Deep-Litter System is a high yield approach to raise swine with pollution free in a lower cost. In the research, based on the heat stress in summer caused by fermentation, three temperature-control systems were design...Deep-Litter System is a high yield approach to raise swine with pollution free in a lower cost. In the research, based on the heat stress in summer caused by fermentation, three temperature-control systems were designed, including natural ventilation through transoms, forced ventilation via fans, and cooling by hyperbaric spray system. Specifically, the latter intermittent auto-pressurized spray system developed in our lab, which could spray successively via pressure from storage tubes without wetting the fermentation bed, is suitable for the promotion with the deep-litter technology in rural regions , since the power consumption is only 1 kwh per day.展开更多
Objective To identify the status of knowledge,attitude,and behaviour toward evidence-based practice(EBP)among Chinese psychiatric nurses,and to examine the influencing factors of EBP behaviour.Methods We utilised a cr...Objective To identify the status of knowledge,attitude,and behaviour toward evidence-based practice(EBP)among Chinese psychiatric nurses,and to examine the influencing factors of EBP behaviour.Methods We utilised a cross-sectional design.A total of 923 psychiatric nurses from 168 hospitals in 27 provinces in the mainland of China participated in our survey.The EBP questionnaire,the barriers to research utilisation scale and the facilitators to research utilisation scale were used for data collection via WeChat group from July 2018 to April 2019.Multiple regression analysis was used to analyse the influencing factors of psychiatric nurses’evidence-based practice behaviour.Results The score of Chinese psychiatric nurses’EBP attitude,behaviour and knowledge were 4.81±1.34,4.11±1.36 and 3.53±1.29,respectively.Multiple regression analysis showed that nurses’EBP behaviour was mainly determined by knowledge and attitude,which together explained 61.8%of the variance.The two top barriers were the dimensions of presentation and research.Facilitators include managerial support,employing nurses with research skills as models and providing advanced education on evidence-based nursing.Conclusion Psychiatric nurses have positive attitudes toward EBP,but their level of knowledge and behaviour is insufficient.Heavy workload,insufficient time,and a lack of knowledge and skills is the main barrier.Managerial support,employing nurses with research skills as models and providing advanced education are the main facilitators.展开更多
BACKGROUND Patients with inflammatory bowel diseases(IBDs)generally have poor knowledge,attitude,and practice of their disease,while the data from China are lacking.AIM To address this knowledge disparity among Chines...BACKGROUND Patients with inflammatory bowel diseases(IBDs)generally have poor knowledge,attitude,and practice of their disease,while the data from China are lacking.AIM To address this knowledge disparity among Chinese patients with IBD.METHODS This web-based,cross-sectional study was conducted on a cohort of IBD patients who visited the Second Affiliated Hospital of Wenzhou Medical University between December 2022 and February 2023.Their socio-demographic information and the knowledge,attitude,and practice scores were collected and estimated using a self-designed questionnaire.Pearson’s correlation analysis was used to determine the pairwise correlations among knowledge,attitude,and practice scores.A multivariate logistic regression analysis was further performed to determine the independent factors associated with their knowledge,attitude,and practice scores.RESULTS A total of 353 patients(224 males)with IBD completed the questionnaires.The mean knowledge,attitude,and practice scores were 10.05±3.46(possible range:0-14),41.58±5.23(possible range:0-56),44.20±7.39(possible range:0-56),respectively,indicating good knowledge,positive attitude,and proactive practice toward IBD.Pearson’s correlation analysis showed that the knowledge score had significant positive correlations with the attitude score(r=0.371,P<0.001)and practice score(r=0.100,P<0.001).The attitude score had a significant positive correlation with the practice score(r=0.452,P<0.001).Moreover,multivariate logistic regression analysis showed that aged 30-40 years[odds ratio(OR)=4.06,95%confidence interval(CI):1.04-15.82,P=0.043],middle school education(OR=3.98,95%CI:1.29-12.33,P=0.017),high school/technical secondary school education(OR=14.06,95%CI:3.92-50.38,P<0.001),and junior college/bachelor’s degree and above education(OR=15.20,95%CI:4.15-55.650,P<0.001)were independently associated with good knowledge.The higher knowledge score was independently associated with a positive attitude(OR=1.23,95%CI:1.11-1.36,P<0.001).The higher attitude score was independently associated with proactive practice(OR=1.20,95%CI:1.11-1.30,P<0.001).CONCLUSION Chinese patients with IBD might have good knowledge,a positive attitude,and proactive practice toward their disease.However,a small number of specific items require education.展开更多
