteristics of patients with embryonic posterior cerebral artery and its correlation with abnormal vascular development.Methods:The clinical data of 396 patients with embryonic...Objective:To understand the clinical characteristics of patients with embryonic posterior cerebral artery and its correlation with abnormal vascular development.Methods:The clinical data of 396 patients with embryonic posterior cerebral artery confirmed by magnetic resonance angiography(MRA)and computed tomography angiography(CTA)were analyzed.Results:Two-hundred patients had clinical manifestations of posterior circulation ischemia,including recurrent dizziness,vertigo,and tinnitus;45 had headaches,97 had limb weakness,and 16 patients had syncope or impaired consciousness.Seventy-six patients with circulatory infarction were admitted to the hospital.There were 251 patients with history of hypertension,74 with diabetes,113 with hyperlipidemia,13 with dominant vertebral artery,10 with intracranial aneurysm,and 19 with absence of A1 segment of the anterior cerebral artery(considering developmental variation).Conclusion:Embryonic posterior cerebral artery develops abnormally during the embryonic period,often accompanied by abnormal vascular access.Due to abnormal hemodynamics,the incidence of posterior circulation ischemia,aneurysm,and infarction increases in such patients.展开更多
目的探讨老年后循环缺血性卒中患者预后及危险因素。方法选取河北省承德市中心医院老年后循环缺血性卒中患者120例,根据治疗后3个月预后情况进行分组,分析预后不良和良好患者临床一般资料、外周血空腹血糖、糖化血红蛋白(hemoglobin A_(...目的探讨老年后循环缺血性卒中患者预后及危险因素。方法选取河北省承德市中心医院老年后循环缺血性卒中患者120例,根据治疗后3个月预后情况进行分组,分析预后不良和良好患者临床一般资料、外周血空腹血糖、糖化血红蛋白(hemoglobin A_(1)c,HbA_(1)c)等差异,总结老年后循环缺血性卒中患者预后的影响因素。结果预后不良患者39例,预后不良发生率为32.50%。预后不良组年龄和入院期间最高美国国立卫生研究所卒中量表(National Institute of Health Stroke Scale,NIHSS)评分分别为(68.93±4.02)岁和(19.30±2.50)分,高于预后良好组(P<0.05)。预后不良组空腹血糖、HbA_(1)c、脂蛋白相关磷脂酶a2(lipoprotein associated phospholipase A2,LP-PLA2)、超敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP)和血小板活化因子(platelet activating factor,PAF)分别为(7.28±0.92)mmol/L、(7.02±0.86)%、(330.50±65.53)μg/L、(20.22±6.43)ng/L和(248.23±44.18)ng/L,高于预后良好组(P<0.05)。Logistic回归分析,显示年龄、入院期间最高NIHSS评分、空腹血糖、LP-PLA2、PAF是患者预后的影响因素(P<0.05)。构建的方程预测预后不良的ROC曲线下面积为0.884(95%CI:0.821~0.948),P<0.05,敏感度和特异度分别为84.60%和81.50%。结论老年后循环缺血性卒中患者预后不良比例高,预后情况受患者年龄、入院期间最高NIHSS评分、空腹血糖、LP-PLA2、PAF的影响,同时由此构建的模型对患者预后不良具有较高的预测价值。展开更多
基金supported by the National Basic Research Program of China(973 Program),No.2010CB530506
文摘Acupuncture at Fengchi（GB20） in the posterior neck improves vertigo.However,subarachnoid hemorrhage and spinal epidural hematoma have been reported to occur after acupuncture in the posterior neck.Therefore,in the present study,we assessed the safety of acupuncture at Fengchi.Laboratory tests and adverse event reports were used to evaluate the safety of different acupuncture manipulations for the treatment of posterior circulation ischemia with vertigo.A total of 136 patients were randomly assigned to four groups.Verum acupuncture was conducted with different needle insertion directions（contralateral paropia or prominentia laryngea） and different needle twisting frequencies（60 or 120 times/minute） at Fengchi and matching acupoints（for example,Zhongwan [CV12],Qihai [CV6],Zusanli [ST36],and Fenglong [ST40]）.The patients received 14 treatments over 3–4 weeks.Routine blood analysis,hepatic and renal function tests,urine and feces tests and electrocardiography were performed before the first treatment session and after the final session.Adverse events were recorded after every session.Of the 136 patients,120 completed the study.There were no significant differences between pretreatment and posttreatment test results in any of the groups.Only five patients suffered from minor adverse events（needling pain,slight hematoma and transient chest tightness）.No serious adverse events were found.Our results indicate that a 14-session course of needling at Fengchi is relatively safe for treating posterior circulation ischemia with vertigo.
文摘Objective:To understand the clinical characteristics of patients with embryonic posterior cerebral artery and its correlation with abnormal vascular development.Methods:The clinical data of 396 patients with embryonic posterior cerebral artery confirmed by magnetic resonance angiography(MRA)and computed tomography angiography(CTA)were analyzed.Results:Two-hundred patients had clinical manifestations of posterior circulation ischemia,including recurrent dizziness,vertigo,and tinnitus;45 had headaches,97 had limb weakness,and 16 patients had syncope or impaired consciousness.Seventy-six patients with circulatory infarction were admitted to the hospital.There were 251 patients with history of hypertension,74 with diabetes,113 with hyperlipidemia,13 with dominant vertebral artery,10 with intracranial aneurysm,and 19 with absence of A1 segment of the anterior cerebral artery(considering developmental variation).Conclusion:Embryonic posterior cerebral artery develops abnormally during the embryonic period,often accompanied by abnormal vascular access.Due to abnormal hemodynamics,the incidence of posterior circulation ischemia,aneurysm,and infarction increases in such patients.
文摘目的探讨老年后循环缺血性卒中患者预后及危险因素。方法选取河北省承德市中心医院老年后循环缺血性卒中患者120例,根据治疗后3个月预后情况进行分组,分析预后不良和良好患者临床一般资料、外周血空腹血糖、糖化血红蛋白(hemoglobin A_(1)c,HbA_(1)c)等差异,总结老年后循环缺血性卒中患者预后的影响因素。结果预后不良患者39例,预后不良发生率为32.50%。预后不良组年龄和入院期间最高美国国立卫生研究所卒中量表(National Institute of Health Stroke Scale,NIHSS)评分分别为(68.93±4.02)岁和(19.30±2.50)分,高于预后良好组(P<0.05)。预后不良组空腹血糖、HbA_(1)c、脂蛋白相关磷脂酶a2(lipoprotein associated phospholipase A2,LP-PLA2)、超敏C反应蛋白(high-sensitivity C-reactive protein,hs-CRP)和血小板活化因子(platelet activating factor,PAF)分别为(7.28±0.92)mmol/L、(7.02±0.86)%、(330.50±65.53)μg/L、(20.22±6.43)ng/L和(248.23±44.18)ng/L,高于预后良好组(P<0.05)。Logistic回归分析,显示年龄、入院期间最高NIHSS评分、空腹血糖、LP-PLA2、PAF是患者预后的影响因素(P<0.05)。构建的方程预测预后不良的ROC曲线下面积为0.884(95%CI:0.821~0.948),P<0.05,敏感度和特异度分别为84.60%和81.50%。结论老年后循环缺血性卒中患者预后不良比例高,预后情况受患者年龄、入院期间最高NIHSS评分、空腹血糖、LP-PLA2、PAF的影响,同时由此构建的模型对患者预后不良具有较高的预测价值。
