The development of the construction industry is shifting towards low-carbon construction,so it is necessary to improve and optimize related construction concepts,methods,and processes.By improving resource and energy ...The development of the construction industry is shifting towards low-carbon construction,so it is necessary to improve and optimize related construction concepts,methods,and processes.By improving resource and energy control efficiency in building projects,minimizing construction waste,and reducing environmental impact,a foundation for the sustainable development of the industry can be established.This paper mainly analyzes the significance of low-carbon energy-saving construction technology and the control factors of construction,summarizes the status quo of the development of building energy-saving construction,and puts forward strategies for applying building energy-saving construction technology.These strategies serve to achieve low-carbon and energy-saving goals to promote the healthy development of energy-saving construction.展开更多
Green energy conservation is the mainstream trend in the current development of the construction industry.The application of energy-saving technology in building electrical system design can effectively reduce energy ...Green energy conservation is the mainstream trend in the current development of the construction industry.The application of energy-saving technology in building electrical system design can effectively reduce energy consumption,avoid unnecessary energy consumption,and truly achieve energy conservation and environmental protection.Based on this,the article elaborates on the principles of energy-saving design in building electrical systems,and actively explores the application of energy-saving technologies from different perspectives such as optimizing power supply and distribution system design,adopting high-efficiency energy-saving lighting equipment,applying renewable energy,promoting smart home technology,and improving the efficiency of building electrical equipment.展开更多
This article aims to explore the mutual benefits and potential of agricultural trade between China and Mongolia,analyzing the current situation of agricultural resources,trade history,and policy environment of the two...This article aims to explore the mutual benefits and potential of agricultural trade between China and Mongolia,analyzing the current situation of agricultural resources,trade history,and policy environment of the two countries.The study finds that China-Mongolia agricultural trade shows significant economic complementarity.Trade activities not only promote economic growth in both countries but also deepen social and cultural exchanges.However,technical standards,political risks,and logistics costs remain major challenges facing trade cooperation.By strengthening policy coordination,investing in agricultural technology and infrastructure,and expanding the variety and markets of trade,the potential for cooperation in China-Mongolia agricultural trade can be further enhanced.These measures will help improve the efficiency and benefits of bilateral trade,achieving a win-win development.展开更多
In this study,we investigated on the application of planar lightwave circuit(PLC)technology in energy-saving control of tunnel lighting.The application status of PLC in the field of energy saving followed by the neces...In this study,we investigated on the application of planar lightwave circuit(PLC)technology in energy-saving control of tunnel lighting.The application status of PLC in the field of energy saving followed by the necessity of energy saving in tunnel lighting was analyzed.Finally,the application of PLC in tunnel lighting energy-saving control around the three dimensions of system overall architecture design,control scheme,and program control process was investigated.The results showed that the system meets the requirements of control effect,robustness,and visual effect after trial operation,and is suitable for practical applications.展开更多
Crack monitoring plays a great role in modern structural health monitoring, however, most of the conventional crack inspections have disadvantages in terms of the accuracy, expense, reliability, durability and level o...Crack monitoring plays a great role in modern structural health monitoring, however, most of the conventional crack inspections have disadvantages in terms of the accuracy, expense, reliability, durability and level of instrumentation required. Thus, development of a simple and reliable crack inspection technique that allows continuous monitoring has been desired. In this paper, electrical potential technique and modern surface technology are employed together to develop a new structural surface crack monitoring method. A special crack monitoring coating sensor based on electrical potential technique was deposited on the hot spot of the structure by modern surface technology. The sensor consists of three layers: the isolated layer, the sensing layer and the protective layer. The isolated layer is prepared by anodic oxidation technology, the sensing layer is made of ion plated copper, and the protective layer is made of silicone. The thickness of each layer is at micrometer magnitude. The electrical conductivity of the sensor is very stable, and the fatigue performance of the specimen with or without coating sensor is nearly unchanged. The crack monitoring experiment result shows that there are two sudden rises of the coating sensor electrical potential values, corresponding to different stages of the crack initiation and propagation. Since the width of the surface coating sensor is only 0.5 mm, this crack monitoring sensor can detect the propagation of cracks less than 0.5 mm long. The method proposed takes the simplicity of electrical potential technique and can monitor surface crack of nearly all kinds of structures precisely. The results of this paper may form the basis of a new crack monitoring system.展开更多
