Hollow-core negative curvature fibers(HC-NCFs)have become one of the research hotspots in the field of optical fiber because of their potential applications in the data and energy transmissions.In this work,a new kind...Hollow-core negative curvature fibers(HC-NCFs)have become one of the research hotspots in the field of optical fiber because of their potential applications in the data and energy transmissions.In this work,a new kind of single-polarization single-mode HC-NCF with nested U-type cladding elements is proposed.To achieve the single-polarization single-mode transmission,we use two different silica tubes in thickness,which satisfy the resonance and anti-resonance conditions on the U-type cladding elements and the cladding tubes,respectively.Besides,the elliptical elements are introduced to achieve good single-mode performance.By studying the influences of the structure parameters on the propagation characteristics,the optimized structure parameters are obtained.The simulation results show that when the wavelength is fixed at 1550 nm,the single-polarization single-mode transmission is achieved,with the polarization extinction ratio of 25749 and minimum high-order mode extinction ratio of 174.Furthermore,the confinement loss is only 0.0015 dB/m.展开更多
The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the 5' flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) simil...The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the 5' flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) similar to NF-кB consensus sequence resides in the negative regulatory element (-3028bp～ -2902bp, termed ε-NRAII) 5' to the cap site of this gene. NRF DNA fragment (-3010bp～ -2986bp) containing the NF-кB motif similar sequence was synthesized and used in electrophoresis mobility shift assay (EMSA) and competitive analysis. Data showed that a protein factor from nuclear extracts of K562 cells specifically interacted with NRF DNA fragment. The synthetic NF DNA fragment (containing NF-кB consensus sequence) could competed for the protein binding, but MNF DNA fragment (mutated NF-кB motif) could not, suggesting that the binding protein is a member of NF-кB/Rel family. Western blot assay demonstrated that the molecular weight of NF-кB protein in the nuclei of K562 cells is 50ku. We suggested that NF-кB p50 may play an important role in the regulation of human c-globin gene expression.展开更多
The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the 5’ flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) similar ...The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the 5’ flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) similar to NF-кB consensus sequence resides in the negative regulatory element (-3028bp～ -2902bp, termed ε-NRAII) 5’ to the cap site of this gene. NRF DNA fragment (-3010bp～ -2986bp) containing the NF-кB motif similar sequence was synthesized and used in electrophoresis mobility shift assay (EMSA) and competitive analysis. Data showed that a protein factor from nuclear extracts of K562 cells specifically interacted with NRF DNA fragment. The synthetic NF DNA fragment (containing NF-кB consensus sequence) could competed for the protein binding, but MNF DNA fragment (mutated NF-кB motif) could not, suggesting that the binding protein is a member of NF-кB/Rel family. Western blot assay demonstrated that the molecular weight of NF-кB protein in the nuclei of K562 cells is 50ku. We suggested that NF-кB p50 may play an important role in the regulation of human c-globin gene expression.展开更多
The purpose of this article is to develop and analyze least-squares approximations for the incompressible magnetohydrodynamic equations. The major advantage of the least-squares finite element method is that it is not...The purpose of this article is to develop and analyze least-squares approximations for the incompressible magnetohydrodynamic equations. The major advantage of the least-squares finite element method is that it is not subjected to the so-called Ladyzhenskaya-Babuska-Brezzi （LBB） condition. The authors employ least-squares functionals which involve a discrete inner product which is related to the inner product in H^-1（Ω）.展开更多
A finite element program with two different soil models is adopted to study the negative skin friction of an unloaded single pile embedded in the settlement trough of a tunnel. The results show that it is necessary to...A finite element program with two different soil models is adopted to study the negative skin friction of an unloaded single pile embedded in the settlement trough of a tunnel. The results show that it is necessary to consider the nonlinear property of soil and to set interface elements between piles and soil in analysis of the negative skin friction of piles. Among a pile group, the pile located above the tunnel centerline bears larger downdrag than the ones far away from tunnel centerline.展开更多
