目的检索我国已发表关于实效性随机对照试验(pRCT)的文献,分析当前pRCT研究现状与热点。方法检索中国知网、万方和Web of Science数据库自建库以来至2021年7月31日我国学者发表的pRCT相关文献,采用CiteSpace软件分析作者、发文机构、关...目的检索我国已发表关于实效性随机对照试验(pRCT)的文献,分析当前pRCT研究现状与热点。方法检索中国知网、万方和Web of Science数据库自建库以来至2021年7月31日我国学者发表的pRCT相关文献,采用CiteSpace软件分析作者、发文机构、关键词和突变词。结果共发表中英文文献196篇,发文量呈逐年增长趋势;79篇中文文献分布在44种期刊上,117篇英文文献分布在71种期刊上;中文文献发文量最多的为中国中医科学院中医临床基础医学研究所(7篇),英文文献发文量最多的机构为香港大学(34篇);中文文献聚类标签词分别为临床试验、随机对照试验、循证医学、中医综合方案、临床试验方案、临床研究和药物经济学,英文文献聚类结果有待进一步凝练;中英文文献分别产生4个和5个突现词,突现词持续时间只有1~3年。结论我国pRCT研究热点主要集中在中医临床试验综合方案、真实世界研究中的临床试验、循证医学和药物经济学4个领域,但该研究核心作者较少、研究机构分散,机构间合作有待加强。展开更多
Over the last few years a number of large acupuncture trials have been carried out in western countries. The following article draws on the experience from these recent large-scale trials on acupuncture to outline the...Over the last few years a number of large acupuncture trials have been carried out in western countries. The following article draws on the experience from these recent large-scale trials on acupuncture to outline the way randomized trials could be used to answer questions on efficacy, effectiveness and efficiency. It will provide guidance, firstly on the underlying concepts of both efficacy and effectiveness and secondly on designing both types of trials. In addition, the controversy over specific and non-specific effects of acupuncture, emerging from the results of the above-mentioned trials, will be highlighted. Suggestions for future clinical research on acupuncture include： greater reflection on the complex approach of Chinese medicine, and transparent and detailed reporting according to CONSORT and STRICTA guidelines. The current data on acupuncture point-specific effects do indeed have relevance, however for valid decision-making on acupuncture, further clinical trials on effectiveness and cost-effectiveness are required to provide realistic benefit estimates for future health care.展开更多
文摘目的检索我国已发表关于实效性随机对照试验(pRCT)的文献,分析当前pRCT研究现状与热点。方法检索中国知网、万方和Web of Science数据库自建库以来至2021年7月31日我国学者发表的pRCT相关文献,采用CiteSpace软件分析作者、发文机构、关键词和突变词。结果共发表中英文文献196篇,发文量呈逐年增长趋势;79篇中文文献分布在44种期刊上,117篇英文文献分布在71种期刊上;中文文献发文量最多的为中国中医科学院中医临床基础医学研究所(7篇),英文文献发文量最多的机构为香港大学(34篇);中文文献聚类标签词分别为临床试验、随机对照试验、循证医学、中医综合方案、临床试验方案、临床研究和药物经济学,英文文献聚类结果有待进一步凝练;中英文文献分别产生4个和5个突现词,突现词持续时间只有1~3年。结论我国pRCT研究热点主要集中在中医临床试验综合方案、真实世界研究中的临床试验、循证医学和药物经济学4个领域,但该研究核心作者较少、研究机构分散,机构间合作有待加强。
文摘Over the last few years a number of large acupuncture trials have been carried out in western countries. The following article draws on the experience from these recent large-scale trials on acupuncture to outline the way randomized trials could be used to answer questions on efficacy, effectiveness and efficiency. It will provide guidance, firstly on the underlying concepts of both efficacy and effectiveness and secondly on designing both types of trials. In addition, the controversy over specific and non-specific effects of acupuncture, emerging from the results of the above-mentioned trials, will be highlighted. Suggestions for future clinical research on acupuncture include： greater reflection on the complex approach of Chinese medicine, and transparent and detailed reporting according to CONSORT and STRICTA guidelines. The current data on acupuncture point-specific effects do indeed have relevance, however for valid decision-making on acupuncture, further clinical trials on effectiveness and cost-effectiveness are required to provide realistic benefit estimates for future health care.
