Acute pancreatitis during pregnancy is a rare event,and can be associated with high maternal mortality and fetal loss.Gallstone disease is thought to be the most common causative factor of acute pancreatitis,but,in ma...Acute pancreatitis during pregnancy is a rare event,and can be associated with high maternal mortality and fetal loss.Gallstone disease is thought to be the most common causative factor of acute pancreatitis,but,in many cases,the cause remains unclear.We report a case of a 36-year-old woman at 35 wk of gestation,who presented with severe pain confined to the upper abdomen and radiating to the back.The patient was diagnosed with acute idiopathic pancreatitis,which was managed conservatively;she recovered within several days and then delivered a healthy baby.Therefore it is important to consider acute pancreatitis when a pregnant woman presents with upper abdominal pain,nausea and vomiting in order to improve fetal and maternal outcomes for patients with acute pancreatitis.展开更多
妊娠期肝内胆汁淤积症（intrahepatic cholestasis of pregnancy,ICP）是一种重要的妊娠期并发症,主要导致围产儿死亡率增加。其发病有明显的地域和种族差异,迄今国际上尚无有关ICP的统一诊治意见。2011年,中华医学会妇产科学分会产科...妊娠期肝内胆汁淤积症（intrahepatic cholestasis of pregnancy,ICP）是一种重要的妊娠期并发症,主要导致围产儿死亡率增加。其发病有明显的地域和种族差异,迄今国际上尚无有关ICP的统一诊治意见。2011年,中华医学会妇产科学分会产科学组组织国内有关专家,制订了第1版《妊娠期肝内胆汁淤积症诊疗指南》,该指南的发表对我国ICP诊治的规范起到了重要的指导作用。近年来,在ICP诊治方面又有了新的认识,为此,对其进行了重新修订。ICP曾有过许多命名,也引起了诊断和治疗的混乱,自第1版ICP诊疗指南发表后,展开更多
目的：观察妊娠早期单纯甲状腺过氧化物酶抗体（thyroid peroxidase antibody,TPO-Ab）阳性,是否会增加孕产妇妊娠并发症的发生和影响妊娠结局。方法：收集孕周≤13周且甲状腺功能正常孕妇的临床资料,根据TPO-Ab检测结果将患者分为TPO-A...目的：观察妊娠早期单纯甲状腺过氧化物酶抗体（thyroid peroxidase antibody,TPO-Ab）阳性,是否会增加孕产妇妊娠并发症的发生和影响妊娠结局。方法：收集孕周≤13周且甲状腺功能正常孕妇的临床资料,根据TPO-Ab检测结果将患者分为TPO-Ab（-）组（〈60 k U/L,793例）和TPO-Ab（＋）组（≥60 k U/L,88例）。随访患者甲状腺功能的变化,比较2组患者妊娠结局的差异。结果：TPO-Ab（＋）组患者促甲状腺激素（TSH）高于TPO-Ab（-）组（t=2.079,P=0.038）;TPO-Ab（＋）组患者胎膜早破、胎儿生长受限（FGR）和低出生体质量儿的发生率高于TPO-Ab（-）组（7.95%vs.1.89%,χ^2=9.598,P=0.002;2.27%vs.0.37%,χ^2=5.126,P=0.024;5.68%vs.2.12%,χ^2=4.180,P=0.041）。结论：TPO-Ab阳性对妊娠期间并发症和妊娠结局存在不良影响。展开更多
文摘Acute pancreatitis during pregnancy is a rare event,and can be associated with high maternal mortality and fetal loss.Gallstone disease is thought to be the most common causative factor of acute pancreatitis,but,in many cases,the cause remains unclear.We report a case of a 36-year-old woman at 35 wk of gestation,who presented with severe pain confined to the upper abdomen and radiating to the back.The patient was diagnosed with acute idiopathic pancreatitis,which was managed conservatively;she recovered within several days and then delivered a healthy baby.Therefore it is important to consider acute pancreatitis when a pregnant woman presents with upper abdominal pain,nausea and vomiting in order to improve fetal and maternal outcomes for patients with acute pancreatitis.
文摘妊娠期肝内胆汁淤积症（intrahepatic cholestasis of pregnancy,ICP）是一种重要的妊娠期并发症,主要导致围产儿死亡率增加。其发病有明显的地域和种族差异,迄今国际上尚无有关ICP的统一诊治意见。2011年,中华医学会妇产科学分会产科学组组织国内有关专家,制订了第1版《妊娠期肝内胆汁淤积症诊疗指南》,该指南的发表对我国ICP诊治的规范起到了重要的指导作用。近年来,在ICP诊治方面又有了新的认识,为此,对其进行了重新修订。ICP曾有过许多命名,也引起了诊断和治疗的混乱,自第1版ICP诊疗指南发表后,
文摘目的：观察妊娠早期单纯甲状腺过氧化物酶抗体（thyroid peroxidase antibody,TPO-Ab）阳性,是否会增加孕产妇妊娠并发症的发生和影响妊娠结局。方法：收集孕周≤13周且甲状腺功能正常孕妇的临床资料,根据TPO-Ab检测结果将患者分为TPO-Ab（-）组（〈60 k U/L,793例）和TPO-Ab（＋）组（≥60 k U/L,88例）。随访患者甲状腺功能的变化,比较2组患者妊娠结局的差异。结果：TPO-Ab（＋）组患者促甲状腺激素（TSH）高于TPO-Ab（-）组（t=2.079,P=0.038）;TPO-Ab（＋）组患者胎膜早破、胎儿生长受限（FGR）和低出生体质量儿的发生率高于TPO-Ab（-）组（7.95%vs.1.89%,χ^2=9.598,P=0.002;2.27%vs.0.37%,χ^2=5.126,P=0.024;5.68%vs.2.12%,χ^2=4.180,P=0.041）。结论：TPO-Ab阳性对妊娠期间并发症和妊娠结局存在不良影响。