BACKGROUND Ischemic bowel disease(IBD)is a critical condition caused by reduced blood flow to the intestines,leading to tissue damage and potentially severe complications.Early recognition and timely management are es...BACKGROUND Ischemic bowel disease(IBD)is a critical condition caused by reduced blood flow to the intestines,leading to tissue damage and potentially severe complications.Early recognition and timely management are essential for improving patient outcomes and reducing morbidity and mortality associated with IBD.AIM To evaluate the knowledge,attitude and practice(KAP)of healthcare professionals regarding IBD.METHODS This cross-sectional study was conducted among healthcare professionals in China from November 2023 to December 2023 using a self-designed questionnaire.RESULTS A total of 315 valid questionnaires were analyzed,with 215 participants(68.25%)being female.The mean KAP scores were 17.55±5.35(range:0-24),27.65±2.77(range:8-40),and 18.88±4.23(range:6-30),respectively.Multivariate linear regression analysis revealed the following factors to be independently associated with knowledge:Age 26-35 years(β=2.80,95%CI:0.31-5.30,P=0.028),professional title(β=2.66,95%CI:0.91-4.41,P=0.003),position(β=-3.78,95%CI:-5.45 to-2.11,P<0.001),participation in IBD-related training(β=3.45,95%CI:2.39-4.51,P<0.001),and admission of more than five IBD cases in the past month(β=3.25,95%CI:1.58-4.92,P<0.001).Attitude was independently associated with knowledge(β=0.20,95%CI:0.15-0.26,P<0.001)and being a nurse or nursing supervisor(β=-1.30,95%CI:-2.16 to-0.40,P=0.003).Practice was independently associated with knowledge(β=0.20,95%CI:0.10-0.30,P<0.001)and attitude(β=0.24,95%CI:0.06-0.42,P=0.007).Structural equation modeling demonstrated direct effects of knowledge on attitude(β=0.24,P<0.001)and practice(β=0.26,P<0.001),as well as of attitude on practice(β=0.22,P=0.012).CONCLUSION Healthcare professionals demonstrated adequate knowledge but moderate attitude and inactive practice regarding IBD.Addressing the gaps in attitude and practice through targeted training programs and interventions is essential for improving patient care and outcomes.展开更多
Introduction: The use of proper feeding practices is key for the overall development of children. Generally, breastfeeding and complementary feeding make up the diet and therefore the nutritional status of children. H...Introduction: The use of proper feeding practices is key for the overall development of children. Generally, breastfeeding and complementary feeding make up the diet and therefore the nutritional status of children. However, the degree to which mothers adhere to the recommendations of the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) regarding breastfeeding and complementary feeding is key to the nutritional status of children. Again, the adherence to this dietary recommendation is contingent on the socio-economic conditions of the child-bearing parents, especially the mothers. Here in this study, the socio-economic characteristics were analyzed along with the feeding practices of children not more than five years old in rural Sierra Leone. Method: Data were collected in 2017 on representative mothers with children within 0 - 5 years old. A total of 10 communities and 200 respondents were randomly covered in the Kori Chiefdom of Moyamba District, Sierra Leone. The data collection instruments included structured questionnaire, inter-personal interaction, personal observation and experience. The collected data were analyzed in Microsoft Excel and SPSS and the results presented in simple graphs. Results: A large number of the respondents were married teenage mothers with 1 - 2 children and living under extreme hardship by the United Nations (UN) standard. Also, most of the mothers were illiterate and started breastfeeding their children within the very hour of birth. Because complementary feeding was started all too early, exclusive breastfeeding last for not more than two months for most of the respondent mothers. Also, because rice is by far the most widely eaten the staple food in Sierra Leone, complementary food was mostly powdered rice mixed with salt and oil. Hardly was protein food supplement used as complementary food, probably due to the economic conditions of the poor rural women. Conclusion: The study has thrown sufficient light on the socio-economic characteristics and adopted feeding practices of children in poor rural Sierra Leone. In this sense, the study has laid the basis for sufficient for in-depth correlativity studies on the factors driving feeding practices of children and how it in turn impacts nutritional status of children in poor rural Africa. From here, practically adoptable recommendations can be advanced for the attention of the governments, public institutions, the private sector and the individuals of the society.展开更多