In order to effectively detect potential geology anomalous bodies in coal bearing formation,such as coal seam thickness variation,small faults,goafs and collapse columns,and provide scientific guidance for safe and ef...In order to effectively detect potential geology anomalous bodies in coal bearing formation,such as coal seam thickness variation,small faults,goafs and collapse columns,and provide scientific guidance for safe and efficient mining,the SUMMIT-II EX explosion-proof seismic slot wave instrument,produced by German DMT Company,was used to detect the underground channel wave with the help of transmission method,reflection method and transflective method.Region area detection experiment in mining face had been carried out thanks to the advantage of channel wave,such as its great dispersion,abundant geology information,strong anti-interference ability and long-distance detecting.The experimental results showed that:(1)Coal seam thickness variation in extremely unstable coal seam has been quantitatively interpreted with an accuracy of more than 80%generally;(2)The faults,goafs and collapse columns could be detected and predicted accurately;(3)Experimental detection of gas enrichment areas,stress concentration regions and water inrush risk zone has been collated;(4)A research system of disaster-causing geology anomalous body detection by in-seam seismic survey has been built,valuable and innovative achievements have been got.Series of innovation obtained for the first time in this study indicated that it was more effective to detect disaster-causing potential geology anomalies by in-seam seismic survey than by ground seismic survey.It had significant scientific value and application prospect under complex coal seam conditions.展开更多
Objective:To search the the differentially expressed genes between breast cell carcinoma tissues and normal tissues by using bioinformatics technology,and the potential therapeutic drugs for breast cancer were identif...Objective:To search the the differentially expressed genes between breast cell carcinoma tissues and normal tissues by using bioinformatics technology,and the potential therapeutic drugs for breast cancer were identified,which can provide reference for clinical immune targeted therapy and drug therapy of breast cancer in the future.Methods:"Breast cancer"was searched by using Gene Expression Omnibus(GEO),and GSE79586 chip data was downloaded.The differentially expressed genes in the control group and the breast cancer model group were screened by using bio-communication technology and subjected to GO function analysis,KEGG pathway analysis,differential gene characteristic expression analysis and protein-protein interaction network(PPI)analysis,and the analysis results were further visualized.Prognosis analysis,related function prediction and immune infiltration analysis were performed using the GEPIA,GeneMANIA,and Timer2.0 databases,respectively.Finally,the compounds with potential therapeutic effects on breast cancer are identified through Connectivity Map(CMap).Western blotting and real-time PCR(RT-PCR)were used to verify the core genes and potential therapeutic agents with the highest correlation in vitro.Results:A total of 3916 differentially expressed genes including 1786 up-regulated genes and 2130 down-regulated genes were screened.GO analysis showed that the differential genes were mainly involved in the positive regulation of phosphorylation,secretory vesicles,racemase and epimerase activities.KEGG analysis showed that differential genes were involved in systemic lupus erythematosus,alcoholism,sticky spots,amoebic dysentery Ras signal pathways and other disease pathways.The characteristic expression analysis of differential genes showed that MEK inhibitors,HSP90 inhibitors and signal transduction pathway kinase inhibitors were drugs similar to the differential genes.PPI results showed that H2AFJ,TFF1,GATA3,FOXA1,and CDH1 were core genes related to breast cancer.Two core genes of H2AFJ and TFF1 with the highest correlation were further selected for GEPIA analysis.The results of the analysis showed that the mRNA expression levels of H2AFJ and TFF1 in breast cancer cells were significantly higher than those in normal tissues,and there was a significant correlation with the pathological staging,overall survival rate and disease-free survival rate of breast cancer patients.H2AFJ and TFF1 may be potential prognostic biomarkers for survival of breast cancer patients.The functions of differentially expressed H2AFJ and TFF1 are mainly related to hormone receptor binding,epithelial structure maintenance and epigenetic negative regulation of genes,chromatin tissue involved in negative regulation of transcription,etc.The results of immune infiltration showed that the expressions of H2AFJ and TFF1 had a significant correlation with the infiltration of macrophages,neutrophils,monocytes,CD4+T,CD8+T,B lymphocytes and other immune cells.CMap results showed that compounds such as Gefitinib,Alpelisib,Sorafenib,and Sunitinib had potential therapeutic effects on breast cancer.Western blot and RT-PCR results showed that H2AFJ and TFF1 were significantly overexpressed in breast cancer cells.Gefitinib significantly inhibited the expression of H2AFJ and TFF1 in breast cancer cells(P<0.05,P<0.01).Conclusion:In this study,differentially expressed genes between breast cell carcinoma tissues and normal tissues were screened out by bioinformatics means to further identify key genes and compounds with potential therapeutic effects in the onset process of breast cancer and to further verify the effectiveness of the screened drugs on breast cancer through experiments.It will provide reference for clinical research and development of new drugs against breast cancer in the future in order to develop more effective treatment options.展开更多
Proteomics is a new technology that has been widely applied in the field of life and health science.It effectively addresses issues related to the impact of dietary structure on organs,tissues,and cells,as well as the...Proteomics is a new technology that has been widely applied in the field of life and health science.It effectively addresses issues related to the impact of dietary structure on organs,tissues,and cells,as well as the changes in proteins in various organs,tissues,and cells under disease conditions.The differential proteins identified through proteomics can serve as disease biomarkers and target proteins affecting health and can be used for disease diagnosis and health regulation.In this paper,the application of proteomics in the field of infl ammation in recent years was summarized,especially in the therapeutic target and mechanism of action,which opens up a new way for more effective prevention,diagnosis,and treatment of inflammation,and provides medical protection for human life and health.展开更多
Potential applications of Nano-scale science and technology are discussed in mineralogy, ore deposits, cosmochemistry and environmental sciences. Adsorption of nanometersized gold was experimentally studied on a varie...Potential applications of Nano-scale science and technology are discussed in mineralogy, ore deposits, cosmochemistry and environmental sciences. Adsorption of nanometersized gold was experimentally studied on a variety of minerals and rocks.展开更多