While illustrating the process and the essence of listening and analyzing various subjective and objective barriers in listening, the author tries to show that English learners can improve their quality of listening c...While illustrating the process and the essence of listening and analyzing various subjective and objective barriers in listening, the author tries to show that English learners can improve their quality of listening comprehension by transferring the negative elements to the positive ones.展开更多
Peridotites from the southern Mariana forearc were sampled on the landward trench slope of the Izu-Bonin-Mariana (IBM) subduction zone by dredging.These mantle wedge peridotites underwent hydration by fluid derived fr...Peridotites from the southern Mariana forearc were sampled on the landward trench slope of the Izu-Bonin-Mariana (IBM) subduction zone by dredging.These mantle wedge peridotites underwent hydration by fluid derived from a dehydrated descending slab,and later interacted with seawater after emplacement at or near the seafloor.This study investigates how these two different rock-fluid interaction processes influenced trace element distribution in the southern Mariana forearc peridotites.We measured trace element concentrations of peridotites from the southern Mariana forearc.The southern Mariana forearc peridotites are characterized by a distinct seawater-like REE pattern with an obvious negative Ce anomaly,and La shows good correlation with other REEs (except Ce).In addition,there is a great enrichment of U,Pb,Sr and Li elements,which show a distinct positive anomaly relative to adjacent elements in the multi-element diagram.For the seawater-like REE pattern,we infer that REEs are mainly influenced by seawater during peridotite-seawater interactions after their emplacement at or near the seafloor,by serpentinization or by marine weathering.Furthermore,the anomalous behavior of Ce,compared with other rare earth elements in these samples,may indicate that they have undergone reactions involving Ce (IV) when the peridotites interacted with seawater.Positive U,Pb,Sr and Li anomalies are inferred to be related to seawater and/or fluids released during dehydration of the subducting slab.展开更多
Total platinum-group elements （PGEs） abundances in basalts from the spreading axis of Mariana Trough ranged from 0.418 × 10^9 to 1. 022 × 10^-9, and primitive mantle-normalized PGE patterns are of positive...Total platinum-group elements （PGEs） abundances in basalts from the spreading axis of Mariana Trough ranged from 0.418 × 10^9 to 1. 022 × 10^-9, and primitive mantle-normalized PGE patterns are of positive slope showing the relative enrichment of PPGE （ platinum, palladium, rhodium） and gold relative to IPGE. Compared with other mantle-originated rocks, these basalts have lower PGE contents and wider ranges of primitive mantle-normalized ratios of palladium content to iridium one, palladium content to platinum one and palladium content to gold one exhibiting relative platinum and iridium depletion. Characteristics of PGE patterns indicated that the studied Mariana Trough basalts originated from low partial melting, and the MORB mantle beneath the spreading center had been contaminated by the are-island mantle. In the aspect of trace elements, Mariana Trough basalts showed the enrichment of LILE, lead and LREE, indicating that they had been influenced by subduetion compositions. All these demonstrated that Mariana Trough basalts are products of partial melting from a mixed mantle （ the contamination of MORB mantle by are-island mantle）.展开更多
Four-dimensional(4D)printing,integrates transformation information into three-dimensional(3D)-printed structures,which means that 3D-printed structures are able to change their shapes,properties,or functionalities ove...Four-dimensional(4D)printing,integrates transformation information into three-dimensional(3D)-printed structures,which means that 3D-printed structures are able to change their shapes,properties,or functionalities over time.Here,two types of shape memory personalized vascular stents with negative Poisson’s ratio structure are developed via 4D printing.The genetic algorithm is used to optimize the structure.Axial compression tests,radial compression tests and three-point bending tests are carried out to study the mechanical properties of the stents.In addition,fluid-structure interaction and stress distribution during the shape recovery process are investigated based on finite element method.The shape memory behaviors of the stents are excellent and in vitro feasibility tests demonstrate that the stents can expand the simulated narrow blood vessel rapidly.Therefore,4D printed shape memory stents with negative Poisson’s ratio structure are highly promising for the treatment of vascular stenosis.展开更多