Economic & Philosophic Manuscripts of 1844 was regarded as the key text for studying Marx's aesthetics thoughts It was translated into Chinese in 1956 and then attracted Chinese scholars' attention. In the past hal...Economic & Philosophic Manuscripts of 1844 was regarded as the key text for studying Marx's aesthetics thoughts It was translated into Chinese in 1956 and then attracted Chinese scholars' attention. In the past half century it was the main theory source of Chinese Marxism aesthetics. There were two large scale debates on aesthetics related to Economic & Philosophic Manuscripts of 1844 in China. One was taken place in the late of 1950s to 1960s and the other was in 1980s. The main arguments concentrated on four issues in the Manuscripts of 1844: the relationship between practice and beauty, the meaning of the two standards and the law of beauty, whether estranged labour creates beauty or not, how to asses the Manuscripts.展开更多
In industrial plants, ships, and buildings, a large amount of gas and air ducts are applied for equipment connection, HVAC, medium transport, and exhaust, etc. These ducts can be designed in varied cross-sectional sha...In industrial plants, ships, and buildings, a large amount of gas and air ducts are applied for equipment connection, HVAC, medium transport, and exhaust, etc. These ducts can be designed in varied cross-sectional shapes, such as round or rectangle. The author reveals through geometric calculation of the duct cross-sectional shapes and engineering experiences that the round cross-section is an optimal shape in the duct system. The round duct has the shorter perimeter than the other cross-sectional shape ducts and the stronger structure in the same working condition. The material saving of the round duct due to the shorter perimeter is quantitatively determined. In the pater, it is shown that the round duct is economically attractive. The economic analysis for the material cost saving is illustrated by an example. For a long duct system, the material and material cost savings are significant. It is suggested that the round duct in the gas and air duct system should have priority as long as the field conditions are allowed. In the paper, the material cost saving is also converted to PW, AW, and FW used for LCC economic analysis.展开更多
AIM: To assess advanced neuroendocrine tumor (NET) treatment patterns and resource utilization by tumor progression stage and tumor site in the United States. METHODS: United States Physicians meeting eligibility crit...AIM: To assess advanced neuroendocrine tumor (NET) treatment patterns and resource utilization by tumor progression stage and tumor site in the United States. METHODS: United States Physicians meeting eligibility criteria were provided with online data extraction forms to collect patient chart data on recent NET patients. Resource utilization and treatment pattern data were collected over a baseline period (after diagnosis and before tumor progression), as well as initial and secondary progression periods, with progression defined according to measureable radiographic evidence of tumor progression. Resource categories used in the analysis include: Treatments (e.g. , surgery, chemotherapy, radiotherapy, targeted therapies), hospitalizations and physician visits, diagnostic tests (biomarkers, imaging, laboratory tests). Comparisons between categories of resource utilization and tumor progression status were examined using univariate (by tumor site) and multivariate analyses (across all tumor sites). RESULTS: Fifty-five physicians were included in the study and completed online data extraction forms using the charts of 110 patients. The physician sample showed a relatively even distribution for those affiliated with academic versus community hospitals (46% vs 55%). Forty (36.3%) patients were reported to have pancreatic NET (pNET), while 70 (63.6%) patients had gastrointestinal tract (GI)/Lung as the primary NET site. Univariate analysis showed the proportion of patients hospitalized increased from 32.7% during baseline to 42.1% in the progression stages. While surgeries were performed at similar proportions overall at baseline and progression, pNET patients, were more likely than GI/Lung NET patients to have undergone surgery during the baseline (33.3% vs 25.0%) and