This paper aims at solving the problems of low thermal collection rate,inconvenient maintenance,hindering indoor using during the application of passive solar technologies in rural houses in severe cold region.All the...This paper aims at solving the problems of low thermal collection rate,inconvenient maintenance,hindering indoor using during the application of passive solar technologies in rural houses in severe cold region.All these defects prevent the passive solar houses' further development. This paper chooses trombe wall,which has higher thermal efficiency of the passive solar house,as research object. The traditional vent is improved into a new type of ventilation device. This improvement overcomes the shortcoming,which traditional vent loses huge heat,and simplifies the construction of vent. Comparing with traditional trombe wall,the energy saving rate is 15. 69%.展开更多
HSDPA (High Speed Downlink Packet Access) technology is a type of enhanced WCDMA technology based on R5 and employed with a 5 MHz spectrum. It can provide a maximum bit rate of 13.9 Mb/s thereby dramatically extending...HSDPA (High Speed Downlink Packet Access) technology is a type of enhanced WCDMA technology based on R5 and employed with a 5 MHz spectrum. It can provide a maximum bit rate of 13.9 Mb/s thereby dramatically extending the transmission rate and spectrum efficiency of R99 version. Currently, it is the first choice of mobile operators for high bit rate mobile multimedia services. All the mobile technologies and their characteristics, which are employed by HSDPA system in WCDMA, are analyzed in the following. The possible applications of HSDPA are also discussed in this article.展开更多
Under the increasing demands as well as resource shortages in today’s society,energy-saving technologies in building water supply and drainage construction plays a vital role.Through the rational application of energ...Under the increasing demands as well as resource shortages in today’s society,energy-saving technologies in building water supply and drainage construction plays a vital role.Through the rational application of energy-saving technologies,energy consumption in water supply and drainage projects can be significantly minimized and wastage of water resources can be reduced.This will play a very promising role in promoting sustainable development of resources and environmental conservation in the modern era.This paper analyzes the application of energy-saving technology in building water supply and drainage construction,with an aspiration to make energy-saving technology more reasonable in today’s building water supply and drainage projects and to improve the quality of water supply and drainage construction projects,while achieving effective environmental protection.展开更多
This article take cold regions of nlral residential building envelope as the research object, suitability technical theory as the theoretical basis, we evaluation of rural residential energy envelope because China's ...This article take cold regions of nlral residential building envelope as the research object, suitability technical theory as the theoretical basis, we evaluation of rural residential energy envelope because China's rural areas is chmacterized by large regional differences and to find a solution for the envelope. It could be considered as the useful reference for retrofit design of similar projects.展开更多
Discussion and study of the relationship between technological advance and human rights development can be achieved through both their interaction and interplay. In other words, we need to research and expound on the ...Discussion and study of the relationship between technological advance and human rights development can be achieved through both their interaction and interplay. In other words, we need to research and expound on the influences of technological advances on human rights development, and vice versa. However, despite the complexity of current human rights developments, this article, given length constraints, will only generally focus on whether technological advances have a potential role in promoting human rights improvements.展开更多
Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "...Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "4453" effects, as fol ows: "Four increases" include to increase loosen soil quantity in cultivation layers, soil nutri-ents use, "water pool" in soils, and "oxygen pool" in soils. Four reductions are to reduce soil erosion, carbon emission, salt content and heavy metal in soils. Five resistances refer to improve crop resistance capacity in terms of drought, high tem-perature, lower temperature, disease and lodging. Three improvements indicate to enhance photosynthetic efficiency over 10%, yield in 10%-30% and quality over 5%. lt is researched that without additional chemical fertilizer, yield could increase by 10% by labor force, animal, tractor or smash-ridging machine. What’s more, by smash-ridging cultivation, the depth can be 20 times or higher compared with tractor cultivation, with looser soils. lt is estimated that if smash-ridging cultivation is applied once in agricultural lands in China, present soil layers can be twice as deep as present. Specifical y, the thickness of loose soil-layers could be extended from 10-18 cm at present to 25-35 cm, and natural rainfal would increase by 40 bil ion cm3. After vitalization of soil nutrients, chemical fertilizer would decrease by 7 bil ion kg, and the increased c rops would feed more than 300 mil ion population as per yield at 7 50 kg/hm2.展开更多
The overall goal of this study is to characterize and to evaluate the potential uses of clay mined in the Nzaou locality. The Mou sample is argillaceous texture and medium plasticity (Ip = 28.9). Kaolinite is dominant...The overall goal of this study is to characterize and to evaluate the potential uses of clay mined in the Nzaou locality. The Mou sample is argillaceous texture and medium plasticity (Ip = 28.9). Kaolinite is dominant clay species (44.41%). It is associated with illite (9%). Quartz and rutile are the main non clay minerals. The CEC is 8.66 cmol+/kg. Organic matter is low (0.839%). Total shrinkage obtained by dilatometry at 1200°C is 9.26%. The chemical and mineralogical compositions have allowed using the ternary diagrams of Fabbri and Fiori that the MOU clay is favorable for glazed white stoneware (GWS) and for the production of clinker (KLK). Dondi typologies of ceramic tiles according to body color (mostly depending on the iron oxide content) and compactness (expressed by water absorption) have confirmed the use for the manufacture of the GWS and clinker. Classification always according to Dondi taking into account the rate of kaolinite, the fine fraction (°C will be vitrified. Flexural strength at 1200°C (16 MPa) does not correspond to the requirements of GWS or a clinker.展开更多