Voltage sag is one of the most common power quality disturbances in industry,which causes huge inrush currents in stator windings of induction motors,and adversely impacts the motor secure operation.This paper firstly...Voltage sag is one of the most common power quality disturbances in industry,which causes huge inrush currents in stator windings of induction motors,and adversely impacts the motor secure operation.This paper firstly introduces a 2D Time-Stepping multi-slice finite element method(2D T-S multi-slice FEM)which is used for calculating the magnetic field distribution in induction motors under different sag events.Then the paper deduces the transient analytical expression of stator inrush current based on the classical theory of AC motors and presents a separation method for the positive,negative and zero sequence values based on instantaneous currents.With this method,the paper studies the influences of voltage sag amplitude,phase-angle jump and initial phase angle on the stator positive-and negative-sequence peak currents of 5.5 kW and 55 kW induction motors.This paper further proposes a motor protection method under voltage sag condition with the stator negative-sequence peak currents as the protection threshold,so that the protection false trip can be avoided effectively.Finally,the calculation and analysis results are validated by the comparison of calculated and measured stator peak value of the 5.5 kW induction motor.展开更多
The cut-off negative pressure method is one of effective approaches to solve the seepage flow with free surface. According to the characteristics of this method, however, it has been found out that the deficiency of t...The cut-off negative pressure method is one of effective approaches to solve the seepage flow with free surface. According to the characteristics of this method, however, it has been found out that the deficiency of the algorithms is to easily cause inaccurate simulation in the vicinity of free surface owing to the penalty function with only one controlling penalty parameter. Therefore, an improved cut-off pressure method was presented by constructing penalty function with two controlling penalty parameters. The improved algorithms were illustrated to be able to improve the simulation accuracy and raise the convergence speed through considering the effects of the partially saturated or unsaturated elements more reasonably and calculating the nodal external forces more accurately. Finally, the improved cut-off negative pressure method was applied to the simulation of unsteady seepage flow with free surface, and the corresponding program codes were developed with validation of some cases.展开更多
基金supported by the National Natural Science Foundation of China(Grant No.61935007)。
文摘Hollow-core negative curvature fibers(HC-NCFs)have become one of the research hotspots in the field of optical fiber because of their potential applications in the data and energy transmissions.In this work,a new kind of single-polarization single-mode HC-NCF with nested U-type cladding elements is proposed.To achieve the single-polarization single-mode transmission,we use two different silica tubes in thickness,which satisfy the resonance and anti-resonance conditions on the U-type cladding elements and the cladding tubes,respectively.Besides,the elliptical elements are introduced to achieve good single-mode performance.By studying the influences of the structure parameters on the propagation characteristics,the optimized structure parameters are obtained.The simulation results show that when the wavelength is fixed at 1550 nm,the single-polarization single-mode transmission is achieved,with the polarization extinction ratio of 25749 and minimum high-order mode extinction ratio of 174.Furthermore,the confinement loss is only 0.0015 dB/m.
基金This work was supported by National Natural Sciences Foun-dation of China, No. 39893320 and No. 39870378.
文摘The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the 5' flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) similar to NF-кB consensus sequence resides in the negative regulatory element (-3028bp～ -2902bp, termed ε-NRAII) 5' to the cap site of this gene. NRF DNA fragment (-3010bp～ -2986bp) containing the NF-кB motif similar sequence was synthesized and used in electrophoresis mobility shift assay (EMSA) and competitive analysis. Data showed that a protein factor from nuclear extracts of K562 cells specifically interacted with NRF DNA fragment. The synthetic NF DNA fragment (containing NF-кB consensus sequence) could competed for the protein binding, but MNF DNA fragment (mutated NF-кB motif) could not, suggesting that the binding protein is a member of NF-кB/Rel family. Western blot assay demonstrated that the molecular weight of NF-кB protein in the nuclei of K562 cells is 50ku. We suggested that NF-кB p50 may play an important role in the regulation of human c-globin gene expression.