any progression periods (26.7% vs 23.4%). While peptide-receptor radionuclide and targeted therapy utilization was low across NET types and tumor stages, GI/Lung types exhibited greater utilization of these technologies compared to pNET. Chemotherapy utilization was also greater among GI/Lung types. Multivariate analysis results demonstrated that patients in first progression period were over 3 times more likely to receive chemotherapy when compared to baseline (odds ratio: 3.31; 95%CI: 1.46-7.48, P=0.0041). Further, progression was associated with a greater likelihood of having a study physician visit [relative risk (RR): 1.54; 95%CI: 1.10-2.17, P=0.0117], and an increased frequency of other physician visits (RR: 1.84; 95%CI: 1.10-3.10, P=0.0211). CONCLUSION: Resource utilization in advanced NET in the United States is significant overall and data suggests progression has an impact on resource utilization regardless of NET tumor site.展开更多
There is currently a dearth of information pertaining to socio-demographic factors and eating practices in a multicultural country like Mauritius. This study was therefore undertaken to probe the different eating prac...There is currently a dearth of information pertaining to socio-demographic factors and eating practices in a multicultural country like Mauritius. This study was therefore undertaken to probe the different eating practices among an adult sample population in Mauritius in an endeavor to establish significant relationships, if any, with common socio-demographic and socio-economic factors. A self-designed questionnaire, (randomly distributed to n = 387 adults), pertaining to socio-demographic variables, vegetarianism, breakfast patterns, eating out of home meals (OHMs), food frequency questions and dieting practices were asked. Males (21 - 40 yrs) had a significantly (p 0.05) to adherence to the recommendations for the consumption of fish. The socio-demographic factors most influential towards eating practices were gender, age and socio-economic status represented by education and occupation. In conclusion, relationships recorded in the present study were comparable to Western eating practices and the availability of certain foods has compelled Mauritians to develop its own and unique eating patterns which can be of relevance in providing accurate health targets for future nutrition interventions in Mauritius.展开更多
基金Supported by the Agricultural Science and Technology Innovation Funds of Jiangsu(cx(12)1001-04)~~
文摘Deep-Litter System is a high yield approach to raise swine with pollution free in a lower cost. In the research, based on the heat stress in summer caused by fermentation, three temperature-control systems were designed, including natural ventilation through transoms, forced ventilation via fans, and cooling by hyperbaric spray system. Specifically, the latter intermittent auto-pressurized spray system developed in our lab, which could spray successively via pressure from storage tubes without wetting the fermentation bed, is suitable for the promotion with the deep-litter technology in rural regions , since the power consumption is only 1 kwh per day.
基金This study was supported by Chinese nursing management scientific research fund(CNM-2017-09).
文摘Objective To identify the status of knowledge,attitude,and behaviour toward evidence-based practice(EBP)among Chinese psychiatric nurses,and to examine the influencing factors of EBP behaviour.Methods We utilised a cross-sectional design.A total of 923 psychiatric nurses from 168 hospitals in 27 provinces in the mainland of China participated in our survey.The EBP questionnaire,the barriers to research utilisation scale and the facilitators to research utilisation scale were used for data collection via WeChat group from July 2018 to April 2019.Multiple regression analysis was used to analyse the influencing factors of psychiatric nurses’evidence-based practice behaviour.Results The score of Chinese psychiatric nurses’EBP attitude,behaviour and knowledge were 4.81±1.34,4.11±1.36 and 3.53±1.29,respectively.Multiple regression analysis showed that nurses’EBP behaviour was mainly determined by knowledge and attitude,which together explained 61.8%of the variance.The two top barriers were the dimensions of presentation and research.Facilitators include managerial support,employing nurses with research skills as models and providing advanced education on evidence-based nursing.Conclusion Psychiatric nurses have positive attitudes toward EBP,but their level of knowledge and behaviour is insufficient.Heavy workload,insufficient time,and a lack of knowledge and skills is the main barrier.Managerial support,employing nurses with research skills as models and providing advanced education are the main facilitators.