Continental shale oil is a general term for liquid hydrocarbons and many kinds of organic matter in continental organic-rich shale series with vitrinite reflectance of more than 0.5%at buried depth of more than 300 m,...Continental shale oil is a general term for liquid hydrocarbons and many kinds of organic matter in continental organic-rich shale series with vitrinite reflectance of more than 0.5%at buried depth of more than 300 m,and is an important type of source-rock oil and gas.Based on the evolution model of oil generation and expulsion in organic-rich shale series controlled by maturity,continental shale oil is divided into two types:medium-high maturity and medium-low maturity.(1)The continental shale series in China develop high-quality source rocks of freshwater and saltwater lacustrine facies,as well as multiple types of reservoirs,including clastic rocks,carbonate rocks,diamictite,tuff and shale,forming a number of"sweet sections"and"sweet areas"of continuous distribution inside or near source rocks,which have large scale resources.(2)Experimental analysis of organic rich shale samples shows that the shale samples with wavy and horizontal beddings have good storage conditions,and the horizontal permeability of shale is tens to hundreds of times of its vertical permeability,which is conducive to the lateral migration and accumulation of shale oil in the source rocks.(3)After evaluation,the geological resources of medium-high maturity shale oil are about 10 billion tons,which can be effectively developed by horizontal drilling and volumetric fracturing,and will be a practical field of oil exploration in recent years.Shale oil with medium and low maturity has huge resource potential,and technological recoverable resources of(70?90)billion tons,making it a strategic alternative resource of oil industry.However,economic development of this type of shale oil needs in-situ conversion technology breakthroughs.Continental shale oil is an inevitable choice in the process of Chinese continental petroleum exploration from"outside source"to"inside source".Making breakthroughs in the core technologies such as"sweet area"evaluation and optimization,horizontal well volume fracturing and in-situ conversion technology and equipment is the key to realizing scale development of continental shale oil economically.展开更多
The increasing penetration of renewables in power systems urgently entails the utilization of energy storage technologies.As the development of energy storage technologies depends highly on the profitability in electr...The increasing penetration of renewables in power systems urgently entails the utilization of energy storage technologies.As the development of energy storage technologies depends highly on the profitability in electricity markets,to evaluate the economic potentials for various types of energy storage technologies under the compre-hensive market environment is of great significance.To this end,this study aims at conducting a quantitative analysis on the economic potentials for typical energy storage technologies by establishing a joint clearing model for electric energy and ancillary service(AS)markets considering the operating features of energy storage systems(ESSs).Furthermore,a test system is adopted for numerical analysis that accurately represents for the real-world operation characteristics of power systems in China,with which the market prices,and operation schedules and profitability of ESSs are comparatively studied.The proposed methodology and results could provide benefi-cial references for the modifications on electricity markets and the development of ESSs towards the increasing penetration of renewables in power systems.展开更多
The common problem of cold strip continuous annealing furnaces is high exhaust gas temperature and great energy consumption. Taking the cold-strip continuous annealing furnaces of Baosteel No. 4 cold mill plant as an ...The common problem of cold strip continuous annealing furnaces is high exhaust gas temperature and great energy consumption. Taking the cold-strip continuous annealing furnaces of Baosteel No. 4 cold mill plant as an example, several waste heat recovery systems in the annealing furnaces are compared and their advantages and disadvantages are analyzed through different energy-saving technologies.展开更多
This paper discussed exploring"41635"potential of food for more than 400 million people through developing"Fenlong Agriculture"in China.It clarified that"5.0 Fenlong Technology"is compose...This paper discussed exploring"41635"potential of food for more than 400 million people through developing"Fenlong Agriculture"in China.It clarified that"5.0 Fenlong Technology"is composed of"drill type Fenlong tillage tools+Fenlong farming technology+Fenlong crop cultivation technology standards",and has coupling and interaction"common key technologies in agricultural production,resource utilization and ecological improvement,and"Great Science"connotation and characteristics,the yield increase rate for 40 kinds of crops in 26 provinces in China reached 10%-150%.China uses"5.0"Fenlong Technology"to develop"Fenlong agriculture"to implement the optimization and transformation of 67 million ha of cultivated land,13 million ha of saline-alkali land,and 67 million ha of degraded grassland and related farming systems,excavating its new round of multiple activations and increasing the huge concentration of"gifted resources"such as soil,water,gas,temperature and light,develop"five systems","big pattern","rainfed and environment-friendly"and other types of Fenlong agriculture,so as to increase food,meat,fish and other food sources to feed 400 million people every year,increase natural soil storage by 100 billion m3,reduce groundwater collection by 60 billion m3,reduce the use of chemical fertilizers and pesticides by more than 30%,the comprehensive benefits including yield increase,quality improvement,water saving,chemical fertilizer reduction,ecological protection,and disaster reduction can increase by more than 50%(these are 41635 potential),to realize the objective that a place can feed its people by its own resources.展开更多
基金Research on Zero Emission Campus Construction Based on Plant Community Optimization(Project number:KJQN202305605)。
文摘The development of the construction industry is shifting towards low-carbon construction,so it is necessary to improve and optimize related construction concepts,methods,and processes.By improving resource and energy control efficiency in building projects,minimizing construction waste,and reducing environmental impact,a foundation for the sustainable development of the industry can be established.This paper mainly analyzes the significance of low-carbon energy-saving construction technology and the control factors of construction,summarizes the status quo of the development of building energy-saving construction,and puts forward strategies for applying building energy-saving construction technology.These strategies serve to achieve low-carbon and energy-saving goals to promote the healthy development of energy-saving construction.