基金This work was supported by National Natural Sciences Foun-dation of China, No. 39893320 and No. 39870378.
文摘The developmental control of the human e-globin gene expression is mediated by transcription regulatory elements in the 5’ flanking DNA of this gene. Sequence analysis has revealed a DNA motif (GGGGAATTTGCT) similar to NF-кB consensus sequence resides in the negative regulatory element (-3028bp～ -2902bp, termed ε-NRAII) 5’ to the cap site of this gene. NRF DNA fragment (-3010bp～ -2986bp) containing the NF-кB motif similar sequence was synthesized and used in electrophoresis mobility shift assay (EMSA) and competitive analysis. Data showed that a protein factor from nuclear extracts of K562 cells specifically interacted with NRF DNA fragment. The synthetic NF DNA fragment (containing NF-кB consensus sequence) could competed for the protein binding, but MNF DNA fragment (mutated NF-кB motif) could not, suggesting that the binding protein is a member of NF-кB/Rel family. Western blot assay demonstrated that the molecular weight of NF-кB protein in the nuclei of K562 cells is 50ku. We suggested that NF-кB p50 may play an important role in the regulation of human c-globin gene expression.
基金supported by the National Basic Research Program of China (2005CB321701)NSF of mathematics research special fund of Hebei Province(08M005)
文摘The purpose of this article is to develop and analyze least-squares approximations for the incompressible magnetohydrodynamic equations. The major advantage of the least-squares finite element method is that it is not subjected to the so-called Ladyzhenskaya-Babuska-Brezzi （LBB） condition. The authors employ least-squares functionals which involve a discrete inner product which is related to the inner product in H^-1（Ω）.
文摘A finite element program with two different soil models is adopted to study the negative skin friction of an unloaded single pile embedded in the settlement trough of a tunnel. The results show that it is necessary to consider the nonlinear property of soil and to set interface elements between piles and soil in analysis of the negative skin friction of piles. Among a pile group, the pile located above the tunnel centerline bears larger downdrag than the ones far away from tunnel centerline.
文摘While illustrating the process and the essence of listening and analyzing various subjective and objective barriers in listening, the author tries to show that English learners can improve their quality of listening comprehension by transferring the negative elements to the positive ones.
基金Supported by the Pilot Project of Knowledge Innovation Project,Chinese Academy of Sciences (Nos.KZCX2-YW-211, KZCX3-SW-223)the National Natural Science Foundation of China (No.40830849)the Special Foundation for the Eleventh Five-Year Plan of COMRA (No.DYXM-115-02-1-03)
文摘Peridotites from the southern Mariana forearc were sampled on the landward trench slope of the Izu-Bonin-Mariana (IBM) subduction zone by dredging.These mantle wedge peridotites underwent hydration by fluid derived from a dehydrated descending slab,and later interacted with seawater after emplacement at or near the seafloor.This study investigates how these two different rock-fluid interaction processes influenced trace element distribution in the southern Mariana forearc peridotites.We measured trace element concentrations of peridotites from the southern Mariana forearc.The southern Mariana forearc peridotites are characterized by a distinct seawater-like REE pattern with an obvious negative Ce anomaly,and La shows good correlation with other REEs (except Ce).In addition,there is a great enrichment of U,Pb,Sr and Li elements,which show a distinct positive anomaly relative to adjacent elements in the multi-element diagram.For the seawater-like REE pattern,we infer that REEs are mainly influenced by seawater during peridotite-seawater interactions after their emplacement at or near the seafloor,by serpentinization or by marine weathering.Furthermore,the anomalous behavior of Ce,compared with other rare earth elements in these samples,may indicate that they have undergone reactions involving Ce (IV) when the peridotites interacted with seawater.Positive U,Pb,Sr and Li anomalies are inferred to be related to seawater and/or fluids released during dehydration of the subducting slab.