基金Supported by Wenzhou Science and Technology Bureau,No.Y20220031.
文摘BACKGROUND Patients with inflammatory bowel diseases(IBDs)generally have poor knowledge,attitude,and practice of their disease,while the data from China are lacking.AIM To address this knowledge disparity among Chinese patients with IBD.METHODS This web-based,cross-sectional study was conducted on a cohort of IBD patients who visited the Second Affiliated Hospital of Wenzhou Medical University between December 2022 and February 2023.Their socio-demographic information and the knowledge,attitude,and practice scores were collected and estimated using a self-designed questionnaire.Pearson’s correlation analysis was used to determine the pairwise correlations among knowledge,attitude,and practice scores.A multivariate logistic regression analysis was further performed to determine the independent factors associated with their knowledge,attitude,and practice scores.RESULTS A total of 353 patients(224 males)with IBD completed the questionnaires.The mean knowledge,attitude,and practice scores were 10.05±3.46(possible range:0-14),41.58±5.23(possible range:0-56),44.20±7.39(possible range:0-56),respectively,indicating good knowledge,positive attitude,and proactive practice toward IBD.Pearson’s correlation analysis showed that the knowledge score had significant positive correlations with the attitude score(r=0.371,P<0.001)and practice score(r=0.100,P<0.001).The attitude score had a significant positive correlation with the practice score(r=0.452,P<0.001).Moreover,multivariate logistic regression analysis showed that aged 30-40 years[odds ratio(OR)=4.06,95%confidence interval(CI):1.04-15.82,P=0.043],middle school education(OR=3.98,95%CI:1.29-12.33,P=0.017),high school/technical secondary school education(OR=14.06,95%CI:3.92-50.38,P<0.001),and junior college/bachelor’s degree and above education(OR=15.20,95%CI:4.15-55.650,P<0.001)were independently associated with good knowledge.The higher knowledge score was independently associated with a positive attitude(OR=1.23,95%CI:1.11-1.36,P<0.001).The higher attitude score was independently associated with proactive practice(OR=1.20,95%CI:1.11-1.30,P<0.001).CONCLUSION Chinese patients with IBD might have good knowledge,a positive attitude,and proactive practice toward their disease.However,a small number of specific items require education.
文摘BACKGROUND Ischemic bowel disease(IBD)is a critical condition caused by reduced blood flow to the intestines,leading to tissue damage and potentially severe complications.Early recognition and timely management are essential for improving patient outcomes and reducing morbidity and mortality associated with IBD.AIM To evaluate the knowledge,attitude and practice(KAP)of healthcare professionals regarding IBD.METHODS This cross-sectional study was conducted among healthcare professionals in China from November 2023 to December 2023 using a self-designed questionnaire.RESULTS A total of 315 valid questionnaires were analyzed,with 215 participants(68.25%)being female.The mean KAP scores were 17.55±5.35(range:0-24),27.65±2.77(range:8-40),and 18.88±4.23(range:6-30),respectively.Multivariate linear regression analysis revealed the following factors to be independently associated with knowledge:Age 26-35 years(β=2.80,95%CI:0.31-5.30,P=0.028),professional title(β=2.66,95%CI:0.91-4.41,P=0.003),position(β=-3.78,95%CI:-5.45 to-2.11,P<0.001),participation in IBD-related training(β=3.45,95%CI:2.39-4.51,P<0.001),and admission of more than five IBD cases in the past month(β=3.25,95%CI:1.58-4.92,P<0.001).Attitude was independently associated with knowledge(β=0.20,95%CI:0.15-0.26,P<0.001)and being a nurse or nursing supervisor(β=-1.30,95%CI:-2.16 to-0.40,P=0.003).Practice was independently associated with knowledge(β=0.20,95%CI:0.10-0.30,P<0.001)and attitude(β=0.24,95%CI:0.06-0.42,P=0.007).Structural equation modeling demonstrated direct effects of knowledge on attitude(β=0.24,P<0.001)and practice(β=0.26,P<0.001),as well as of attitude on practice(β=0.22,P=0.012).CONCLUSION Healthcare professionals demonstrated adequate knowledge but moderate attitude and inactive practice regarding IBD.Addressing the gaps in attitude and practice through targeted training programs and interventions is essential for improving patient care and outcomes.