文摘Green energy conservation is the mainstream trend in the current development of the construction industry.The application of energy-saving technology in building electrical system design can effectively reduce energy consumption,avoid unnecessary energy consumption,and truly achieve energy conservation and environmental protection.Based on this,the article elaborates on the principles of energy-saving design in building electrical systems,and actively explores the application of energy-saving technologies from different perspectives such as optimizing power supply and distribution system design,adopting high-efficiency energy-saving lighting equipment,applying renewable energy,promoting smart home technology,and improving the efficiency of building electrical equipment.
文摘This article aims to explore the mutual benefits and potential of agricultural trade between China and Mongolia,analyzing the current situation of agricultural resources,trade history,and policy environment of the two countries.The study finds that China-Mongolia agricultural trade shows significant economic complementarity.Trade activities not only promote economic growth in both countries but also deepen social and cultural exchanges.However,technical standards,political risks,and logistics costs remain major challenges facing trade cooperation.By strengthening policy coordination,investing in agricultural technology and infrastructure,and expanding the variety and markets of trade,the potential for cooperation in China-Mongolia agricultural trade can be further enhanced.These measures will help improve the efficiency and benefits of bilateral trade,achieving a win-win development.
文摘In this study,we investigated on the application of planar lightwave circuit(PLC)technology in energy-saving control of tunnel lighting.The application status of PLC in the field of energy saving followed by the necessity of energy saving in tunnel lighting was analyzed.Finally,the application of PLC in tunnel lighting energy-saving control around the three dimensions of system overall architecture design,control scheme,and program control process was investigated.The results showed that the system meets the requirements of control effect,robustness,and visual effect after trial operation,and is suitable for practical applications.
基金supported by National Hi-tech Research and Development Program of China (863 Program, Grant No. 2009AA03Z103)Scientific Research Foundation for the Returned Overseas Chinese Scholars of Ministry of Education of China (Grant No. [2006]331)
文摘Crack monitoring plays a great role in modern structural health monitoring, however, most of the conventional crack inspections have disadvantages in terms of the accuracy, expense, reliability, durability and level of instrumentation required. Thus, development of a simple and reliable crack inspection technique that allows continuous monitoring has been desired. In this paper, electrical potential technique and modern surface technology are employed together to develop a new structural surface crack monitoring method. A special crack monitoring coating sensor based on electrical potential technique was deposited on the hot spot of the structure by modern surface technology. The sensor consists of three layers: the isolated layer, the sensing layer and the protective layer. The isolated layer is prepared by anodic oxidation technology, the sensing layer is made of ion plated copper, and the protective layer is made of silicone. The thickness of each layer is at micrometer magnitude. The electrical conductivity of the sensor is very stable, and the fatigue performance of the specimen with or without coating sensor is nearly unchanged. The crack monitoring experiment result shows that there are two sudden rises of the coating sensor electrical potential values, corresponding to different stages of the crack initiation and propagation. Since the width of the surface coating sensor is only 0.5 mm, this crack monitoring sensor can detect the propagation of cracks less than 0.5 mm long. The method proposed takes the simplicity of electrical potential technique and can monitor surface crack of nearly all kinds of structures precisely. The results of this paper may form the basis of a new crack monitoring system.
基金supported by the Key Project of the National Natural Science Foundation of China(Grant No.41130419).