基金This study was supported by the National Natural Science Foundation of China under contract No. 40273025the National High Technology Research and Development of China under contract No. 2006AA09Z219+1 种基金the Key Laboratory of Marine Sedimentology and Environmental Geology, the State 0ceanic Administrationthe National Basic Research Program of China under contract No. G2000078503.
文摘Total platinum-group elements （PGEs） abundances in basalts from the spreading axis of Mariana Trough ranged from 0.418 × 10^9 to 1. 022 × 10^-9, and primitive mantle-normalized PGE patterns are of positive slope showing the relative enrichment of PPGE （ platinum, palladium, rhodium） and gold relative to IPGE. Compared with other mantle-originated rocks, these basalts have lower PGE contents and wider ranges of primitive mantle-normalized ratios of palladium content to iridium one, palladium content to platinum one and palladium content to gold one exhibiting relative platinum and iridium depletion. Characteristics of PGE patterns indicated that the studied Mariana Trough basalts originated from low partial melting, and the MORB mantle beneath the spreading center had been contaminated by the are-island mantle. In the aspect of trace elements, Mariana Trough basalts showed the enrichment of LILE, lead and LREE, indicating that they had been influenced by subduetion compositions. All these demonstrated that Mariana Trough basalts are products of partial melting from a mixed mantle （ the contamination of MORB mantle by are-island mantle）.
基金supported by the National Natural Science Foundation of China(Grant Nos.11632005 and 11672086)。
文摘Four-dimensional(4D)printing,integrates transformation information into three-dimensional(3D)-printed structures,which means that 3D-printed structures are able to change their shapes,properties,or functionalities over time.Here,two types of shape memory personalized vascular stents with negative Poisson’s ratio structure are developed via 4D printing.The genetic algorithm is used to optimize the structure.Axial compression tests,radial compression tests and three-point bending tests are carried out to study the mechanical properties of the stents.In addition,fluid-structure interaction and stress distribution during the shape recovery process are investigated based on finite element method.The shape memory behaviors of the stents are excellent and in vitro feasibility tests demonstrate that the stents can expand the simulated narrow blood vessel rapidly.Therefore,4D printed shape memory stents with negative Poisson’s ratio structure are highly promising for the treatment of vascular stenosis.
基金This work was supported in part by the National Natural Science Foundation of China under Grant51307050。
文摘Voltage sag is one of the most common power quality disturbances in industry,which causes huge inrush currents in stator windings of induction motors,and adversely impacts the motor secure operation.This paper firstly introduces a 2D Time-Stepping multi-slice finite element method(2D T-S multi-slice FEM)which is used for calculating the magnetic field distribution in induction motors under different sag events.Then the paper deduces the transient analytical expression of stator inrush current based on the classical theory of AC motors and presents a separation method for the positive,negative and zero sequence values based on instantaneous currents.With this method,the paper studies the influences of voltage sag amplitude,phase-angle jump and initial phase angle on the stator positive-and negative-sequence peak currents of 5.5 kW and 55 kW induction motors.This paper further proposes a motor protection method under voltage sag condition with the stator negative-sequence peak currents as the protection threshold,so that the protection false trip can be avoided effectively.Finally,the calculation and analysis results are validated by the comparison of calculated and measured stator peak value of the 5.5 kW induction motor.
文摘The cut-off negative pressure method is one of effective approaches to solve the seepage flow with free surface. According to the characteristics of this method, however, it has been found out that the deficiency of the algorithms is to easily cause inaccurate simulation in the vicinity of free surface owing to the penalty function with only one controlling penalty parameter. Therefore, an improved cut-off pressure method was presented by constructing penalty function with two controlling penalty parameters. The improved algorithms were illustrated to be able to improve the simulation accuracy and raise the convergence speed through considering the effects of the partially saturated or unsaturated elements more reasonably and calculating the nodal external forces more accurately. Finally, the improved cut-off negative pressure method was applied to the simulation of unsteady seepage flow with free surface, and the corresponding program codes were developed with validation of some cases.