文摘Introduction: The use of proper feeding practices is key for the overall development of children. Generally, breastfeeding and complementary feeding make up the diet and therefore the nutritional status of children. However, the degree to which mothers adhere to the recommendations of the World Health Organization (WHO) and the United Nations Children’s Fund (UNICEF) regarding breastfeeding and complementary feeding is key to the nutritional status of children. Again, the adherence to this dietary recommendation is contingent on the socio-economic conditions of the child-bearing parents, especially the mothers. Here in this study, the socio-economic characteristics were analyzed along with the feeding practices of children not more than five years old in rural Sierra Leone. Method: Data were collected in 2017 on representative mothers with children within 0 - 5 years old. A total of 10 communities and 200 respondents were randomly covered in the Kori Chiefdom of Moyamba District, Sierra Leone. The data collection instruments included structured questionnaire, inter-personal interaction, personal observation and experience. The collected data were analyzed in Microsoft Excel and SPSS and the results presented in simple graphs. Results: A large number of the respondents were married teenage mothers with 1 - 2 children and living under extreme hardship by the United Nations (UN) standard. Also, most of the mothers were illiterate and started breastfeeding their children within the very hour of birth. Because complementary feeding was started all too early, exclusive breastfeeding last for not more than two months for most of the respondent mothers. Also, because rice is by far the most widely eaten the staple food in Sierra Leone, complementary food was mostly powdered rice mixed with salt and oil. Hardly was protein food supplement used as complementary food, probably due to the economic conditions of the poor rural women. Conclusion: The study has thrown sufficient light on the socio-economic characteristics and adopted feeding practices of children in poor rural Sierra Leone. In this sense, the study has laid the basis for sufficient for in-depth correlativity studies on the factors driving feeding practices of children and how it in turn impacts nutritional status of children in poor rural Africa. From here, practically adoptable recommendations can be advanced for the attention of the governments, public institutions, the private sector and the individuals of the society.
基金Acknowledgements: This paper was sponsored by China National Social Science Foundation "Research on the Fundamental Problems of the Contemporary Aesthetics and Criticism Patterns" (15ZDB023).
文摘Economic & Philosophic Manuscripts of 1844 was regarded as the key text for studying Marx's aesthetics thoughts It was translated into Chinese in 1956 and then attracted Chinese scholars' attention. In the past half century it was the main theory source of Chinese Marxism aesthetics. There were two large scale debates on aesthetics related to Economic & Philosophic Manuscripts of 1844 in China. One was taken place in the late of 1950s to 1960s and the other was in 1980s. The main arguments concentrated on four issues in the Manuscripts of 1844: the relationship between practice and beauty, the meaning of the two standards and the law of beauty, whether estranged labour creates beauty or not, how to asses the Manuscripts.