文摘In order to effectively detect potential geology anomalous bodies in coal bearing formation,such as coal seam thickness variation,small faults,goafs and collapse columns,and provide scientific guidance for safe and efficient mining,the SUMMIT-II EX explosion-proof seismic slot wave instrument,produced by German DMT Company,was used to detect the underground channel wave with the help of transmission method,reflection method and transflective method.Region area detection experiment in mining face had been carried out thanks to the advantage of channel wave,such as its great dispersion,abundant geology information,strong anti-interference ability and long-distance detecting.The experimental results showed that:(1)Coal seam thickness variation in extremely unstable coal seam has been quantitatively interpreted with an accuracy of more than 80%generally;(2)The faults,goafs and collapse columns could be detected and predicted accurately;(3)Experimental detection of gas enrichment areas,stress concentration regions and water inrush risk zone has been collated;(4)A research system of disaster-causing geology anomalous body detection by in-seam seismic survey has been built,valuable and innovative achievements have been got.Series of innovation obtained for the first time in this study indicated that it was more effective to detect disaster-causing potential geology anomalies by in-seam seismic survey than by ground seismic survey.It had significant scientific value and application prospect under complex coal seam conditions.
基金supported by Supported by the National Natural Science Foundation of China(81603418,82074271)Scientific Research Project of"Outstanding Innovative Talents Support Plan"of Heilongjiang University of Chinese Medicine(2020YQ05)。
文摘Objective:To search the the differentially expressed genes between breast cell carcinoma tissues and normal tissues by using bioinformatics technology,and the potential therapeutic drugs for breast cancer were identified,which can provide reference for clinical immune targeted therapy and drug therapy of breast cancer in the future.Methods:"Breast cancer"was searched by using Gene Expression Omnibus(GEO),and GSE79586 chip data was downloaded.The differentially expressed genes in the control group and the breast cancer model group were screened by using bio-communication technology and subjected to GO function analysis,KEGG pathway analysis,differential gene characteristic expression analysis and protein-protein interaction network(PPI)analysis,and the analysis results were further visualized.Prognosis analysis,related function prediction and immune infiltration analysis were performed using the GEPIA,GeneMANIA,and Timer2.0 databases,respectively.Finally,the compounds with potential therapeutic effects on breast cancer are identified through Connectivity Map(CMap).Western blotting and real-time PCR(RT-PCR)were used to verify the core genes and potential therapeutic agents with the highest correlation in vitro.Results:A total of 3916 differentially expressed genes including 1786 up-regulated genes and 2130 down-regulated genes were screened.GO analysis showed that the differential genes were mainly involved in the positive regulation of phosphorylation,secretory vesicles,racemase and epimerase activities.KEGG analysis showed that differential genes were involved in systemic lupus erythematosus,alcoholism,sticky spots,amoebic dysentery Ras signal pathways and other disease pathways.The characteristic expression analysis of differential genes showed that MEK inhibitors,HSP90 inhibitors and signal transduction pathway kinase inhibitors were drugs similar to the differential genes.PPI results showed that H2AFJ,TFF1,GATA3,FOXA1,and CDH1 were core genes related to breast cancer.Two core genes of H2AFJ and TFF1 with the highest correlation were further selected for GEPIA analysis.The results of the analysis showed that the mRNA expression levels of H2AFJ and TFF1 in breast cancer cells were significantly higher than those in normal tissues,and there was a significant correlation with the pathological staging,overall survival rate and disease-free survival rate of breast cancer patients.H2AFJ and TFF1 may be potential prognostic biomarkers for survival of breast cancer patients.The functions of differentially expressed H2AFJ and TFF1 are mainly related to hormone receptor binding,epithelial structure maintenance and epigenetic negative regulation of genes,chromatin tissue involved in negative regulation of transcription,etc.The results of immune infiltration showed that the expressions of H2AFJ and TFF1 had a significant correlation with the infiltration of macrophages,neutrophils,monocytes,CD4+T,CD8+T,B lymphocytes and other immune cells.CMap results showed that compounds such as Gefitinib,Alpelisib,Sorafenib,and Sunitinib had potential therapeutic effects on breast cancer.Western blot and RT-PCR results showed that H2AFJ and TFF1 were significantly overexpressed in breast cancer cells.Gefitinib significantly inhibited the expression of H2AFJ and TFF1 in breast cancer cells(P<0.05,P<0.01).Conclusion:In this study,differentially expressed genes between breast cell carcinoma tissues and normal tissues were screened out by bioinformatics means to further identify key genes and compounds with potential therapeutic effects in the onset process of breast cancer and to further verify the effectiveness of the screened drugs on breast cancer through experiments.It will provide reference for clinical research and development of new drugs against breast cancer in the future in order to develop more effective treatment options.
基金funded by National Key R&D Program of China(2022YFF1100300).
文摘Proteomics is a new technology that has been widely applied in the field of life and health science.It effectively addresses issues related to the impact of dietary structure on organs,tissues,and cells,as well as the changes in proteins in various organs,tissues,and cells under disease conditions.The differential proteins identified through proteomics can serve as disease biomarkers and target proteins affecting health and can be used for disease diagnosis and health regulation.In this paper,the application of proteomics in the field of infl ammation in recent years was summarized,especially in the therapeutic target and mechanism of action,which opens up a new way for more effective prevention,diagnosis,and treatment of inflammation,and provides medical protection for human life and health.
