目的探讨急性脑梗死患者治疗中急诊急救模式的应用效果。方法回顾性选取急性脑梗死患者100例,依据治疗方法分为急诊急救模式组和常规急诊治疗组,每组各50例。结果急诊急救模式组患者的急诊急救成功率高于常规急诊治疗组,从入院到急救医...目的探讨急性脑梗死患者治疗中急诊急救模式的应用效果。方法回顾性选取急性脑梗死患者100例,依据治疗方法分为急诊急救模式组和常规急诊治疗组,每组各50例。结果急诊急救模式组患者的急诊急救成功率高于常规急诊治疗组,从入院到急救医师接诊,时间短于常规急诊治疗组;从入院到开具CT报告,时间短于常规急诊治疗组;从入院到静脉溶栓,时间短于常规急诊治疗组;从入院到动脉成功置鞘,时间短于常规急诊治疗组;从置鞘到血管再通,时间短于常规急诊治疗组。美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)评分、改良爱丁堡-斯堪的纳维亚评分(Improved Edinburgh Scandinavian Score,CSS)评分均低于常规急诊治疗组,简易精神状态检查量表(Mini Mental Status Examination,MMSE)评分、改良Barthel指数量表(Modified Barthel Index,MBI)评分均高于常规急诊治疗组,差异均具有统计学意义(P<0.05)。急诊急救模式组患者的力气、手功能、交流、记忆与思维、参与、情绪、移动能力、日常生活能力评分均高于常规急诊治疗组(P<0.05),并发症发生率低于常规急诊治疗组(P<0.05)。结论急性脑梗死患者在救护中,急诊急救模式的应用效果优于常规急诊救护。展开更多
Background: Atrial fibrillation commonly occurs following cardiac surgery, particularly after coronary artery bypass grafting. Magnesium, known for its stabilizing effect on cell membranes, has shown promise in preven...Background: Atrial fibrillation commonly occurs following cardiac surgery, particularly after coronary artery bypass grafting. Magnesium, known for its stabilizing effect on cell membranes, has shown promise in preventing postoperative atrial fibrillation. This study aimed to assess the impact of intravenous magnesium infusion in preventing atrial fibrillation after off-pump coronary artery bypass grafting, where maintaining stable cell membranes is crucial in averting this complication. Methods: A cross-sectional study was conducted at the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, from March 2020 to February 2022. Sixty-six patients who underwent off-pump coronary artery bypass grafting were enrolled and divided into two groups. Group A (n = 33) received intravenous magnesium sulfate (10 mmol/2.47gm) for three days after surgery, while Group B (n = 33) did not receive magnesium sulfate. Postoperative atrial fibrillation occurrence in the Intensive Care Unit (ICU) within three days after surgery was evaluated using convenient sampling. Statistical analysis was performed with SPSS version 26.0, utilizing independent Student’s t-test for continuous data and Chi-square and Fisher’s exact test for categorical data. A p-value of ≤0.05 was considered statistically significant. Results: No significant differences in age or gender were observed between the two groups. Group B exhibited significantly lower magnesium levels than Group A on the 0<sup>th</sup>, 1<sup>st</sup>, 2<sup>nd</sup>, and 3<sup>rd</sup> days post-surgery. Additionally, Group B experienced a higher incidence of postoperative atrial fibrillation, longer ICU stays, and two mortalities. The study did not detect any adverse effects associated with magnesium infusion. Conclusion: It has been demonstrated that administering magnesium intravenously after off-pump coronary artery bypass grafting can lower the chances of developing atrial fibrillation. This demonstrates the potential advantages of using magnesium as a preventative measure for postoperative atrial fibrillation in such cases.展开更多
目的对经桡动脉和股动脉途径行PCI患者的临床资料进行对比分析。方法选择行PCI的患者1011例,分为桡动脉组(355例)和股动脉组(656例),分析比较2组的手术成功率和手术并发症。结果桡动脉组和股动脉组患者手术成功率差异无统计学意义(97.7%...目的对经桡动脉和股动脉途径行PCI患者的临床资料进行对比分析。方法选择行PCI的患者1011例,分为桡动脉组(355例)和股动脉组(656例),分析比较2组的手术成功率和手术并发症。结果桡动脉组和股动脉组患者手术成功率差异无统计学意义(97.7% vs 99.2%,P>0.05)。2组患者1、2和3支病变行PCI时,手术和透视时间比较,差异无统计学意义(P>0.05)。与股动脉组比较,桡动脉组患者复杂病变和慢性闭塞病变行PCI时,手术和透视时间明显延长,穿刺局部血肿明显降低(P<0.05)。结论经桡动脉途径和股动脉途径行PCI疗效相似,但经桡动脉途径并发症少,复杂病变和慢性闭塞病变行PCI时选择经股动脉途径优于桡动脉途径。展开更多
目的评价胃癌D2根治术后同期放化疗与化疗的疗效及毒副反应。方法计算机检索2013年10月之前纳入Cochrane library图书馆、Embase数据库、Pub Med数据库、Web of Science数据库、Wanfang数据库、CNKI数据库中比较胃癌D2根治术后同期放化...目的评价胃癌D2根治术后同期放化疗与化疗的疗效及毒副反应。方法计算机检索2013年10月之前纳入Cochrane library图书馆、Embase数据库、Pub Med数据库、Web of Science数据库、Wanfang数据库、CNKI数据库中比较胃癌D2根治术后同期放化疗与化疗的随机对照（RCT）研究。依据数据同质性或异质性确定数据使用固定效应模型或随机效应模型。使用Rev Man 5.2软件进行数据分析,两组之间的差异用OR值和95%CI描述。结果共纳入5个RCT研究,总计979例患者。通过Meta分析得出：胃癌D2根治术后同期放化疗与化疗相比,放化疗显著提高了5年局部无复发生存率（LRRFS）及3年总生存率（OS）,但不能提高5年无远处复发生存率（DMRFS）及1年、3年、5年无病生存率（DFS）和1年、5年OS;且拥有和化疗同样的1~2级、3~4级恶心呕吐不良反应及1~2级、3~4级白细胞毒性反应。结论今后研究应依据胃癌的分期、种族、淋巴结转移及淋巴结清扫数目来确定胃癌D2根治术术后同期放化疗与化疗。展开更多