文摘In industrial plants, ships, and buildings, a large amount of gas and air ducts are applied for equipment connection, HVAC, medium transport, and exhaust, etc. These ducts can be designed in varied cross-sectional shapes, such as round or rectangle. The author reveals through geometric calculation of the duct cross-sectional shapes and engineering experiences that the round cross-section is an optimal shape in the duct system. The round duct has the shorter perimeter than the other cross-sectional shape ducts and the stronger structure in the same working condition. The material saving of the round duct due to the shorter perimeter is quantitatively determined. In the pater, it is shown that the round duct is economically attractive. The economic analysis for the material cost saving is illustrated by an example. For a long duct system, the material and material cost savings are significant. It is suggested that the round duct in the gas and air duct system should have priority as long as the field conditions are allowed. In the paper, the material cost saving is also converted to PW, AW, and FW used for LCC economic analysis.
基金Supported by Novartis Pharmaceuticals Corporation, Florham Park, NJ 07932, to Liu Z, Wang X and Grzegorzewski KJLA-SER Analytica, to Casciano R, Stern L, Parikh R, Chulikavit Mand Willet J
文摘AIM: To assess advanced neuroendocrine tumor (NET) treatment patterns and resource utilization by tumor progression stage and tumor site in the United States. METHODS: United States Physicians meeting eligibility criteria were provided with online data extraction forms to collect patient chart data on recent NET patients. Resource utilization and treatment pattern data were collected over a baseline period (after diagnosis and before tumor progression), as well as initial and secondary progression periods, with progression defined according to measureable radiographic evidence of tumor progression. Resource categories used in the analysis include: Treatments (e.g. , surgery, chemotherapy, radiotherapy, targeted therapies), hospitalizations and physician visits, diagnostic tests (biomarkers, imaging, laboratory tests). Comparisons between categories of resource utilization and tumor progression status were examined using univariate (by tumor site) and multivariate analyses (across all tumor sites). RESULTS: Fifty-five physicians were included in the study and completed online data extraction forms using the charts of 110 patients. The physician sample showed a relatively even distribution for those affiliated with academic versus community hospitals (46% vs 55%). Forty (36.3%) patients were reported to have pancreatic NET (pNET), while 70 (63.6%) patients had gastrointestinal tract (GI)/Lung as the primary NET site. Univariate analysis showed the proportion of patients hospitalized increased from 32.7% during baseline to 42.1% in the progression stages. While surgeries were performed at similar proportions overall at baseline and progression, pNET patients, were more likely than GI/Lung NET patients to have undergone surgery during the baseline (33.3% vs 25.0%) and any progression periods (26.7% vs 23.4%). While peptide-receptor radionuclide and targeted therapy utilization was low across NET types and tumor stages, GI/Lung types exhibited greater utilization of these technologies compared to pNET. Chemotherapy utilization was also greater among GI/Lung types. Multivariate analysis results demonstrated that patients in first progression period were over 3 times more likely to receive chemotherapy when compared to baseline (odds ratio: 3.31; 95%CI: 1.46-7.48, P=0.0041). Further, progression was associated with a greater likelihood of having a study physician visit [relative risk (RR): 1.54; 95%CI: 1.10-2.17, P=0.0117], and an increased frequency of other physician visits (RR: 1.84; 95%CI: 1.10-3.10, P=0.0211). CONCLUSION: Resource utilization in advanced NET in the United States is significant overall and data suggests progression has an impact on resource utilization regardless of NET tumor site.
文摘There is currently a dearth of information pertaining to socio-demographic factors and eating practices in a multicultural country like Mauritius. This study was therefore undertaken to probe the different eating practices among an adult sample population in Mauritius in an endeavor to establish significant relationships, if any, with common socio-demographic and socio-economic factors. A self-designed questionnaire, (randomly distributed to n = 387 adults), pertaining to socio-demographic variables, vegetarianism, breakfast patterns, eating out of home meals (OHMs), food frequency questions and dieting practices were asked. Males (21 - 40 yrs) had a significantly (p 0.05) to adherence to the recommendations for the consumption of fish. The socio-demographic factors most influential towards eating practices were gender, age and socio-economic status represented by education and occupation. In conclusion, relationships recorded in the present study were comparable to Western eating practices and the availability of certain foods has compelled Mauritians to develop its own and unique eating patterns which can be of relevance in providing accurate health targets for future nutrition interventions in Mauritius.