文摘Potential applications of Nano-scale science and technology are discussed in mineralogy, ore deposits, cosmochemistry and environmental sciences. Adsorption of nanometersized gold was experimentally studied on a variety of minerals and rocks.
基金Sponsored by the National Science-Technology Support Plan Projects (Grant No.2011BAJ08B06-2)
文摘This paper aims at solving the problems of low thermal collection rate,inconvenient maintenance,hindering indoor using during the application of passive solar technologies in rural houses in severe cold region.All these defects prevent the passive solar houses' further development. This paper chooses trombe wall,which has higher thermal efficiency of the passive solar house,as research object. The traditional vent is improved into a new type of ventilation device. This improvement overcomes the shortcoming,which traditional vent loses huge heat,and simplifies the construction of vent. Comparing with traditional trombe wall,the energy saving rate is 15. 69%.
文摘HSDPA (High Speed Downlink Packet Access) technology is a type of enhanced WCDMA technology based on R5 and employed with a 5 MHz spectrum. It can provide a maximum bit rate of 13.9 Mb/s thereby dramatically extending the transmission rate and spectrum efficiency of R99 version. Currently, it is the first choice of mobile operators for high bit rate mobile multimedia services. All the mobile technologies and their characteristics, which are employed by HSDPA system in WCDMA, are analyzed in the following. The possible applications of HSDPA are also discussed in this article.
文摘Under the increasing demands as well as resource shortages in today’s society,energy-saving technologies in building water supply and drainage construction plays a vital role.Through the rational application of energy-saving technologies,energy consumption in water supply and drainage projects can be significantly minimized and wastage of water resources can be reduced.This will play a very promising role in promoting sustainable development of resources and environmental conservation in the modern era.This paper analyzes the application of energy-saving technology in building water supply and drainage construction,with an aspiration to make energy-saving technology more reasonable in today’s building water supply and drainage projects and to improve the quality of water supply and drainage construction projects,while achieving effective environmental protection.
文摘This article take cold regions of nlral residential building envelope as the research object, suitability technical theory as the theoretical basis, we evaluation of rural residential energy envelope because China's rural areas is chmacterized by large regional differences and to find a solution for the envelope. It could be considered as the useful reference for retrofit design of similar projects.
文摘Discussion and study of the relationship between technological advance and human rights development can be achieved through both their interaction and interplay. In other words, we need to research and expound on the influences of technological advances on human rights development, and vice versa. However, despite the complexity of current human rights developments, this article, given length constraints, will only generally focus on whether technological advances have a potential role in promoting human rights improvements.
基金Supported by the Key Project of Science and Technology of Guangxi(1222014-2C)Achievements Transformation Project of Guangxi Academy of Agricultural Science and Technology(201405)Fundamental Research Funds for Guangxi Academy of Agricultural Science and Technology(2014YZ07)~~
文摘Yuan Longping proposed that smash-ridging technology could be extend-ed widely nationwide. ln the research, smash-ridging technology reconstruct cultiva-tion layers with loose soils in agricultural fields, creating "4453" effects, as fol ows: "Four increases" include to increase loosen soil quantity in cultivation layers, soil nutri-ents use, "water pool" in soils, and "oxygen pool" in soils. Four reductions are to reduce soil erosion, carbon emission, salt content and heavy metal in soils. Five resistances refer to improve crop resistance capacity in terms of drought, high tem-perature, lower temperature, disease and lodging. Three improvements indicate to enhance photosynthetic efficiency over 10%, yield in 10%-30% and quality over 5%. lt is researched that without additional chemical fertilizer, yield could increase by 10% by labor force, animal, tractor or smash-ridging machine. What’s more, by smash-ridging cultivation, the depth can be 20 times or higher compared with tractor cultivation, with looser soils. lt is estimated that if smash-ridging cultivation is applied once in agricultural lands in China, present soil layers can be twice as deep as present. Specifical y, the thickness of loose soil-layers could be extended from 10-18 cm at present to 25-35 cm, and natural rainfal would increase by 40 bil ion cm3. After vitalization of soil nutrients, chemical fertilizer would decrease by 7 bil ion kg, and the increased c rops would feed more than 300 mil ion population as per yield at 7 50 kg/hm2.
文摘The overall goal of this study is to characterize and to evaluate the potential uses of clay mined in the Nzaou locality. The Mou sample is argillaceous texture and medium plasticity (Ip = 28.9). Kaolinite is dominant clay species (44.41%). It is associated with illite (9%). Quartz and rutile are the main non clay minerals. The CEC is 8.66 cmol+/kg. Organic matter is low (0.839%). Total shrinkage obtained by dilatometry at 1200°C is 9.26%. The chemical and mineralogical compositions have allowed using the ternary diagrams of Fabbri and Fiori that the MOU clay is favorable for glazed white stoneware (GWS) and for the production of clinker (KLK). Dondi typologies of ceramic tiles according to body color (mostly depending on the iron oxide content) and compactness (expressed by water absorption) have confirmed the use for the manufacture of the GWS and clinker. Classification always according to Dondi taking into account the rate of kaolinite, the fine fraction (°C will be vitrified. Flexural strength at 1200°C (16 MPa) does not correspond to the requirements of GWS or a clinker.
