Dear Editor, Cystic echinococcosis （CE）, caused by Echinococcus granulosus in larval stage, is considered as one of the most dangerous parasitic zoonosis in the world. The obligate 2-host parasitic cycle of Echinoc...Dear Editor, Cystic echinococcosis （CE）, caused by Echinococcus granulosus in larval stage, is considered as one of the most dangerous parasitic zoonosis in the world. The obligate 2-host parasitic cycle of Echinococcus granulosus is predominantly synanthropic. Dogs are the usual definitive hosts, and lots of mammalian species can be intermediate hosts, including domestic livestock and human[I2]. In the Tibetan plateau, China, the population is mainly Tibetans primarily engaged in livestock husbandry and CE is therefore a health problem for both people and animal in Tibetan communities. The reported infection rate of Echinococcus gronulosus in slaughtered yak in slaughterhouses is usually very high, being about 50% or higher as reported, and the liver and lungs are the main affected organs[34].展开更多
In 1945,Porter et al.published an electon microscopy study of cultured chick fibroblasts in which they observed：＇a granular background and details of a darker lacelike reticulum which in places appears to be made up...In 1945,Porter et al.published an electon microscopy study of cultured chick fibroblasts in which they observed：＇a granular background and details of a darker lacelike reticulum which in places appears to be made up of chains of＂vesicles＂＇（Porter et al.,1945）.This constituted the first published observation of the endoplasmic reticulum（ER）and,while it was not evident at that time,this cytoplasmic system of interconnecting membrane-lined channels, comprising vesicles, tubules and cisternae, has numerous important functions.展开更多
In a number of renal disease tubular epithelial cells often display hypertrophy rather than hyperplasia. This hypertrophy, characterized by an increase in protein conten and cell size, as well as an accumulation of ex...In a number of renal disease tubular epithelial cells often display hypertrophy rather than hyperplasia. This hypertrophy, characterized by an increase in protein conten and cell size, as well as an accumulation of extracellular matrix, is a key process which may lead subsequently to tubulointerstitial fibrosis and end-stage renal failure.展开更多
In the letter to the editor, Dr. Comings et al. proposed a potential explanation of our findings that the L allele rather than S allele of 5-HTTLPR was associated with higher anxiety levels and reduced amygdala-prefro...In the letter to the editor, Dr. Comings et al. proposed a potential explanation of our findings that the L allele rather than S allele of 5-HTTLPR was associated with higher anxiety levels and reduced amygdala-prefrontal cortex （PFC） connectivity in Han Chinese[1], which demonstrated an ＇allele reversal＇ in the genetics of the 5-HTTLPR gene in Asians versus Caucasians. The authors alleged that this ＇allele reversal＇ might simply result from maternal age and suggested that we test this on our datasets. Unfortunately,展开更多
基金supported by the National S&T Major Program,2008ZX10004-011the National Science and Technology Support Program,2006BA106B06WHO project,WP/09/MVP/ 001726
文摘Dear Editor, Cystic echinococcosis （CE）, caused by Echinococcus granulosus in larval stage, is considered as one of the most dangerous parasitic zoonosis in the world. The obligate 2-host parasitic cycle of Echinococcus granulosus is predominantly synanthropic. Dogs are the usual definitive hosts, and lots of mammalian species can be intermediate hosts, including domestic livestock and human[I2]. In the Tibetan plateau, China, the population is mainly Tibetans primarily engaged in livestock husbandry and CE is therefore a health problem for both people and animal in Tibetan communities. The reported infection rate of Echinococcus gronulosus in slaughtered yak in slaughterhouses is usually very high, being about 50% or higher as reported, and the liver and lungs are the main affected organs[34].
文摘In 1945,Porter et al.published an electon microscopy study of cultured chick fibroblasts in which they observed：＇a granular background and details of a darker lacelike reticulum which in places appears to be made up of chains of＂vesicles＂＇（Porter et al.,1945）.This constituted the first published observation of the endoplasmic reticulum（ER）and,while it was not evident at that time,this cytoplasmic system of interconnecting membrane-lined channels, comprising vesicles, tubules and cisternae, has numerous important functions.
文摘In a number of renal disease tubular epithelial cells often display hypertrophy rather than hyperplasia. This hypertrophy, characterized by an increase in protein conten and cell size, as well as an accumulation of extracellular matrix, is a key process which may lead subsequently to tubulointerstitial fibrosis and end-stage renal failure.
文摘In the letter to the editor, Dr. Comings et al. proposed a potential explanation of our findings that the L allele rather than S allele of 5-HTTLPR was associated with higher anxiety levels and reduced amygdala-prefrontal cortex （PFC） connectivity in Han Chinese[1], which demonstrated an ＇allele reversal＇ in the genetics of the 5-HTTLPR gene in Asians versus Caucasians. The authors alleged that this ＇allele reversal＇ might simply result from maternal age and suggested that we test this on our datasets. Unfortunately,