文摘目的探讨急性脑梗死患者治疗中急诊急救模式的应用效果。方法回顾性选取急性脑梗死患者100例,依据治疗方法分为急诊急救模式组和常规急诊治疗组,每组各50例。结果急诊急救模式组患者的急诊急救成功率高于常规急诊治疗组,从入院到急救医师接诊,时间短于常规急诊治疗组;从入院到开具CT报告,时间短于常规急诊治疗组;从入院到静脉溶栓,时间短于常规急诊治疗组;从入院到动脉成功置鞘,时间短于常规急诊治疗组;从置鞘到血管再通,时间短于常规急诊治疗组。美国国立卫生研究院卒中量表(National Institute of Health Stroke Scale,NIHSS)评分、改良爱丁堡-斯堪的纳维亚评分(Improved Edinburgh Scandinavian Score,CSS)评分均低于常规急诊治疗组,简易精神状态检查量表(Mini Mental Status Examination,MMSE)评分、改良Barthel指数量表(Modified Barthel Index,MBI)评分均高于常规急诊治疗组,差异均具有统计学意义(P<0.05)。急诊急救模式组患者的力气、手功能、交流、记忆与思维、参与、情绪、移动能力、日常生活能力评分均高于常规急诊治疗组(P<0.05),并发症发生率低于常规急诊治疗组(P<0.05)。结论急性脑梗死患者在救护中,急诊急救模式的应用效果优于常规急诊救护。
文摘Background: Atrial fibrillation commonly occurs following cardiac surgery, particularly after coronary artery bypass grafting. Magnesium, known for its stabilizing effect on cell membranes, has shown promise in preventing postoperative atrial fibrillation. This study aimed to assess the impact of intravenous magnesium infusion in preventing atrial fibrillation after off-pump coronary artery bypass grafting, where maintaining stable cell membranes is crucial in averting this complication. Methods: A cross-sectional study was conducted at the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, from March 2020 to February 2022. Sixty-six patients who underwent off-pump coronary artery bypass grafting were enrolled and divided into two groups. Group A (n = 33) received intravenous magnesium sulfate (10 mmol/2.47gm) for three days after surgery, while Group B (n = 33) did not receive magnesium sulfate. Postoperative atrial fibrillation occurrence in the Intensive Care Unit (ICU) within three days after surgery was evaluated using convenient sampling. Statistical analysis was performed with SPSS version 26.0, utilizing independent Student’s t-test for continuous data and Chi-square and Fisher’s exact test for categorical data. A p-value of ≤0.05 was considered statistically significant. Results: No significant differences in age or gender were observed between the two groups. Group B exhibited significantly lower magnesium levels than Group A on the 0<sup>th</sup>, 1<sup>st</sup>, 2<sup>nd</sup>, and 3<sup>rd</sup> days post-surgery. Additionally, Group B experienced a higher incidence of postoperative atrial fibrillation, longer ICU stays, and two mortalities. The study did not detect any adverse effects associated with magnesium infusion. Conclusion: It has been demonstrated that administering magnesium intravenously after off-pump coronary artery bypass grafting can lower the chances of developing atrial fibrillation. This demonstrates the potential advantages of using magnesium as a preventative measure for postoperative atrial fibrillation in such cases.
文摘目的对经桡动脉和股动脉途径行PCI患者的临床资料进行对比分析。方法选择行PCI的患者1011例,分为桡动脉组(355例)和股动脉组(656例),分析比较2组的手术成功率和手术并发症。结果桡动脉组和股动脉组患者手术成功率差异无统计学意义(97.7% vs 99.2%,P>0.05)。2组患者1、2和3支病变行PCI时,手术和透视时间比较,差异无统计学意义(P>0.05)。与股动脉组比较,桡动脉组患者复杂病变和慢性闭塞病变行PCI时,手术和透视时间明显延长,穿刺局部血肿明显降低(P<0.05)。结论经桡动脉途径和股动脉途径行PCI疗效相似,但经桡动脉途径并发症少,复杂病变和慢性闭塞病变行PCI时选择经股动脉途径优于桡动脉途径。
文摘目的评价胃癌D2根治术后同期放化疗与化疗的疗效及毒副反应。方法计算机检索2013年10月之前纳入Cochrane library图书馆、Embase数据库、Pub Med数据库、Web of Science数据库、Wanfang数据库、CNKI数据库中比较胃癌D2根治术后同期放化疗与化疗的随机对照（RCT）研究。依据数据同质性或异质性确定数据使用固定效应模型或随机效应模型。使用Rev Man 5.2软件进行数据分析,两组之间的差异用OR值和95%CI描述。结果共纳入5个RCT研究,总计979例患者。通过Meta分析得出：胃癌D2根治术后同期放化疗与化疗相比,放化疗显著提高了5年局部无复发生存率（LRRFS）及3年总生存率（OS）,但不能提高5年无远处复发生存率（DMRFS）及1年、3年、5年无病生存率（DFS）和1年、5年OS;且拥有和化疗同样的1~2级、3~4级恶心呕吐不良反应及1~2级、3~4级白细胞毒性反应。结论今后研究应依据胃癌的分期、种族、淋巴结转移及淋巴结清扫数目来确定胃癌D2根治术术后同期放化疗与化疗。