基金Supported by the China National Science and Technology Major Project(2016ZX05046)
文摘Continental shale oil is a general term for liquid hydrocarbons and many kinds of organic matter in continental organic-rich shale series with vitrinite reflectance of more than 0.5%at buried depth of more than 300 m,and is an important type of source-rock oil and gas.Based on the evolution model of oil generation and expulsion in organic-rich shale series controlled by maturity,continental shale oil is divided into two types:medium-high maturity and medium-low maturity.(1)The continental shale series in China develop high-quality source rocks of freshwater and saltwater lacustrine facies,as well as multiple types of reservoirs,including clastic rocks,carbonate rocks,diamictite,tuff and shale,forming a number of"sweet sections"and"sweet areas"of continuous distribution inside or near source rocks,which have large scale resources.(2)Experimental analysis of organic rich shale samples shows that the shale samples with wavy and horizontal beddings have good storage conditions,and the horizontal permeability of shale is tens to hundreds of times of its vertical permeability,which is conducive to the lateral migration and accumulation of shale oil in the source rocks.(3)After evaluation,the geological resources of medium-high maturity shale oil are about 10 billion tons,which can be effectively developed by horizontal drilling and volumetric fracturing,and will be a practical field of oil exploration in recent years.Shale oil with medium and low maturity has huge resource potential,and technological recoverable resources of(70?90)billion tons,making it a strategic alternative resource of oil industry.However,economic development of this type of shale oil needs in-situ conversion technology breakthroughs.Continental shale oil is an inevitable choice in the process of Chinese continental petroleum exploration from"outside source"to"inside source".Making breakthroughs in the core technologies such as"sweet area"evaluation and optimization,horizontal well volume fracturing and in-situ conversion technology and equipment is the key to realizing scale development of continental shale oil economically.
基金Qinchuangyuan Cited High-level Innovation and Entrepreneurship Talents Project under(Grant No:2021QCYRC4-36)National Natural Science Fundation of China(Grant No.:72173095).
文摘The increasing penetration of renewables in power systems urgently entails the utilization of energy storage technologies.As the development of energy storage technologies depends highly on the profitability in electricity markets,to evaluate the economic potentials for various types of energy storage technologies under the compre-hensive market environment is of great significance.To this end,this study aims at conducting a quantitative analysis on the economic potentials for typical energy storage technologies by establishing a joint clearing model for electric energy and ancillary service(AS)markets considering the operating features of energy storage systems(ESSs).Furthermore,a test system is adopted for numerical analysis that accurately represents for the real-world operation characteristics of power systems in China,with which the market prices,and operation schedules and profitability of ESSs are comparatively studied.The proposed methodology and results could provide benefi-cial references for the modifications on electricity markets and the development of ESSs towards the increasing penetration of renewables in power systems.
文摘The common problem of cold strip continuous annealing furnaces is high exhaust gas temperature and great energy consumption. Taking the cold-strip continuous annealing furnaces of Baosteel No. 4 cold mill plant as an example, several waste heat recovery systems in the annealing furnaces are compared and their advantages and disadvantages are analyzed through different energy-saving technologies.
基金Special Fund Project for Innovation Driven Development of Guangxi(Gui Ke AA17204037)Key Science and Technology Project of Guangxi(Gui Ke AA16380017)Team Project of Guangxi Academy of Agricultural Sciences(2015YT60).
文摘This paper discussed exploring"41635"potential of food for more than 400 million people through developing"Fenlong Agriculture"in China.It clarified that"5.0 Fenlong Technology"is composed of"drill type Fenlong tillage tools+Fenlong farming technology+Fenlong crop cultivation technology standards",and has coupling and interaction"common key technologies in agricultural production,resource utilization and ecological improvement,and"Great Science"connotation and characteristics,the yield increase rate for 40 kinds of crops in 26 provinces in China reached 10%-150%.China uses"5.0"Fenlong Technology"to develop"Fenlong agriculture"to implement the optimization and transformation of 67 million ha of cultivated land,13 million ha of saline-alkali land,and 67 million ha of degraded grassland and related farming systems,excavating its new round of multiple activations and increasing the huge concentration of"gifted resources"such as soil,water,gas,temperature and light,develop"five systems","big pattern","rainfed and environment-friendly"and other types of Fenlong agriculture,so as to increase food,meat,fish and other food sources to feed 400 million people every year,increase natural soil storage by 100 billion m3,reduce groundwater collection by 60 billion m3,reduce the use of chemical fertilizers and pesticides by more than 30%,the comprehensive benefits including yield increase,quality improvement,water saving,chemical fertilizer reduction,ecological protection,and disaster reduction can increase by more than 50%(these are 41635 potential),to realize the objective that a place can feed its people by its own resources.